Tunis, Tunisia
Tunis, Tunisia

The Tunis University is a university located in Tunis, Tunisia.It has been watchful, for sixteen years, for the best use of the human and material means granted to higher education and scientific research institutions it supervises to improve their opening on the social, cultural and economic environments.With the aim of a better rationalization of competence and insertion of the graduates into professional life, the University diversified the studies of master's degree and doctorate and multiplied the professional master’s degrees. That allowed it to respond to the needs of various sectors of the economy and to be in the avant-garde of scientific and technological evolution.The University of Tunis is a member of the Mediterranean University Union . Wikipedia.

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Agency: Cordis | Branch: FP7 | Program: CP-FP | Phase: ENV.2010.1.1.4-1 | Award Amount: 4.68M | Year: 2011

CLIM-RUN aims at developing a protocol for applying new methodologies and improved modeling and downscaling tools for the provision of adequate climate information at regional to local scale that is relevant to and usable by different sectors of society (policymakers, industry, cities, etc.). Differently from current approaches, CLIM-RUN will develop a bottom-up protocol directly involving stakeholders early in the process with the aim of identifying well defined needs at the regional to local scale. The improved modeling and downscaling tools will then be used to optimally respond to these specific needs. The protocol is assessed by application to relevant case studies involving interdependent sectors, primarily tourism and energy, and natural hazards (wild fires) for representative target areas (mountainous regions, coastal areas, islands). The region of interest for the project is the Greater Mediterranean area, which is particularly important for two reasons. First, the Mediterranean is a recognized climate change hot-spot, i.e. a region particularly sensitive and vulnerable to global warming. Second, while a number of countries in Central and Northern Europe have already in place well developed climate service networks (e.g. the United Kingdom and Germany), no such network is available in the Mediterranean. CLIM-RUN is thus also intended to provide the seed for the formation of a Mediterranean basin-side climate service network which would eventually converge into a pan-European network. The general time horizon of interest for the project is the future period 2010-2050, a time horizon that encompasses the contributions of both inter-decadal variability and greenhouse-forced climate change. In particular, this time horizon places CLIM-RUN within the context of a new emerging area of research, that of decadal prediction, which will provide a strong potential for novel research.

Soumaya K.,University of Tunis
Advances in Experimental Medicine and Biology | Year: 2013

Molecular components of impaired insulin signaling pathway have emerged with growing interest to under stand how the environment and genetic susceptibility combine to cause defects in this fundamental pathway that lead to insulin resistance. When insulin resistance is combined with β-cell defects in glucose-stimulated insulin secretion, impaired glucose tolerance, hyperglycemia, or Type 2 diabetes can result. The most common underlying cause is obesity, although primary insulin resistance in normal-weight individuals is also possible. The adipose tissue releases free fatty acids that contribute to insulin resistance and also acts as a relevant endocrine organ producing mediators (adipokines) that can modulate insulin signalling. This chapter deals with the core elements promoting insulin resistance, associated with impaired insulin signalling pathway and adipocyte dysfunction. A detailed understanding of these basic pathophysiological mechanisms is critical for the development of novel therapeutic strategies to treat diabetes. © 2012 Landes Bioscience and Springer Science+Business Media.

Grouzmann E.,University of Lausanne | Lamine F.,University of Tunis
Best Practice and Research: Clinical Endocrinology and Metabolism | Year: 2013

For more than 20 years, measurement of catecholamines in plasma and urine in clinical chemistry laboratories has been the cornerstone of the diagnosis of neuroendocrine tumors deriving from the neural crest such as pheochromocytoma (PHEO) and neuroblastoma (NB), and is still used to assess sympathetic stress function in man and animals. Although assay of catecholamines in urine are still considered the biochemical standard for the diagnosis of NB, they have been progressively abandoned for excluding/confirming PHEOs to the advantage of metanephrines (MNs). Nevertheless, catecholamine determinations are still of interest to improve the biochemical diagnosis of PHEO in difficult cases that usually require a clonidine-suppression test, or to establish whether a patient with PHEO secretes high concentrations of catecholamines in addition to metanephrines. The aim of this chapter is to provide an update about the catecholamine assays in plasma and urine and to show the most common pre-analytical and analytical pitfalls associated with their determination. © 2013 Elsevier Ltd. All rights reserved.

Petkova P.,University of Shumen | Boubaker K.,University of Tunis
Journal of Alloys and Compounds | Year: 2013

In this study, we try to give an explanation to the spectacular Urbach tailing associated to some nano-scale lattice disordering which has been recorded in (BSO) and germanates (BGO) compounds. Some experimental and theoretical items are presented in order to give a possible understanding to the controversial Urbach tailing: the Lattice Compatibility Theory (LCT). © 2012 Elsevier B.V. All rights reserved.

The manganese-doped crystals of bismuth titanates, germanates and sillenites are discussed in terms of the Urbach tailing and Faraday effect along with doping agent intrinsic lattice patterns. © 2013 Mendeleev Communications. All rights reserved.

Shatanawi W.,Hashemite University | Samet B.,University of Tunis
Computers and Mathematics with Applications | Year: 2011

Recently, Heman Kumar Nashine and Bessem Samet [H.K. Nashine, B. Samet, Fixed point results for mappings satisfying (ψ,φ)-weakly contractive condition in partially ordered metric spaces, Nonlinear Anal. 74 (2011) 22012209] studied some coincidence fixed point and common fixed point theorems for two mappings satisfying (ψ,φ)-weakly contractive condition in an ordered complete metric space. In the present paper, we study some coincidence fixed point and common fixed point theorems for three mappings S,T and R satisfying (ψ,φ)-weakly contractive condition in an ordered complete metric space, where the mappings S and T are assumed to be weakly increasing with respect to R. Our results generalize several well-known results in the literature. © 2011 Elsevier Ltd. All rights reserved.

