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Prague, Czech Republic

Jirku V.,Ustav Biotechnologie | Lovecka P.,Ustav biochemie a mikrobiologie | Cejkova A.,Ustav Biotechnologie | Mackova M.,Ustav biochemie a mikrobiologie | And 2 more authors.
Chemicke Listy

This review provides information on the bioremediation function of microorganisms and natural additives like humic substances biosurfactants. In this respect, phytoremediation combines a remediative function of plants with a possible complementary function of root-colonizing microflora. Source

Karabin M.,Ustav Biotechnologie | Hudcova T.,Ustav Biotechnologie | Jelinek L.,Ustav Biotechnologie | Dostalek P.,Ustav Biotechnologie
Chemicke Listy

In recent years, a growing interest in health-promoting effects of hop constituents has been observesd. Xanthohumol is a hop prenylated chalcone, which shows a wide range of biological activities such as antioxidant, anticancerogenic, antimicrobial and estrogenic. Most interesting findings obtained with xanthohumol and other prenylated hop flavonoids in preclinical and clinical studies are summarized. The review is primarily focused on the effects on human health. Biosynthesis of prenylated flavonoids in plants and their biotransformations in humans are also mentioned. Source

Fribert P.,Ustav Biotechnologie | Paulova L.,Ustav Biotechnologie | Patakova P.,Ustav Biotechnologie | Rychtera M.,Ustav Biotechnologie | Melzoch K.,Ustav Biotechnologie
Chemicke Listy

Although distillation is a predominant technique used for separation of liquid biofuels (bioethanol and biobutanol), other methods, which can be integrated in fermentation can be exploited as an alternative. Application of these processes (gas stripping, pervaporation, adsorption, liquid extraction, pertraction and reverse osmosis) together with their main features and advantages are discussed. By exploitation of these methods lower energy demand and enhanced productivity of fermentation can be achieved and some problems such as product toxicity in acetonebutanol- ethanol fermentation are eliminated. Source

Prior to its use as feedstock in ethanol production, lignocellulose biomass must be decomposed and hydrolysed. In mild physicochemical pretreatment a wide range of degradation products such as organic acids, furan derivatives or phenolic compounds are formed, which can act as inhibitors. The inhibitors can affect the activity of cellulolytic enzymes and the metabolism of microbial cells and thus decrease the conversion of cellulose to fermentable sugars and the efficiency of ethanol production. The effect of individual compounds on the commercially available enzymes, yeasts and bacterial strains employed in ethanol production together with the inhibition mechanism is discussed. Several strategies to minimize the inhibitory effect such as physical, chemical or biological detoxification of hydrolysates or the use of strains tolerant to inhibitors are discussed. Source

Jelinek L.,Ustav Biotechnologie | Karabin M.,Ustav Biotechnologie | Kincl T.,Ustav Biotechnologie | Hudcova T.,Ustav Biotechnologie | And 2 more authors.
Chemicke Listy

Xanthohumol is the main prenylated flavonoid from hop plants with proven positive effects on human health. Currently, the only source of this substance in human diet is beer, where the content of xanthohumol rarely exceeds 0.1 mg l-1. The present article gives a comprehensive overview of current trends in the isolation of xanthohumol from hop cones and of production of beer with an increased content of this substance. Source

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