Uttrakhand Technical University

Dehradun, India

Uttrakhand Technical University

Dehradun, India

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Ahmad Y.,Uttrakhand Technical University
Der Pharma Chemica | Year: 2012

A reliable and sensitive isocratic stability indicating RP-HPLC method has been developed and validated for assay of Ezetimibe in tablets and for determination of content uniformity. An isocratic separation of Ezetimibe was achieved on Zorbax SB C18 (250mm × 4.6mm), 5 μm particle size columns with a flow rate of 1 ml/min and using a UV detector to monitor the eluate at 232nm. The mobile phase consisted of 0.02N ortho phosphoric acid: acetonitrile (20:80 v/v).The drug was subjected to oxidation, hydrolysis, photolysis and thermal degradation. All degradation products in an overall analytical run time of approximately 6 min with the parent compound Ezetimibe eluting at approximately 3.5 min. Response was a linear function of drug concentration in the range of 1-10 μg/ml (r 2 = 0.9993). Accuracy (recovery) was between 100.80. Degradation products resulting from the stress studies did not interfere with the detection of Ezetimibe and the assay is thus stability-indicating.

Goel A.,University of the Humanities | Goel A.,Uttrakhand Technical University | Taj G.,University of the Humanities | Pandey D.,University of the Humanities | And 2 more authors.
Genomics, Proteomics and Bioinformatics | Year: 2011

The mechanism of calcium uptake, translocation and accumulation in Poaceae has not yet been fully understood. To address this issue, we conducted genome-wide comparative in silico analysis of the calcium (Ca 2+) transporter gene family of two crop species, rice and sorghum. Gene annotation, identification of upstream cis-acting elements, phylogenetic tree construction and syntenic mapping of the gene family were performed using several bioinformatics tools. A total of 31 Ca 2+ transporters, distributed on 9 out of 12 chromosomes, were predicted from rice genome, while 28 Ca 2+ transporters predicted from sorghum are distributed on all the chromosomes except chromosome 10 (Chr 10). Interestingly, most of the genes on Chr 1 and Chr 3 show an inverse syntenic relationship between rice and sorghum. Multiple sequence alignment and motif analysis of these transporter proteins revealed high conservation between the two species. Phylogenetic tree could very well identify the subclasses of channels, ATPases and exchangers among the gene family. The in silico cis-regulatory element analysis suggested diverse functions associated with light, stress and hormone responsiveness as well as endosperm- and meristem-specific gene expression. Further experiments are warranted to validate the in silico analysis of the predicted transporter gene family and elucidate the functions of Ca 2+ transporters in various biological processes. © 2011 Beijing Genomics Institute.

Bahadur P.,Amity University | Jain A.,Indian Institute of Technology Kanpur | Chauhan D.S.,Uttrakhand Technical University
International Conference and Workshop on Emerging Trends in Technology 2011, ICWET 2011 - Conference Proceedings | Year: 2011

Machine Translation is one of the most challenging tasks in natural language processing. Statistical machine translation (SMT) looks into the translation of natural language as a machine learning problem. Since, the advent of globalization need for cross language translator has increased. English has emerged as most popular language on World Wide Web. The developing regions still strive to access the information in local languages. Translation of English into local languages can make information flow easier. This paper is on undergoing research for design and development of a cross language system from English to Sanskrit to make the same convenient. Copyright © 2011 ACM.

Bishnoi L.C.,Uttrakhand Technical University | Jat D.S.,University of Namibia
Advances in Intelligent Systems and Computing | Year: 2016

This paper proposes a Novel Cross-layer Mechanism (NCLM) for Improving H.264/AVC Video Transmissions over IEEE 802.11n wireless network. According to the network traffic loads and the importance of the video data, the proposed mechanism dynamically selects the suitable access categories (AC) instead of predefined AC. This proposed novel cross-layer mechanism gives the information about the importance of video packets to the MAC layer. Information about the network traffic load is available from the queue length of all access categories. During this research, we analyzed the performance of NCLM in both light and heavy load over IEEE 802.11n wireless networks. In this research, the performance of video traffic measured by average: Throughput, PSNR, VQM, and SSIM. Simulation results of this research demonstrate that the performance of proposed mechanism was higher in comparison to the results derived from IEEE 802.11n EDCA, CLOT, DACMM, IPB-Frame AMM, and Static Mapping algorithm. © Springer Science+Business Media Singapore 2016.

Bishnoi L.C.,Uttrakhand Technical University | Singh D.,Polytechnic of Namibia | Mishra S.,Kumaon Engineering College
ACM International Conference Proceeding Series | Year: 2014

The Scalable Video Coding (SVC) compression technique is extension of H.264/AVC which is developed by Joint Video Team of the ITU-T VCEG and the ISO/EC MPEG. SVC enables scalability support and capable to adapt bitrate with lower temporal or spatial resolutions for wireless channel bandwidth those varying with time. In this paper, we proposed a cross-layer mechanism, which includes video packet prioritization and Quality of Services (QoS) mapping, for the transmitting SVC video over the IEEE 802.1 1n wireless networks without aggregation. The proposed mechanism delivery enables interaction with Medium Access Control (MAC) layer, providing controlling of different Access Classifications (ACs) for video packets. Our purposed Traffic Queue Controlling Cross-layer Mechanism (TQCCLM) performs with the SVC packet prioritization at the MAC layer according to Temporal Identification (TId) Quality Identification (QId) values of incoming video SliceData and access queue length. Simulation results shows that the proposed mechanism improves SVC video quality when compared to IEEE 802.1 1n EDCA default mapping method.

