Rennes, France
Rennes, France

The University of Rennes 1 is one of the two main universities in the city of Rennes, France. It is under the Academy of Rennes. It specializes in science, technology, law, economy, management and philosophy. The University of Rennes 1 has been in existence since 1969, but its heritage stems back to the days of the Breton university founded in 1461. There are currently about 26,000 students enrolled, with about 1800 members of teaching staff and 1700 other staff members employed by the university. Wikipedia.


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Patent
University of Rennes 1 and French National Center for Scientific Research | Date: 2015-04-17

The invention relates to a material consisting of a preparation made from a mixture of ferrocene and an inert flameproof material such as plaster, the material being presented in the form of granules and being suitable for spreading over a hydrocarbon fire in a simple and rapid manner such that, under the effect of the heat from the fire, the ferrocene contained in the granulated material is diffused progressively and homogeneously in a vapour phase over the base of the flames, so as to optimise the combustion of the hydrocarbon and to reduce the emission of smoke and unwanted particles.


Patent
University of Rennes 1, French National Center for Scientific Research, French Institute for Research in Computer Science, Automation, French Institute of Health and Medical Research | Date: 2015-04-16

A computer-implemented method of characterizing molecular diffusion within a body from a set of diffusion-weighted magnetic resonance signals by computing a weighted average of a plurality of multi-compartment diffusion models comprises a same number of compartments, fitted to a set of diffusion-weighted magnetic resonance signals, the weighted average being computed using weights representative of a performance criterion of each of the models; wherein each of the multi-compartment diffusion models comprises a different number of subsets of compartments, the compartments of a same subset being identical to each other.


Patent
French National Center for Scientific Research and University of Rennes 1 | Date: 2015-03-23

A method is proposed for driving a plurality of functional modules included in a multi-wavelength microscopy imaging device. The device includes at least one first functional module and a second functional module, adapted respectively to performing a first function and a second function. The method includes at least one iteration of the acts of: sending a first driving signal to the second functional module when the first functional module has performed said first function; the second functional module triggers the function upon reception of the first driving signal; sending a second driving signal to the first functional module when the second functional module has performed said second function; the first functional module triggers said first function upon reception of the second driving signal.


Patent
University of Rennes 1 and French National Center for Scientific Research | Date: 2015-03-17

A Frequency-tunable and slot-fed planar antenna is proposed. The antenna includes resonant patch, a first dielectric layer, a ground plane having a first slot for each linear polarization, a second dielectric layer and a transmission line having, for each first slot, an end strand extending beneath the first slot. The antenna is frequency tunable for each linear polarization through at least one variable capacitance element. The matching of the antenna varies, for each linear polarization, as a function of a bias voltage applied to the variable capacitance element(s). The antenna includes, for each linear polarization, at least one second slot extending along the first slot. The end strand of the transmission line extends between the first slot and second slots. The at least one second slot creates an additional resonance.


Patent
French National Center for Scientific Research and University of Rennes 1 | Date: 2015-07-08

A method of manufacturing a sulfide-based ceramic element, such as a transparent infrared optical element, comprises the steps of: synthesizing a sulfide powder; and sintering the powder to form the ceramic element; wherein the step of synthesizing the sulfide powder is performed by combustion in an aqueous solution, the solution comprising water as its only solvent, or containing water as its main solvent and at most 10%, and preferably at most 1% of the overall solvent mass, of one or more combustible solvents. The sulfide powder may be chosen, in particular, among ZnS, BaLa_(2)S_(4), CaLa_(2)S_(4).


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SC1-PM-22-2016 | Award Amount: 15.59M | Year: 2016

ZIKAlliance is a multidisciplinary project with a global One Health approach, built: on a multi-centric network of clinical cohorts in the Caribbean, Central & South America; research sites in countries where the virus has been or is currently circulating (Africa, Asia, Polynesia) or at risk for emergence (Reunion Island); a strong network of European and Brazilian clinical & basic research institutions; and multiple interfaces with other scientific and public health programmes. ZIKAlliance will addrees three key objectives relating to (i) impact of Zika virus (ZIKV) infection during pregnancy and short & medium term effects on newborns, (ii) associated natural history of ZIKV infection in humans and their environment in the context of other circulating arboviruses and (iii) building the overall capacity for preparedness research for future epidemic threats in Latin America & the Caribbean. The project will take advantage of large standardised clinical cohorts of pregnant women and febrile patients in regions of Latin America and the Caribbean were the virus is circulating, expanding a preexisting network established by the IDAMS EU project. I will also benefit of a very strong expertise in basic and environmental sciences, with access to both field work and sophisticated technological infrastructures to characterise virus replication and physiopathology mechanisms. To meet its 3 key objectives, the scientific project has been organised in 9 work packages, with WP2/3 dedicated to clinical research (cohorts, clinical biology, epidemiology & modeling), WP3/4 to basic research (virology & antivirals, pathophysiology & animal models), WP5/6 to environmental research (animal reservoirs, vectors & vector control) , WP7/8 to social sciences & communication, and WP9 to management. The broad consortium set-up allow gathering the necessary expertise for an actual interdisciplinary approach, and operating in a range of countries with contrasting ZIKV epidemiological status.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: PHC-30-2015 | Award Amount: 5.00M | Year: 2016

Valvular Heart Disease currently affects 2.5% of the population, but is overwhelmingly a disease of the elderly and consequently on the rise. It is dominated by two conditions, Aortic Stenosis and Mitral Regurgitation, both of which are associated with significant morbidity and mortality, yet which pose a truly demanding challenge for treatment optimisation. By combining multiple complex modelling components developed in recent EC-funded research projects, a comprehensive, clinically-compliant decision-support system will be developed to meet this challenge, by quantifying individualised disease severity and patient impairment, predicting disease progression, ranking the effectiveness of alternative candidate procedures, and optimising the patient-specific intervention plan. This algorithmically-driven process will dramatically improve outcomes and consistency across Europe in this fast-growing patient group, maximising individual, societal and economic outcomes.


