Ustav biotechnologie

Prague, Czech Republic

Ustav biotechnologie

Prague, Czech Republic
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Kvasnickova E.,Ustav biotechnologie | Paldrychova M.,Ustav biotechnologie | Matatkova O.,Ustav biotechnologie | Masak J.,Ustav biotechnologie
Chemicke Listy | Year: 2016

The formation and development of bacterial as well as yeast or filamentous fungi biofilms, which is connected with dangerous or even fatal human infections, represents a relatively new and poorly studied problem in current medicine. The understanding of the processes running in biofilms of pathogenic microorganisms and finding of new possibilities of the biofilm prevention or eradication and also the regulation of biofilm resistance development is necessary for proposing advanced treatment procedures for wide range of illnesses. © 2016, Czech Society of Chemical Engineering. All rights reserved.


Karabin M.,Ustav Biotechnologie | Hudcova T.,Ustav Biotechnologie | Jelinek L.,Ustav Biotechnologie | Dostalek P.,Ustav Biotechnologie
Chemicke Listy | Year: 2012

In recent years, a growing interest in health-promoting effects of hop constituents has been observesd. Xanthohumol is a hop prenylated chalcone, which shows a wide range of biological activities such as antioxidant, anticancerogenic, antimicrobial and estrogenic. Most interesting findings obtained with xanthohumol and other prenylated hop flavonoids in preclinical and clinical studies are summarized. The review is primarily focused on the effects on human health. Biosynthesis of prenylated flavonoids in plants and their biotransformations in humans are also mentioned.


Jirku V.,Ustav biotechnologie | Lovecka P.,Ustav biochemie a mikrobiologie | Cejkova A.,Ustav biotechnologie | Mackova M.,Ustav biochemie a mikrobiologie | And 2 more authors.
Chemicke Listy | Year: 2012

This review provides information on the bioremediation function of microorganisms and natural additives like humic substances biosurfactants. In this respect, phytoremediation combines a remediative function of plants with a possible complementary function of root-colonizing microflora.


Prior to its use as feedstock in ethanol production, lignocellulose biomass must be decomposed and hydrolysed. In mild physicochemical pretreatment a wide range of degradation products such as organic acids, furan derivatives or phenolic compounds are formed, which can act as inhibitors. The inhibitors can affect the activity of cellulolytic enzymes and the metabolism of microbial cells and thus decrease the conversion of cellulose to fermentable sugars and the efficiency of ethanol production. The effect of individual compounds on the commercially available enzymes, yeasts and bacterial strains employed in ethanol production together with the inhibition mechanism is discussed. Several strategies to minimize the inhibitory effect such as physical, chemical or biological detoxification of hydrolysates or the use of strains tolerant to inhibitors are discussed.


Jelinek L.,Ustav biotechnologie | Karabin M.,Ustav biotechnologie | Kincl T.,Ustav biotechnologie | Hudcova T.,Ustav biotechnologie | And 2 more authors.
Chemicke Listy | Year: 2013

Xanthohumol is the main prenylated flavonoid from hop plants with proven positive effects on human health. Currently, the only source of this substance in human diet is beer, where the content of xanthohumol rarely exceeds 0.1 mg l-1. The present article gives a comprehensive overview of current trends in the isolation of xanthohumol from hop cones and of production of beer with an increased content of this substance.


Fribert P.,Ustav biotechnologie | Paulova L.,Ustav biotechnologie | Patakova P.,Ustav biotechnologie | Rychtera M.,Ustav biotechnologie | Melzoch K.,Ustav biotechnologie
Chemicke Listy | Year: 2013

Although distillation is a predominant technique used for separation of liquid biofuels (bioethanol and biobutanol), other methods, which can be integrated in fermentation can be exploited as an alternative. Application of these processes (gas stripping, pervaporation, adsorption, liquid extraction, pertraction and reverse osmosis) together with their main features and advantages are discussed. By exploitation of these methods lower energy demand and enhanced productivity of fermentation can be achieved and some problems such as product toxicity in acetonebutanol- ethanol fermentation are eliminated.

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