The University of Valladolid is a public university in the city of Valladolid, province of Valladolid, in the autonomous region of Castile-Leon, Spain. Established in the 13th century, it is one of the oldest universities in the world. The university has 32,000 undergraduate students and more than 2,000 teachers. Wikipedia.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: COMPET-05-2015 | Award Amount: 1.50M | Year: 2016
A new and exciting era of planetary space exploration started in 2000 with a plethora of in-situ and orbital missions in operation at terrestrial planets and small Solar System bodies. The characterisation of the surface of these planetary objects is one of the major goals of space exploration. In order to support these operations, reduction and analyses of the space mission data, the PTAL (Planetary Terrestrial Analogues Library) project aims to build and exploit a multi-instrument spectral data base and joint spectral interpretation tools. We will determine mineral alteration pathways for natural and artificial terrestrial analogue materials under well-defined and controlled experimental conditions. The impact of varying environmental conditions (e.g., gas pressure, temperature, pH-value) will be tested to better constrain the geochemical aspect of habitable conditions on Mars, the prime target of this project. All natural and artificial rock samples and their alteration products will be characterised for the spectral library with commercial and dedicated spacecraft instrumentation (NIR, RAMAN, LIBS) under laboratory conditions, and where possible on in-situ field campaigns. Both the understanding of alteration pathways and coordinated analyses of the surface of Mars from orbital and landed platforms with new and well-characterised spectral data will allow unprecedented interpretations of the climatic and environmental evolution for materials detected at new landing sites using our well-defined experimental parameter space for deriving conditions and evolution of environment and climate at Mars. Defining and characterising the ingredients for habitability at yet another planet will broaden our conception on the origin and evolution of life on our own planet, and prepare future investigations of forthcoming space missions in which several project members are highly involved.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: LCE-21-2015 | Award Amount: 3.74M | Year: 2016
The transition to a low carbon economy needs to achieve multiple aims: competitiveness, protection of the environment, creation of quality jobs, and social welfare. Thus policy-makers and other key stakeholders require tools that need to focus beyond the energy sector by including these other domains of economy, society and the environment. Currently, most available tools lack integration of these important areas despite being tightly connected to the energy sector. Moreover, current energy modelling tools often lack documentation, transparency and have been developed for a specialized insider audience, which makes validation and comparison of results as well as independent review impossible. Our project aims to solve the current needs of integration and transparency by developing a leading-edge policy modelling tool based on WoLiM, TIMES and LEAP models and incorporating Input-Output Analysis, that allows for accounting of environmental, social and economic impacts. The modular design of the tool will take into account the necessary flexibility to deal with different levels and interests of stakeholders at great sectorial and spatial detail. Finally, transparency will be achieved through an open access freeware distribution of the model based on the open access programming language (Python), providing a detailed user manual, addressed to a wider non-specialist audience, and including free internet courses and learning materials.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: SPIRE-02-2016 | Award Amount: 6.54M | Year: 2016
The goal of CoPro is to develop and to demonstrate methods and tools for process monitoring and optimal dynamic planning, scheduling and control of plants, industrial sites and clusters under dynamic market conditions. CoPro will provide decision support to operators and managers and develop closed-loop solutions to achieve an optimally energy and resource efficient production. In most plants of the process industries, the energy and resource efficiency of the production depends critically on discrete decisions on the use of equipment, shutdowns, product changeovers and cleaning or regeneration of equipment. CoPro will consider these discrete decisions in plant-wide dynamic optimization and develop integrated scheduling and control solutions. Advanced online data analytics will be developed for plant health and product quality monitoring. The detection of anomalies will trigger fast re-scheduling and re-optimization. CoPro will demonstrate advanced plant-wide and site-wide coordination and control in five typical use cases that cover a wide