Trieste, Italy

University of Trieste

www.units.it
Trieste, Italy

The University of Trieste is a medium-sized university in Trieste in the Friuli-Venezia Giulia region of Italy. The university consists of 12 faculties, boasts a wide and almost complete range of university courses and currently has about 23,000 students enrolled and 1,000 professors. It was founded in 1924.The historical international vocation of the University of Trieste is witnessed by its intense and high-level activity: Trieste is the centre of many research facilities, with which the University is connected.The number of international inter-university co-operation agreements rapidly increased these last years. These agreements involve staff and student mobility, both within EU Programmes like the Socrates programme and agreements exclusively concerned with research activities.In 2009, in the Il Sole 24 Ore National University Ranking, University of Trieste resulted the second best university in Italy. Moreover, in 2014, it was evaluated the second best Italian university by the Times Higher Education World University Rankings and the 201st worldwide. Wikipedia.


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Experimental method to detect the elastic modulus (E) of objects, samples, or semi-worked products, comprising the step of imparting a mechanical stress to the sample object (100) by means of an impact generated by a beating element (2) with respect to an inertial body (3); introducing an exciting body (5) of predetermined mass (m) between the beating element (2) and the sample object (100) so that the exciting body (5) is disposed in contact with the sample object (100) in correspondence with a contact surface (5a) having a predetermined extension value (S); imparting the mechanical stress on the sample object (100) by impacting the beating element (2) on the exciting body (5); acquiring a response signal corresponding to an elongation variation (X) of the sample object (100); processing a value of the elastic modulus (E) of the sample object (100) as a function at least of the extension value (S) of the contact surface (5a) and the value of an elongation variation (X) of the sample object (100).


Patent
University of Trieste | Date: 2017-01-04

A device (1) to detect the structural integrity of a sample object (100), comprising a beating element (2) configured to impart a mechanical stress of the impulsive type on the sample object (100), a rigid inertial body (3) configured to support the sample object (100) and to counteract rigidly the mechanical stress, acquisition means (4) to monitor a response signal from at least the stressed sample object (100) and operatively associated at least with the inertial body (3). The detecting device (1) comprises an exciting body (5) that can be activated on the sample object (100). The sample object (100) is in turn operatively associated with the acquisition means (4). The beating element (2) is such as to impart a mechanical stress to the sample object (100) impacting on the exciting body (5).


The present invention concerns the preparation of chemically modified derivatives of chitosan with acrylic groups and their use in the field of enamel-dentin adhesives. Chitosan derivatives have physical-chemical features (hydrophilicity, presence of electrical charges on the chain) which allow them to interact with the organic part of the demineralized tooth. At the same time, the acrylic groups incorporated in the polymer chain allow the formation of a covalent bond with the restorative material used in the dental field that is typically composed of acrylic resins. By combining the adhesion to the tooth surface and the bond with the restorative material, the chemically modified chitosan described herein is able to increase the lifespan of the dental restoration and can thus find use in the field of adhesives, in particular enamel-dentin adhesives.


Grant
Agency: European Commission | Branch: H2020 | Program: IA | Phase: MG-5.5a-2015 | Award Amount: 17.68M | Year: 2016

Port Cities can be seen as multidimensional laboratories where challenges connected with urban mobility are more complex due to the dual system of gravity centre: the city, the port, not to mention their shared hinterland.These peculiarities are at once a challenge and an opportunity, as they provide scope for planning, researching and implementing integrated mobility solutions in distinctively complex urban contexts. Civitas PORTIS designs, demonstrates and evaluates integrated sets of sustainable mobility measures in 5 major port cities located on the North Sea (Aberdeen and Antwerp), the Mediterranean Sea (Trieste), the Black Sea (Constanta), and Baltic Sea (Klaipeda). The project also involves a major international follower port city on the East China Sea (Ningbo). Thanks to the Civitas Initiative, the partner cities expect to prove that more efficient and sustainable mobility is conducive to the establishment of vital and multi-modal hubs for urban, regional, national and International movements of passengers and goods. To do this, they establish integrated living laboratories clustering local measures according to four major aspects of sustainable urban mobility: 1. Governance: to increase port-city collaborative planning and participation, leading to enhanced forms of SUMPs. 2. People: to foster less car-dependent mobility styles, leading to modal shift in favour of collective and more active transport. 3. Transport system: to strengthen the efficiency of road traffic management to/from the port and through the city, and foster the use of clean vehicles. 4. Goods: to enhance logistics and freight transport, improving the efficiency and coordination of city, port and regional freight movements. Working with port cities, Civitas PORTIS will generate a strong and twofold replication potential: 1) specifically to other port cities, and 2) more generally to cities presenting major transport nodes and attractors for the benefit of the whole CIVITAS Initiative.


