Seville, Spain

University of Seville

www.us.es/eng
Seville, Spain

The University of Seville is a university in Seville, Spain. Founded under the name of Colegio Santa María de Jesús in 1505, it has a present student body of over 65,000, and is one of the top-ranked universities in the country. Seville is the 2000-year-old artistic, cultural, and financial capital of Andalusia in southern Spain; it is situated on the plain of the River Guadalquivir. Wikipedia.

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Patent
University of Seville and Biomedal S.L. | Date: 2017-05-17

The invention relates to a method for detecting and quantifying gluten peptides, resistant to gastrointestinal digestion, in human fluids, preferably urine. The presence or absence of the gluten peptides is monitored by immunological tests based on specific antibodies against same.


The invention relates to a method for producing simple and compound emulsions having micrometre-sized, controllable diameters and coatings, using a device formed by elements having characteristic dimensions of the order of a millimetre. The emulsions are produced using the suction produced by the flow of a viscous liquid through the section of a millimetre-sized capillary tube. According to a parametric analysis, the liquid or the pair of liquids to be emulsified form a simple or compound steady capillary jet of micrometre diameter, by the action of the co-flow of the emulsifying liquid and the favourable pressure gradient produced. The jet breaks because of capillary instability, forming simple or compound monodisperse micro-drops. The invention disclosed in this description can be used in industrial sectors where the production of simple and compound, monodisperse, homogeneous emulsions having micrometric-sized, controllable diameters and coatings is an essential part of the process.


The method comprises placing the powders in an electrically isolating mold, applying a pressure to the powders between 100 and 500MPa and applying to the powders a sintering current at a sintering voltage during a sintering time, for sintering the powders. Before applying the sintering current density, applying an activation current density lower than the sintering current density at an activation voltage greater than the sintering voltage during an activation time lower than the sintering time, to reduce the electrical resistance of the powders.


Patent
University of Seville and Biomedal S.L. | Date: 2015-07-09

The present invention discloses a process for detecting and quantifying gluten peptides resistant to gastrointestinal digestion in human body fluids, preferably urine. The presence or absence of gluten peptides is controlled by immunological assays based on specific gluten peptide antibodies directed thereagainst.


A method of molecular self-assembly is disclosed using two interacting streams. A first stream of a dope solution of polymer molecules is extruded out of the nozzle of a capillary. The nozzle is surrounded by a focusing fluid which is miscible with the dope solution. The interaction between the jet of dope solution and surrounding focusing fluid creates hydrodynamic stretching and allows for extracting solvent from the dope solution. Concentrated polymers within the solution at stretched regions of the jet interact, self-assemble and may form a fiber or thread which can be wound onto a mandrel.


Patent
University of Seville | Date: 2017-09-27

The invention relates to the synthesis and application of gold catalysts supported in mixed CuO/ZnO/Al_(2)O_(3) oxides prepared on the basis of their corresponding solids with a hydrotalcite structure as catalysts in the displacement reaction of gas from water, for use in fuel processors coupled to fuel cells..


Sanchez-Romero M.A.,University of Seville | Casadesus J.,University of Seville
Proceedings of the National Academy of Sciences of the United States of America | Year: 2014

Antibiotic-resistant isolates of Salmonella enterica were selected on plates containing lethal concentrations of rifampicin, kanamycin, and nalidixic acid. The stability of the resistance phenotype was scored after nonselective growth. Rifampicin-resistant (Rifr) isolates were stable, suggesting that they had arisen by mutation. Mutations in the rpoB gene were detected indeed in Rifr mutants. In contrast, a fraction of kanamycin-resistant (Kmr) and nalidixic acid-resistant (Nal r) isolates showed reduced resistance after nonselective growth, suggesting that mechanisms other than mutation had contributed to bacterial survival upon lethal selection. Single-cell analysis revealed heterogeneity in expression of the porin gene ompC, and subpopulation separation provided evidence that reduced ompC expression confers adaptive resistance to kanamycin. In the case of Nalr isolates, mutations in the gyrA gene were present in most nalidixic acid-resistant isolates. However, the efflux pump inhibitor Phe-Arg-β-naphtylamide (PAβN) reduced the level of resistance in Nalr mutants, indicating that active efflux contributes to the overall level of nalidixic acid resistance. Heterogeneous efflux pump activity was detected in single cells and colonies, and a correlation between high efflux and increased resistance to nalidixic acid was found. These observations suggest that fluctuations in the expression and the activity of critical functions of the bacterial cell, alone or combined with mutations, can contribute to adaptive resistance to antibiotics.


