Rennes, France
Rennes, France

The University of Rennes 1 is one of the two main universities in the city of Rennes, France. It is under the Academy of Rennes. It specializes in science, technology, law, economy, management and philosophy. The University of Rennes 1 has been in existence since 1969, but its heritage stems back to the days of the Breton university founded in 1461. There are currently about 26,000 students enrolled, with about 1800 members of teaching staff and 1700 other staff members employed by the university. Wikipedia.


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Patent
University of Rennes 1 and French National Center for Scientific Research | Date: 2015-04-17

The invention relates to a material consisting of a preparation made from a mixture of ferrocene and an inert flameproof material such as plaster, the material being presented in the form of granules and being suitable for spreading over a hydrocarbon fire in a simple and rapid manner such that, under the effect of the heat from the fire, the ferrocene contained in the granulated material is diffused progressively and homogeneously in a vapour phase over the base of the flames, so as to optimise the combustion of the hydrocarbon and to reduce the emission of smoke and unwanted particles.


Grant
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: ICT-04-2015 | Award Amount: 3.89M | Year: 2016

Increasing performance and reducing costs, while maintaining safety levels and programmability are the key de-mands for embedded and cyber-physical systems in European domains, e.g. aerospace, automation, and automotive. For many applications, the necessary performance with low energy consumption can only be provided by customized computing platforms based on heterogeneous many-core architectures. However, their parallel programming with time-critical embedded applications suffers from a complex toolchain and programming process. ARGO (WCET-Aware PaRallelization of Model-Based Applications for HeteroGeneOus Parallel Systems) will ad-dress this challenge with a holistic approach for programming heterogeneous multi- and many-core architectures using automatic parallelization of model-based real-time applications. ARGO will enhance WCET-aware automatic parallelization by a cross-layer programming approach combining automatic tool-based and user-guided parallelization to reduce the need for expertise in programming parallel heterogeneous architectures. The ARGO approach will be assessed and demonstrated by prototyping comprehensive time-critical applications from both aerospace and industrial automation domains on customized heterogeneous many-core platforms. The challenging research and innovation action will be achieved by the unique ARGO consortium that brings together industry, leading research institutes and universities. High class SMEs such as Recore Systems, Scilab Enterprises and AbsInt will contribute their diverse know-how in heterogeneous many-core technologies, model-based design environments and WCET calculation. The academic partners will contribute their outstanding expertise in code transformations, automatic parallelization and system-level WCET analysis.


Grant
Agency: Cordis | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2015-ETN | Award Amount: 3.91M | Year: 2016

The SUBITOP ETN is a framework for training and career development of young researchers in Geodynamics, Geophysics, Geology and Geomorphology. It has a scientific focus on the dynamics of continental margins where tectonic plates are recycled through subduction. Subduction processes have shaped and govern many aspects of the topography of Europe, and other continents, and they determine the patterns and intensity of geological hazards such as earthquakes, volcanic activity and landsliding. The Training Network will imbue 15 young scientists with the ability to address the links between the geological processes within subduction zones and the processes that impact the Earths surface above, using a comprehensive range of modelling and observation techniques and exploiting the full diversity of active and ancient subduction systems within Europe. SUBITOP fuses research and training at ten leading centres of the Earth Sciences in Europe and forges partnerships with 15 companies for its fellows, with participants in eight countries. It will train Early Stage Researchers (ESR) through a structured programme of cross-disciplinary, collaborative research, and integrated skills and outreach activities. This experience-based training is centred on PhD projects, covering a spectrum of topics from the deep mechanics of subduction zones to the erosion of their uplifted topography. Together the projects probe the functioning of the subduction system in its entirety, and they are welded together by shared techniques, study sites and data sets. Through their projects, the ESRs will acquire skills in modelling and observation of coupled processes in complex geological systems. SUBITOP will also impart essential communication, outreach and career management skills, and first-hand experience of the private sector through project-specific secondments and co-supervision by industry partners, and embed its ESRs in the active TOPO-Europe research community.


Grant
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: SC1-PM-22-2016 | Award Amount: 15.59M | Year: 2016

