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Apiquian R.,University of the Americas in Mexico | Cordoba R.,Nervous system research center cisne | Louza M.,University of Sao Paulo
Neuropsychiatric Disease and Treatment | Year: 2011

Background: Risperidone long-acting injection (RLAI) has been shown to be efficacious, improve compliance, and increase long-term retention rate on therapy. The aim of this work was to determine the effect of RLAI on clinical outcome and hospitalization rate in patients with schizophrenia or schizoaffective disorder enrolled in the electronic Schizophrenia Treatment Adherence Registry in Latin America. Methods: Data were collected at baseline, retrospectively for the 12 months prior to baseline, and prospectively every three months for 24 months. Hospitalization prior to therapy was assessed by a retrospective chart review. Efficacy and functioning were evaluated using Clinical Global Impression of Illness Severity (CGI-S), Personal and Social Performance (PSP), and Global Assessment of Functioning (GAF) scores. Relapse and treatment were also registered. Results: Patients were recruited in Mexico (n = 53), Brazil (n = 11), and Colombia (n = 15). Sixty-five percent (n = 52) were male, and mean age was 32.9 years. Patients were classified as having schizophrenia (n = 73) or schizoaffective disorder (n = 6). The mean dose of RLAI at six months was 34.1 mg (standard deviation = 10.2 mg). The percentage of hospitalized patients before treatment was 28.2% and 5.1% at six months after initiating RLAI (P, 0.001). Significant changes were registered on CGI-S, GAF, and PSP scores. Conclusions: RLAI was associated with an improvement in clinical symptoms and functioning, and a greater reduction in hospitalization. © 2011 Fornaro et al, publisher and licensee Dove Medical Press Ltd.


PubMed | Dana-Farber Cancer Institute, Stanford University, University of Western Australia, The Surgical Center and 18 more.
Type: | Journal: JAMA oncology | Year: 2016

A major challenge in value-based health care is the lack of standardized health outcomes measurements, hindering optimal monitoring and comparison of the quality of health care across different settings globally. The International Consortium for Health Outcomes Measurement (ICHOM) assembled a multidisciplinary international working group, comprised of 26 health care providers and patient advocates, to develop a standard set of value-based patient-centered outcomes for breast cancer (BC). The working group convened via 8 teleconferences and completed a follow-up survey after each meeting. A modified 2-round Delphi method was used to achieve consensus on the outcomes and case-mix variables to be included. Patient focus group meetings (8 early or metastatic BC patients) and online anonymized surveys of 1225 multinational BC patients and survivors were also conducted to obtain patients input. The standard set encompasses survival and cancer control, and disutility of care (eg, acute treatment complications) outcomes, to be collected through administrative data and/or clinical records. A combination of multiple patient-reported outcomes measurement (PROM) tools is recommended to capture long-term degree of health outcomes. Selected case-mix factors were recommended to be collected at baseline. The ICHOM will endeavor to achieve wide buy-in of this set and facilitate its implementation in routine clinical practice in various settings and institutions worldwide.


Huertas Talon J.L.,University of Zaragoza | Cisneros Ortega J.C.,University of the Americas in Mexico | Lopez Gomez C.,University of Zaragoza | Ros Sancho E.,University of Zaragoza | Faci Olmos E.,University of Zaragoza
CAD Computer Aided Design | Year: 2010

This paper proposes a method of manufacturing a spur tooth gear in Ti-6Al-4V alloy (grade 5) using a wire electrical discharge machine (Wire EDM). A geometrical model for the gear is drawn up and implemented using the program MATLAB. The electro-erosion parameters tested for this alloy are applied to an ONA PRIMA S-250. The parameters used (power, pause, voltage, ...) are based on the ONA EDM charts. The Taguchi orthogonal array method was chosen to obtain the optimum values for cutting Titanium. The work presented follows established lines for manufacturing mechanical parts using general purpose machines and tools. In this case, the WEDM process was used. The MATLAB program was employed to obtain the interpolation points. This program simplifies the task of solving the equations originated by the mathematical model which allows the wire path to be calculated. The WEDM method used here is a commendable alternative for machining electrically conductible materials which are difficult to work with using conventional machine tools (milling, turning or boring). Furthermore, the WEDM process reduces or even eliminates the need for subsequent polishing processes due to the high-quality finish achieved. © 2009 Elsevier Ltd. All rights reserved.


Cisneros-Limon R.,Japan National Institute of Advanced Industrial Science and Technology | Vazquez-Gonzalez J.L.,University of the Americas in Mexico | Mendoza-Vazquez J.R.,Technological Institute of Puebla ITP
IEEE International Conference on Intelligent Robots and Systems | Year: 2015

This paper gives an analytical description for the ideal and the real workspace of a 6-RSS parallel robot; that is, by considering its geometrical and its mechanical constraints. The ideal workspace is described as a set of inequalities representing a 3D volume that encloses valid attitudes, whose frontier can be plotted as a 3D surface by using Constructive Solid Geometry and an adaptive polygonization method. The real workspace represents a subset of the ideal one, determined by the presence of joint limits at the spherical joints. These ones arise from the fact that these spherical joints are not ideal, but implemented as spherical plain bearings. However, although it is not straight forward to express these joint limits in an analytical way, it was possible to find an analytical expression to describe the real workspace, represented by additional inequalities that must be met by a desired attitude of the platform. © 2015 IEEE.


