University of South Asia of Pakistan

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Lahore, Pakistan
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Mushtaq S.,The University of Lahore | Chaudhry M.A.,The University of Lahore | Rahman H.M.A.,University of South Asia of Pakistan
Bangladesh Journal of Pharmacology | Year: 2015

Abies pindrow is widely used in traditional practice for the treatment of diarrhea and bronchitis and the present study was designed to validate its folkloric uses. The crude extract of A. pindrow inhibit spontaneously contracting (1-10 mg/mL) and high K+ (80 mM)-induced pre-contracted rabbit jejunum (3 mg/mL) in concentration dependent manner. A rightward shift in Ca+2 concentration response curves was seen in the presence of crude extract (0.1-0.3), similar to verapamil. In isolated tracheal tissue, A. pindrow inhibited, high K+ and carbachol (1 μM)-induced contractions, at 3 mg/mL and 10 mg/mL respectively, similar to that caused by verapamil. These results indicate the presence of calcium channels blocked activity in crude extract of A. pindrow, which provide sound basis for medicinal uses of A. pindrow in diarrhea and bronchitis. © 2015, Bangladesh Pharmacological Society. All right resreved.


Ikhlaq S.,Government of Punjab | Javid M.A.,The University of Nizwa | Qayyum T.I.,University of South Asia of Pakistan
Transport Problems | Year: 2017

This study aims to evaluate the intercity bus terminals in metropolitan Lahore, Pakistan. In this regard eleven intercity bus terminals of Lahore (three government-owned & eight privately owned) were selected. Evaluation of performance indicators (PIs) for a sustainable design of intercity bus terminals was conducted with the help of different surveys. Six PIs on user perception were evaluated, i.e., safety and security, access, information, connection and reliability, environment and allied facilities. The bus terminals and PIs were also ranked according to user satisfaction. The results showed that the privately owned intercity bus terminals perform better and are more likely to be sustainable as compared with government-owned terminals. Likewise, the users indicated more satisfaction with the privately owned terminals. In addition, the users rated 'safety and security' as the most important among the six PIs. It is recommended to establish standards for sustainable design of intercity bus terminals using the six PIs as measures of performance.


Shahab M.B.,The University of Lahore | Wahla M.A.,University of South Asia of Pakistan | Mushtaq M.T.,The University of Lahore
2015 38th International Conference on Telecommunications and Signal Processing, TSP 2015 | Year: 2015

This paper proposes a downlink resource scheduling technique for maximized throughput with reduced Block Error Ratio and improved fairness among different users across the cellular region. Resources are allocated to users on the basis of Channel Quality Indicator feedback values in a way that the data rates are increased without compromising on Block Error Ratio and fairness. Channel Quality Indicator feedback values provide critical information about the channel, which enables the scheduler to perform radio resource management functions in the downlink. Simulations are performed on a link level simulator for different scenarios. Results of simulations have been demonstrated, thoroughly explained and compared with the existing scheduling techniques designed for high data rates with and without fairness. © 2015 IEEE.


Waqas M.K.,Islamia University of Bahawalpur | Akhtar N.,Islamia University of Bahawalpur | Shah P.A.,University of Punjab | Danish M.Z.,University of Punjab | And 3 more authors.
Pakistan Journal of Pharmaceutical Sciences | Year: 2016

The aim of current research was to develop a water-in-oil emulsion containing grape seed extract for application in cosmeceuticals. Finally grinded dried grape seeds powder was extracted with hydro alcoholic mixture. Emulsions consisting of different concentrations of cetyl dimethicone (Abile EM90), the nonionic emulsifier, liquid paraffin as oily phase and water as aqueous phase were developed. Color, odor, pH, viscosity, liquefaction, phase separation, centrifugation and thermal stability of the formulated emulsions were observed at various storage temperatures i.e. 8±0.5°C, 25±0.5°C, 40±0.5°C and 40°C±0.5°C with 70% RH. The stable formulation consist of 16% mineral oil, 4% of ABIL EM 90®, 4% grape seeds extract, 1% rose oil and 75% distilled water. All the results derived from this study showed good stability over the three months study period which indicates w/o emulsion can be used as carrier of 4% grape seeds extract to enhance desired effects when applied topically.


