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Vale do Itajai University and Eurofarma Laboratorios Sa | Date: 2013-02-28

The present invention refers to a process for obtaining a standardized extract having antinociceptive, anti-inflammatory and antipyretic properties, from at least one part of a plant of genus Aleurites. Furthermore, the present invention provides a pharmaceutical composition comprising an active ingredient of a pharmaceutically efficient quantity of standardized extract from at least one part of the plant of genus Aleurites. Finally, the present invention describes a method of treatment and use of the said extract, isolated or in a pharmaceutical composition, for the prevention, control or treatment of painful, inflammatory or febrile affections.


Objective: The objective of this study was to verify the prevalence and vertical transmission rate of HIV, syphilis and hepatitis B in pregnant women in the municipality of Itajaí, state of Santa Catarina, Brazil, during the 2002-2007 period. Methods: Data were collected in a retrospective population-based longitudinal study using computerized medical records of the state and local health authorities during the 2002-2007 period for HIV, and 2004-2007 for syphilis and hepatitis B. Results: The prevalence of HIV, acute hepatitis B, chronic hepatitis B and syphilis in pregnant women was 1.7%, 0.41%, 0.46%, and 0.43%, respectively. Overall, vertical transmission of HIV was 6.28%, although it was less than 5% among women diagnosed with HIV before or during pregnancy, compared to 20% and 55% among women first diagnosed with HIV during and after delivery, respectively. Vertical transmission of syphilis was 68.89%. No trend was confirmed for the transmission rate either regarding the year of diagnosis or age group of pregnant women. Almost 44% of HIV infected pregnant women knew their HIV status before becoming pregnant; the HIV transmission rate for these women was less than 5%. No case of vertical transmission was observed for hepatitis B. Conclusions: The vertical transmission rate for HIV was within the target of the Ministry of Health when HIV diagnosis was made during pregnancy, but increased sharply when the diagnosis was made only at delivery. Vertical transmission of syphilis was much higher than expected, showing the importance of reinforcing the procedures recommended for its reduction.


Since the 1960s, little has been done to improve and simulate the use of short-duration chronic bioassays of bivalve embryos, particularly in mussels. However, these test organisms offer great advantages in relation to other groups, due to the ease of obtaining breeders in cultivation systems, in the environment and any time, and due to their high sensitivity to chemicals or contaminants. To contribute some methodological aspects, this study uses techniques to stimulate spawning or improve the obtaining of gametes for use in bioassays with the mussel Mytilus galloprovincialis. It also evaluates different criteria for determining the effect on the larvae, for estimation of EC50 and NOEC values, based on morphological analysis of developmental delay and the biometrics of the larvae. KCl proved to be a reliable inducer of spawning, with positive responses in 10 of the 12 months of the year tested. Moreover, this chemical, in association with NH4Cl, demonstrated the capacity to activate immature oocytes obtained from extirpated gonads, enabling an improvement in fertilization rates. The different criteria adopted to determine the effects on the larvae in the assays with reference toxicants (SDS and K2Cr2O7) resulted in EC50 and NOEC values without significant differences, indicating reliability in the results and freedom in the choice of criteria of effect to be adopted in the trials. © 2016 Springer Science+Business Media New York


Benitti F.B.V.,Vale do Itajai University
Computers and Education | Year: 2012

This study reviews recently published scientific literature on the use of robotics in schools, in order to: (a) identify the potential contribution of the incorporation of robotics as educational tool in schools, (b) present a synthesis of the available empirical evidence on the educational effectiveness of robotics as an educational tool in schools, and (c) define future research perspectives concerning educational robotics. After systematically searching online bibliographic databases, ten relevant articles were located and included in the study. For each article, we analyze the purpose of the study, the content to be taught with the aid of robotics, the type of robot used, the research method used, and the sample characteristics (sample size, age range of students and/or level of education) and the results observed. The articles reviewed suggest that educational robotics usually acts as an element that enhances learning, however, this is not always the case, as there are studies that have reported situations in which there was no improvement in learning. The outcomes of the literature review are discussed in terms of their implications for future research, and can provide useful guidance for educators, practitioners and researchers in the area. © 2011 Published by Elsevier Ltd. All rights reserved.


Rossetto A.L.,Vale do Itajai University | Cruz R.C.B.,Vale do Itajai University
Anais Brasileiros de Dermatologia | Year: 2012

The authors report a case of Tinea nigra in an 8-year-old child, male, from Itajaí, SC, Brazil, with lesions of the macular hyperchromic type, unique, asymptomatic, localized in the right palmar area. The lesion was treated with the topical antifungal butenafine, with remission of symptoms and without recurrence at follow-up for two years. © 2012 by Anais Brasileiros de Dermatologia.


