Urbino, Italy

Urbino University

www.uniurb.it
Urbino, Italy

The University of Urbino "Carlo Bo" is an Italian university located in Urbino, a walled hill-town in the region of Marche, located in the north-eastern part of central Italy. The university was founded in 1506 and, in the 1920s, gained recognition as an “Independent University” with a charter which made state aid possible though not mandatory. Once fully recognized as an Independent University, student numbers gradually increased as more facilities were opened.During the 1960s/70s, the University succeeded in buying up quite a number of derelict palaces in the old center which have since been restored and used as faculty and department buildings. While the student body and faculties gradually increased and developed over time it was under the long and presidency of Senator for Life Carlo Bo that the University enjoyed unprecedented growth in size and prestige, prompting the former president of the European Community Commission, Roy Jenkins, to state that “the University of Urbino is an incisive presence in contemporary thought, contributing in original ways to the cultural and intellectual life of Europe”. This was also the period where architect Giancarlo De Carlo designed and built the University Halls of Residence, which can accommodate 1500 students.Today, the University of Urbino is a State University. It numbers 10 faculties and currently has about 20,000 students, many of whom are from overseas. The university has no central campus as such, and instead occupies numerous buildings throughout the town and in the surrounding countryside. The main accommodation blocks are situated a short distance from the town. The University of Urbino has traditionally given precedence to studies in the humanities, and is especially renowned for its Italian-language courses. Wikipedia.

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Grant
Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: SSH.2012.2.2-1 | Award Amount: 8.20M | Year: 2013

The central hypothesis of this project is that socio-economic, socio-demographic, ethnic and cultural diversity can positively affect social cohesion, economic performance and social mobility of individuals and groups. A better social cohesion, higher economic performance and increased chances for social mobility will make European cities more liveable and more competitive. In this period of long-term economic downturn (or sometimes even crisis) and increasing competition from countries elsewhere in the world (e.g. China, India), it is important to find out how and under which circumstances Europeans urban diversity can be turned into social and economic advantages. Many current urban policies lack a positive view on urban diversity, because they generally focus on the negative aspects of diversity, such as intolerance, racism, discrimination and insecurity. New policies, instruments and governance arrangements are needed, and sometimes they already exist. We have to find out how they have become successful and how they can be implemented elsewhere. When we acknowledge the hyper-diversity of our urban societies, we also have to acknowledge that these societies cannot flourish from standard or general approaches aiming at, for example, economic growth or better housing or more liveable neighbourhoods. Increasingly, more diverse, more tailored arrangements are needed, arrangements that have an eye for hyper-diverse cities and communities. As a result of the project, new and innovative policy instruments and governance arrangements will be suggested that (a) recognise urban diversity as a positive aspect; (b) increase interaction and communication between the diversity of groups in urban society; and (c) increase participation to satisfy the needs of the communities. The project thus aims at finding out how urban diversity influences three core issues: social cohesion, economic performance and social mobility and how governance arrangements help to strengthen this.


Grant
Agency: European Commission | Branch: FP7 | Program: CSA-CA | Phase: ENV.2013.6.5-2 | Award Amount: 1.20M | Year: 2013

SEFIRA has the objective of creating a European coordination of transdisciplinary scientific and socio-economic resources in order to support the review and implementation of air quality legislation by the European Commission (EC) led by DG Environment. The EC has now given increased attention to the socio-economic dimension of air quality policies in order to improve their effectiveness and acceptability. SEFIRA will coordinate some of the best scientific and socio-economic resources and will review air quality policies and legislation at the interface between environmental, economic and social sciences in order to achieve a deeper understanding of these complex issues. Individual behaviours and choices will be analysed in a socio-economic context ranging from the local to the European level. The main fields involved in the action will be atmospheric sciences, environmental and legal sociology, anthropology, geography and economics. The integration of disciplines, the relationship with the most relevant stakeholders and an effective coordination between the SEFIRA consortium and other European projects in the same field will be a priority. The project strategy will support the development of a new European appraisal of problems and resources in the field, will deploy a pilot survey and a test of policy implementation by innovative models of individual choices analysis and ecosystem services valuation. Stakeholders will be involved from the beginning of the project in a process of dialogue and cooperative problem solving in order to ensure relevance and robustness as the work progresses from local to European level.