Grant
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: SC1-HCO-02-2016 | Award Amount: 2.08M | Year: 2017

Molecular in vitro diagnostics and biomedical research have allowed great progress in personalised medicine but further progress is limited by insufficient guidelines for pre-analytical workflow steps (sample collection, preservation, storage, transport, processing etc.) as well as by insufficient quality assurance of diagnostic practice. This allows using compromised patients samples with post collection changes in cellular and extra-cellular biomolecules profiles thus often making diagnostic test results unreliable or even impossible. To tackle this, SPIDA4P aims to generate and implement a comprehensive portfolio of 22 pan-European pre-analytical CEN/Technical Specifications and ISO/International Standards, addressing the important pre-analytical workflows applied to personalized medicine. These will also applicable to biomarker discovery, development and validation as well as to biobanks. Corresponding External Quality Assurance (EQA) Schemes will be developed and implemented as well, aiming to survey the resulting quality of samples and diagnostic practice. SPIDIA4P will ensure stakeholder organisations involvements as well as training, education, and counselling as additional major foci of the project. The consortium will closely coordinate with large European public research consortia to obtain access to research and validation studies data serving as evidence for the new standards developments and achieved improvements of diagnosis, patient stratification and prognosis of disease outcome. At this crucial moment in the development of personalised medicine, SPIDIA4P proposes a coordination and support action that reunites 19 highly experienced partners in international standardisation for in vitro diagnostics, coming from private industry including SMEs, public institutions and from one official European Standards Organisation. This strong consortium is balanced and empowered to maximise the impacts of in vitro diagnostics on personalised medicine.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SFS-10b-2015 | Award Amount: 5.41M | Year: 2016

The overarching goal of VIVALDI is to increase the sustainability and competitiveness of the European shellfish industry by improving the understanding of bivalve diseases and by developing innovative solutions and tools for the prevention, control and mitigation of the major pathogens affecting the main European farmed shellfish species: Pacific oyster (Crassostrea gigas), mussels (Mytilus edulis and M. galloprovincialis), European flat oyster (Ostrea edulis), clams (Venerupis philipinarum) and scallops (Pecten maximus ). The project addresses the most harmful pathogens affecting either one or more of these shellfish species: the virus OsHV-1, Vibrio species including V. aestuarianus, V. splendidus, V. harveyi and V. tapetis, as well as the parasite Bonamia ostreae. The project is committed to provide practical solutions based on the most advanced knowledge. VIVALDI will dissect the disease mechanisms associated with pathogen virulence and pathogenesis and host immune responses, develop in vivo and in vitro models, and apply omic approaches that will help the development of diagnostic tools and drugs against pathogen targets, and breeding programmes in a collaborative effort with industrial partners. The proposal will include a global shellfish health approach, recognising that cultured bivalves are often exposed to several pathogens simultaneously, and that disease outbreaks can be due to the combined effect of two or more pathogens. The proposal will also investigate advantages and risks of the used of disease-resistant selected animals in order to improve consumer confidence and safety. VIVALDI will be both multi- and trans-disciplinary. In order to cover both basic and applied levels from molecules to farm, the proposal will integrate partners with a broad range of complementary expertises in pathology and animal health, epidemiology, immunology, molecular biology, genetics, genomics and food safety.


Grant
Agency: European Commission | Branch: H2020 | Program: SGA-RIA | Phase: FETFLAGSHIP | Award Amount: 89.00M | Year: 2016

This project is the second in the series of EC-financed parts of the Graphene Flagship. The Graphene Flagship is a 10 year research and innovation endeavour with a total project cost of 1,000,000,000 euros, funded jointly by the European Commission and member states and associated countries. The first part of the Flagship was a 30-month Collaborative Project, Coordination and Support Action (CP-CSA) under the 7th framework program (2013-2016), while this and the following parts are implemented as Core Projects under the Horizon 2020 framework. The mission of the Graphene Flagship is to take graphene and related layered materials from a state of raw potential to a point where they can revolutionise multiple industries. This will bring a new dimension to future technology a faster, thinner, stronger, flexible, and broadband revolution. Our program will put Europe firmly at the heart of the process, with a manifold return on the EU investment, both in terms of technological innovation and economic growth. To realise this vision, we have brought together a larger European consortium with about 150 partners in 23 countries. The partners represent academia, research institutes and industries, which work closely together in 15 technical work packages and five supporting work packages covering the entire value chain from materials to components and systems. As time progresses, the centre of gravity of the Flagship moves towards applications, which is reflected in the increasing importance of the higher - system - levels of the value chain. In this first core project the main focus is on components and initial system level tasks. The first core project is divided into 4 divisions, which in turn comprise 3 to 5 work packages on related topics. A fifth, external division acts as a link to the parts of the Flagship that are funded by the member states and associated countries, or by other funding sources. This creates a collaborative framework for the entire Flagship.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: PHC-02-2015 | Award Amount: 5.99M | Year: 2016

