University of Tuzla is a public university located in the city of Tuzla, Bosnia and Herzegovina. The university was founded in 1958. It became a proper university in 1976, and today is one of the major institutions of higher learning in Bosnia and Herzegovina. Wikipedia.
Delibegovic S.,University of Tuzla
Journal of Laparoendoscopic and Advanced Surgical Techniques | Year: 2012
Background: During laparoscopic appendectomy, the standard technique in securing the base of the appendix is by endoloop ligatures or a stapler. We earlier demonstrated the possibility of the application of a double Hem-o-lok® clip in securing of the base of the appendix. The application of only one plastic clip would, however, lower the cost of the laparoscopic procedure even further and shorten the surgery time. The objective of this prospective study was to evaluate the possible advantages of securing of the base of the appendix using only one Hem-o-lok clip. Patients and Methods: The 90 patients with acute appendicitis were randomly divided into three groups: In the first group, the base of the appendix was secured using one endoloop ligature, in the second group using a 45-mm stapler, and in the third group using only one nonabsorbable Hem-o-lok clip. The data collected included age, gender, surgery time, time of endoloop/stapler/clip application, hospital stay, costs associated with these, and intra-and postoperative complications. Results: There were no significant differences in hospital stay among the three groups of patients; but the average time of the operation was significantly longer in the endoloop group than in the stapler group (P=.002), whereas the endoloop and Hem-o-lok groups were not statistically different (P=.22). The time of application of the endoloop was significantly longer than for the stapler (P<.0001) and Hem-o-lok (P<.0001) groups. The time of application of the stapler was significantly shorter than that of the Hem-o-lok (P<.0001). However, the price of one endoloop is €28.85, for the stapler is €230.7, and for one Hem-o-lok clip is €2.35. Conclusion: The use of one Hem-o-lok clip is as safe as an endoloop and/or stapler; however, the time of the laparoscopic procedure using the Hem-o-lok was shorter in comparison with the use of an endoloop, with the cost of the procedure being the lowest. © 2012, Mary Ann Liebert, Inc.
Zerem E.,University of Tuzla |
Zerem E.,Academy of science and Arts of Bosnia and Herzegovina
World Journal of Gastroenterology | Year: 2014
Severe acute pancreatitis (SAP), which is the most serious type of this disorder, is associated with high morbidity and mortality. SAP runs a biphasic course. During the first 1-2 wk, a pro-inflammatory response results in systemic inflammatory response syndrome (SIRS). If the SIRS is severe, it can lead to early multisystem organ failure (MOF). After the first 1-2 wk, a transition from a pro-inflammatory response to an anti-inflammatory response occurs; during this transition, the patient is at risk for intestinal flora translocation and the development of secondary infection of the necrotic tissue, which can result in sepsis and late MOF. Many recommendations have been made regarding SAP management and its complications. However, despite the reduction in overall mortality in the last decade, SAP is still associated with high mortality. In the majority of cases, sterile necrosis should be managed conservatively, whereas in infected necrotizing pancreatitis, the infected non-vital solid tissue should be removed to control the sepsis. Intervention should be delayed for as long as possible to allow better demarcation and liquefaction of the necrosis. Currently, the step-up approach (delay, drain, and debride) may be considered as the reference standard intervention for this disorder. © 2014 Baishideng Publishing Group Inc. All rights reserved.
Ahmetovic E.,University of Tuzla |
Grossmann I.E.,Carnegie Mellon University
AIChE Journal | Year: 2011
We propose a general superstructure and a model for the global optimization for integrated process water networks. The superstructure consists of multiple sources of water, water-using processes, wastewater treatment, and pre-treatment operations. Unique features are that all feasible interconnections are considered between them and multiple sources of water can be used. The proposed model is formulated as a nonlinear programing (NLP) and as a mixed integer nonlinear programing (MINLP) problem for the case when 0-1 variables are included for the cost of piping and to establish optimal trade-offs between cost and network complexity. To effectively solve the NLP and MINLP models to global optimality we propose tight bounds on the variables, which are expressed as general equations. We also incorporate the cut proposed by Karuppiah and Grossmann to significantly improve the strength of the lower bound for the global optimum. The proposed model is tested on several examples. © 2010 American Institute of Chemical Engineers (AIChE).
