Ibaraki, Japan
Ibaraki, Japan

University of Tsukuba , one of the oldest national universities in Japan, is located in the city of Tsukuba, Ibaraki Prefecture in the Kantō region of Japan. The University has 28 college clusters and schools with a total of around 15,000 students . The main Tsukuba campus covers an area of 258 hectares , making it the largest single campus in Japan.It is famous for research in physics, economics, physical education and social science. Its Graduate School of Life and Environmental science is represented on the national Coordinating Committee for Earthquake Prediction. The university is one of the Japanese elite institutions of higher education as part of the Ministry of Education, Culture, Sports, Science and Technology's thirteen "Global 30" selected Project universities. Wikipedia.


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Patent
Kewpie Corporation and University of Tsukuba | Date: 2015-03-05

Hyaluronic acid modified with sphingosine-1-phosphate, and a medicine comprising the hyaluronic acid as an active ingredient, wherein the medicine can alleviate hepatic disorder caused by hypoxia/reoxygenation by protecting the liver sinusoidal endothelial cells, and the medicine can prevent and/or treat liver failure due to liver transplantation, hepatectomy, or other surgeries associated with liver ischemia/reperfusion.


Patent
Fujitsu Limited and University of Tsukuba | Date: 2016-08-04

A storage unit stores therein a collection of structures of biomolecules whose structure varies. A computing unit decreases a temperature set as a temperature parameter, which represents the temperature of the biomolecules, from a prescribed value in steps. When decreasing the temperature of the temperature parameter, the computing unit performs clustering on the structures included in the collection from before the decrease, detects detect outlier structures from the clustering result, and performs molecular dynamics simulations using the temperature parameter with the outlier structures as initial structures. Then, the computing unit stores structures generated by the molecular dynamics simulations in the storage unit.


Patent
Fujitsu Limited and University of Tsukuba | Date: 2016-08-04

An information processing apparatus includes: a memory configured to store a plurality of structures of a substance whose structure changes and a dimension group, which is a group of index dimensions that are indices for structural analysis of the substance, out of a plurality of dimensions that express the structure of the substance; and a processor configured to perform a procedure including: performing, for each of a plurality of candidate dimensions, which are not included in the dimension group, out of the plurality of dimensions, clustering of a plurality of structures in multidimensional space that has every index dimension included in the dimension group and a candidate dimension as coordinate axes; and adding a specified candidate dimension for which it is possible to generate a largest number of clusters to the dimension group as an index dimension.


Patent
Kewpie Corporation and University of Tsukuba | Date: 2017-01-11

Hyaluronic acid modified with sphingosine-1-phosphoate, and a medicine comprising the hyaluronic acid as an active ingredient, wherein the medicine can alleviate hepatic disorder caused by hypoxia/reoxygenation by protecting the liver sinusoidal endothelial cells, and the medicine can prevent and/or treat liver failure due to liver transplantation, hepatectomy, or other surgeries associated with liver ischemia/reperfusion.


Patent
University of Tsukuba and Nihon Kohden | Date: 2017-01-25

An electrocardiogram analyzer includes a first acquiring section that acquires a body surface electrocardiogram of a subject, a second acquiring section that acquires an intracardiac electrocardiogram of a ventricle of a heart of the subject, and an analyzing section that performs a frequency analysis on the intracardiac electrocardiogram and includes a range setting section that sets an analysis time range of the frequency analysis in the intracardiac electrocardiogram based on a unit waveform of the body surface electrocardiogram, and a calculating section that, in the analysis time range, performs the frequency analysis on the intracardiac electrocardiogram, and that calculates an index value indicating a ratio of local abnormal ventricular activities in the intracardiac electrocardiogram.


A biopotential can be measured with high accuracy without the electrodes coming into direct contact with the skin and without being affected by any motion artifact. The present invention comprises a first lead which detects a biopotential containing noise components, a second lead which is electrically isolated from the first lead and detects noise components, and a differential amplifier circuit which is input with a first signal output from the first lead and a second signal output from the second lead, and which amplifies and outputs a difference between the first signal and the second signal, wherein a value of an input impedance on the second signal side of the differential amplifier circuit is set so that the noise components detected from the second lead will have a frequency that is higher than a frequency spectrum of the biopotential.


Patent
Cyberdyne and University of Tsukuba | Date: 2017-04-19

There is provided a wearing-type movement assistance device capable of sufficiently ensuring a degree of freedom of the upper body and coping with a body type difference between wearers. The wearing-type movement assistance device includes a frame to be worn on an upper limb of a wearer, a drive unit provided in each of joints of the frame, a biomedical signal detection unit detecting a biological potential signal of the wearer, a joint angle detection unit detecting an angle of each joint, and a control unit controlling the drive unit based on the biological potential signal and the angle of each joint. The frame includes a vertical frame that extends in a vertical direction, a shoulder frame that is laterally provided in a shoulder width direction from an upper end of the vertical frame, a first arm frame having one end coupled to an end of the shoulder frame via a shoulder joint unit, and a second arm frame having one end coupled to the other end of the first arm frame via an intermediate joint unit and the other end connected to an elbow joint unit. The shoulder joint unit, the intermediate joint unit, and the elbow joint unit are provided with the drive unit.


Patent
Cyberdyne and University of Tsukuba | Date: 2017-04-19

Provided are a prosthesis-mounted action-assist device and a wearable action-assist device that enable step-over-step stair ascending and descending and achieve smooth switching between tasks in accordance with a motion of a wearer. The prosthesis-mounted action-assist device assists an action of a knee disposed between an upper leg frame and a lower leg frame of a prosthetic leg. The device includes an actuator applying power to the prosthetic leg, an absolute angle sensor detecting a hip angle relative to a vertical direction, an angle sensor detecting a knee angle, a floor reaction force sensor detecting a floor reaction force to a wearer, a data storage unit storing reference parameters of phases of tasks, and a control unit comparing the hip angle, the knee angle, and the floor reaction force with the reference parameters stored in the data storage unit to estimate a phase of a task of the wearer and generating an autonomous command signal for causing the actuator to produce power for the phase.


Polarization-sensitive optical image measurement is subject to a non-negligible bias, and consequent deviation in birefringence, in a surrounding range of low SN ratios (signal-to-noise ratios) and low signal strengths; however, this deviation in birefringence is removed to make accurate quantitative measurement possible. Noise-containing OCT signals obtained by polarization OCT are processed using a birefringence calculation algorithm, to obtain measured birefringence, after which noise is statistically adjusted to simulate a measured birefringence distribution and determine the noise characteristics of the measured birefringence values, and then Monte Carlo calculations are repeated by assuming different values for the noise level and the true birefringence value, respectively, to form three-dimensional histogram of combinations of true birefringence values, SN ratios, and measured birefringence values, after which specified measured birefringence values and SN ratios are assumed from the three-dimensional histogram information to obtain a true birefringence probability density distribution, and true birefringence values are estimated from the true birefringence probability density distribution.


Hatta Y.,University of Tsukuba
Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics | Year: 2012

We discuss the orbital angular momentum of partons inside a longitudinally polarized proton in the recently proposed framework of spin decomposition. The quark orbital angular momentum defined by Ji can be decomposed into the 'canonical' and the 'potential' angular momentum parts, both of which are represented as the matrix element of a manifestly gauge invariant operator. © 2012 Elsevier B.V.

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