Berzig M.,University of Tunis | Samet B.,University of Tunis
Computers and Mathematics with Applications | Year: 2012

We introduce the concept of fixed point of N-order for mappings F: XN→X, where N<2 and X is an ordered set endowed with a metric d. We establish fixed point results for such mappings satisfying a given contractive condition. Presented theorems extend and generalize the coupled fixed point results of Bhaskar and Lakshmikantham [T. Gnana Bhaskar, V. Lakshmikantham, Fixed point theorems in partially ordered metric spaces and applications, Nonlinear Anal. 65 (7) (2006) 1379-1393] and the tripled fixed point results of Berinde and Borcut [V. Berinde, M. Borcut, Tripled fixed point theorems for contractive type mappings in partially ordered metric spaces, Nonlinear Anal. 74 (2011) 4889-4897]. Some applications to integral equations and to matrix equations are also presented in this work. © 2012 Elsevier Ltd. All rights reserved.

Lefevre E.,University of Lille Nord de France | Elouedi Z.,University of Tunis
Decision Support Systems | Year: 2013

In the belief function framework, a unique function is induced from the use of a combination rule so allowing to synthesize all the knowledge of the initial belief functions. When information sources are reliable and independent, the conjunctive rule of combination, proposed by Smets, may be used. This rule is equivalent to the Dempster rule without the normalization process. The conjunctive combination provides interesting properties, as the commutativity and the associativity. However, it is characterized by having the empty set, called also the conflict, as an absorbing element. So, when we apply a significant number of conjunctive combinations, the mass assigned to the conflict tends to 1 which makes impossible returning the distinction between the problem arisen during the fusion and the effect due to the absorption power of the empty set. The objective of this paper is then to define a formalism preserving the initial role of the conflict as an alarm signal announcing that there is a kind of disagreement between sources. More exactly, that allows to preserve some conflict, after the fusion by keeping only the part of conflict reflecting the opposition between the belief functions. This approach is based on dissimilarity measures and on a normalization process between belief functions. Our proposed formalism is tested and compared with the conjunctive rule of combination on synthetic belief functions. © 2013 Elsevier B.V.

Agency: Cordis | Branch: FP7 | Program: CSA-SA | Phase: REGPOT-2009-2 | Award Amount: 1.07M | Year: 2010

The project BIODESERT aims to strengthen a molecular microbial ecology research platform already existing in Tunisia, which actively performs collaborative research for the development of straightforward strategies of Microbial Resource Management (MRM) for agriculture in arid environments. The final objective is to expand the existing platform and improving the related technical and research knowledge, for addressing agricultural problems and exploiting microbial biotechnology that can support the development of a bio-economy in Tunisia and North Africa. The idea behind BIODESERT is to create the conditions, in term of advanced research equipments and up-to-date know how, for developing research in the field of microbial applied biotechnology from the extremophiles living in the arid and desert environments characterizing Tunisia and North Africa. We believe that microorganisms living in these harsh environments hide important properties that could be exploited in agriculture for improving soil water retention, fertility and plant protection in arid ecosystems. For this purpose, BIODESERT intends to recruit three experienced researchers that will set up in the laboratory of the Tunisian partner a Microarray system, a Real Time-PCR and a confocal fluorescence microscope and will develop the most recent analytical techniques based on these advanced tools. The three researchers will benefit of training periods in two European laboratories (in Italy and Greece) that already use these technologies. These activities will result in the transfer of know how to the Tunisian partner that will be able to improve the research potential in the microbial biotechnology of arid ecosystem. By a careful dissemination strategy planned in the ambit of BIODESERT, the improved knowledge will be spread in the scientific environment and the society of Tunisia and other North African countries, promoting the application of MRM for improving agriculture sustainability in arid ecosystems.

Agency: Cordis | Branch: FP7 | Program: CP-FP | Phase: KBBE.2010.3.5-03 | Award Amount: 3.91M | Year: 2011

The project ULIXES aims to unravel, categorize, catalogue, exploit and manage the microbial diversity available in the Mediterranean Sea for addressing bioremediation of polluted marine sites. The idea behind ULIXES is that the multitude of diverse environmental niches of the Mediterranean Sea contains a huge range of microorganisms and their components (e.g. catabolic enzymes) or products (e.g. biosurfactant) that can be exploited in pollutant- and site-tailored bioremediation approaches. ULIXES intends to provide the proof of concept that it is possible to establish and exploit for bioremediation site-specific collections of microbial strains, mixed microbial cultures, enzymes, biosurfactants and other microbial products. These biotechnological resources will be mined by using approaches based on isolation of culturable microorganisms as well as by extensively applying advanced novel meta-omics technologies recently developed by the project partners and exclusively available for ULIXES. Three pollutant classes recognized worldwide as environmental priorities will be considered: petroleum hydrocarbons, chlorinated compounds and heavy metals. A large set of polluted environmental matrices from sites located all over the Mediterranean Sea will be explored, including seashore sands, lagoon sediments, deep sea sediments polluted by heavy oil hydrocarbons at oil tanker shipwreck sites, hypersaline waters and sediments from polluted salty coastal lakes and natural deep hypersaline anoxic submarine basins and mud volcanoes where hydrocarbon seepages occur. The mined collections of microbial biotechnological products will be exploited for development of novel improved bioremediation processes whose effectiveness will be proved by ex situ and in situ field bioremediation trials. A careful dissemination action will be pursued to assure capillary information of the ULIXES results and products to stakeholders and SMEs operating in the sector of marine bioremediation.

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