Yadav S.,Uttrakhand Technical University | Mishra S.,Uttrakhand Technical University | Yadav R.,Uttrakhand Technical University
Advances in Intelligent Systems and Computing | Year: 2014

In this paper we examine the performance of two types of Overlay networks i.e. Peer-to-Peer (P2P) & Content Delivery Network (CDN) media streaming using Multiple Description Coding (MDC). In both the approaches many servers simultaneously serve one requesting client with complementary descriptions. This approach improves reliability and decreases the data rate a server has to provide. We have implemented both approaches in the ns-2 network simulator. The experimental results indicate that the performance of Multiple Description Codingbased media streaming in case of P2P network is better than CDN. © Springer India 2014.

Singh S.K.,Uttrakhand Technical University | Prasad A.,Vishveshwarya Group of Institutions | Singh P.K.,Madan Mohan Malaviya University of Technology | Singh R.K.,Uttrakhand Technical University
Proceedings of the 2014 International Conference on Issues and Challenges in Intelligent Computing Techniques, ICICT 2014 | Year: 2014

In this paper, we consider the problems and benefits of developing the infrastructure needed to handle the timing requirements of a real-time industrial control application and the processing of image streams. In particular, this paper explores various application scenarios which can benefit from a real-time control system integrated with images. An experimental test set-up is used to verify the NDDS's performance for Distributed Real Time-Image Processing System. Tests results show that RTPS middleware (and NDDS specifically) is suitable for soft and firm timelines requirements for distributed real time database systems. © 2014 IEEE.

Mishra S.,Kumaon Engineering College | Chauhan D.S.,Uttrakhand Technical University
International Journal of Mobile Computing and Multimedia Communications | Year: 2011

In this paper, the authors discuss the emergence of new technologies related to the topic of the high-speed packet data access in wireless networks. The authors propose an algorithm for MIMO systems that optimizes the number of the transmit antennas according to the user's QoS. Scheduling performance under two types of traffic modes is also discussed: one is voice or web-browsing and the other is for data transfer and streaming data. © 2011, IGI Global.

Goel A.,Govind Ballabh Pant University of Agriculture & Technology | Goel A.,Uttrakhand Technical University | Gaur V.S.,Govind Ballabh Pant University of Agriculture & Technology | Arora S.,Govind Ballabh Pant University of Agriculture & Technology | And 2 more authors.
OMICS A Journal of Integrative Biology | Year: 2012

The calcium (Ca2+) transporters, like Ca2+ channels, Ca2+ ATPases, and Ca2+ exchangers, are instrumental for signaling and transport. However, the mechanism by which they orchestrate the accumulation of Ca2+ in grain filling has not yet been investigated. Hence the present study was designed to identify the potential calcium transporter genes that may be responsible for the spatial accumulation of calcium during grain filling. In silico expression analyses were performed to identify Ca2+ transporters that predominantly express during the different developmental stages of Oryza sativa. A total of 13 unique calcium transporters (7 from massively parallel signature sequencing [MPSS] data analysis, and 9 from microarray analysis) were identified. Analysis of variance (ANOVA) revealed differential expression of the transporters across tissues, and principal component analysis (PCA) exhibited their seed-specific distinctive expression profile. Interestingly, Ca2+ exchanger genes are highly expressed in the initial stages, whereas some Ca2+ ATPase genes are highly expressed throughout seed development. Furthermore, analysis of the cis-elements located in the promoter region of the subset of 13 genes suggested that Dof proteins play essential roles in regulating the expression of Ca 2+ transporter genes during rice seed development. Based on these results, we developed a hypothetical model explaining the transport and tissue specific distribution of calcium in developing cereal seeds. The model may be extrapolated to understand the mechanism behind the exceptionally high level of calcium accumulation seen in grains like finger millet. © 2012 Mary Ann Liebert, Inc.

Gupta S.K.,Uttrakhand Technical University | Govil K.,Uttrakhand Technical University | Agarwal A.,JP Institute of Engineering and Technology
Proceedings - 2015 International Conference on Computational Intelligence and Communication Networks, CICN 2015 | Year: 2015

A Mobile Ad hoc Network (MANET) is a wireless network that supports the mobile nodes to communicate with each other without using fixed infrastructure. There are many issues with MANET such as security, power consumption, storage, processing power. For Life of network is directly proportional battery power in mobile nodes. The present research paper presents an algorithm that reduces the power consumption by using binary conversion technique in addressing mode. Mobile node looses their battery power at different rate at different mode such as data transmission mode, reception mode, idle mode, power sever mode. The given algorithm maintains the mobile node in lower power consumption stage. © 2015 IEEE.

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