Zimmermann A.C.,Vale do Itajai University | Mecabo A.,Vale do Itajai University | Fagundes T.,Vale do Itajai University | Rodrigues C.A.,Vale do Itajai University
Journal of Hazardous Materials | Year: 2010

In the present investigation, Fe-chitosan crosslinked is used as adsorbent for the removal of chromium from aqueous solutions. The influence of pH, temperature and other ions was evaluated. pH 2.0 was found to be the optimum pH for adsorption of Cr(VI) onto Ch-Fe. Coordination of unsaturated sites for the iron(III) complex of polymer were considered to be the adsorption sites for Cr(VI) species, the predominant species being HCrO4-. The Langmuir and Langmuir-Freundlich adsorption isotherm models were applied to describe the isotherm parameter for Cr(VI) adsorption. The results indicate that the Langmuir-Freundlich adsorption model and maximum adsorption capacity was calculated as 295mg/g at 25°C, with pH 4.7. Cr(VI) uptake on the adsorbent decreased from 295mg/g at 25°C to 209mg/g at 65°C. Rate constants as a function of temperature were evaluated with the help of a proposed second order kinetic model. The other coexisting ions, nitrate, chlorides and sulphate influenced Cr(VI) adsorption. © 2010 Elsevier B.V.


Schwarz R.,Vale do Itajai University | Perez J.A.A.,Vale do Itajai University
Fisheries Research | Year: 2010

Statoliths of 689 Illex argentinus specimens collected by national and foreign trawlers in Brazilian waters were analyzed. Catches occurred between 2001 and 2008, from 23° to 32° S and at depths of 80-730. m. Exponential, Power, Gompertz and Schnute models were fitted to size-at-age data and the logistic model was used for maturity modeling. Fitting procedures used the maximum log-likelihood and Akaike criteria for identification of best models. Total age estimates ranged between 56 and 320 days for squid between 35 and 376. mm mantle lengths. Gompertz and Schnute models, which suggest the positive acceleration of growth in the early stages of ontogeny followed by a decrease in the second phase, provided the best fit to the size-at-age dispersion in this study. The inflection point in the maturity curve was 137 days for males and 143 days for females. The age range for post-spawning squid was 116-250 (average 187) days for males and 133-280 (average 201) days for females showing a life cycle close to six months. None of the examined individuals reached one year of age. The wide range of sizes-at-age implied that catches of I. argentinus off southern Brazil probably include mixed micro-cohorts and different population units. © 2010 Elsevier B.V.


Schroeder R.,Vale do Itajai University | Perez J.A.A.,Vale do Itajai University
Fisheries Research | Year: 2010

Intra-specific growth variability of the gladius of Illex argentinus was analyzed based on 870 specimens collected off Brazil from 2001 to 2002, and divided into two depth groups (shelf break and slope spawners) between 23-32°S and depths of 45-722. m. Squid samples included adult individuals caught throughout the year and were pooled by sex and season (spring, summer, autumn and winter spawners). Growth increments measured directly on the gladius plate were smoothed by a low-pass filter and used to reconstruct size-specific growth trajectories for males and females separately. The reconstructed trajectories of the proposed spawning groups were found to be significantly different. Squid captured during the winter exhibited faster growth followed by summer, spring and autumn spawners. During winter, shelf-break spawners presented lower growth rates when compared to slope spawners. Seasonal and bathymetric growth variability was discussed in the light of biological production patterns off southeastern and southern Brazilian coast. Higher growth rates observed in the trajectories reconstructed for winter spawners could not be supported by these local patterns and it is suggested that they reflect an early-life in more productive areas, such as the Patagonian shelf. © 2010 Elsevier B.V.


Debrassi A.,Vale do Itajai University | Rodrigues C.A.,Vale do Itajai University
Clean - Soil, Air, Water | Year: 2011

The adsorption of three cationic dyes (rhodamine B, RB; crystal violet, CV; and malachite green, MG) onto termite feces, a low-cost adsorbent, was investigated. The adsorbent was characterized by IR spectroscopy, point of zero charge measurement, and the Boehm titration method. The adsorption follows the pseudo-second-order kinetic model and the Langmuir-Freundlich isotherm with maximum adsorption capacities of 95.53mgg -1 (RB), 75.71mgg -1 (CV), and 44.78mgg -1 (MG). The study of thermodynamics showed that the adsorption is a spontaneous and endothermic process. This works suggest that termite feces can be used as a new low-cost adsorbent for cationic dye removal. © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.


Rossetto A.L.,Vale do Itajai University | Cruz R.C.B.,Vale do Itajai University
Anais Brasileiros de Dermatologia | Year: 2012

The authors report a case (in Itajai, Santa Catarina State, Brazil) of tinea nigra in a 4-year-old female child which spontaneously healed. We discuss the clinical and epidemiological aspects of the mycosis and this rare case of spontaneous healing. © 2012 by Anais Brasileiros de Dermatologia.

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