Serdarevic N.,University of Sarajevo |
Zunic L.,University of Zenica
Acta Informatica Medica | Year: 2012
Background: Cyclosporine has been shown effective drug in suppressing acute rejection in recipients of allograft organ transplants. Methods: The cyclosporine concentration of 96 blood samples was determined using CMIA (chemiluminesecent microparticle immnoassay) Architect i 2000 and FPIA (fluorescence polarization immunoassay) AxSYM Abbott diagnostic. All patients have transplantation of kidneys and were hospitalized at Department of Nephrology at the Clinical center of University of Sarajevo. The reference serum range of cyclosporine for kidney organ transplantation for maintenance lies between 50 and 150 ng/mL. The quality control, precision and accurancy of Architect i 2000 were assessed. Results: The quality control was done using quality control serums for low (= 91 ng/mL), medium (= 328 ng/mL) and high (= 829 ng/ mL). We have used commercial BIORAD controls and got reproducibility CV 5.83 % to 13 % for Architect i 2000. It was established that the main difference between Architect i 2000 and AxSYM and it was statistically significant for P < 0.05 according to Student t-test. Correlation coefficient was r = 0.903. Conclusion: The CMIA Architect assay has significant reduced cyclosporine metabolite interference relative to other immunoassay and is a convenient and sensitive automated method to measure cyclosporine in whole blood. © Avicena 2012.
Influence of chemical bonding of chlorides with aluminates in cement hidratation process on corrosion steel bars in concrete [Uticaj hemijskog vezivanja hlorida za aluminate u procesu hidratacije cementa na koroziju čelične armature u betonu]
Bikic F.H.,University of Zenica
Hemijska Industrija | Year: 2010
The presence of chlorides in concrete is a permanent subject of research because they cause corrosion of steel bars. Chlorides added to the concrete during preparation, as accelerators of the bonding of cement minerals process, enter into reaction with aluminates, creating a phase known as chloroaluminate hydrates. In everyday conditions the product of chemical bonding between chlorides and aluminates is usually monochloridealuminate C3A• CaCl2•Hx, better known as Friedel's salt. In this paper, the influence of chemical bonding of chlorides with aluminates during the process of cement hydration on corrosion of steel bars in concrete was investigated. The process of chlorides bonding with aluminates yielding monochloride aluminate is monitored by XRD analyses. It was found that the amount of chlorides bonding with aluminates increases with an increase of temperature, and as a result, reduces the amount of "free" chlorides in concrete. Potentiodynamic measurements have shown that increase in temperature of the heat treatment of working electrodes by chlorides leads to a reduction of steel bars corrosion as a result of either the increase of the monochloride-aluminate content or the decrease of free chlorides amount. Chlorides bound in chloroaluminate hydrates do not cause activation of steel bars corrosion in concrete. It was also proven that the increase of free chlorides concentration in the concrete leads to intensification of steel bars corrosion. This additionally approves that free chlorides are only the activators of process of steel bars corrosion in the concrete.
Oruc M.,University of Zenica
Medicinski arhiv | Year: 2012
Appendicitis is one of the most common diseases that require urgent surgical intervention. Due to its position, the inflamed appendix can cause many complications in abdominal cavity. Most of these complications are based on the anatomical position of the appendix. According to world literature over 65% of the anatomical positions of appendix is retrocaecal position, followed paracaecal and then the other positions of the appendix in different percentages. The main goal of this research is to shown that anatomical retrocaecal position of the appendix can lead to prolonged hospitalization and more often occurrence of appendicitis complications. The research is based on patients who had appendectomy during 2009 at the Cantonal Hospital Zenica and General Hospital Tesanj. The study included approximately 400 respondents and the method of research was of retrospective, descriptive and analytical type. According to the results of this research we can conclude that in our country is not devoted enough attention to the anatomic position of the appendix and that we are not using enough diagnostic methods such as ultrasound and CT in determining the anatomic position to help determine the course of the disease. Retrocaecal appendix position according to the obtained data from this study did not cause many complications in classical appendectomy but this can be attributed to insufficient observation of the anatomical position of the appendix.
Tukovic Z.,University of Zagreb |
Ivankovic A.,University College Dublin |
Karac A.,University of Zenica
International Journal for Numerical Methods in Engineering | Year: 2013
Correct calculation of stresses at the interface of bonded or otherwise joined materials plays a significant role in many applications. It is therefore important that traction at the material interface is calculated as accurately as possible. This paper describes procedures that can be employed to achieve this goal by using centre-based finite-volume method. Total traction at the interface is calculated by decomposing it into normal and tangential components, both being calculated at each side of the interface, and applying the continuity assumption. The way in which the traction approximation is achieved depends on calculation of tangential gradient of displacement at the interface. To this end, three different methods are proposed and validated against problems with known solutions. It was shown that all methods can be successfully used to simulate problems with multi-material domains, with the procedure based on finite area method being most accurate. © 2012 John Wiley & Sons, Ltd.
Tandir S.,University of Zenica
Medicinski arhiv | Year: 2011
Reporting on infectious diseases is one of the most important measures for controlling the infectious diseases. In Bosnia and Herzegovina is in the implementation an archaic system of reporting, older than 20 years, which is incorporated into the partially reformed health system. The aim of this study is to determine and analyze the quality of keeping records of communicable diseases and quality of data obtained. It also sought to identify weaknesses in the system that contributes to poor reporting and poor data quality. The study was retrospective-prospective, descriptive and analytical. Data were collected during June 2010 from all health facilities of Zenica-Doboj Canton. The data are collected from regular reports from medical institutions, received reports on contagious diseases, examination of 12.5% of the medical records of patients who were examined in June 2010, and the survey on 19% 9% physicians and 9% nurses. The survey showed that about 40% of infectious diseases do are not reported by individual application forms. Most often not reported are fungal infections (99.7% unreported) and intestinal infectious diseases. From found diseases in a sample of medical records reviewed, only 1.4% of them were reported. Health professionals in 51% agree that reporting is not satisfactory, and in 49% of the cases agree that the great merit of this situation have the management of health institutions and local epidemiologists who do not organize professional meetings regarding the reporting on infectious diseases. A large number of health professionals (40%) do not fill properly report on the illness, so we have a 58% incorrectly filled forms that arrived in the Institute of Public Health. The health workers from Zenica-Doboj Canton did not sufficiently developed awareness about the need to report infectious diseases. In order to overcome this situation, management of health care institutions must have a responsible attitude towards the medical documentation and records, and binding continued medical education of health professionals to raise awareness about the importance of proper medical documentation management.