Safdarjang Hospital and Vardhman Mahavir Medical College

Delhi, India

Safdarjang Hospital and Vardhman Mahavir Medical College

Delhi, India

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Darmstadt G.L.,Stanford University | Howson C.P.,March of Dimes Foundation | Armstrong R.W.,Aga Khan University | Blencowe H.K.,London School of Hygiene and Tropical Medicine | And 80 more authors.
JAMA Pediatrics | Year: 2016

As the Sustainable Development Goals are adopted by United Nations member states, children with congenital disorders remain left behind in policies, programs, research, and funding. Although this finding was recognized by the creation and endorsement of the 63rd World Health Assembly Resolution in 2010 calling on United Nations member states to strengthen prevention of congenital disorders and the improvement of care of those affected, there has been little to no action since then. The Sustainable Development Goals call for the global health and development community to focus first and foremost on the most vulnerable and those left behind in the Millennium Development Goal era. To maximize the opportunity for every woman and couple to have a healthy child and to reduce the mortality and severe disability associated with potentially avoidable congenital disorders and their consequences for the children affected, their families and communities, and national health care systems, we propose priority measures that should be taken urgently to address this issue. © 2016 American Medical Association. All rights reserved.


Wani A.A.,Safdarjang Hospital and Vardhman Mahavir Medical College | Maqsood S.,St Stephens Hospital | Lala P.,Moolchand Medcity | Wani S.,Government Medical College
Journal of the Pancreas | Year: 2013

Context Annular pancreas is one of the rare congenital anomalies that can manifest itself in adulthood also. No specific guidelines and protocols exist about management of such cases. We hereby discuss our experience with two such cases along with a brief review of literature about the subject. Case reports The first patient was a male aged 27 years and presented with features of duodenal obstruction. He underwent duodenoduodenostomy. The second patient, a male aged 32 years, also presented with features of gastric outlet obstruction. He underwent Billroth type 2 reconstruction. Both patients had an uneventful recovery. Conclusion Annular pancreas in adults is a rare clinical scenario. Advancements in imaging modalities have brought to forefront an even larger number of such cases. In adults it is diagnosed mainly because of the complications that arise thereof. Gastroduodenal tuberculosis can be an important differential diagnosis in endemic areas. Treatment and operative protocols have to be individualized.


Arora S.,Maulana Azad Medical College and associated Lok Nayak Hospital | Batra S.,Safdarjang Hospital and Vardhman Mahavir Medical College | Khanna S.,University of Delhi
European Orthopaedics and Traumatology | Year: 2010

Case: A 10-year-old boy presented with disproportionate, progressive overgrowth of the right foot and lipomas over the ipsilateral knee and hip region. The patient carried the diagnosis of Proteus syndrome for many years, but careful re-evaluation of the case suggested the diagnosis of hemihyperplasia-multiple lipomatosis syndrome. Discussion: The rare sporadic disorder can be easily confused with Proteus syndrome. Differential diagnosis, approach to such patients, review of literature, and learning points related to the topic are discussed. © 2010 EFORT.


Arora N.,Safdarjang Hospital and Vardhman Mahavir Medical College | Gogna A.,Safdarjang Hospital and Vardhman Mahavir Medical College | Kumar D.,Safdarjang Hospital and Vardhman Mahavir Medical College | Puri K.,Safdarjang Hospital and Vardhman Mahavir Medical College
Tropical Doctor | Year: 2013

Symmetrical peripheral gangrene (SPG) is an extremely rare complication of malaria that has been well described in multiple case reports of Plasmodium falciparum andmixed infection.We present a case of malariawithisolatedPl. vivax infectioncomplicated by SPG. This index case is the first reported case of peripheral gangrene involving bilateral hands and feet in Pl. vivax infection in an adult.


Gupta V.,Safdarjang Hospital and Vardhman Mahavir Medical College | Gupta R.,Safdarjang Hospital and Vardhman Mahavir Medical College | Yadav S.,Safdarjang Hospital and Vardhman Mahavir Medical College
Singapore Medical Journal | Year: 2010

Neglected posterior dislocation of the elbow is a common problem in developing countries. One acceptable form of treatment is open reduction and transarticular Steinmann pin fixation. However, this leads to a stable but stiff elbow. We used an improvised external fixator after open reduction in two cases, which allowed for early mobilisation with adequate stability. This option can be considered when modern implants are not available.


PubMed | Safdarjang Hospital and Vardhman Mahavir Medical College
Type: Journal Article | Journal: Indian journal of dermatology | Year: 2010

Psoriasis is a multi-factorial skin disease with a complex pathogenesis. Various factors which have been suggested to play a key role in the pathogenesis are T cells, antigen presenting cells (APCs), keratinocytes, Langerhans cells, macrophages, natural killer cells, an array of Th1 type cytokines, certain growth factors like vascular endothelial growth factor (VEGF), keratinocyte growth factor (KGF), and others. It has been hypothesized that the disease starts with the activation of T cell by an unknown antigen, which leads to secretion of an array of cytokines by activated T cells, inflammatory cells, and keratinocytes. The characteristic lesion of psoriasis is due to the hyper-proliferation of the keratinocyte. Activated Langerhans cells migrate from skin to lymph nodes presenting the antigen to nodal nave T cells (cells that have not been activated by antigen previously). The T cells activated by non-antigen-dependent mechanism may, however, become antigen-specific memory cells that react with a cross-reactive auto-antigen such as keratin (molecular mimicry). The genetic background of the disease may be suggested from the fact that concordance rate is 63-73% in monozygotic twins, as compared to 17-20% in dizygotic twins. Several disease susceptibility loci have been suggested as predisposing factors, PSORS1-PSORS9.


PubMed | Safdarjang Hospital and Vardhman Mahavir Medical College
Type: Journal Article | Journal: Annals of medical and health sciences research | Year: 2013

To identify the socio-demographic differences between a sample of women who present for first-trimester and second-trimester abortion.To determine whether women presenting late (in the second trimester) for abortion differ socio-demographically from those presenting early (in the first trimester).Data over 4 years for women presenting for second-trimester abortion were collected from the records of Family Planning Clinic at a public tertiary level teaching hospital in India. Eighty-four cases were analysed. The case presenting for first-trimester abortion after each second-trimester abortion was included for comparison. Information was gathered concerning age, parity, educational background, employment status, educational background of the husband, family expenditure and religion. Data were statistically analysed and significance determined using logistic regression analysis.Second-trimester abortions represented 2% (84/4254) of all abortions in the study period. More women of higher age (P = 0.03) and parity (P = 0.02) and higher educational status (P = 0.04) presented for second-trimester abortion as compared to first-trimester abortion. The occupational status of the woman, husbands educational background, monthly family expenditure per person and religion did not significantly influence the time of presentation for abortion.Second-trimester abortions are associated with both increasing age and parity and higher education. This group of educated, older and multiparous women should be one of those targeted for counseling to reduce the risks associated with second trimester abortion.


PubMed | Safdarjang Hospital and Vardhman Mahavir Medical College
Type: Case Reports | Journal: Singapore medical journal | Year: 2010

Neglected posterior dislocation of the elbow is a common problem in developing countries. One acceptable form of treatment is open reduction and transarticular Steinmann pin fixation. However, this leads to a stable but stiff elbow. We used an improvised external fixator after open reduction in two cases, which allowed for early mobilisation with adequate stability. This option can be considered when modern implants are not available.

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