Onkoloski Institute Ljubljana and University of Primorska | Date: 2017-08-16
The present invention relates to an expression plasmid comprising a polynucleotide encoding an IL-12 (Interleukin 12) polypeptide and operably linked thereto a CDKN1A promoter, wherein said expression plasmid does not comprise a selectable marker gene. The expression plasmid can be used for the treatment of cancer.
Agency: European Commission | Branch: H2020 | Program: SGA-CSA | Phase: INNOVATION | Award Amount: 64.82K | Year: 2015
The EC has within its Survey of 2011, carried out on request of DG Enterprise and Industry (DG EI), realized that the main barriers of innovation in the eyes of the SMEs, are lack of financial resources and inability to manage innovation process. Since different understandings of the term Innovation Management System (IMS) have been noted the EC has supported European Committee for Standardization to provide the stakeholders with a unified definition of relevant parts in the IMS. According to this definition the most important parts of IMS include companys innovation processes from idea generation to innovation result, but also leadership, management skills and other enabling factors, like the ability to cooperate with third parties like RD partners, clients, and suppliers. The objective of this project in Slovenia is to enable SMEs to bridge the knowledge gap in innovation management, get aware of shortages and improve their internal innovation management system and/or focus on achieving market value with their inventions. The consortium will achieve this objectives with providing: 1.) Enhancing the Innovation Management Capacity of SMEs. The beneficiaries will receive diagnostic of their innovation system based on the standardized IMProve tool. This will lead to the formation of tailored action plan to improve the SMEs capacity to better manage innovation. 2.) Key Account Managers Facilitators for the H2020 SME Instrument. Key Account Managers will identify and source appropriate lead coaches (from predefined pool of coaches), facilitate linking the SMEs to innovation support services and to support the lead coach in delivering services to the SME. The SME Instrument participants will receive the most appropriate services and support to enhance the probability of successful exploitation of the innovation project and to leave a footprint for the future sustainable growth of these beneficiaries.
Agency: European Commission | Branch: FP7 | Program: CSA-SA | Phase: SiS.2013.1.2-1 | Award Amount: 4.38M | Year: 2014
The proposal responds to the Horizon 2020 challenge called Climate action, resource efficiency and raw materials. In addition, it addresses the second specific challenge of the Mobilising and Mutual Learning Action Plans (MMLAP) topics, listed in the Science in Society call for proposals of the Capacities Work Programme 2013, namely Assessment of sustainable innovation. The projects main objective will be to develop a methodological framework for assessing sustainable innovation and managing multi-disciplinary solutions through public engagement in the RTDI system by ensuring the commitment of a broad spectrum of societal stakeholders into its implementation, including industry, policy-makers, research organisations and academia, civil society organisations and the general public. In achievement to the overall objective of the proposed action, the specific objectives include the development of: - a working definition of sustainable innovation, building on common definitions, academic literature as well as expert advice internal and external to the project consortium; - ways to include general public concerns in assessing the social impact of these innovations on society in consultation workshops. Issues such as participation in the development of innovation, inclusiveness, ethics, gender and open access will be considered in these sessions; - a common understanding of best practices in sustainable innovation management; - a framework for assessment and management of sustainable innovations; - specific policy recommendations on how to improve innovation management and how sustainability considerations can be incorporated into it based on the findings of the assessment framework and public consultations. CASI mobilises 19 partners from 12 EU Member States. Through a network of country correspondents CASI will cover the whole of Europe. The work is structured in 11 work packages, and the mandatory work packages as outlined in the call are included.
