Sokoto, Nigeria

Usmanu Danfodio University

www.udusok.edu.ng
Sokoto, Nigeria

Usmanu Danfodiyo University is one of the initial twelve federal universities in Nigeria founded in 1975. It is in the ancient city of Sokoto.The school is named after Usman Dan Fodio, the founder of the Sokoto Caliphate. Wikipedia.

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Ashiru R.M.,Kano University of Science and Technology | Garba Y.,Bayero University | Maigandi S.A.,Usmanu Danfodio University | Muhammad I.R.,Bayero University
Iranian Journal of Applied Animal Science | Year: 2017

A feeding trial was conducted to assess the effect of inclusion of ensiled sugarcane waste (ESCW) with poultry litter on performance of Yankasa rams in a completely randomized design (CRD) for twelve weeks (84 days). Sugarcane waste was mixed with poultry litter in 3:1 and ensiled for 21 days. The ESCW was used as partial replacement in complete diet. Sixteen Yankasa rams (mean body weigh 28.94 ± 5.77 kg and aged 12 to 18 months) were allotted to the four groups on the basis of body weights into control group without ESCW (CG) or control diets as treatment groups (TGs) partially replaced with ESCW at 15% (TG1), 30% (TG2) or 45% (TG3). Diets were offered ad libitum, along with clean drinking water and min-eral salt lick at will. The results showed no significant (P > 0.05) differences in the treatment means of all the growth parameters evaluated, values recorded for TG3 (45%) were numerically higher in final live weight, weight gain and average daily gains (ADG). Significant (P < 0.05) differences were recorded in dry matter and ash intakes while the dry matter, crude fibre and ash apparent digestibility differed significantly (P < 0.05) among the CG and TGs. In conclusion, performances of Yankasa rams with 45% inclusion of ESCW were comparable to CG and its usage is therefore recommended as alternative choice during the lean periods based on the observed nutritional facts. © 2010 Islamic Azad Univerty, Rasht Branch, Rasht, Iran.


PubMed | Ahmadu Bello University, Nigeria Institute of Leather and Science Technology and Usmanu Danfodio University
Type: Journal Article | Journal: Pharmacognosy research | Year: 2015

Medicinal plants remain one of the largest reservoirs of new bioactive compounds. In this study, a new prenylated benzo-lactone (4, 6-dihydroxy-5-methoxy-3-(1, 2, 3, 4, 5-pentahydroxypentyl)-2-benzofuran-1(3H)-one) was isolated from the acetone extracts of the rhizome of Cissus cornifolia. The antimicrobial activity of the compound was evaluated against some microorganisms including Staphylococcus aureus, Salmonella typhi, and Candida albicans.The acetone extracts of the rhizome of C. cornifolia was separated and purified by various chromatographic techniques. The structure of the isolated compound was characterized by analysis of spectral data including one and two-dimensional nuclear magnetic resonance.The isolated compound was characterized as (4, 6-dihydroxy-5-methoxy-3-(1, 2, 3, 4, 5-pentahydroxypentyl)-2-benzofuran-1(3H)-one), it showed activity against 6 out of 10 tested clinical isolates of some microorganisms including S. aureus, S. typhi, and C. albicans. The inhibition zones ranged between 17 mm and 25 mm. The inhibition zones observed compare favorably with the positive control used.The compound could serve as a lead for the development of more potent antimicrobial agent. To the best of our knowledge, this is the first report of the isolation and characterization as well as antimicrobial screening of the compound.


Egua M.O.,Usmanu Danfodio University | Etuk E.U.,Usmanu Danfodio University | Bello S.O.,Usmanu Danfodio University | Hassan S.W.,Usmanu Danfodio University
Journal of Pharmacognosy and Phytotherapy | Year: 2014

The Corchorus olitorius seeds were pulverized (grounded) to powder. The powdered seed (200 g) was extracted with 500 ml of ethanol (99.9%) within a period of 24 h and the procedure repeated 3 times using the same powdered extract. Extraction and fractionation were carried out with some modification in the choice of primary solvent (water) and partitioning (separating) solvents (hexane, chloroform, ethyl acetate and butanol). The fractions obtained (hexane, chloroform, ethyl acetate, saturated butanol and last remaining aqueous) were tested for antidiabetic and phytochemical properties. Two doses were employed while testing in diabetic rats, 500 and 250 mg/kg body weight. Diabetes was induced by a single intraperitoneal injection of 150 mg/kg body wt alloxan (Sigma) in saline. Animals with a blood glucose level ≥ 150 mg/dl were considered diabetics. All the fractions had some bioactivity in alloxan induced diabetic rats. The activity being better with the 500 mg doses than the 250 mg. Statistical significance (p < 0.05) in bioactivity (blood sugar change) was only seen with the aqueous fraction (1 h post treatment), chloroform fraction (1, 3 and 4 h post treatment) and the ethyl acetate fraction (2 and 3 h post treatment). The action of the seed extract can be attributed to phytochemical content of the extract. Of these flavanoids, alkaloids, saponins have been reported to have hypoglycaemic effect. © 2014 Academic Journals.