Saeed A.,University of South Asia of Pakistan | Raana T.,Government of Pakistan | Saeed A.M.,Kinnaird College for Women | Humayun A.,SheikhKhalifa Bin Zayed Al Nahyan Medical College
Nutrition Journal | Year: 2016

Background: In Pakistan, incidence of antenatal depression ranges from 18 to 80 %, which goes undiagnosed, resulting in maternal and neonatal implications. The current study aimed to examine the association of antenatal depression with maternal dietary intake and neonatal outcome. Methods: A hospital-based, prospective cohort study was conducted on 94 middle class antenatal attendees coming to a tertiary care hospital in Lahore, Pakistan at the beginning of second trimester. Participants fulfilling eligibility were enrolled consecutively after taking written informed consent. Exposure group was identified by Edinburgh Postnatal Depression Scale (EPDS) and cohort members were followed till after delivery. Maternal dietary intake was assessed by 24-h Recall and Food Frequency Checklist, while neonatal outcome was identified through patient files before discharge. Data on potential confounders was collected. Loss to follow up was 13 % (82/94). Data was collected from April-September 2013. Results for 82 participants were analyzed using SPSS version 21. Results: EPDS screened 35/82 (43 %) eligible antenatal attendees as depressed, out of which 16/35 (20 %) were severely depressed and 19/35 (23 %) were moderately depressed. Incidence of poor maternal dietary intake was more in females with antenatal depression. Antenatal depression increased the risk of poor Healthy Eating Index (RR = 2.58, C.I 1.60-5.23, AR = 62 %), carbohydrate <175 gm (RR = 1.188, CI 0.836-1.688, AR = 15 %), protein <71 gm (RR = 1.343, CI 1.059-1.703, AR = 26 %) and fat <55 gm (RR = 2.954, CI 1.612-5.416, AR = 67 %) Incidence of neonatal outcomes included, Fetal Growth Retardation (RR = 2.70, C.I 0.69-3.70, AR = 60 %), preterm birth (RR = 1.60, C.I 0.72-2.45, AR = 54 %), low Apgar score (RR = 2.70, C.I 0.69-3.70, AR = 60 %) and Low Birth Weight (RR = 0.56, C.I 0.93-1.39, AR = -44 %). Conclusion: Antenatal women with depression developed poor dietary intake and had increased incidence of Fetal Growth Retardation, preterm birth and low Apgar score, but not of Low Birth Weight. © 2016 The Author(s).


Masood K.,Institute of Nuclear Medicine and Oncology | Zafar J.,COMSATS Institute of Information Technology | Zafar J.,University of South Asia of Pakistan | Zafar H.,National University of Ireland
IEEE Transactions on Plasma Science | Year: 2012

A directly heated line source emitter with beam power (>50 KW/cm 2) is developed. The emitter assembly design parameters and beam characteristics are analyzed using a highly uniform magnetically confined region. Circular cross-sectional tungsten cathodes of diameters 0.9 mm and 1.5 mm were used, and their results are compared. The developed emitter configuration ensures low angular divergence, millisecond evaporation time for large samples, operational reproducibility, and beam stability. The emitter source has been tested by experimentally developing extremely homogeneous magnetic field in large cylindrical region of more than one-half of the coil's diameter. © 2012 IEEE.


Nassar R.-U.-D.,University of South Asia of Pakistan | Soroushian P.,Michigan State University | Ghebrab T.,Texas Tech University
Resources, Conservation and Recycling | Year: 2013

Field investigation of high-volume fly ash (HVFA) concrete in pavement construction was carried out. Test results performed on cores drilled from pavement after 270 days of concrete age showed that use of HVFA results in production of pavement concrete with improvements in: strength; moisture barrier qualities; and abrasive resistance characteristics. These improvements are brought about by the pozzolanic reaction of fly ash with the hydrates of cement that favorably changes the microstructure and interfacial transition zone in the resulting concrete. Use of high volume of fly ash in pavement concrete as partial replacement for cement is estimated to produce major energy and environmental gains and is a practice that is aimed at producing durable and sustainable concrete-based infrastructure. The use of HVFA concrete can significantly economize the construction of concrete pavements and improve the service life of transportation infrastructure. © 2013 Elsevier B.V.