Cabello A.,University of Seville
Physical Review Letters | Year: 2013

We show that the maximum quantum violation of the Klyachko-Can- Binicioǧlu-Shumovsky (KCBS) inequality is exactly the maximum value satisfying the following principle: The sum of probabilities of pairwise exclusive events cannot exceed 1. We call this principle "global exclusivity," since its power shows up when it is applied to global events resulting from enlarged scenarios in which the events in the inequality are considered jointly with other events. We identify scenarios in which this principle singles out quantum contextuality, and show that a recent proof excluding nonlocal boxes follows from the maximum violation imposed by this principle to the KCBS inequality. © 2013 American Physical Society.


Obstructive sleep apnea (OSA) is a risk factor for cardiovascular death in men, but whether it is also a risk factor in women is unknown. To investigate whether OSA is a risk factor for cardiovascular death in women and assess whether continuous positive airway pressure (CPAP) treatment is associated with a change in risk. Prospective, observational cohort study. 2 sleep clinics in Spain. All women consecutively referred for suspected OSA between 1998 and 2007. Every woman had a diagnostic sleep study. Women with an apnea-hypopnea index (AHI) less than 10 were the control group. Obstructive sleep apnea was diagnosed when the AHI was 10 or higher (classified as mild to moderate [AHI of 10 to 29] or severe [AHI ≥30]). Patients with OSA were classified as CPAP-treated (adherence ≥4 hours per day) or untreated (adherence <4 hours per day or not prescribed). Participants were followed until December 2009. The end point was cardiovascular death. 1116 women were studied (median follow-up, 72 months [interquartile range, 52 to 88 months]). The control group had a lower cardiovascular mortality rate (0.28 per 100 person-years [95% CI, 0.10 to 0.91]) than the untreated groups with mild to moderate OSA (0.94 per 100 person-years [CI, 0.10 to 2.40]; P = 0.034) or severe OSA (3.71 per 100 person-years [CI, 0.09 to 7.50]; P < 0.001). Compared with the control group, the fully adjusted hazard ratios for cardiovascular mortality were 3.50 (CI, 1.23 to 9.98) for the untreated, severe OSA group; 0.55 (CI, 0.17 to 1.74) for the CPAP-treated, severe OSA group; 1.60 (CI, 0.52 to 4.90) for the untreated, mild to moderate OSA group; and 0.19 (CI, 0.02 to 1.67) for the CPAP-treated, mild to moderate OSA group. The study was observational and not randomized, and OSA was diagnosed by 2 different methods. Severe OSA is associated with cardiovascular death in women, and adequate CPAP treatment may reduce this risk. None.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: ICT-26-2016 | Award Amount: 5.31M | Year: 2017

MULTIDRONE aims to develop an innovative, intelligent, multi-drone platform for media production to cover outdoor events, which are typically held over wide areas (at stadium/city level). The 4-10 drone team, to be managed by the production director and crew, will have: a) increased decisional autonomy, by minimizing production crew load and interventions and b) improved robustness, security and safety mechanisms (e.g., embedded flight regulation compliance, enhanced crowd avoidance, autonomous emergency landing, communications security), enabling it to carry out its mission even against adverse conditions or crew inaction and to handle emergencies. Such robustness is particularly important, as the drone team has to operate close to crowds and may face an unexpected course of events and/or environmental hazards. Therefore, it must be contextually aware and adaptive with improved perception of crowds, individual people and other hazards. As this multi-actor system will be heterogeneous, consisting of multiple drones and the production crew, serious human-in-the-loop issues will be addressed to avoid operator overload, with the goal of maximizing shooting creativity and productivity, whilst minimizing production costs. Overall, MULTIDRONE will boost research on multiple-actor systems by proposing novel multiple-actor functionalities and performance metrics. Furthermore, the overall multidrone system will be built to serve identified end user needs. Specifically, innovative, safe and fast multidrone audiovisual shooting will provide a novel multidrone cinematographic shooting genre and new media production techniques that will have a large impact on the financially important EU broadcasting/media industry. It will boost production creativity by allowing the creation of rich/novel media output formats, improving event coverage, adapting to event dynamics and offering rapid reaction speed to unexpected events.

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