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Tekeli A.,University of YuzuncuYil | Rustu Kutlu H.,Cukurova University | Celik L.,Cukurova University
Bulgarian Journal of Agricultural Science | Year: 2014

The purpose of this study is to explore the effects of grape seed oil on growth performance, some blood parameters and fatty acid composition in broiler meat. In order to formulate isocaloric ratios, the corresponding amounts of soy oil were excluded from the rations accordingly with the addition of 0, 5, 10 and 15 g grape seed oil per kg. Four treatment groups were formed each consisting of 20 birds with similar initial body weights. Feed and water were given ad libitum. At the end of the experiment, no statistically significant difference was identified among the groups with respect to body weight gain, feed consumption and blood parameters (P>0.05). Feed conversion rate was improved in the group supplemented with 15g/kg grape seed oil (P<0.05). Grape seed oil inclusion was determined to be quadratically significant for carcass yield (P<0.05). The use of grape seed oil in the ration significantly increased the levels of C17:1 heptadecanoic acid, C18:3 linoleic acid and C20:1 eicosenoic acid in the meat which is known to have health-promoting effects for humans (P<0.05). The results have shown that nutritional composition of diets could affect the fatty acid composition of broiler meat. Hence, the findings of the study support the potential use of grape seed oil in functional broiler meat production for human nutrition, particularly for those with cardiovascular diseases. © 2014 National Centre for Agrarian Sciences. All rights reserved.

Dincel G.C.,Aksaray University | Yildirim S.,University of YuzuncuYil
International Journal of Clinical and Experimental Pathology | Year: 2016

Hyperglycemia plays a critical role in the development and progression of diabetic encephalopathy. A few studies have focused on a disintegrin and metalloprotease with thrombospondin type I repeats-13 (ADAMTS-13) expression in the central nervous system (CNS), and its function continues to remain unclear. The purpose of this study was to compare the expression of ADAMTS-13, neuron specific enolase (NSE), neurofilament (NF), neuronal nitric oxide synthase (nNOS) and glial fibrillary acidic protein (GFAP) in brain tissues of experimental streptozotocin (STZ)-induced diabetic rats. Expression of ADAMTS-13 (P < 0.001), nNOS (P < 0.001), NSE (P < 0.001) and NF (P < 0.001) expressions in the brain tissue markedly increased while GFAP decreased (P < 0.001) in diabetic animals versus controls. The most prominent finding of our study was that ADAMTS-13 expression increased significantly, suggesting that it may play an important function/s in the regulation and protection of the blood-brain barrier integrity and central nervous system microenvironment in diabetes. The results also suggested that nitric oxide production may increase due to increased nNOS expression and this also might contribute to neuropathology related with diabetes. Furthermore, increased expression of ADAMTS-13, NSE, NF and decreased expression of GFAP may give an idea of the disease progress and thus may have a critical diagnostic significance. To the best of the authors' knowledge, this is the first report on ADAMTS-13 expression in the CNS of STZ-induced diabetic animals.

Tabrizi R.,Shiraz University of Medical Sciences | Ozkan T.B.,University of YuzuncuYil | Mohammadinejad C.,Shiraz University of Medical Sciences
Journal of Craniofacial Surgery | Year: 2010

This is a retrospective study with the aim to evaluate orbital floor reconstruction with autogenous bone and alloplastic materials consisting of Medpor, Medpor Titan, Titanium, and resorbable plates. We evaluated 101 patients with pure blow-out fracture or concomitant with zygomatic maxillary fracture. We reviewed patients' documentation before and after surgery and 12 months after reconstruction. Thirteen patients with Medpor, 42 patients with Medpor Titan, 30 patients with Titanium, 5 patients with calvarial bone graft, 8 patients with iliac bone graft, and 3 patients with bioresorbable plates were treated. Medpore and Medpor-Titan-Medpor 1.5 to 2 mm in thickness were used. Autogenous bone graft 3 to 5 mm in thickness was used. Results showed that autogenous and alloplastic materials could be used in orbital floor reconstruction; autogenous bone graft had minimal postoperative infection, and it is a good choice in major orbital defects. Titanium mesh and MTM with excellent structural support are used in large orbital floor defects. Resorbable plates are good alternative materials in pediatric patients. © 2010 by Mutaz B. Habal, MD.

Tabrizi R.,Shiraz University of Medical Sciences | Ozkan B.T.,University of YuzuncuYil | Dehgani A.,Shiraz University of Medical Sciences | Langner N.J.,University of Innsbruck
Journal of Craniofacial Surgery | Year: 2012

Background and Purpose: The odontogenic keratocyst (OKC) is an unusual cyst with a high recurrence rate. The most common site for OKCs is by far the mandible. The best treatment of OKC remains controversial. Recurrence rates ranging anywhere from less than 10% to more than 60% have been reported. The aim of our study was to evaluate marsupialization as a treatment option for OKC. Methods: We managed 13 patients (8 male, 5 female) between the ages of 16 and 31 years (mean, 22.4 y) with biopsy-proven OKC. Radiographically, the patients' cyst sizes were between 25 and 90mm. Treatment consisted of marsupialization. We followed up with patients for a total duration of at least 60 months, and posttreatment visits were carried out at 6-month intervals. Results: We documented cured or reduced cyst size with radiography. The odontogenic keratocyst resolved completely in 10 patients, and the cyst walls shrank in 3 patients. The latter patients required a second operation to remove the associated impacted teeth. A histologic evaluation of 3 lesions showed metaplasia. Any case of recurring cysts was not seen during the entire follow-up period. Conclusions: Marsupialization is an effective and conservative treatment option for OKC. Nevertheless, future studies should conduct even longer follow-up periods to evaluate any recurrence of lesions. Copyright © 2012 by Mutaz B. Habal, MD.

Alimohammady M.,University of Mazandaran | Bagheri Z.,University of Mazandaran | Tunc C.,University of YuzuncuYil
International Journal of Control Theory and Applications | Year: 2015

In this article, we prove the generalized Hyers-Ulam-Rassias stability of the pexiderial functional equation f(ax + 2ay) + f(ax - 2ay) = 2ag(x) + 4ag(2y) - 8g(ay) in non-Archimedean normed spaces. © International Science Press.

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