Puebla de Zaragoza, Mexico
Puebla de Zaragoza, Mexico

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Torres G.A.,UPAEP University | Benitez V.H.,University of Sonora
ACM International Conference Proceeding Series | Year: 2016

In this paper the classification of finger gesture using multichannel surface electromyography (sEMG) signals is proposed. Three types of hand gestures were applied to be identified, when participants holding spherical objects. A specific finger position is evaluated while the hand grasps a specific geometrical object, whose shape is considered as a way to introduce a parameter variation. Hand natural motions are collected by placing electrodes on five muscles on the forearm of six healthy subjects who are fastenings spheres into a controlled environment. A feature vector approach in time domain (TD) is given as input to a linear discriminant analysis (LDA) module used as statistical pattern classifier. We show that it is possible to categorize each motion, that is, TD feature based provide an effective representation for classification, indicating the membership of myoelectric signals (MES) collected to a finger positions class. These results will be useful for human hand motion analysis and has potential applications especially in robotic hand or prosthetic hand control and human-computer interaction (HCI). © 2016 ACM.


Ruiz Y.,Public Health and Senior Researcher | Guilamo-Ramos V.,New York University | McCarthy K.,New York University | Munoz-Laboy M.A.,Temple University | De Lourdes Rosas Lopez M.,UPAEP University
American Journal of Public Health | Year: 2014

Migration and population movement are increasingly viewed as important factors associated with HIV transmission risk. With growing awareness of the potential impact of migration on HIV transmission, several perspectives have emerged that posit differing dynamics of risk. We considered available data on the role of migration on HIV transmission among Mexicanmigrants inNew York City and Puebla, Mexico. Specifically, we examined 3 distinct models of migratory dynamics of HIV transmission-namely, the structural model, the local contextual model, and the interplay model. In doing so, we reframed current public health perspectives on the role of migration on HIV transmission.


Casco S.,UPAEP University | Soto-Vega E.,Research Center Oncologica
Hormones and Cancer | Year: 2016

Long-term childhood cancer survivors are at great risk of developing late adverse effects after treatment, such as, reduced growth, obesity, decreased fertility, high blood pressure, cardiovascular diseases, impaired glucose, another form of cancer, among others organ dysfunctions, some of them are part of the metabolic syndrome. Metabolic syndrome and cancer connection is still not entirely understood, but there are some notions about it. Metabolic alterations produced during childhood cancer are more likely determined by treatments like radiotherapy, chemotherapy, glucocorticoids therapy, and surgery. Cancer treatment is associated to vascular alterations, hormone deficiencies, changes in insulin sensitivity, lipid metabolism, and inflammatory mediators. Obesity has been considered a crucial component in metabolic syndrome; obesity risk factors during childhood cancer include cranial radiation, female gender, and exposure to glucocorticoids such as dexamethasone. In addition, local radiotherapy or surgery may cause endocrine deficiencies, depends on the directly damage of endocrine organs. Patients who received some types of cancer treatment should be evaluated periodically to early diagnostic metabolic disorders associated to antineoplastic therapy. © 2016, Springer Science+Business Media New York.


Castro-Manzano J.M.,UPAEP University | Castro-Manzano J.M.,National Autonomous University of Mexico
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2013

Intentional reasoning is a form of logical reasoning with a temporal-intentional and defeasible nature. By covering conditions of material and formal adequacy we describe a defeasible logic of intention to support the thesis that intentional reasoning is bona fide reasoning. © 2013 Springer-Verlag.


Gomez-Almaguer D.,Autonomous University of Nuevo León | Herrera-Rojas M.A.,Autonomous University of Nuevo León | Jaime-Perez J.C.,Autonomous University of Nuevo León | Gomez-De Leon A.,Autonomous University of Nuevo León | And 6 more authors.
Blood | Year: 2014

Immune thrombocytopenia (ITP) results from platelet destruction and production suppression. Eltrombopag belongs to a new class of thrombopoietin-mimetic drugs that raise platelet counts in ITP patients. We performed a single-arm study to assess the response to a single course of dexamethasone (40 mg by mouth, days 1-4) in combination with eltrombopag (50 mg,days5-32) in 12 adults with newly diagnosed ITP in anoutpatient setting. Median follow-up was 12.5 months. After therapy (day 33), 100% of patients achieved at least ≥30 × 109/L platelets. Four patients relapsed. Complete response at 6 months (platelets ≥100 × 10 9/L) was achieved in 50% of patients and response at 6 months (platelets ≥30 <100 × 109/L) was achieved in another 25%; relapse-free survival was 66.7% at 12 months (median response duration of 8.3 months). In conclusion, eltrombopag/dexamethasone is a feasible frontline therapy for ITP. This trial is registered at www.clinicaltrials.gov as NCT01652599. © 2014 by The American Society of Hematology.


