Southampton, United Kingdom
Southampton, United Kingdom

The University of Southampton is a public university located in Southampton, England. Southampton is a research intensive university and a founding member of the Russell Group of elite British universities.The origins of the university date back to the founding of the Hartley Institution in 1862 following a legacy to the Corporation of Southampton by Henry Robertson Hartley. In 1902, the Institution developed into the Hartley University College, with degrees awarded by the University of London. On 29 April 1952, the institution was granted a Royal Charter to give the University of Southampton full university status. It is a member of the European University Association, the Association of Commonwealth Universities and is an accredited institution of the Worldwide Universities Network.Besides being recognised as one of the leading research universities in the UK, Southampton has also achieved consistently high scores for its teaching and learning activities. It additionally has one of the highest proportions of income derived from research activities in Britain, and is regularly ranked in the top 100 universities in the world. As of 2014 Southampton is one of the few universities to achieve a top 20 UK position in the most established national and international rankings .The University of Southampton currently has over 16,000 undergraduate and 7,000 postgraduate students, making it the largest university by higher education students in the South East region. The university has seven teaching campuses. The main campus is located in the Highfield area of Southampton and is supplemented by four other campuses within the city: Avenue Campus housing the Faculty of Humanities, the National Oceanography Centre housing courses in Ocean and Earth science, Southampton General Hospital offering courses in Medicine and Health science, and Boldrewood Campus an engineering and maritime technology campus housing also the university's strategic ally Lloyd's Register. In addition, the university operates a School of Art based in nearby Winchester and an international branch in Malaysia offering courses in Engineering. Each campus is equipped with its own library facilities.The university has over 5000 places at university-owned halls of residence, spread over two main complexes and several other smaller halls located within a couple of miles from the university. The University of Southampton Students' Union, provides support, representation and social activities for the students ranging from involvement in the Union's four media outlets to any of the 200 affiliated societies and 80 sports. The university owns and operates a sports ground at nearby Wide Lane for use by students and also operates a sports centre on the main campus. Highfield Campus also houses three main art venues supported by the university and Arts Council England. Wikipedia.


Time filter

Source Type

Patent
University of Southampton | Date: 2016-10-07

Disclosed herein include compositions and methods of modulating protein expression that utilizes an activator or a repressor of a non-sense mediated RNA decay switch exon (NSE). In some embodiments, also included herein are compositions and methods of modulating protein expression that uses an agent that targets a transposed element.


Patent
University of Southampton | Date: 2016-09-29

Methods for converting an alcohol, such as cyclohexanol to a ketone, such as cyclohexanone, include reacting the alcohol in the presence of a catalyst and oxygen to produce the ketone. In one exemplary embodiment, the catalyst comprises a microporous copper chloropyrophosphate framework including a plurality of noble metal nanoparticles. In one exemplary embodiment, the noble metal nanoparticles include at least one metal selected from the group consisting of platinum, palladium, and gold.


Patent
University of Southampton | Date: 2017-04-12

An anti-resonant hollow-core fiber comprising a first tubular, cladding element which defines an internal cladding surface, a plurality of second tubular elements which are attached to the cladding surface and together define a core with an effective radius, the second tubular elements being arranged in spaced relation and adjacent ones of the second tubular elements having a spacing therebetween, and a plurality of third tubular elements, each nested within a respective one of the second tubular elements.


A method of fabricating at least one single-crystal alloy semiconductor structure, comprising : forming at least one seed on a substrate for growth of at least one single-crystal alloy semiconductor structure, the at least one seed containing an alloying material; providing at least one structural form on the substrate which is crystallized to form the at least one single-crystal alloy semiconductor structure, the at least one structural form being formed of a host material and comprising a main body which extends from the at least one seed and a plurality of elements which are connected in spaced relation to the main body; heating the at least one structural form such that the material of the at least one structural form has a liquid state; and cooling the at least one structural form, such that the material of the at least one structural form nucleates at the least one seed and crystallizes as a single crystal to provide at least one single-crystal alloy semiconductor structure, with a growth front of the single crystal propagating in the main body of the respective structural form away from the respective seed; wherein the plurality of elements of each structural form provide reservoirs of the alloying material in liquid state, such that successive ones of the plurality of elements act to maintain, in liquid state, an available supply of the alloying material to the growth front of the single crystal in the main body of the respective structural form.


