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Chatzigeorgiou K.-S.,National and Kapodistrian University of Athens | Ikonomopoulou C.,National and Kapodistrian University of Athens | Kalogeropoulou S.,National and Kapodistrian University of Athens | Siafakas N.,National and Kapodistrian University of Athens | And 9 more authors.
Diagnostic Microbiology and Infectious Disease

Prosthetic valve and pacemaker lead endocarditis by Staphylococcus lugdunensis remain very rare, while the former is associated with an ominous prognosis. Two cases involving a prosthetic aortic valve and a pacemaker lead, respectively, are reported. Despite disease severity and delayed diagnosis, patients recovered fully with combined antimicrobial and surgical treatment. © 2010 Elsevier Inc. Source

Giannoukas A.D.,University of Thessalia Medical School

Superficial thrombophlebitis is a manifestation of thrombosis that involves the superficial venous system of the lower limb. It is frequently underreported and is considered an insignificant entity. In some cases it may coexist with deep vein thrombosis, or may extend from the superficial system to the deep veins, increasing the risk of complications such as pulmonary embolism. Diagnosis by ultrasound scanning is essential to exclude deep venous thrombosis and confirm the extent of the superficial thrombophlebitis. When superficial thrombophlebitis coexists with deep vein thrombosis, or when the main trunk of the saphenous veins in the vicinity of the junctions is affected, treatment with low molecular weight heparins should be initiated. © 2013 Les Laboratoires Servier-All rights reserved throughout the world and in all languages. Source

Papagiannis D.,University of Thessaly | Rachiotis G.,University of Thessaly | Symvoulakis E.K.,Private Practice | Daponte A.,University of Thessalia Medical School | And 3 more authors.
Journal of Multidisciplinary Healthcare

Background: There are still sparse data on vaccination coverage against human papillomavirus (HPV) among students in the health professions. The aim of this study was to investigate HPV vaccination coverage in female students from the health professions in Greece. Methods: A self-administered, anonymous questionnaire was distributed to second-year and third-year female students pursuing degrees in medicine, nursing, and paramedical health disciplines in central Greece. Results: Overall vaccination coverage was 44.3%. The major reason for lack of vaccination was fear about safety of the vaccine. Participants who had received information about safety of the vaccine from the mass media and paramedical students had lower vaccination coverage in comparison with students who had received information about vaccine safety from alternative sources. Conclusion: Further quantitative and qualitative research is needed to design educational activities targeting female students in the health professions in order to create a positive domino effect and improve HPV vaccination coverage levels in Greece. © 2013 Papagiannis et al. Source

Klontzas M.E.,University of Crete | Zibis A.H.,University of Thessalia Medical School | Karantanas A.H.,University of Crete
American Journal of Roentgenology

OBJECTIVE. Osteoid osteoma is a benign bone tumor that is commonly located in the proximal femur. Although CT is helpful in the diagnosis of osteoid osteoma, patients in whom the clinical presentation of the tumor is atypical are first referred to undergo MRI, which yields a high percentage of false-negative or inconclusive results. We sought to explore the association between a half-moon sign of bone marrow edema and the presence of osteoid osteoma of the femoral neck. SUBJECTS AND METHODS. The MRI examinations of 11 consecutive patients with osteoid osteoma (group 1) were prospectively included in the study. In addition, 950 consecutive hip MRI examinations of 485 patients were retrospectively analyzed for the presence of bone marrow edema of the femoral neck, with 19 patients identified as having bone marrow edema resulting from causes other than osteoid osteoma (group 2). Patients in both study groups were evaluated for the presence of the half-moon sign. RESULTS. The half-moon sign of bone marrow edema was significantly associated with the presence of osteoid osteoma (p < 0.0001), having been seen on the MR images of all 11 patients in group 1 and only one of 19 patients in group 2. MRI examination was therefore 94.7% specific and 100% sensitive for the detection of osteoid osteoma, with positive and negative predictive values of 91.7% and 100%, respectively. CONCLUSION. The half-moon sign is an MRI finding that is highly specific and sensitive for an accurate diagnosis of osteoid osteoma of the femoral neck. © American Roentgen Ray Society. Source

Stergioti E.,National and Kapodistrian University of Athens | Deligeoroglou E.,National and Kapodistrian University of Athens | Economou E.,National and Kapodistrian University of Athens | Tsitsika A.,National and Kapodistrian University of Athens | And 4 more authors.
Gynecological Endocrinology

Anorexia nervosa is a serious eating disorder that is associated with decreased bone mineral density and greater lifetime risk for fractures. This case-controlled study, analyzed single nucleotide polymorphisms of genes encoding vitamin D receptor, estrogen receptor alpha (ESR1), collagen type I and calcitonin receptor (CTR). Relationships between genotype and body mass index, cycling status and lumbar spine bone mineral density (LBMD) were determined in 40 adolescent girls with anorexia nervosa and 10 age-matched controls. The distribution of CTR-AluI genotypes differed between groups, but this polymorphism was not associated with LBMD Z-score. Distribution of ESR1-XbaI genotypes did not differ between groups, but the AA genotype was associated with decreased LBMD Z-score (≤-1) (OR = 24.79, 95% CI, 1.01-606.08). Carriers of the A allele were more likely to have decreased LBMD Z-scores compared with carriers of the G allele (OR = 4.12, 95% CI, 1.23-13.85, p = 0.022). In conclusion, our study shows that anorexic patients with wild-type genotype ESR-XbaI receptor are in greater risk for decreased BMD in relation to those with the mutated gene. Prompt recognition of these patients is crucial because early administration of the proper therapeutic treatment may contribute to the prevention of adverse sequelae on bone metabolism. © 2013 Informa UK Ltd. Source

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