Agency: European Commission | Branch: FP7 | Program: CSA-SA | Phase: KBBE.2013.2.3-02 | Award Amount: 4.41M | Year: 2013
In the European Union, Small and Medium Enterprises (SMEs) of the food sector are increasingly under pressure due to developing open markets, increasing demand of standardized and price competitive food products by the consumers, rising importance of large retailers and challenges in obeying governmental regulations. This raises the risk of losing many traditional foods as well as traditional processing techniques which are applied by SMEs using regional raw materials and often have a role in the cultural identity of regions. In urban centers in Europe, groups of consumers are increasingly demanding traditional, local and/or organic food productions as food poisoning cases and the dispute on GMO undermined public confidence on industrial food producing systems. To reach these markets, SMEs of traditional foods must extend their skills in modern as well as competitive marketing and production techniques to comply with existing European regulations and to promote the aspects of their products related to nutrition and health. To support these traditional SMEs, a knowledge transfer network shall be established with the focus on different food product sectors: Grains, fishes, fruits, vegetables and mushrooms. These food sectors are traditional, healthy foodstuffs which are essential for a balanced nutrition. To support traditional SMEs in these food sectors, a European network will interlink researchers, knowledge transfer organizations and associations of SMEs on European, national and region levels. The network will act as a mediator of information about innovations in production and marketing of traditional food, will foster entrepreneurship in the sector of traditional food producers and researchers as well as will develop strategic research and innovation agendas for the traditional food sectors to be competitive on future markets.
University of the Basque Country and University of Primorska | Date: 2016-10-19
Computational procedure for designing a vaccine for a disease that starting:- from a plurality of amino acid S_(1)...S_(k) chains obtained from patients infected with such disease; and,- from a T set of target epitopes, each epitope being an amino acid chain; comprises the steps of:i) obtaining by means of a combinatory optimization method a plurality of amino acid chains as short as possible with respect to the combinatory optimization method used having as sub-chains at least a integer of epitopes of the T set in each one of the S_(i) sequences, having a value such that the length of the resulting chain is long enough for eliciting an immune response, but not too long so as to elicit an autoimmune response;ii) choosing from the plurality of chains obtained in the previous step at least one final immunogen candidate by at least one standard experimental method;iii) developing the vaccine from said immunogen.
Agency: European Commission | Branch: H2020 | Program: SGA-CSA | Phase: WIDESPREAD-1-2014 | Award Amount: 495.62K | Year: 2015
With excellence in research, innovation, and application into economy and society, the new Centre of Excellence, Renewable materials and healthy environments research and innovation centre of excellence (InnoRenew CoE) will improve sustainable building practices by combining the existing concepts with the Restorative Environmental Design (RED) paradigm, which combines sustainable building practices with biophilic design. This will increase the competitive advantages of the affiliated renewable resource-based construction industry, and create innovation and market pull for RED-based materials and products (holistic living environment). Consequently, innovation and market pull for material recovery and higher added value renewable resource based and energy carriers will be initiated. Research and development activities will seek the optimal intersection of performance and sustainability, including economic, environmental and societal indicators. With support and guidance from the advanced partner, Fraunhofer WKI, scientific research and development activities will be transferred profitably and efficiently to the industry and through them to society in the form of innovative new products and processes.
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: ISSI-5-2015 | Award Amount: 3.50M | Year: 2016
STAR BIOS 2 (Structural Transformation to Attain Responsible BIOSciences),coordinated by the University of Tor Vergata (IT), has been designed to respond to the Topic ISSI 5 (Workprogramme Science With And For Society). The general aim of project is that of contributing to the advancement of the Responsible Research and Innovation (RRI) strategy, which underpins Horizon 2020, by promoting 6 Action Plans (APs) oriented to attain a RRI structural change in research institutions from Europe and developing 3 further APs in non-european entities, all active in the field of biosciences. This strategy is geared to cope more in general with one of the main risk, for European research, i.e., its inadequate connection with society, by promoting its increasing alignment, in terms of both process and outcomes, with the needs and values of European society. This entails, in the RRI perspective, an increasing involvement of stakeholders at any level of the research and innovation process. The project has three main focuses: 1) Develop RRI-oriented structural change processes in the already mentioned institutions involved in biosciences research. This aim will be pursued through designing, implementing and evaluating RRI Action Plans. In order to secure the results emerging from the APs, a sustainability strategy will be developed and implemented during the project lifespan. APs will be supported by a central technical assistance and the project will be monitored and assessed. 2) Develop a learning process concerning: a) resistances and barriers to RRI (which are they, how they manifest themselves, which impact they have, etc.); b) key factors favouring or supporting RRI; c) strategic options and RRI-oriented tools. 3) Develop a sustainable model for RRI in biosciences.