ZIKAlliance is a multidisciplinary project with a global One Health approach, built: on a multi-centric network of clinical cohorts in the Caribbean, Central & South America; research sites in countries where the virus has been or is currently circulating (Africa, Asia, Polynesia) or at risk for emergence (Reunion Island); a strong network of European and Brazilian clinical & basic research institutions; and multiple interfaces with other scientific and public health programmes. ZIKAlliance will addrees three key objectives relating to (i) impact of Zika virus (ZIKV) infection during pregnancy and short & medium term effects on newborns, (ii) associated natural history of ZIKV infection in humans and their environment in the context of other circulating arboviruses and (iii) building the overall capacity for preparedness research for future epidemic threats in Latin America & the Caribbean. The project will take advantage of large standardised clinical cohorts of pregnant women and febrile patients in regions of Latin America and the Caribbean were the virus is circulating, expanding a preexisting network established by the IDAMS EU project. I will also benefit of a very strong expertise in basic and environmental sciences, with access to both field work and sophisticated technological infrastructures to characterise virus replication and physiopathology mechanisms. To meet its 3 key objectives, the scientific project has been organised in 9 work packages, with WP2/3 dedicated to clinical research (cohorts, clinical biology, epidemiology & modeling), WP3/4 to basic research (virology & antivirals, pathophysiology & animal models), WP5/6 to environmental research (animal reservoirs, vectors & vector control) , WP7/8 to social sciences & communication, and WP9 to management. The broad consortium set-up allow gathering the necessary expertise for an actual interdisciplinary approach, and operating in a range of countries with contrasting ZIKV epidemiological status.


Grant
Agency: Cordis | Branch: H2020 | Program: MSCA-RISE | Phase: MSCA-RISE-2015 | Award Amount: 1.85M | Year: 2016

Achieving a sustainable development trajectory in Amazonia is one of the key challenges facing Brazil, and is also an important international concern. ODYSSEA assembles an internationally renowned European and Brazilian multidisciplinary and intersectoral team. We aim to produce fundamental science and tools in order to build an innovative multi-and interdisciplinary observatory to monitor and assess dynamic interactions between Amazon societies and their environments. This observatory will serve as a basis for policy development that integrates social, environmental, political-economic and human health dimensions. Our methodology puts the society at the heart of the observatorys building process, engaging stakeholders and decision makers in the research to favour advancement of their objectives and commitment to sustainable development issues. Building on knowledge framed around ongoing bilateral projects, ODYSSEA brings together several independent networks of international and Brazilian researchers which all have long-term experiences in the Amazon of environmental and social research, each with their own expert skill-sets. We expect significant advances in our understanding of the different feedbacks and linkages between the panoply of pressures exerted on the environment, the factors determining the vulnerability of local populations to environmental shocks and in the evaluation of governance and institutional arrangements aiming at promoting adaptation. We aim to enhance the capacity of Brazilian institutions to assess and reduce the vulnerability of populations in Amazonia. ODYSSEA will help unify an increasing number of bilateral arrangements for research and innovation between individual European countries and Brazil. Whilst these connections are proving fruitful in their own right there is a largely untapped opportunity to upscale the intensity and diversity of connections between Europe and Brazil on all levels of education, research and development.


Grant
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: PHC-30-2015 | Award Amount: 5.00M | Year: 2016

Valvular Heart Disease currently affects 2.5% of the population, but is overwhelmingly a disease of the elderly and consequently on the rise. It is dominated by two conditions, Aortic Stenosis and Mitral Regurgitation, both of which are associated with significant morbidity and mortality, yet which pose a truly demanding challenge for treatment optimisation. By combining multiple complex modelling components developed in recent EC-funded research projects, a comprehensive, clinically-compliant decision-support system will be developed to meet this challenge, by quantifying individualised disease severity and patient impairment, predicting disease progression, ranking the effectiveness of alternative candidate procedures, and optimising the patient-specific intervention plan. This algorithmically-driven process will dramatically improve outcomes and consistency across Europe in this fast-growing patient group, maximising individual, societal and economic outcomes.


Grant
Agency: Cordis | Branch: H2020 | Program: RIA | Phase: PHC-18-2015 | Award Amount: 8.19M | Year: 2016

Liver cancer in the paediatric population is rare with an incidence approximately 1-1.5 per million population. The commonest tumour seen in the childhood population is hepatoblastoma (HB), usually seen in young children and infants. Much rarer (about 10% of paediatric liver cancers) is hepatocellular carcinoma (HCC), usually seen in the teenage population and sometimes associated with underlying cirrhotic liver diseases. The ChiLTERN project relates to topic PHC 18 establishing effectiveness of health care interventions in the paediatric population. The ChiLTERN project builds on a unique opportunity to undertake a comprehensive research programme linked to an ambitious global partnership which will see the single largest clinical trial (the Paediatric Hepatic International Tumour Trial - PHITT) ever undertaken in this population of patients, with several randomised questions in six subgroups of patients. ChiLTERN will allow us to move towards an era of personalised therapy in which each patient will receive the correct amount of chemotherapy and will undergo has the best surgical operation (surgical resection or liver transplant). By using both clinical and biological information, we can assign patients more accurately to risk groups based on their survival. Using genetic tests and biomarkers, we will determine those children who may be at risk of developing long term side effects (deafness, heart failure, kidney damage). In addition, biomarkers will allow us to monitor during therapy and detect toxicities early before serious damage is done so that we can adapt treatment and prevent these problems. Finally, we will be using imaging technology tools which will help our surgeons plan liver operations more safely and effectively. Ultimately ChiLTERN will allow us to cure more children with liver cancer, expose fewer children to toxic chemotherapy and ensure their surgery is both effective and safe.