Rosas-Cholula G.,National Institute of Astrophysics, Optics and Electronics | Ramirez-Cortes J.M.,National Institute of Astrophysics, Optics and Electronics | Alarcon-Aquino V.,University of the Americas in Mexico | Martinez-Carballido J.,National Institute of Astrophysics, Optics and Electronics | Gomez-Gil P.,National Institute of Astrophysics, Optics and Electronics
Proceedings - 2010 IEEE Electronics, Robotics and Automotive Mechanics Conference, CERMA 2010 | Year: 2010

This paper describes an experiment on the detection of a P-300 rhythm from electroencephalographic signals for brain computer interfaces applications. The P300 evoked potential is obtained from visual stimuli followed by a motor response from the subject. The EEG signals are obtained with a 14 electrodes Emotiv EPOC headset. Preprocessing of the signals includes denoising and blind source separation using an Independent Component Analysis algorithm. The P300 rhythm is detected through a time-scale analysis based on the discrete wavelet transform (DWT). Comparison using the Short Time Fourier Transform (STFT), and Wigner-Ville Distribution (WVD) indicates that the DWT outperforms the others as an analyzing tool for P300 rhythm detection. © 2010 IEEE.


After the earthquake and tsunami that struck the south-central Chile on February 27, 2010, it is necessary to anticipate the psychological consequences of disasters such causes in the population. This paper reviews the results of various studies worldwide in order to understand these consequences, focusing mainly on posttraumatic stress disorder [PTSD], their characteristics, prevalence, risk factors and interventions used for prevention and treatment. Then, we propose a model of narrative intervention, enriched by the contributions of studies on emotional expression and social support in the prevention of this disorder. This proposal has been tried before successfully for the prevention of PTSD and associated symptoms in women with breast cancer. Copyright 2010 by Sociedad Chilena de Psicología Clínica.


Kozanoglu B.,University of the Americas in Mexico | Rubio F.,University of the Americas in Mexico
Thermal Science | Year: 2014

Natural convection from a downward facing horizontal heated plate was analyzed. An expression for the thickness of the thermal boundary layer was obtained in terms of Rayleigh number. Assuming this thickness as the characteristic length of the problem, the data published by other authors were modified and an equation for Nusselt number is presented. It was observed that this equation correlates the data more precisely than the commonly known equations in the literature that employ the ratio of the area to the perimeter or the shorter side of the plate as the characteristic length. It is concluded that taking the thermal boundary layer as the characteristic length of phenomenon is a proper approach and correlates all the data closely.


Osorio M.,University of the Americas in Mexico | Santoyo A.,University of the Americas in Mexico
CEUR Workshop Proceedings | Year: 2012

Logical and mathematical programming arc closely related, however, for some reasons, this has not generated widespread interest in the scicntific community to study more deeply this connection, and perhaps one reason is that the scicntific community has focused only on the direct benefits of each paradigm. At the same time, logic programming has been used for addressing typical decision analysis's conccrns, such as solving decision problems under uncertainty (which arc addressed by decision theory), and ccrtain optimization problems (which arc addressed by mathematical programming methods). Therefore, this paper proposes to make research on structural similarities between logical and mathematical programming, as well as algorithms, and technological and theoretical foundation that help us to crcatc synergy between them lead us to have a new approach, for solving decision analysis problems.


Torres-Mancera M.T.,Metropolitan Autonomous University | Baqueiro-Pena I.,University of the Americas in Mexico | Figueroa-Montero A.,Metropolitan Autonomous University | Rodriguez-Serrano G.,Metropolitan Autonomous University | And 3 more authors.
Biotechnology Progress | Year: 2013

The highest enzymatic extraction of covalent linked chlorogenic (36.1%) and caffeic (CA) (33%) acids from coffee pulp (CP) was achieved by solid-state fermentation with a mixture of three enzymatic extracts produced by Aspergillus tamarii, Rhizomucor pusillus, and Trametes sp. Enzyme extracts were produced in a practical inexpensive way. Synergistic effects on the extraction yield were observed when more than one enzyme extract was used. In addition, biotransformation of chlorogenic acid (ChA) by Aspergillus niger C23308 was studied. Equimolar transformation of ChA into CA and quinic acids (QA) was observed during the first 36 h in submerged culture. Subsequently, after 36 h, equimolar transformation of CA into protocatechuic acid was observed; this pathway is being reported for the first time for A. niger. QA was used as a carbon source by A. niger C23308. This study presents the potential of using CP to produce enzymes and compounds such as ChA with biological activities. © 2013 American Institute of Chemical Engineers.


Majewski T.,University of the Americas in Mexico | Alejos R.,University of the Americas in Mexico
CONIELECOMP 2011 - 21st International Conference on Electronics Communications and Computers, Proceedings | Year: 2011

The paper presents the dynamic system that moves in continuous way thanks to its vibration. The principle of the method, the mathematical model, and some results are presented. Two or more segments models were taken for the analysis. It is shown that at presence of internal excitation and non-symmetrical Coulomb dry friction a motion with a constant average velocity is possible and this motion is stable. The average velocity is defined as a function of the frequency and amplitude of the excitation. © 2011 IEEE.

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