Ruiz-Arguelles A.,UPAEP University
Hematology | Year: 2012

Minimal residual disease refers to the tumour cells that are still present in a given patient after completion of a therapeutic scheme. The demonstration and quantification of residual neoplastic cells has a crucial impact in clinical decision making, for it might prompt continuation of treatment, while the absence of such cells might serve as evidence to withdraw therapy. Therefore, both sensitivity and specificity of the methods used to unravel residual neoplastic cells must be highly reliable and robust. Flow cytometry has been widely used for this purpose, and its clinical performance depends mainly on the criteria of interpretation, rather than in the technique by itself; molecular biology techniques have proved to be highly sensitive and specific but unfortunately they cannot be used in all patients or in all types of leukemia. Finally, the development of donor cell leukemia in transplanted patients, might mimic residual disease and add more confusion to an already controversial issue. These topics are discussed in this paper. © W. S. Maney & Son Ltd 2012.


Garces-Eisele J.,UPAEP University
Hematology | Year: 2012

The prognostic significance of minimal residual disease (MRD) has been demonstrated for a variety of hematologic malignancies. PCR based assays are among the most important methods for identifying MRD. They are aimed at detecting genetic abnormalities of residual leukemic cells with high specificity and sensitivity and represent an important diagnostic tool to assess the quality of therapeutic response, for clinical risk assessment, and for clinical management. In the present review technical aspects of different MRD detection methods are discussed which depend on the available targets regularly present in the respective leukemia type and subtype. As such fusion transcripts, gene mutations, and clonal rearrangements of antigen-receptor genes may be available for detection. Emphasis is given on discussing benefits and limitations of MRD detection and quantification in CML, AML and ALL. © W. S. Maney & Son Ltd 2012.


Castro-Manzano J.M.,UPAEP University
Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) | Year: 2013

We present the initial results of a series of studies around the concept of computational political philosophy. We show a computational interpretation of three classical models of political philosophy that justify three different forms of government by implementing some experiments in order to provide evidence to answer the question of which political philosophy proposes a more plausible form of government. We focus in the relation commitment vis-à-vis earnings and we observe that although some political philosophies would justify highly united (communal) or highly competitive (liberal) communities, they would not necessarily imply societies with a reasonable level of welfare. © 2013 Springer-Verlag.


Olivares-Benitez E.,UPAEP University | Rios-Mercado R.Z.,Autonomous University of Nuevo León | Gonzalez-Velarde J.L.,Monterrey Institute of Technology
International Journal of Production Economics | Year: 2013

This paper addresses a supply chain design problem based on a two-echelon single-product system. In the first echelon the plants transport the product to distribution centers. In the second echelon the distribution centers transport the product to the customers. Several transportation channels are available between nodes in each echelon, with different transportation costs and times. The decision variables are the opening of distribution centers from a discrete set, the selection of the transportation channels, and the flow between facilities. The problem is modeled as a bi-objective mixed-integer program. The cost objective aggregates the opening costs and the transportation costs. The time objective considers the longest transportation time from the plants to the customers. An implementation of the classic epsilon-constraint method was used to generate true efficient sets for small instances of the problem, and approximate efficient sets for larger instances. A metaheuristic algorithm was developed to solve the problem, as the major contribution of this work. The metaheuristic algorithm combines principles of greedy functions, Scatter Search, Path Relinking and Mathematical Programming. The large instances were solved with the metaheuristic algorithm and a comparison was made in time and quality with the epsilon-constraint based algorithm. The results were favorable to the metaheuristic algorithm for large instances of the problem. © 2013 Elsevier B.V.


Castro-Manzano J.M.,UPAEP University
CEUR Workshop Proceedings | Year: 2012

Intentional reasoning is a form of defeasible reasoning whose metalogical properties have not been studied completely both logically or philosophically. Our contribution in this paper is the study of such metalogical properties in order to show that intentional reasoning has the right to be called logical reasoning since it behaves as a logic, strictly speaking, as a non-monotonic logic.

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