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Pensacola, FL, United States

The University of West Florida, also known as West Florida and UWF, is a mid-sized public university located in Pensacola, Florida, United States. UWF is a member institution of the State University System of Florida. The University of West Florida is a comprehensive research university without faculties of law or medicine. It is a space-grant institution that was established in 1963. The University of West Florida sits on the third largest campus in the State University System, 1,600 acres , and its campus is a natural preserve that is bordered by two rivers and Escambia Bay. The university's mascot is an Argonaut and its logo is the Chambered Nautilus. Wikipedia.

Goff R.D.,University of West Florida | Thorson J.S.,University of Kentucky
Organic Letters | Year: 2012

The Veratrum alkaloid cyclopamine, an inhibitor of cancer stem cell growth, was used as a representative scaffold to evaluate the inhibitory impact of glycosylation with a group of nonmetabolic saccharides, such as d-threose. In a five-step divergent process, a 32-member glycoside library was created and assayed to determine that glycosides of such sugars notably improved the GI 50 value of cyclopamine while metabolic sugars, such as d-glucose, did not. © 2012 American Chemical Society.

Martin G.D.A.,University of West Florida
Current Organic Chemistry | Year: 2010

The Rhizopus spp., in particular Rhizopus oryzae, are among the most frequently used whole cell biocatalysts. The fungus is known to catalyze the bioconversion of various reactive and non-reactive substrates with high regio-and stereoselectivities. The range of products obtained from these reactions has been attributed to the substrate binding modes within the enzyme's active site. More recently, an active site model has been developed to account for the reported bioconversions. The use of this model will prove useful in future syn-thetic and biotechnological applications. © 2010 Bentham Science Publishers Ltd.

Andrasik F.,University of West Florida
Cleveland Clinic Journal of Medicine | Year: 2010

Biofeedback-related approaches to headache therapy fall into two broad categories: general biofeedback techniques (often augmented by relaxation-based strategies) and methods linked more directly to the pathophysiology underlying headache. The use of general biofeedback-assisted relaxation techniques for headache has been evaluated extensively by expert panels and meta-analyses. Taken together, these reviews indicate that (1) various forms of biofeedback are effective for migraine and tension-type headache; (2) outcomes with biofeedback rival outcomes with medication therapy; (3) combining biofeedback with medication can enhance outcomes; and (4) despite efficacy in many patients, biofeedback fails to bring significant relief to a sizeable number of headache patients. Biofeedback methods that more directly target headache pathophysiology have focused chiefl y on migraine. These headache-specific approaches include blood volume pulse biofeedback, which has considerable supportive evidence, and electroencephalographic feedback.

Jonason P.K.,University of West Florida | Webster G.D.,University of Florida
Psychological Assessment | Year: 2010

There has been an exponential increase of interest in the dark side of human nature during the last decade. To better understand this dark side, the authors developed and validated a concise, 12-item measure of the Dark Triad: narcissism, psychopathy, Machiavellianism. In 4 studies involving 1,085 participants, they examined its structural reliability, convergent and discriminant validity (Studies 1, 2, and 4), and test-retest reliability (Study 3). Their measure retained the flexibility needed to measure these 3 independent-yet-related constructs while improving its efficiency by reducing its item count by 87% (from 91 to 12 items). The measure retained its core of disagreeableness, short-term mating, and aggressiveness. They call this measure the Dirty Dozen, but it cleanly measures the Dark Triad. © 2010 American Psychological Association.

Killgrove K.,University of West Florida | Tykot R.H.,University of South Florida
Journal of Anthropological Archaeology | Year: 2013

During the Empire, the population of Rome was composed mostly of lower-class free citizens and slaves. Viewed from historical records, the Roman diet included primarily olives, wine, and wheat, but poor and enslaved Romans may have eaten whatever they were able to find and afford, leading to significant heterogeneity in the Roman diet. Previous carbon and nitrogen isotope analyses of skeletons from Imperial Italy have begun to reveal variation in diet, but little is known about what people ate in the capital city. This study complements previous work by adding new isotope data from human skeletons found in two Imperial-period (1st-3rd centuries AD) cemeteries in Rome. These data suggest that urban and suburban diets differed, most notably in the consumption of the C4 grain millet. Comparing these new data with all published palaeodietary data from Imperial Italy demonstrates that significant variation existed in the diet of the common people. © 2012 Elsevier Inc.

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