Zvornicanin J.,University of Tuzla
Medicinski arhiv | Year: 2012
To assess the diagnostic value of ultrasonography in the detection of vitreo-retinal pathologies. This prospective study included all patients from retina department in Eye Clinic University Clinical Center Tuzla first time referred and examined by a single experienced vitreo-retinal surgeon in period from January 2011 to January 2012. Complete ophthalmic examination and ultrasonography-standardized echography were performed to all patients for detection and confirmation of vitreo-retinal pathology. Study included 146 eyes from 122 patients. 58 (39.7%) eyes had poor posterior segment visualization, 21 (14.4%) eyes due to dense cataracts and 37 (25.3%) eyes due to different vitreous opacities. 88 (60.3%) eyes had good or partial posterior eye segment visualization, where 67 (45.9%) eyes had proliferative vitreo-retinopathy and 55 (37.7%) eyes had tractional retinal detachment. Most common causes for referral to vitreo-retinal surgeon were ocular complications of diabetes mellitus 94 (64.4%), ocular trauma 18 (12.3%), rhegmatogenous retinal detachment 16 (10.9%) and intraocular inflammation 9 (6.2%). Ultrasonography confirmed suspected diagnosis and operative management plan in 120 (82.2%) eyes, sublassified previously established diagnosis in 19 (13%) eyes and helped further operative planning and established completely new diagnosis and changed initial management plan in 7 (4.8%) eyes. The final clinical diagnosis confirmed the ultrasonography findings in 142 from 146 (97.3%) eyes. Ultrasonography is useful part of ophthalmic examination for detection, evaluation and follow up of different vitreo-retinal pathologies.
Blbl K.,University of Tuzla
Computers and Operations Research | Year: 2011
In this paper, we study the job shop scheduling problem with the objective of minimizing the total weighted tardiness. We propose a hybrid shifting bottleneck-tabu search (SB-TS) algorithm by replacing the re-optimization step in the shifting bottleneck (SB) algorithm by a tabu search (TS). In terms of the shifting bottleneck heuristic, the proposed tabu search optimizes the total weighted tardiness for partial schedules in which some machines are currently assumed to have infinite capacity. In the context of tabu search, the shifting bottleneck heuristic features a long-term memory which helps to diversify the local search. We exploit this synergy to develop a state-of-the-art algorithm for the job shop total weighted tardiness problem (JS-TWT). The computational effectiveness of the algorithm is demonstrated on standard benchmark instances from the literature. © 2010 Elsevier Ltd. All rights reserved.
Pasic Z.,University of Tuzla
Medicinski arhiv | Year: 2011
Sleep disorders (SD) after stroke (stroke) are common occurrences, and most often in sleep apnea, insomnia and daytime sleepiness. GOALS. Research goals were to determine the types of SD and their frequency in patients with stroke in relation to the type of stroke and side of lesion. The study analyzed 200 patients with acute stroke hospitalized in the Clinic of Neurology, University Clinical Centre Tuzla in the period from 1st August 2007 to 1st June 2008. All patients have confirmed the existence of stroke by computerized tomography. SD was verified according to the General Curriculum of sleep, the Berlin questionnaire and Epvort scale. Stroke, by type, were divided into hemorrhagic and ischemic, and the localization of the stroke to right and left cerebral hemispheres. Of the total number of respondents, 78% had SD. Very serious level of SD had 42% of respondents, 20% moderate, and 16% of medium-severe degree. There was no statistically significant differences in the frequency of SD among patients with ischemic and hemorrhagic stroke (76.8%: 82.5%, p = 0.58). In relation to the side of lesion there was more patient with SD and stroke in the right cerebral hemisphere, but there were no statistically significant differences (39.5%: 33%, p = 0.1). According Epvort scale sleep apnea and snoring was present in 86%, daytime sleepiness in 49.5% and narcolepsy 0.5%. Sleep disturbance as a neuropsychological disorder has a significant incidence in the acute phase of stroke. SD is slightly more common in hemorrhagic stroke and stroke in the right hemisphere. Sleep Apnea and snoring are the most common types of SD in patients with stroke.
Smajlovic D.,University of Tuzla
Vascular Health and Risk Management | Year: 2015
Strokes in young adults are reported as being uncommon, comprising 10%–15% of all stroke patients. However, compared with stroke in older adults, stroke in the young has a disproportionately large economic impact by leaving victims disabled before their most productive years. Recent publications report an increased incidence of stroke in young adults. This is important given the fact that younger stroke patients have a clearly increased risk of death compared with the general population. The prevalence of standard modifable vascular risk factors in young stroke patients is different from that in older patients. Modifable risk factors for stroke, such as dyslipidemia, smoking, and hypertension, are highly prevalent in the young stroke population, with no signifcant difference in geographic, climatic, nutritional, lifestyle, or genetic diversity. The list of potential stroke etiologies among young adults is extensive. Strokes of undetermined and of other determined etiology are the most common types among young patients according to TOAST (Trial of Org 10172 in Acute Stroke Treatment) criteria. Prevention is the primary treatment strategy aimed at reducing morbidity and mortality related to stroke. Therefore, primary prevention is very important with regard to stroke in young adults, and aggressive treatment of risk factors for stroke, such as hypertension, smoking, and dyslipidemia, is essential. The best form of secondary stroke prevention is directed toward stroke etiology as well as treatment of additional risk factors. However, there is a lack of specifc recommendations and guidelines for stroke management in young adults. In conclusion, strokes in young adults are a major public health problem and further research, with standardized methodology, is needed in order to give us more precise epidemiologic data. Given the increasing incidence of stroke in the young, there is an objective need for more research in order to reduce this burden. © 2015 Smajlovic.
