Deerfield, IL, United States
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Poteet W.M.,Vail Systems | Cauthen H.K.,Vail Systems | Kappler N.,TBR Construction and Engineering | Kappler L.G.,TBR Construction and Engineering | And 4 more authors.
Proceedings of SPIE - The International Society for Optical Engineering | Year: 2012

The KMTNet telescope Project, sponsored by The Korea Astronomy and Space Science Institute (KASI), is fabricating three wide-field equatorial mount telescopes of 1.6 meter aperture to conduct continuous observations of the Galactic bulge region to search for extra-solar planets. Southern latitude sites secured for these telescopes are SAAO (South Africa), CTIO (Chile), and SSO (Australia). A prime-focus configuration, along with a four-lens corrector achieves the 2.8 degree diagonal FOV. The basic mechanical design utilizes a scaled-up version of the successful 2MASS Telescopes built by the authors in the late 1990's. Scaling up of components has presented challenges requiring several iterations of the detailed mechanical analysis as well as the optical analysis due to interaction with mounting assemblies for the optical components. A flexure-style focus mechanism, driven by three precision actuators, moves the entire headring assembly and provides real-time focus capability, and active primary mirror cooling is implemented for the Zerodur primary. KMTNet engineering specifications are met with the current design, which uses Comsoft's Legacy PCTCS for control. A complete operational telescope and enclosure are scheduled for installation in Tucson, AZ prior to shipping the first hardware to CTIO in order to verify tracking, optical characteristics at various attitudes, and overall observatory functionality. The cameras, being fabricated by The Ohio State University Department of Astronomy, Imaging Sciences Laboratory (ISL), are proceeding in parallel with the telescope fabrication, and that interface is now fixed. Specifics of the mechanical and optical design are presented, along with the current fabrication progress and testing protocols. © 2012 SPIE.


Li H.,Vail Systems | Hou H.,Vail Systems | Sucheta A.,Vail Systems | Williams B.B.,Vail Systems | And 5 more authors.
Advances in Experimental Medicine and Biology | Year: 2010

EPR oximetry using implantable resonators allows measurements at much deeper sites than are possible with surface resonators (> 80 vs. 10 mm) and achieves greater sensitivity at any depth. We report here the development of an improved technique that enables us to obtain the information from multiple sites and at a variety of depths. The measurements from the various sites are resolved using a simple magnetic field gradient. In the rat brain multiprobe implanted resonators measured pO2 at several sites simultaneously for over 6 months under normoxic, hypoxic, and hyperoxic conditions. This technique also facilitates measurements in moving parts of the animal such as the heart, because the orientation of the paramagnetic material relative to the sensing loop is not altered by the motion. The measured response is fast, enabling measurements in real time of physiological and pathological changes such as experimental cardiac ischemia in the mouse heart. The technique also is quite useful for following changes in tumor pO2, including applications with simultaneous measurements in tumors and adjacent normal tissues. © Springer Science+Business Media, LLC 2010.


Williams B.B.,Vail Systems | Khan N.,Vail Systems | Zaki B.,Vail Systems | Hartford A.,Vail Systems | And 2 more authors.
Advances in Experimental Medicine and Biology | Year: 2010

Electron paramagnetic resonance (EPR) oximetry can be used to provide direct absolute measurements of pO2 in living tissue using India ink as anO2 reporter. In vivo measurements aremade using low frequency (1.2 GHz) EPR spectroscopy and surface loop resonators, which enable measurements to be made at superficial sites through a non-invasive (after placing the ink in the tissues) and repeatable measurement procedure. Ongoing EPR oximetry studies in human subjects include measurement of subcutaneous pO2 in the feet of healthy volunteers to develop procedures that could be used in the treatment of peripheral vascular disease and oximetry in tumors during courses of radiation and chemotherapy, to follow pO2 so oxygen-dependent therapies can be optimized. In each case, we aim to provide quantitative measurements of tissue pO2 which will aid physicians in the characterization of disease status and the effects of therapeutic measures, so that treatments can be applied with optimal effectiveness by taking into account the oxygendependent aspects of the therapy. The overall goal is to enhance clinical outcomes. Oximetry measurements of subcutaneous tissue on dorsal and plantar foot surfaces have been made in 9 volunteers, with measurements ongoing for each and the longest set of measurements carried out successfully over the last 5 years. Tumor oximetry measurements have been performed in tumor tissues of 10 patients during courses of radiation and chemotherapy. Tumor types include melanoma, basal cell, soft tissue sarcoma, and lymphoma, and measurement sites have ranged from the feet to the scalp. These studies demonstrate the feasibility of EPR oximetry in a clinical setting and the potential for more widespread use in the treatment of these and other oxygen-dependent diseases. © Springer Science+Business Media, LLC 2010.