Grant
Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: SSH.2012.1.3-2 | Award Amount: 3.09M | Year: 2013

The INSPIRES project aims to contribute to resilient and inclusive labour markets in Europe. It comparatively assesses the resilience and inclusiveness of labour markets in European countries, it identifies innovative policies that have contributed to resilience and inclusiveness and it analyzes strategies of policy learning that facilitate the development and transfer of these innovations within and across European nation states. In order to do so, it analyzes in-depth the evolution of labour markets policies, employment policies and social policies. Moreover, it qualitatively and quantitatively assesses the labour market position of vulnerable groups from 2000 onwards. INSPIRES covers eleven countries from all European welfare traditions: Mediterranean, Eastern-European, Anglo-Saxon, Scandinavian and the continental regimes. The consortium consists of a multidisciplinary team of leading European scholars that focus on the labour market, employment issues and social policies. The INSPIRES project aims to accumulate practice-oriented knowledge on the factors that positively and negatively affect resilience and inclusiveness. It seeks to explain differences within and between countries, and within and between the labour market positions of different vulnerable groups on the labour market. INSPIRES intends to isolate the impact of national policies from the structural demographic, social and economic characteristics on labour market resilience. Building upon this analysis, it tries to identify processes of policy learning and innovation that occur in the interactions between policy makers, politicians, non-profit organizations, trade unions, business associations and other stakeholders at the European, national and regional level. The outcomes of INSPIRES contribute to facilitating policy learning and innovation processes across territorial and sectoral boundaries and to the creation of inclusive and resilient labour markets in European countries.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: PHC-14-2015 | Award Amount: 5.87M | Year: 2016

The main objective of the project is to provide a treatment of the neurological symptoms of patients with Ataxia Telangiectasia (AT), a rare progressively disabling and life-shortening genetic disease for which no therapy is currently available. To achieve this, a pivotal Phase III study will be conducted, to allow regulatory filing to obtain market authorization in EU and USA by 2019. EryDex is an innovative product, developed by EryDel, used to administer dexamethasone sodium phosphate by ex-vivo encapsulation in autologous erythrocytes, which are infused into the patient. EryDex provides long-term delivery of low doses of dexamethasone without the typical steroid side effects and has reached a successful Phase II trial conducted in AT patients. The phase III trial will be an international, multi-center, 1 year, randomized, prospective, double-blind, placebo-controlled, designed to assess the effect of 2 dose ranges of EryDex, administered monthly by IV infusion, on neurological symptoms of AT patients. The protocol of the trial and the regulatory path to registration has already been agreed upon with EMA and FDA. An international patient registry will also be set with the aim of establishing and maintaining a comprehensive clinical database of patients with AT and closely related conditions, enabling the monitoring of AT epidemiology, the development of an evidence-based natural history of the condition, identification of biomarkers as well as development of clinical guidelines. The AT NEST, the first scale to assess symptoms specific to AT patients, coordinated by the AT centre at the Johns Hopkins University, will be tested in the study and if validated will represent the 1st scale assessing chief areas of impairment specific to AT. In parallel to the clinical trial, investigations into the molecular mechanisms of action of EryDex will be performed with the objective to provide the validation of a new biomarker predictive of treatment efficacy.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: ICT-10-2015 | Award Amount: 1.54M | Year: 2016

Road networks are the largest publicly owned assets and they play a fundamental role in socio-economic development and competitiveness. At the same time, roads have huge environmental impacts and maintenance costs. Passenger cars account for 73.7% of total intra-EU passenger transport, with an average car occupancy rate well below 2 passengers per car. The resulting traffic accounts for about 12% of CO2 emissions. Delayed maintenance impairs road safety and increases cost of intervention, vehicle operating costs, and emissions. The CROWD4ROADS project combines trip sharing and crowd sensing initiatives to harness collective intelligence to contribute to the solution of the sustainability issues of road passenger transport, by increasing the car occupancy rate and by engaging drivers and passengers in road monitoring. BlaBlaCar (http://blablacar.com/) is the largest trusted ride sharing community worldwide, with more than 10.000.000 members in 14 countries, while SmartRoadSense (http://smartroadsense.it/) is a crowd sensing system which makes use of the accelerometers of car-mounted smartphones to estimate the roughness of the road surface. The CROWD4ROADS platform establishes a synergistic relationship between BlaBlaCar and SmartRoadSense, exploiting the network effect which is inherent in both the initiatives, to provide a sizeable impact in terms of car occupancy rate, road monitoring, and end-user engagement in road maintenance and transport sustainability. Scalability issues will be addressed during the project both from a technical and from a social point of view. The approach will be validated on representative large scale pilots, involving more than 1 million people and covering more than 1 million km of roads. Impacts will be measures in terms of road coverage, car occupancy rates, and open data volume.