range of sectors of the process industries, and the whole value chain: - Petrochemical production site - Base chemicals and polymer production site - Recycling system in cellulose production - Consumer product formulation and packaging plant - Food processing plant In addition,CoPro will develop methods for the coordination of plants in industrial parks that belong to different companies, thus providing a basis for future industrial symbiosis. CoPro pays special attention to the role of operators and managers in plant-wide control solutions and to the deployment of advanced solutions in industrial sites with a heterogeneous IT environment. As the effort required for the development and maintenance of accurate plant models is the bottleneck for the development and long-term operation of advanced control and scheduling solutions, CoPro will develop methods for efficient modelling and for model quality monitoring and model adaption
Agency: Cordis | Branch: H2020 | Program: CSA | Phase: EE-07-2015 | Award Amount: 1.71M | Year: 2016
INTENSSS-PA will support public authorities to integrate the energy theme into spatial planning and regional physical and socioeconomic landscapes. To achieve this objective INTENSS-PA will provide human and institutional capacity building to public authorities and to the wider network of private and public actors related to energy and regional planning by implementing the Living Lab concept, i.e. an innovative environment of co-creation. Specifically, a network of seven Regional Living Labs (RLL) within the seven different Countries/Regions that participate in the consortium (Thessaly-Greece, Calabria-Italy, Castilla y Leon- Spain, Association of Municipalities-Slovenia, Groningen-Netherlands, Triangle-Denmark and Zemgale-Latvia), will be created. Involving public authorities, private and civil society actors, the RLLs are focused on improving and designing a shared and integrated sustainable energy planning concept and on applying it in order to develop seven sustainable energy plans, i.e. one for each Region. The overall approach will involve learning sessions and experiential projects alongside intense networking. Communication and exploitation activities are envisaged including national Roadshows and a survey with policy makers. It is expected that over 200 people participate in the capacity-building activities performed within the RLLs network, while the stakeholders and policy makers informed on the project results and activities will exceed the 1000 individuals. The project objectives are completely inline with topic EE07s scope, since it considers innovative capacity building activities to public authorities for integrated energy planning through the establishment of a network of RLLs, i.e. of an ecosystem that stakeholders bring their own specific wealth of knowledge and expertise to the collective, helping to achieve boundary spanning knowledge transfer. Special consideration will be provided on planning requirements deriving from 27/2012/EU Directive.
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: INFRAIA-1-2014-2015 | Award Amount: 10.13M | Year: 2015
ACTRIS-2 addresses the scope of integrating state-of-the-art European ground-based stations for long term observations of aerosols, clouds and short lived gases capitalizing work of FP7-ACTRIS. ACTRIS-2 aims to achieve the construction of a user-oriented RI, unique in the EU-RI landscape. ACTRIS-2 provides 4-D integrated high-quality data from near-surface to high altitude (vertical profiles and total-column), relevant to climate and air-quality research. ACTRIS-2 develops and implements, in a large network of stations in Europe and beyond, observational protocols that permit harmonization of collected data and their dissemination. ACTRIS-2 offers networking expertise, upgraded calibration services, training of users, trans-national access to observatories and calibration facilities, virtual access to high-quality data products. Through joint research activities, ACTRIS-2 develops new integration tools that will produce scientific or technical progresses reusable in infrastructures, thus shaping future observation strategies. Innovation in instrumentation is one of the fundamental building blocks of ACTRIS-2. Associated partnership with SMEs stimulates development of joint-ventures addressing new technologies for use in atmospheric observations. Target user-groups in ACTRIS-2 comprise a wide range of communities worldwide. End-users are institutions involved in climate and air quality research, space agencies, industries, air quality agencies. ACTRIS-2 will improve systematic and timely collection, processing and distribution of data and results for use in modelling, in particular towards implementation of atmospheric and climate services. ACTRIS-2 invests substantial efforts to ensure long-term sustainability beyond the term of the project by positioning the project in both the GEO and the on-going ESFRI contexts, and by developing synergies with national initiatives.