Grant
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: PHC-18-2015 | Award Amount: 8.19M | Year: 2016

Liver cancer in the paediatric population is rare with an incidence approximately 1-1.5 per million population. The commonest tumour seen in the childhood population is hepatoblastoma (HB), usually seen in young children and infants. Much rarer (about 10% of paediatric liver cancers) is hepatocellular carcinoma (HCC), usually seen in the teenage population and sometimes associated with underlying cirrhotic liver diseases. The ChiLTERN project relates to topic PHC 18 establishing effectiveness of health care interventions in the paediatric population. The ChiLTERN project builds on a unique opportunity to undertake a comprehensive research programme linked to an ambitious global partnership which will see the single largest clinical trial (the Paediatric Hepatic International Tumour Trial - PHITT) ever undertaken in this population of patients, with several randomised questions in six subgroups of patients. ChiLTERN will allow us to move towards an era of personalised therapy in which each patient will receive the correct amount of chemotherapy and will undergo has the best surgical operation (surgical resection or liver transplant). By using both clinical and biological information, we can assign patients more accurately to risk groups based on their survival. Using genetic tests and biomarkers, we will determine those children who may be at risk of developing long term side effects (deafness, heart failure, kidney damage). In addition, biomarkers will allow us to monitor during therapy and detect toxicities early before serious damage is done so that we can adapt treatment and prevent these problems. Finally, we will be using imaging technology tools which will help our surgeons plan liver operations more safely and effectively. Ultimately ChiLTERN will allow us to cure more children with liver cancer, expose fewer children to toxic chemotherapy and ensure their surgery is both effective and safe.


Using the clinical and signal data (cardiac and respiratory traces, video quantification of movement and sound) from a large cohort of hospitalised newborn and pregnant women recordings Digi-NewB aims to propose a new decision support system (DSS). This DSS will assist the clinician in his decision-making through non-invasive monitoring of sepsis risk and of cardio-respiratory and neurobehavioral maturations. The objective is to reduce mortality, morbidity and health costs for the hospitalised newborns. More precisely the proposal consist in: i) implementing a large targeted prospective multicentre neonatal cohort, recruited in six university hospitals, ii) identifying the most relevant composite indices to be included in the DSS iii) validating DSS acceptability and usability in the clinical management of the identified complex situations. To achieve these goals, a consortium has been constituted, under the coordination of a paediatric clinical network (GCS HUGO-France), with two SME (Voxygen-France and Syncrophi-Ireland) and four university groups with multidisciplinary expertise: in signal processing (INESC-Portugal and LTSI-UR1 France), in multivariate analyses (TUT-Finland) and in user centred design approach (NUIG-Ireland). The proposed new class of monitoring will lead to development of novel preventive and therapeutic strategies to counteract late diagnosis of sepsis and inappropriate evaluation of maturity. This will result in i) a decrease in sepsis related death and morbidity through early and personalized prescription of antibiotics, ii) a decrease in the risks of severe cardio-respiratory events and inadequate prolongation of hospitalization iii) a decrease in health costs. At the end of the Digi-NewB program the opportunity to productise the results will be evaluated. It would be a strong next generation product which would secure a good market position. Feasibly development work will be carried out by the SME industrial partners.


Grant
Agency: European Commission | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2016 | Award Amount: 4.02M | Year: 2016

SUPercontinuum broadband light sources covering UV to IR applications (SUPUVIR) will combine the efforts of 6 academic and 4 non-academic beneficiaries to train 15 ESRs for the growing industry within SC broadband light sources, giving them extensive knowledge in silica and soft-glass chemistry, preform design and fibre drawing, linear and nonlinear fibre and waveguide characterization, nonlinear fibre optics, SC modelling, SC system design, patent protection, and in-depth knowledge of a broad range of the main applications of SC high-power broadband light sources. The strong blend of academic and non-academic sectors in the consortium will give the ESRs a unique chance to develop a wide set of technical and transferrable skills, thus preparing them for long-time employment in the sector (academic or industry). Scientifically, SUPUVIR aims at solving current challenges preventing SC light sources from taking over key market shares or from being used for cutting-edge research . Specifically the objectives are to reduce noise and increase pulse energy of SC modules, as well as investigate SC generation in emerging wavelength regimes (UV and mid-IR) including fabrication of novel fibres and waveguides, and finally using SC sources for applications as to gain valuable knowledge of application requirements. This research and development will give improved SC sources and SC spectra enabling new science and applications for optical imaging, spectroscopy, sensing and control, e.g. optical coherence tomography, IR multimodal spectroscopy, confocal and fluorescence microscopy, photoacoustic imaging and food quality control.

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