Nesbitt R.C.,London School of Hygiene and Tropical Medicine | MacKey S.,London School of Hygiene and Tropical Medicine | Kuper H.,London School of Hygiene and Tropical Medicine | Muhit M.,In.Sight | And 2 more authors.
Disability and Rehabilitation | Year: 2012

Purpose: Making services available to children with disabilities in low- and middle-income countries does not guarantee their use. This study aims to identify factors associated with the uptake of referrals in order to investigate barriers to service use. Methods: Children with impairments identified in two districts of Bangladesh were invited to attend screening camps where their condition was confirmed; they were provided with referrals for rehabilitation and treatment services. Predictors of referral uptake were identified using logistic regression. Results: Overall referral uptake was 47%, 32% in Sirajganj and 61% in Natore. There was no association between age or gender and referral uptake. Factors predictive of referral uptake were higher income in Sirajganj (OR=2.6 95%CI 1.4-5.0), and the districts combined (OR=1.6 95%CI 1.1-2.1); maternal literacy in Natore (OR=1.6 95%CI 1.0-2.5); and epilepsy in all three models (Sirajganj: OR=2.6 95%CI 1.7-4.0; Natore: OR=13.5 95%CI 6.52-8.3; Combined: OR=4.6 95%CI 3.36.5). Physical impairment was associated with increased odds of uptake in Sirajganj and in the combined model (OR=2.7 95%CI 1.84.1; OR=3.34 95%CI 2.2-5.2). Conclusions: Even when some logistical and financial assistance is available, children with impairment from low-income families may require additional support to take up referrals. There may be greater willingness to accept treatment that is locally provided, such as medication for epilepsy or therapy at village level. Implications for Rehabilitation Providing a referral for treatment or rehabilitation is often not enough to ensure access to service for children with disabilities in low and middle income countries. Uptake of referral can be influenced by many factors, and individuals face different types of barriers. Financial and logistical support can help increase referral uptake. Low monthly income and maternal illiteracy is associated with lower uptake even when assistance is provided. © 2012 Informa UK, Ltd.


Saleem U.,University of Punjab | Saleem U.,Government College University at Faisalabad | Ahmad B.,University of South Asia of Pakistan | Hussain K.,University of Punjab | And 2 more authors.
Asian Journal of Chemistry | Year: 2014

Herbal products are consistently inconsistent due to a number of factors and their standardization is tedious task, and considering its importance, the present study aims to develop and validate an easy method for the standardization of extracts/products prepared from Euphorbia helioscopia (Family: Euphobiaceae) which is a traditional medicinal plant. Three pharmacologically active compounds such as quercetin, myricetin and kaempferol were used as analytical markers to develop and validate a reversed-phase HPLC method. The standards were eluted through column (Eclipse XDB-C18, 5 μm, 4.6 x 150 mm) using isocratic mobile phase comprising methanol and 0.2 % phosphoric acid (65: 35, v/v). The flow rate was kept at 1 mL/min, temperature of the column was maintained at 30°C and detection was carried out at 360 nm. The method was found to be linear for all the three standards in the whole range investigated (R2 = 0.982 to 0.998). The limit of detection (LOD) and limit of quantification (LOQ) for quercetin and myricetin were 0.04 and 0.15 μg/mL, respectively, and kaempferol 0.54 and 1.81 μg/mL. The method showed repeatability and reproducibility with RSD < 5 %. The method was successfully applied to different types of extracts of the plant. Therefore, it is concluded from the study that the method is simple, linear, selective, repeatable and reproducible. Moreover, the method can be applied for the standardization of extracts/exudates of the plant. © 2014, Chemical Publishing Co. All rights reserved.


PubMed | The Islaima University of Bahawalpur, University of South Asia of Pakistan, Federal University of Paraiba and University of Punjab
Type: Journal Article | Journal: Pakistan journal of pharmaceutical sciences | Year: 2016

The aim of current research was to develop a water-in-oil emulsion containing grape seed extract for application in cosmeceuticals. Finally grinded dried grape seeds powder was extracted with hydro alcoholic mixture. Emulsions consisting of different concentrations of cetyl dimethicone (Abile EM90), the nonionic emulsifier, liquid paraffin as oily phase and water as aqueous phase were developed. Color, odor, pH, viscosity, liquefaction, phase separation, centrifugation and thermal stability of the formulated emulsions were observed at various storage temperatures i.e. 80.5C, 250.5C, 400.5C and 40C0.5C with 70% RH. The stable formulation consist of 16% mineral oil, 4% of ABIL EM 90(), 4% grape seeds extract, 1% rose oil and 75% distilled water. All the results derived from this study showed good stability over the three months study period which indicates w/o emulsion can be used as carrier of 4% grape seeds extract to enhance desired effects when applied topically.

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