Barrow N.J.,University of Western States
Plant and Soil | Year: 2015
Soil phosphate research has been hampered by the persistence of superseded ideas and language. Consequently few have recognised the two phosphate-sparing effects of previous phosphate fertilizer application: one caused by the decreased buffering capacity; the other caused by the eventual cessation of the diffusive movement of phosphate into the adsorbing particle. This is one cause of excessive phosphate applications and thence to contamination of water. © 2015 Springer International Publishing Switzerland
Jones-Schenk J.,University of Western States
Journal of Professional Nursing | Year: 2014
Over 1 million working registered nurses (RNs) currently do not have a bachelor's degree in nursing and comprise the critical group needing to return to school in order to achieve the Institute of Medicine's goal of 80% bachelors of science in nursing (BSNs) by 2020. Western Governors University (WGU) has developed a transformative educational model, incorporating 4 operational pillars (competency-based learning, technology, disaggregated faculty roles, and a student-centric management system), to revolutionize RN-BSN education. This article describes a successful contemporary model, disrupting most all of the traditional aspects of university education for professional nursing practice. The program design is of particular value to working adults and addresses the flexibility they need to accommodate academic advancement. The WGU nursing program currently serves over 5,000 students seeking BSN and Master of Science in Nursing degrees in all 50 states. © 2014 Elsevier Inc.
Meyer T.W.,Stanford University |
Hostetter T.H.,University of Western States
Kidney International | Year: 2012
There is renewed interest in identifying organic waste solutes that are normally excreted by the kidneys and must be removed by renal replacement therapy when the kidneys fail. A large number of these waste solutes are produced by colon microbes. Mass spectrometry is expanding our knowledge of their chemical identity, and DNA sequencing technologies are providing new knowledge of the microbes and metabolic pathways by which they are made. There is evidence that the most extensively studied of the colon-derived solutes, indoxyl sulfate and p-cresol sulfate, are toxic. Much more study is required to establish the toxicity of other solutes in this class. Because they are made in an isolated compartment by microbes, their production may prove simpler to suppress than the production of other waste solutes. To the extent that they are toxic, suppressing their production could improve the health of renal failure patients without the need for more intensive or prolonged dialysis. © 2012 International Society of Nephrology.
Wunderink R.G.,Northwestern University |
Waterer G.W.,Northwestern University |
Waterer G.W.,University of Western States
New England Journal of Medicine | Year: 2014
A 67-year-old woman with mild Alzheimer's disease who has a 2-day history of productive cough, fever, and increased confusion is transferred from a nursing home to the emergency department. According to the transfer records, she has had no recent hospitalizations or recent use of antibiotic agents. Her temperature is 38.4°C (101°F), the blood pressure is 145/85 mm Hg, the respiratory rate is 30 breaths per minute, the heart rate is 120 beats per minute, and the oxygen saturation is 91% while she is breathing ambient air. Crackles are heard in both lower lung fields. She is oriented to person only. The white-cell count is 4000 per cubic millimeter, the serum sodium level is 130 mmol per liter, and the blood urea nitrogen is 25 mg per deciliter (9.0 mmol per liter). A radiograph of the chest shows infiltrates in both lower lobes. How and where should this patient be treated? Copyright © 2014 Massachusetts Medical Society.
Ahluwalia M.S.,Cleveland Clinic |
Ahluwalia M.S.,University of Western States
Expert Review of Anticancer Therapy | Year: 2011
A number of important studies were presented at the Society for Neuro-Oncology annual meeting in Montréal, Canada, on 18-21 November 2010. Cediranib as monotherapy or in combination with lomustine did not show increased efficacy when compared with lomustine alone in patients with recurrent glioblastoma (GBM). Addition of temozolomide (TMZ) or irinotecan (CPT) to bevacizumab (BEV) in patients with recurrent GBM was well tolerated, with similar efficacy to BEV alone. The addition of BEV to radiation and TMZ in newly diagnosed GBM improved progression-free survival but did not improve overall survival. TMZ alone may be a reasonable approach in elderly GBM patients with poor performance status. Two Phase II trials with suntinib and vatalanib showed a hint of activity in patients with recurrent or progressive meningiomas. © 2011 Expert Reviews Ltd.