Agency: Cordis | Branch: H2020 | Program: MSCA-ITN-EID | Phase: MSCA-ITN-2015-EID | Award Amount: 3.63M | Year: 2016
The typical lifetime of an industrial process plant is between 30 and 50 years. Technologies to enhance the operation and optimization of process plants can both guide the development of new state-of-the-art process plants and, perhaps more pertinently, can ensure that the large installed base of existing plants operates efficiently. The PRONTO Consortium partners are strongly convinced that for Europe to stay competitive, the overriding challenge is the efficient and sustainable operation of assets already installed and running at the present time. Production involves flows of material and energy over an extended area through the distributed and interconnected equipment of the process network. Process plants also generate complex information from disparate sources in the form of measurements from the process, mechanical and electrical sub-systems, and elsewhere. Efficient and sustainable operation of assets over a timescale of 30-50 years therefore requires sophisticated approaches for managing information and managing resources to ensure optimal operation. The research topics of PRONTO are (i) data analytics for assessment of the condition and performance of networks of equipment used for production in the process industries, (ii) optimization of use of resources in process networks taking account of real-time information about the condition and performance of the process equipment, and (iii) new concepts for process operation identified as having high potential for impact by industrial partners. The consortium partners include leading universities and well-known companies with high reputations for innovation. The consortium offers the early stage researchers training under the European Industrial Doctorate scheme by involving the non-academic sector extensively in joint supervision of the doctoral training with a strong emphasis on industrially-relevant PhD projects leading to practical demonstrations.
Agency: Cordis | Branch: H2020 | Program: MSCA-RISE | Phase: MSCA-RISE-2016 | Award Amount: 945.00K | Year: 2017
Severe ocular disorders are affecting the lives of more than 100Mill people world-wide and at least 25% of the population above 70 years of age, a growing demographic group in EU. More than 8 million people lose their lives to cancer every year, making cancer a leading cause of pre-mature mortality in the world. The main hallmarks of severe eye conditions (i.e angiogenesis, inflammation and vascular permeability) play also pivotal roles in cancer, being therapeutic targets to treat both kind of diseases. The overall goal of 3D-NEONET is the improvement of available treatments for cancer and ocular disease by enhancing drug discovery-development and delivery to targeted tissues, through advanced international co-operation between academic and non-academic partners. The interdisciplinary expertise provided by 18 partners in 7 countries encompasses among others: drug screens, ADME, toxicology, preclinical models, nanotechnology, biomaterials and clinical trials. After the success with ongoing FP7-IAPP project 3D-NET (Drug Discovery and Development of Novel Eye Therapeutics; (www.ucd.ie/3dnet), we are assembling 3D-NEONET, this enlarged European interdisciplinary consortium that will join forces and exchange skills to enhance current therapies in oncology and ophthalmology. The 3 global objectives of 3D-NEONET are: 1- Enhance the discovery and development of novel drugs, targets and biomarkers for ophthalmology and oncology. 2- Improve the Delivery of Therapeutics for Oncology and Ophthalmology 3- Enhancement of Research, Commercial and Clinical Trial Project Management Practices in these fields. Through participation in the program, 3D-NEONET is the vehicle for driving synergies between academic and non-academic partners leading to increased scientific and technological excellence as well as tangible innovative outputs that will strengthen the competitiveness of both the researchers and industries of the network even beyond the lifetime of the network.
Agency: Cordis | Branch: H2020 | Program: IA | Phase: WATER-1b-2015 | Award Amount: 8.43M | Year: 2016
Taking into account the current global water scarcity and the expensive operation and maintenance cost of wastewater treatment, INCOVER concept has been designed to move wastewater treatment from being primarily a sanitation technology towards a bio-product recovery industry and a recycled water supplier. A wastewater specific Decision Support System methodology will be tailored to the INCOVER technologies and provide data and selection criteria for a holistic wastewater management approach. Three added-value plants treating wastewater from three case-studies (municipalities, farms and food and beverage industries) will be implemented, assessed and optimised concurrently. INCOVER plants will be implemented at demonstration scale in order to achieve Technology Readiness Level(TRL) of 7-8 to ensure straightforward up scaling to 100,000 population equivalents (PE). INCOVER added-value plants will generate benefits from wastewater offering three recovery solutions: 1) Chemical recovery (bio-plastic and organic acids) via algae/bacteria and yeast biotechnology; 2) Near-zero-energy plant providing upgraded bio-methane via pre-treatment and anaerobic co-digestion systems; 3) Bio-production and reclaimed water via adsorption, biotechnology based on wetlands systems and hydrothermal carbonisation. To improve added-value production efficiency, INCOVER solutions will include monitoring and control via optical sensing and soft-sensors. INCOVER solutions will reduce at least a 50% overall operation and maintenance cost of wastewater treatment through the use of wastewater as a source for energy demand and added-value production to follow UE circular economy strategy. In addition, strategies to facilitate the market uptake of INCOVER innovations will be carried out in order to close the gap between demonstration and end-users. An estimated turnover of 188 million for INCOVER lead-users is expected after the initial exploitation strategy of 5 years implementing 27 INCOVER solutions.