This proposal aims to develop a combination of a chirped-pulse (sub)mm-wave rotational spectrometer with uniform supersonic flows generated by expansion of gases through Laval nozzles and apply it to problems at the frontiers of reaction kinetics. The CRESU (Reaction Kinetics in Uniform Supersonic Flow) technique, combined with laser photochemical methods, has been applied with great success to perform research in gas-phase chemical kinetics at low temperatures, of particular interest for astrochemistry and cold planetary atmospheres. Recently, the PI has been involved in the development of a new combination of the revolutionary chirped pulse broadband rotational spectroscopy technique invented by B. Pate and co-workers with a novel pulsed CRESU, which we have called Chirped Pulse in Uniform Flow (CPUF). Rotational cooling by frequent collisions with cold buffer gas in the CRESU flow at ca. 20 K drastically increases the sensitivity of the technique, making broadband rotational spectroscopy suitable for detecting a wide range of transient species, such as photodissociation or reaction products. We propose to exploit the exceptional quality of the Rennes CRESU flows to build an improved CPUF instrument (only the second worldwide), and use it for the quantitative determination of product branching ratios in elementary chemical reactions over a wide temperature range (data which are sorely lacking as input to models of gas-phase chemical environments), as well as the detection of reactive intermediates and the testing of modern reaction kinetics theory. Low temperature reactions will be initially targeted; as it is here that there is the greatest need for data. A challenging development of the technique towards the study of high temperature reactions is also proposed, exploiting existing expertise in high enthalpy sources.


Using the clinical and signal data (cardiac and respiratory traces, video quantification of movement and sound) from a large cohort of hospitalised newborn and pregnant women recordings Digi-NewB aims to propose a new decision support system (DSS). This DSS will assist the clinician in his decision-making through non-invasive monitoring of sepsis risk and of cardio-respiratory and neurobehavioral maturations. The objective is to reduce mortality, morbidity and health costs for the hospitalised newborns. More precisely the proposal consist in: i) implementing a large targeted prospective multicentre neonatal cohort, recruited in six university hospitals, ii) identifying the most relevant composite indices to be included in the DSS iii) validating DSS acceptability and usability in the clinical management of the identified complex situations. To achieve these goals, a consortium has been constituted, under the coordination of a paediatric clinical network (GCS HUGO-France), with two SME (Voxygen-France and Syncrophi-Ireland) and four university groups with multidisciplinary expertise: in signal processing (INESC-Portugal and LTSI-UR1 France), in multivariate analyses (TUT-Finland) and in user centred design approach (NUIG-Ireland). The proposed new class of monitoring will lead to development of novel preventive and therapeutic strategies to counteract late diagnosis of sepsis and inappropriate evaluation of maturity. This will result in i) a decrease in sepsis related death and morbidity through early and personalized prescription of antibiotics, ii) a decrease in the risks of severe cardio-respiratory events and inadequate prolongation of hospitalization iii) a decrease in health costs. At the end of the Digi-NewB program the opportunity to productise the results will be evaluated. It would be a strong next generation product which would secure a good market position. Feasibly development work will be carried out by the SME industrial partners.


Grant
Agency: Cordis | Branch: H2020 | Program: MSCA-ITN-ETN | Phase: MSCA-ITN-2016 | Award Amount: 4.02M | Year: 2016

SUPercontinuum broadband light sources covering UV to IR applications (SUPUVIR) will combine the efforts of 6 academic and 4 non-academic beneficiaries to train 15 ESRs for the growing industry within SC broadband light sources, giving them extensive knowledge in silica and soft-glass chemistry, preform design and fibre drawing, linear and nonlinear fibre and waveguide characterization, nonlinear fibre optics, SC modelling, SC system design, patent protection, and in-depth knowledge of a broad range of the main applications of SC high-power broadband light sources. The strong blend of academic and non-academic sectors in the consortium will give the ESRs a unique chance to develop a wide set of technical and transferrable skills, thus preparing them for long-time employment in the sector (academic or industry). Scientifically, SUPUVIR aims at solving current challenges preventing SC light sources from taking over key market shares or from being used for cutting-edge research . Specifically the objectives are to reduce noise and increase pulse energy of SC modules, as well as investigate SC generation in emerging wavelength regimes (UV and mid-IR) including fabrication of novel fibres and waveguides, and finally using SC sources for applications as to gain valuable knowledge of application requirements. This research and development will give improved SC sources and SC spectra enabling new science and applications for optical imaging, spectroscopy, sensing and control, e.g. optical coherence tomography, IR multimodal spectroscopy, confocal and fluorescence microscopy, photoacoustic imaging and food quality control.

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