The goal of this multidisciplinary project is to comprehensively characterise high-grade serous ovarian cancer (HGS-OvCa) at single-cell level, identify the best combination of drug combination to kill HGS-OvCa populations and commercialise a predictive biomarker kit for finding the right therapeutic regimen to the right patient. This project takes an advantage on prospectively and longitudinally collected fresh sample specimens from multiple anatomic sites of HGS-OvCa patients with metastatic disease. Fluorescence activated cell sorting and recently developed mass cytometry are used to identify subpopulations in HGS-OvCa tumors. This is followed by single-cell analysis at genetic and transcriptomics levels, and ex vivo drug screening experiments. These data will be used to establish network models to predict the most effective combinatorial treatments. The key results will be validated with existing HGS-OvCa data together with prospective and retrospective cohorts and in vivo models. The clinically most actionable treatment suggestions from our modelling efforts will be translated to HGS-OvCa patient care. Ovarian cancer kills more than 40,000 women in Europe every year due to lack of effective and long-lasting therapeutic regimens. HERCULES presents an innovative strategy to suggest effective treatments that lead to a marked decrease in ovarian cancer deaths and reduce the number of expensive but inefficient treatments. Our approach paves the way to move beyond the current trial-and-error clinical assessment of drug combinations toward more systematic prediction of the most effective drug combinations for each patient. The proposed approach will be a major breakthrough in systems medicine and will benefit individual ovarian cancer patients and the health-care system through more effective treatments, and the diagnostic and pharmaceutical industry through tools for better stratified clinical trials, and novel treatment and diagnostic modalities.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: NMBP-23-2016 | Award Amount: 3.90M | Year: 2017

The mission of COMPOSELECTOR is to develop a Business Decision Support System (BDSS), which integrates materials modelling, business tools and databases into a single workflow to support the complex decision process involved in the selection and design of polymer-matrix composites (PMCs). This will be achieved by means of an open integration platform which enables interoperability and information management of materials models and data and connects a rich materials modelling layer with industry standard business process models. In order to satisfy the need for effectively designing and producing increasingly sophisticated materials, components and systems with advanced performance on a competitive time scale there is a particular need in industry for chemistry/physics-based materials models and modelling workflows which capture the performance of materials, accounting for material internal microstructure and effects of processing, provide accuracy/validation of predicted data, and relevant management of uncertainty and assemble knowledge ready for decision makers to act upon. COMPOSELECTOR will address these needs by integration of (discrete and continuum) materials models and process models as well as structured and unstructured data into a standards-based, open integration framework, implementing uncertainty management and multi-criteria optimisation in order to provide actionable choices, and building tailored knowledge apps to support decision makers. The human interface of COMPOSELECTOR will be supported by Visual Analytics capable of integrating qualitative, quantitative and cognitive aspects for a user-friendly management of the vast quantity of available data. The COMPOSELECTOR BDSS will be applied to and validated by end users targeting accurate, reliable, efficient and cost effective decision-making and management of polymer matrix composite (PMC) materials in the transport and aerospace value chains.


Grant
Agency: European Commission | Branch: H2020 | Program: MSCA-RISE | Phase: MSCA-RISE-2016 | Award Amount: 1.24M | Year: 2017

Investing in energy efficiency and saving is crucial to support energy accessibility and environmental protection, and it is the worlds best interest to share and implement forms of energy efficiency. This implies a stronger and effective transnational policy to promote and disseminate know-how about new technologies both at the market and R&D level. In this respect, development of projects centered on energy efficient technologies based on nanostructured organic materials certainly is a strategic field. The progresses in mastering organic matter by self-assembly and self-organization to form ordered soft-materials revolutionized the field opening new frontiers for both fundamental and applied research. However the route towards organic materials for application at the industrial scale is restricted by difficulties in the control and manipulation of the structural organization at the molecular level and its manifestation at higher scales. Motivated by the potential for significant energy savings, the INFUSION project aims to create a strongly interdisciplinary and inter-sectorial environment in which the principles of self-organization are poured from the Academia into the private sector and vice-versa to create new paradigms to engineer electrochromic devices. Through a detailed plan of 83 secondments, the project aims at cross-fertilize the electrochromic technology joining specific expertise to realize a bottom-up approach toward the design, preparation and characterization of self-organized organic materials (chromophores, CNSs, polymers...) at different interfaces (ITO, graphene) and exhibiting superior performances (optical, durability). For the transfer of knowledge, the project combines the multidisciplinary expertise of 6 universities, 1 research institute, and 3 companies representing 4 EU and 2 TC countries (Pakistan and Argentina) in the field of organic chemistry, photochemistry, surface science, polymer and materials science, and device engineering.

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