RESPINE - REgenerative therapy of intervertebral disc: a double blind phase 2b trial of intradiscal injection of mesenchymal stromal cells in degenerative disc disease of the lomber SPINE unresponsive to conventional therapy
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: SC1-PM-11-2016-2017 | Award Amount: 5.56M | Year: 2017
The World Health Organisation (WHO) has included low back pain in its list of twelve priority diseases. Notably, Degenerative disc disease (DDD) presents a large, unmet medical need which results in a disabling loss of mechanical function. Today, no efficient therapy is available. Chronic cases often receive surgery, which may lead to biomechanical problems and accelerated degeneration of adjacent segments. Our consortium partners have developed and studied stem cell-based, regenerative therapies with encouraging results in phase 1 and 2a trials. Patients exhibited rapid and progressive improvement of functional and pain indexes by 50% within 6 months and by 65% to 78% after 1 year with no side effects. In addition, MRI T2 relaxation measurements demonstrated a significant improvement. To develop the worlds first rigorously proven, effective treatment of DDD, RESPINE aims to assess, via a multicentre, randomized, controlled, phase 2b clinical trial including 112 patients with DDD, the efficacy of an allogenic intervertebral mesenchymal stem cell (MSC)-based therapy. This innovative therapy aims to rapidly (within 3 months) and sustainably (at least 24 months) reduce pain and disability. In addition, the consortium aims to provide new knowledge on immune response & safety associated with allogeneic BM-MSC intradiscal injection. This simple procedure would be cost-effective, minimally invasive, and standardised. The transfer to the clinic will be prepared at a cost below 10k thanks to the strategy of production of allogenic cells, automation & EU standardisation. At the end of the RESPINE trial, we aim to propose a broadly available and clinically applicable treatment for DDD, marketed by European SMEs.
Agency: Cordis | Branch: H2020 | Program: MSCA-ITN-EJD | Phase: MSCA-ITN-2016 | Award Amount: 3.70M | Year: 2016
Throughout the 20th century, urban planning constituted itself as an important tool to spatially direct social developments. This applies to Europe more so than to any other continent. Urban planning contributed significantly to the emergence of the welfare state, strong economies and a relatively balanced settlement structure. However, urban planning also caused the suppression and destruction of some population groups, alongside natural and cultural resources. With the collapse of socialism in 1990, and the increasing importance of the EU, the 20th century ended with a multi-layered convergence in regard to the implementation of urban planning as a regulative and shaping instrument. Most studies on 20th century urban planning adopt a national perspective, while studies aiming to provide an overview focus on several core countries. Furthermore, methodological approaches are very heterogeneous. UrbanHists aim is to develop and sustainably promote a joint understanding of the history of urban planning in the 20th century from a European perspective. Complementing contributions of academic and non-academic partners will systematically increase the scientific level of the project. New knowledge, critical debates and dissemination will be strengthened. A reflective European identity will be promoted. UrbanHist intends to facilitate the breakthrough of the European planning history debate, which is currently in its initial phase of development. The four applying beneficiaries have different areas of expertise with regard to international planning history as well as international cooperation. They can look back on a long history of collaboration. The promotion of foreign doctoral students is part of daily university routine. In regard to the promotion and internationalisation of doctoral students, the four universities have already achieved a high standard.