Sinanovic O.,University of Tuzla
Psychiatria Danubina | Year: 2010
Neuropsychology includes both the psychiatric manifestations of neurological illness (primary brain-based disorders) and neurobiology of «idiopathic» psychiatric disorders. Neurological primary brain disorders provoke broad spectrum of brain pathophysiology that cause deficit sin human behaviour, and the magnitude of neurobehavioral-related problems is a world wide health concern. Speech disorders of aphasic type, unilateral neglect, anosognosia (deficit disorders), delirium and mood disorders (productive disorders) in urgent neurology, first of all in acute phase of stroke are more frequent disorders then it verified in routine exam, not only in the developed and large neurological departments. Aphasia is common consequence of left hemispheric lesion and most common neuropsychological consequence of stroke, with prevalence of one third of all stroke patients in acute phase although exist reports on greater frequency. Unilateral neglect is a disorder that mostly effects the patient after the lesion of the right hemisphere, mostly caused by a cerebrovascular insult (infarct or haemorrhage affecting a large area - up to two thirds of the right hemisphere), and in general the left-side neglect is the most widespread neuropsychological deficit after the lesion of the right cerebral hemisphere. Reports on the incidence of visual neglect vary and they range from 13 to 85%. Anosognosia is on the second place as neuropsychological syndrome of stroke in right hemisphere, characterized by the denial of the motor, visual or cognitive deficit. This syndrome, defined as denial of hemiparesis or hemianopsia, is a common disorder verified in 17-28% of all patents with acute brain stoke. There are different reports on frequency of delirium in acute stroke, from 24 to 48%, and it is more frequent in hemorrhagic then ischemic stoke. Post stroke depression (PSD) is one of the more frequent consequences on the stroke, and the prevalence of PSD has ranged from 5 to 63% of patients in several cross-sectional studies, peaking three to six months after a stroke. © Medicinska naklada.
Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: HEALTH.2013.2.3.1-2 | Award Amount: 7.63M | Year: 2014
Invasive fungal disease (IFD) is a leading cause of morbidity and mortality in the growing number of immunocompromised individuals, including particularly cancer patients, and bone-marrow or organ transplant recipients. The majority of IFD events are still caused by Candida and Aspergillus species, but there is an increasing incidence of resistant or previously uncommon moulds, yeasts and Zygomycetes. Timely pathogen detection is a prerequisite for effective therapy in patients with IFD. FUNGITECT will focus on this medical priority and develop, validate and market a specific set of novel molecular diagnostic tests for IFD targeting fungal DNA-, RNA- and protein motifs, as well as the enzymatic activity of fungal pathogens. Additionally, FUNGITECT will provide a unique opportunity to establish and implement highly effective diagnostic assays supported by Next-Generation Sequencing and a bioinformatics service platform, facilitating optimized treatment strategies adapted to individual patient requirements with the following paramount aims: i) to provide the diagnostic basis for stratified and timely administration of the most appropriate antifungal therapy permitting improved management of patients with IFD, ii) to decrease the rate of overtreatment and the ensuing adverse side effects including fungal resistance, and iii) to help reduce the enormous healthcare costs for clinical antifungal therapy. The consortium includes leading academic research institutions, SMEs and Industry already successfully positioned in the market.
University of Tuzla | Date: 2012-10-23
The present invention relates to a dishwasher (1) comprising a washing tub (2) having a base (3), a rear wall (4) and two side walls (5) surrounding the base (3), a door (6) providing access to the washing tub (2), connected to the washing tub (2) from its lower side and opening by tilting forward, a rack (8) wherein objects to be washed are placed, having more than one roller (7) disposed at two opposite sides of its lower surface, providing it to move forwards/backwards, having a washing position whereat it is placed on the base (3) to entirely remain inside the washing tub (2), a loading position whereat it is positioned on the inner surface of the door (6) by being moved forwards when the door (6) is open and whereat loading-unloading can be performed and a spray arm (9) extending from the base (3) towards inside the washing tub (2), remaining under the rack (8) when the rack (8) is in the washing position, spraying water towards inside the rack (8) by rotating around itself.