Hou H.,Vail Systems | Hou H.,Dartmouth Hitchcock Medical Center | Mupparaju S.P.,Vail Systems | Lariviere J.P.,Vail Systems | And 8 more authors.
Radiation Research | Year: 2013

Tumor hypoxia impedes the outcome of radiotherapy. As the extent of hypoxia in solid tumors varies during the course of radiotherapy, methods that can provide repeated assessment of tumor pO2 such as EPR oximetry may enhance the efficacy of radiotherapy by scheduling irradiations when the tumors are oxygenated. The repeated measurements of tumor pO2 may also identify responders, and thereby facilitate the design of better treatment plans for nonresponding tumors. We have investigated the temporal changes in the ectopic 9L and C6 glioma pO2 irradiated with single radiation doses less than 10 Gy by EPR oximetry. The 9L and C6 tumors were hypoxic with pO2 of approximately 5-9 mmHg. The pO2 of C6 tumors increased significantly with irradiation of 4.8-9.3 Gy. However, no change in the 9L tumor pO2 was observed. The irradiation of the oxygenated C6 tumors with a second dose of 4.8 Gy resulted in a significant delay in growth compared to hypoxic and 2 Gy × 5 treatment groups. The C6 tumors with an increase in pO2 of greater than 50% from the baseline of irradiation with 4.8 Gy (responders) had a significant tumor growth delay compared to nonresponders. These results indicate that the ectopic 9L and C6 tumors responded differently to radiotherapy. We propose that the repeated measurement of the oxygen levels in the tumors during radiotherapy can be used to identify responders and to design tumor oxygen guided treatment plans to improve the outcome. © 2013 by Radiation Research Society.


Trademark
Whistle Phone Llc and Vail Systems | Date: 2011-06-14

Computer software for use in computer telephony, enabling voice communication services via computers and mobile devices, and enhanced telephone activities such as call notification and call forwarding. Telecommunications services in the nature of providing communications via mobile telephones, smart phones, mobile internet devices and computers; providing voice communication services via telecommunications networks, wireless communication networks, and the internet; providing electronic network conferencing services and teleconferencing services, and providing call forwarding services; providing access to telecommunications networks via wireless communications and computer networks; providing voice over internet protocol (VOIP) services.


Trademark
Vail Systems | Date: 2011-06-16

Computer and Software Products; namely computer software for the contact center industry which provides analytic and real-time user scripting based on events derived from both audio and data streams generated throughout various human-assisted customer interactions.


Patent
Level 3 Communications and Vail Systems | Date: 2015-11-16

Implementations of the present disclosure involve systems and methods for federating communications between a first network that transmits and receives messages formatted in a first format and a second network that transmits and receives messages formatted in a second format. The systems and methods are configured to receive a message from the first network formatted in the first format. The system then converts the message into a unified format that may be sent to the second network. After receiving the message in the unified format, the message may then be converted into the format of the second network and sent on the second network like any other message on the second network.


Trademark
Vail Systems | Date: 2011-10-19

Computer software for analyzing voice interactions, namely computer software for analyzing the systematics of multi-party voice interactions such as turn-taking, adjacency pairing, back channeling, listening and other paralinguistic cues to provide real-time computer assistance in the form of analysis, scripting and personalized post-interaction coaching within various human-assisted support environments.


Trademark
Vail Systems | Date: 2016-05-06

Downloadable computer software for use in computer telephony, enabling voice communication services via computers and mobile devices, and enhanced telephone activities such as call notification and call forwarding. A cloud-based Application Programming Interface (API) that provides access to telecommunications functionality enabling software engineers to integrate telecommunication features, namely, sending or receiving voice calls or messages, into their software applications.


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