PubMed | Obafemi Awolowo University, National Orthopaedic Hospital, Usmanu Danfodio University and The Surgical Center
Type: Journal Article | Journal: Annals of maxillofacial surgery | Year: 2016

This report describes the multidisciplinary management of a 35-year-old female sickle-cell anemia patient who had unilateral bony ankylosis of the left temporomandibular joint secondary to septic arthritis. She was managed by a team comprising of maxillofacial surgeons, anesthetists, otorhinolaryngologist, and hematologist. Unilateral left interpositional arthroplasty and ipsilateral coronoidectomy through a postrami approach were done and followed by aggressive jaw physiotherapy in the postsurgical period. No perioperative morbidity was encountered. Mouth opening of 3.5 cm was achieved and maintained 7 months after surgery. Challenges and rationale for the use of a multidisciplinary team approach in treatment of such cases were discussed.


PubMed | Novartis, Usmanu Danfodio University, Bill and Melinda Gates Foundation and University of Siena
Type: Journal Article | Journal: Human vaccines & immunotherapeutics | Year: 2016

Nigeria has made tremendous strides towards eliminating polio and has been free of wild polio virus (WPV) for more than a year as of August 2015. However, sustained focus towards getting rid of all types of poliovirus by improving population immunity and enhancing disease surveillance will be needed to ensure it sustains the polio-free status. We reviewed the pertinent literature including published and unpublished, official reports and working documents of the Global Polio Eradication Initiative (GPEI) partners as well as other concerned organizations. The literature were selected based on the following criteria: published in English Language, published after year 2000, relevant content and conformance to the theme of the review and these were sorted accordingly. The challenges facing the Polio Eradication Initiative (PEI) in Nigeria were found to fall into 3 broad categories viz failure to vaccinate, failure of the Oral Polio Vaccine (OPV) and epidemiology of the virus. Failure to vaccinate resulted from insecurity, heterogeneous political support, programmatic limitation in implementation of vaccination campaigns, poor performance of vaccination teams in persistently poor performing Local Government areas and sporadic vaccine refusals in Northern Nigeria. Sub optimal effectiveness of OPV in some settings as well as the rare occurrence of VDPVs associated with OPV type 2 in areas of low immunization coverage were also found to be key issues. Some of the innovations which helped to manage the threats to the PEI include a strong government accountability frame work, change from type 2 containing OPV to bi valent OPVs for supplementary immunization activities (SIA), enhancing environmental surveillance in key states (Sokoto, Kano and Borno) along with an overall improvement in SIA quality. There has been an improvement in coverage of routine immunization and vaccination campaigns, which has resulted in Nigeria being removed from the list of endemic countries following an absence of new cases for an entire year as of September 2015. However, the last mile remains to be crossed and there is need to further improve and sustain the momentum to complete the journey toward polio elimination.


Dahiru T.,Ahmadu Bello University | Oche O.M.,Usmanu Danfodio University
Pan African Medical Journal | Year: 2015

Introduction: utilization of antenatal care, institutional delivery and postnatal care services in Nigeria are poor even by african average.Methods: we analysed the 2013 Nigeria DHS to determine factors associated with utilization of these health MCH indicators by employing both bivariate and multivariate logistic regressions.Results: overall, 54% of women had at least four ANC visits, 37% delivered in health facility and 29% of new born had postnatal care within two of births. Factors that consistently predict the utilization of the three MCH services are maternal and husband's level education, place of residence, wealth level and parity. Antenatal care strongly predicts both health facility delivery (OR=2.16, 95%CI: 1.99-2.34) and postnatal care utilization (OR=4.67, 95%CI: 3.95-5.54); while health facility delivery equally predicting postnatal care (OR=2.84, 95%CI: 2.20-2.80).Conclusion: improving utilization of these three MCH indicators will require targeting women in the rural areas and those with low level of education as well as creating demand for health facility delivery. Improving ANC use by making it available and accessible will have a multiplier effect of improving facility delivery which will lead to improved postnatal care utilization. © Tukur Dahiru et al.


Febrile convulsions (FC) are a common paediatric problem worldwide. Between 1 and 4% of children will have a febrile convulsion with about 4% of cases arising before the age of six months. Although FC is benign and does not cause death, brain damage or learning disorders, it is quite frightening to observers and parents who witness an episode of FC, would think the child is going to die. This was a quasi-experimental study (a pre and post-test interventional, one group), aimed at assessing the impact of health education on knowledge and home management of febrile convulsion amongst mothers in a rural community in North Western Nigeria. A one in three samples of fifty mothers that met the eligibility criteria where selected using systematic random sampling. Structured interviewer administered questionnaire with close and open-ended questions was administered to obtain data at pre- and post intervention. The ages of the mothers ranged from 18-47 with a mean age of 33 ± 7.14 years. The perceived causes of febrile convulsion included fever (28%), witch craft (80%) with majority (98%) of the mothers administering traditional medications. Proportion of study subjects with adequate knowledge of febrile convulsion at baseline and post intervention were 4% (mean knowledge score of 35.3 ± 9.48) and 96.0% (mean knowledge score of 77.69 ± 10.75) respectively (P < 0.0001). Although inadequate knowledge and inappropriate home practices about FC were rampant in the study community, using community members to teach and sensitize the mothers on FC improved their knowledge base significantly. The use of effective educational intervention programmes and parental support groups will go a long way in reducing the incidence of FC among children in our communities.