Patent
University of Southampton | Date: 2015-06-08

An anti-resonant hollow-core fiber comprising a first tubular, cladding element which defines an internal cladding surface, a plurality of second tubular elements which are attached to the cladding surface and together define a core with an effective radius, the second tubular elements being arranged in spaced relation and adjacent ones of the second tubular elements having a spacing therebetween, and a plurality of third tubular elements, each nested within a respective one of the second tubular elements.


Through a combination of in vitro and in vivo approaches, the inventors show that human IgG2 (h2) delivers unique FcR-independent agonistic activity to anti-CD40 antibodies and to antibodies specific to other immunostimulatory receptors, including 4-1BB and CD28. Investigation of an anti-human CD40 mAb, LOB7.4, revealed that the unique activity of h2 was dependent upon the precise arrangement of hinge and CH1 disulfide bonds. Chemical shuffling or mutagenesis to lock LOB7.4 into either a more flexible h2A or more compact h2B conformation endowed antagonistic and agonistic properties, respectively. Engineering of h2 in this way allows development of reagents with either immunostimulatory or immunosuppressive characteristics, with direct implication for the design of therapeutic mAb agents and fusion proteins.


A method of fabricating at least one single-crystal alloy semiconductor structure, comprising: forming at least one seed on a substrate for growth of at least one single-crystal alloy semiconductor structure, the at least one seed containing an alloying material; providing at least one structural form on the substrate which is crystallized to form the at least one single-crystal alloy semiconductor structure, the at least one structural form being formed of a host material and comprising a main body which extends from the at least one seed and a plurality of elements which are connected in spaced relation to the main body; heating the at least one structural form such that the material of the at least one structural form has a liquid state; and cooling the at least one structural form, such that the material of the at least one structural form nucleates at the least one seed and crystallizes as a single crystal to provide at least one single-crystal alloy semiconductor structure, with a growth front of the single crystal propagating in the main body of the respective structural form away from the respective seed; wherein the plurality of elements of each structural form provide reservoirs of the alloying material in liquid state, such that successive ones of the plurality of elements act to maintain, in liquid state, an available supply of the alloying material to the growth front of the single crystal in the main body of the respective structural form.


Patent
University of Southampton | Date: 2017-03-15

This invention relates to NK cell activation and NK cell mediated immunity, immunogenic peptides, compositions and complexes; and associated methods of treatment or prophylaxis. In particular, a peptide capable of activating NK cell- mediated immunity, the peptide comprising or consisting of the amino acid sequence XnAX2X1 wherein Xn is an amino acid sequence of between 5 and 12 residues, and X1 is any amino acid; or leucine or isoleucine; and X2 is alanine, threonine, tryptophan, or serine.


Patent
University of Southampton | Date: 2017-04-26

A method of forming an optical fibre assembly, comprises providing a planar substrate made of a first material; positioning an optical fibre with an outer layer of a first glass material on a surface of the substrate to form a pre-assembly; depositing a further glass material such as silica soot onto the pre-assembly, over at least a part of the optical fibre and adjacent parts of the substrate surface; and heating the pre-assembly to consolidate the further glass material into an amorphous volume in contact with at least parts of the surface of the substrate and the outer layer of the optical fibre, thereby bonding the optical fibre to the substrate to create the optical fibre assembly.


Patent
University of Southampton | Date: 2017-03-08

Methods and apparatus for generating droplets are disclosed. In one arrangement a peristaltic screw pump is configured to drive pulsatile flows of fluids in different conduits which are phased relative to each other such that a sequence of droplets are formed at a junction downstream from the pump.

Loading University of Southampton collaborators
Loading University of Southampton collaborators