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Objective: To describe the demographic and clinical characteristics of patients undergoing coronary artery bypass graft surgery (CABG) and to test their relation to mortality. Methods: This study was a retrospective medical record review of 655 consecutive patients undergoing CABG from May 2002 to April 2010. Results: Of the 655 patients, 12.1% died during the hospital stay. Mortality was significantly (p<0.05) higher in females (17.3%), aged < 70 years (22.8%), in emergency surgery (36.4%), in cases of readmission to the intensive care unit (ICU) (33.3%), when the stay in the ICU was < three days (16.3%), undergoing longer cardiopulmonary bypass (CPB), and with more comorbidities (15.4%). Predictor variables of death identified with logistical regression analysis were: female (OR=2.04), age > 70 years (OR=2.69), emergency surgery (OR=15.43) and urgency (OR=3.81), performance of CPB (OR=2.19) and readmission to the ICU (OR=4.33). Conclusion: Variables such as female sex, increased age, type of surgery, readmission to the ICU, ICU stay, comorbidities, and duration of CPB influence the outcome death in patients undergoing CABG. Thus, such aspects should be considered to reduce hospital mortality in patients undergoing such surgery. Source

Franco S.C.,University of the Region of Joinville | Hernaez A.M.,Rovira i Virgili University
Ciencia e Saude Coletiva

Distinct models of health management reflect the core principles upon which they were founded and their institutional arrangement can lead to the improvement of health policy. This paper seeks to reflect on the potential benefits and limitations of the organizational structure and the social capital to lead to changes in the performance of public health organizations in the quest for enhanced quality of care. The description and analysis of two experiences of universal public health systems, in Catalonia and in Brazil, reveal similarities in the legal basis of both health systems. However, the mode of deployment differed greatly, which gave rise to divergent management experiences. One prioritized managerial organization, while the other concentrated on the importance of the social actors promoting the institutionalization of social capital. It is suggested that models of management with dialogue between an efficient organizational design and citizen participation capable of constructing social capital may lead to change in the organizational culture and enhance the quality of care. Source

Scolaro B.,Regional University of Blumenau | Delwing-De Lima D.,University of the Region of Joinville | Da Cruz J.G.P.,Regional University of Blumenau | Delwing-Dal Magro D.,Regional University of Blumenau
Oxidative Medicine and Cellular Longevity

Objective. The aim of this study was to evaluate the influence of acute and chronic intake of mate tea on the effects elicited by acute and chronic administration of ethanol. Methods. Oxidative stress was evaluated by measuring thiobarbituric acid-reactive substances (TBARS), as well as the activities of the antioxidant enzymes, catalase (CAT), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) in the hippocampus and blood of rats. Male Wistar rats were randomly assigned to four groups, for both acute and chronic treatment: (1) control group, (2) treated group, (3) intoxicated group, (4) and intoxicated group treated with mate tea. Results. Both ethanol administrations significantly increased TBARS in plasma and hippocampus of rats and altered antioxidant enzyme activities, changes which were reverted by mate tea administration. Conclusions. Data indicate that acute and chronic ethanol administration induced oxidative stress in hippocampus and blood and that mate tea treatment was able to prevent this situation. Copyright 2012 Bianca Scolaro et al. Source

The association between attention deficit and hyperactivity disorder (ADHD) and epilepsy can cause significant impact on the social life of affected individuals and their families. Clinical studies suggest that 30-40% of people with epilepsy also have ADHD. There are no studies which demonstrate that short or long-term treatment with methylphenidate increases the risk of seizures. Some studies attempt to relate drug interactions between methylphenidate and antiepileptic drugs, but adverse effects of methylphenidate have not been shown clearly. This review presents some neurobiological and physiopathogenic aspects, common to ADHD and epilepsy, from recent research studies, related to pharmacology, neuroimaging and electroencephalography. Possible risk of occurrence of seizures associated with the use of methylphenidate are also discussed. Source

Calopadia saxicola is described as new to science. The species grows on rocky shores in southern Brazil and is characterized by the corticate thallus, pruinose apothecia with brownish to reddish brown disc, mainly 2-3-spored asci with muriform ascospores, and the absence of secondary metabolites. A description with ecological data, figures, comments and a key to all species in the genus known from Brazil are given. © 2015 British Lichen Society. Source

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