Oche O.M.,Usmanu Danfodio University | Ben Onankpa O.,Usmanu Danfodio University
Pan African Medical Journal | Year: 2013

Introduction: Febrile convulsions (FC) are a common paediatric problem worldwide. Between 1 and 4% of children will have a febrile convulsion with about 4% of cases arising before the age of six months. Although FC is benign and does not cause death, brain damage or learning disorders, it is quite frightening to observers and parents who witness an episode of FC, would think the child is going to die. Methods: This was a quasi-experimental study (a pre and post-test interventional, one group), aimed at assessing the impact of health education on knowledge and home management of febrile convulsion amongst mothers in a rural community in North Western Nigeria. A one in three samples of fifty mothers that met the eligibility criteria where selected using systematic random sampling. Structured interviewer administered questionnaire with close and open-ended questions was administered to obtain data at pre- and post intervention. Results: The ages of the mothers ranged from 18-47 with a mean age of 33 ± 7.14years. The perceived causes of febrile convulsion included fever (28%), witch craft (80%) with majority (98%) of the mothers administering traditional medications. Proportion of study subjects with adequate knowledge of febrile convulsion at baseline and post intervention were 4% (mean knowledge score of 35.3± 9.48) and 96.0% (mean knowledge score of 77.69 ± 10.75) respectively (P<0.0001). A total of 16 and 97% of the mothers had appropriate home practices with regards to FC at base line and post intervention respectively (P<0.0001). Conclusion: Although inadequate knowledge and inappropriate home practices about FC were rampant in the study community, using community members to teach and sensitize the mothers on FC improved their knowledge base significantly. The use of effective educational intervention programmes and parental support groups will go a long way in reducing the incidence of FC among children in our communities. © Oche Mansur Oche et al.


PubMed | Obafemi Awolowo University and Usmanu Danfodio University
Type: Journal Article | Journal: Nigerian journal of surgery : official publication of the Nigerian Surgical Research Society | Year: 2016

The most common sequelae after surgical removal of mandibular third molar are pain, trismus, swelling, and dysphagia. However, these symptoms can also signal the onset of surgical site infection and alveoli osteitis. The aim of this study was to evaluate the efficacy of prophylactic amoxicillin/clavulanic acid and levofloxacin and preemptive therapy of amoxicillin/clavulanic acid in the reduction of postinflammatory complications, surgical site infection, and alveolar osteitis following the third molar surgery.A total of 135 patients were randomized into three equal groups: Group A (preemptive therapy of amoxicillin/clavulanic acid) with preoperative dose of 875/125 mg amoxicillin/clavulanic acid followed by 500/125 mg amoxicillin/clavulanic acid 12 hourly for 5 days, Group B (amoxicillin/clavulanic acid prophylaxis) with a single preoperative dose of amoxicillin/clavulanic acid 875/125 mg tablets, and Group C (levofloxacin prophylaxis) with a single preoperative dose of levofloxacin 1000 mg tablets. All patients had ostectomy using surgical handpiece and burs and received same analgesics (tabs ibuprofen 400 mg 8 hourly for 3 days).No case of surgical site infection or alveoli osteitis was recorded in the study groups. There were no statistically significant differences between the treatment groups with regard to pain, mouth opening, postoperative facial dimension, and body temperature.Amoxicillin/clavulanic acid as a single preoperative bolus should be adequate for the prevention of postoperative wound infection and alveoli osteitis following the third molar extraction as there is no need for an extension of the antibiotic. Moreover, levofloxacin can be utilized as prophylaxis in patients undergoing mandibular third molar extraction if such patients are allergic to penicillins.


PubMed | Ahmadu Bello University and Usmanu Danfodio University
Type: | Journal: The Pan African medical journal | Year: 2015

Utilization of antenatal care, institutional delivery and postnatal care services in Nigeria are poor even by african average.We analysed the 2013 Nigeria DHS to determine factors associated with utilization of these health MCH indicators by employing both bivariate and multivariate logistic regressions.Overall, 54% of women had at least four ANC visits, 37% delivered in health facility and 29% of new born had postnatal care within two of births. Factors that consistently predict the utilization of the three MCH services are maternal and husbands level education, place of residence, wealth level and parity. Antenatal care strongly predicts both health facility delivery (OR = 2.16, 95%CI: 1.99-2.34) and postnatal care utilization (OR = 4.67, 95%CI: 3.95-5.54); while health facility delivery equally predicting postnatal care (OR = 2.84, 95%CI: 2.20-2.80).Improving utilization of these three MCH indicators will require targeting women in the rural areas and those with low level of education as well as creating demand for health facility delivery. Improving ANC use by making it available and accessible will have a multiplier effect of improving facility delivery which will lead to improved postnatal care utilization.

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