UOC di Oncologia Medica

Cosenza, Italy

UOC di Oncologia Medica

Cosenza, Italy
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Gori S.,U.O.C. Oncologia Medica | Pinto C.,Oncologia Medica | Caminiti C.,UO Ricerca e Innovazione | Aprile G.,SOC Oncologia | And 17 more authors.
Tumori | Year: 2016

Cancer care involves many ethical issues. The need for more patient-centered healthcare together with the improved empowerment of every person diagnosed with cancer have been transposed by the Italian Association of Medical Oncology (AIOM) and eventually translated in the Ragusa statement. This position paper describes the philosophy that lies beneath this document and its fundamental principles. © 2016 Wichtig Publishing.


PubMed | Presidenza Salute Donna, Farmindustria, Direzione Generale Instituto Giano, Ospedale I.D.I. and 14 more.
Type: Journal Article | Journal: Tumori | Year: 2016

Cancer care involves many ethical issues. The need for more patient-centered healthcare together with the improved empowerment of every person diagnosed with cancer have been transposed by the Italian Association of Medical Oncology (AIOM) and eventually translated in the Ragusa statement. This position paper describes the philosophy that lies beneath this document and its fundamental principles.


Palazzo S.,UOC di Oncologia Medica | Filice A.,UOC di Oncologia Medica | Mastroianni C.,UOC di Oncologia Medica | Biamonte R.,UOC di Oncologia Medica | And 10 more authors.
Recenti Progressi in Medicina | Year: 2016

Clinical decision making in oncology is based so far on the evidence of efficacy from high-quality clinical research. Data collection and analysis from experimental studies provide valuable insight into response rates and progression-free or overall survival. Data processing generates valuable information for medical professionals involved in cancer patient care, enabling them to make objective and unbiased choices. The increased attention of many scientific associations toward a more rational resource consumption in clinical decision making is mirrored in the Choosing Wisely campaign against the overuse or misuse of exams and procedures of little or no benefit for the patient. This cultural movement has been actively promoting care solutions based on the concept of "value". As a result, the value-based decision-making process for cancer care should not be dissociated from economic sustainability and from ethics of the affordability, also given the growing average cost of the most recent cancer drugs. In support of this orientation, the National Comprehensive Cancer Network (NCCN) has developed innovative and "complex" guidelines based on values, defined as "evidence blocks", with the aim of assisting the medical community in making overall sustainable choices.


Cioffi P.,Servizio di Farmacia | Di Giandomenico F.,U.O.C. di Oncologia Medica | Marotta V.,University of Camerino | Petragnani G.,Servizio di Farmacia | And 2 more authors.
Giornale Italiano di Farmacia Clinica | Year: 2010

Fluorouracil (5-FU) is a commonly used chemotherapeutic agent for a variety of tumor types, intravenously. Although capecitabine and tegafut, 5-FU oral prodrugs, induce rarely paralytic ileus, this particular intestinal toxicity has never been attributed to 5-FU. Paralytic ileus (or adynamic ileus) refers to a lack of passage of intestinal contents due to disturbances of normal intestinal motility, in absence of mechanical obstruction. A lot of anticancer drug, target-therapy drugs too, are the most common causes of this toxitity. The clinical case in local Lanciano Hospital we present is of a patient diagnosed as having colon cancer and he was admitted with paralytic ileus following adjuvant treatment with 5-FU (Mayo-clinic schedule). Naranjo, Jones algoritms suggest a direct casual relationship. Our case, to our knowledge, represents the first published report of this particular intestinal toxicity of 5-FU. Paralytic ileus is probably a rare complication of 5-FU and its oral prodrugs, but the oncologist should take it into careful consideration, because of his possible seriousness and because a correct management of early signs of abdominal distension (with nasogastric suction, i.v. infusion of fluids and electrolytes, rectal tube) can avoid a unnecessary surgical operation.


PubMed | UOC di Oncologia Medica, UOC di Farmacia and UOS Qualita e Accreditamento.
Type: Journal Article | Journal: Recenti progressi in medicina | Year: 2016

Clinical decision making in oncology is based so far on the evidence of efficacy from high-quality clinical research. Data collection and analysis from experimental studies provide valuable insight into response rates and progression-free or overall survival. Data processing generates valuable information for medical professionals involved in cancer patient care, enabling them to make objective and unbiased choices. The increased attention of many scientific associations toward a more rational resource consumption in clinical decision making is mirrored in the Choosing Wisely campaign against the overuse or misuse of exams and procedures of little or no benefit for the patient. This cultural movement has been actively promoting care solutions based on the concept of value. As a result, the value-based decision-making process for cancer care should not be dissociated from economic sustainability and from ethics of the affordability, also given the growing average cost of the most recent cancer drugs. In support of this orientation, the National Comprehensive Cancer Network (NCCN) has developed innovative and complex guidelines based on values, defined as evidence blocks, with the aim of assisting the medical community in making overall sustainable choices.

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