Patent
The Regents Of The University Of California, University of Parma, Urbino University and Italian Institute of Technology | Date: 2014-02-18

The present invention provides methods of making and using peripherally restricted inhibitors of fatty acid amide hydrolase (FAAH). The present invention provides compounds and compositions that suppress FAAH activity and increases anandamide levels outside the central nervous system (CNS). The present invention also sets forth methods for inhibiting FAAH as well as methods for treating conditions such as, but not limited to, pain, inflammation, immune disorders, dermatitis, mucositis, the over reactivity of peripheral sensory neurons, neurodermatitis, and an overactive bladder. Accordingly, the invention also provides compounds, methods, and pharmaceutical compositions for treating conditions in which the selective inhibition of peripheral FAAH (as opposed to CNS FAAH) would be of benefit.


Patent
The Regents Of The University Of California, Urbino University, Italian Institute of Technology and University of Parma | Date: 2015-09-14

Described herein are compounds and pharmaceutical compositions which inhibit N-acylethanolamine acid amidase (NAAA). Described herein are methods for synthesizing the compounds set forth herein and methods for formulating these compounds as pharmaceutical compositions which include these compounds. Also described herein are methods of inhibiting NAAA in order to sustain the levels of palmitoylethanolamide (PEA) and other N-acylethanolamines (NAE) that are substrates for NAAA, in conditions characterized by reduced concentrations of NAE. Also, described here are methods of treating and ameliorating pain, inflammation, inflammatory diseases, and other disorders in which modulation of fatty acid ethanolamides is clinically or therapeutically relevant or in which decreased levels of NAE are associated with the disorder.


Patent
Italian Institute of Technology, University of Parma and Urbino University | Date: 2016-04-25

The present invention provides compounds and pharmaceutical compositions for inhibiting N-acylethanolamine acid amidase (NAAA). Inhibition of NAAA is contemplated as a method to sustain the levels of palmitoylethanolamide (PEA) and oleylethanolamide (OEA), two substrates of NAAA, in conditions characterized by reduced concentrations of PEA and OEA. The invention also provides methods for treating inflammatory diseases and pain, and other disorders in which decreased levels of PEA and OEA are associated with the disorder.


Patent
The Regents Of The University Of California, Urbino University and University of Parma | Date: 2016-03-16

Compounds and pharmaceutical compositions are contemplated that inhibit N-acyl-ethanolamine-hydrolyzing acid amidase (NAAA) to so increase the concentration of the substrate of NAAA, palmitoylethanolamide (PEA). NAAA inhibition is contemplated to be effective to alleviate conditions associated with a reduced concentration of PEA. Among other uses, various NAAA inhibitors are especially contemplated as therapeutic agents in the treatment of inflammatory diseases.


Grant
Agency: European Commission | Branch: FP7 | Program: MC-IIF | Phase: FP7-PEOPLE-2013-IIF | Award Amount: 241.57K | Year: 2014

A new generation of high-precision gravity sensors such as torsion pendulums and atom interferometers, and future concepts for kilometer-scale gravitational-wave (GW) detectors searching for ripples in spacetime from colliding and exploding stars, will make it possible to study gravity perturbations in the frequency range 0.1Hz to 10Hz. These include terrestrial gravity perturbations that are of interest to Earth scientists, but that are considered as noise contribution in GW detectors. The applicant wants to carry out a detailed study of terrestrial gravity perturbations in the above given frequency range. The analysis will include gravity perturbations from fault rupture, and from seismic waves that are predicted to live on interfaces deep inside Earth such as the core-mantel boundary. Numerical simulations will be used to generate full gravity time series based on dynamical models of the sources and of the propagation of the seismic disturbance. This research will provide a completely new approach to understand the first minute of earthquakes. Furthermore, results from the fault-rupture analysis will be used to determine the impact that gravity sensors could have in earthquake-early warning systems. The project will also investigate terrestrial gravity noise in GW detectors with focus on the poorly understood atmospheric perturbations. Infrasound fields, convection and turbulent air flow are all expected to generate significant gravity noise in GW detectors. The goal is to create improved models for atmospheric perturbations partially based on numerical simulations. The results will be used to develop strategies to mitigate this type of gravity noise in GW detectors. The outcome of this research will have great impact on future developments of ground-based GW detection.

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