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: MSCA-NIGHT-2016 | Award Amount: 158.99K | Year: 2016
Main objectives of the SciFe proposal is to bring researchers to the general public, to inspire youngster to embark on scientific careers, to increase awareness of importance of research and innovation activities, with a view to supporting the public recognition of researchers creating an understanding of the impact of researchers work on citizens daily life. For that purpose the awareness campaign (AC) to convey messages under the slogan Science for Life will be used in 2016 and 2017. On Fridays 30.9.16 and 29.9.17 SciFe events will be organized with renewed programs in festive and fun atmosphere in Ljutomer, Maribor, Breice, Ljubljana, Koper, Izola and Nova Gorica. All SciFe events activities aim at offering the public at large an opportunity to cooperate in fascinating experiments, demonstrations, observations etc., to socialize and have fun with researchers in a relaxed atmosphere. The program is appropriate for public in general, regardless their scientific program and especially designed for youngest. SciFe programs red line is contribution of science to life in various aspects. The European corner will be prepared in the heart of every RN location: the visitors will be offered information on ECs various actions and programs, EU material, the Charter and the Code, information how young people can become researchers and Framework Program witnesss experiences. Intensive awareness campaign is designed according to its main target. The rich communication mix includes active engagement of the young people through the public call targeting primary and secondary schools. Last but not least, the impact assessment will focus to measure the success and the impact of SciFe activities. All that will be achieved through consortium management of all WPs and harmonised communication mix with general public which takes into account existing recognition of the RN event in certain region and its number of inhabitants.
Agency: European Commission | Branch: H2020 | Program: RIA | Phase: SFS-14a-2014 | Award Amount: 5.35M | Year: 2016
The OLEUM project will generate innovative, more effective and harmonized analytical solutions to detect and fight the most common and emerging frauds and to verify the overall quality of olive oils (OOs). By a core group of 20 partners from 15 countries OLEUM will undertake RESEARCH ACTIVITIES based on the development of IMPROVED and NEW ANALYTICAL METHODS by targeted and omics approaches with the aim: i) to detect new markers of the soft deodorization process; ii) to discover illegal blends between OOs and other vegetable oils; iii) to control OO quality (e.g. freshness); iv) to improve the organoleptic assessment with a Quantitative Panel Test, based on current official methods, and supported by tailored reference materials for better calibration of the sensory panels coupled with rapid screening tools to facilitate the work of the panelists. The most promising OLEUM solutions will be subjected to VALIDATION in conformity with internationally agreed standards by peer laboratories. OLEUM will recreate a realistic deodorization scenario by producing tailored, soft deodorized OOs by lab-scale and up-scaled pilot plants to apply analytical solutions to known samples. Substantial KNOWLEDGE and TECHNOLOGY TRANSFER activities will be envisaged to aid in implementation of: a) a web-based easily-accessible, scalable and constantly updated OLEUM DATABANK, containing all the information from OLEUM research and other reliable international sources, will be available for download data and spectra and to help achieve satisfactory harmonization of analytical approaches among control laboratories; b) the OLEUM NETWORK of relevant OOs stakeholders to maximize the impact of proposed analytical solutions. Finally, a robust dissemination strategy by the OLEUM project aimed at effectively sharing results with all stakeholders in the OO supply chain has the potential to improve consumer and market confidence, and preserve the image of OOs on a global scale.
Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: KBBE.2012.1.4-09 | Award Amount: 3.12M | Year: 2012
The project will deliver a coherent and innovative evaluation of competitiveness of European food chains by integrating various new approaches. Based on this, the research results allows to deduce a congruent, coherent and consistent set of policy recommendations aiming at improving competitiveness and promoting the Knowledge Based Bio-Economy in Europe. The analysis is conducted along two lines, (1) conception and indicators of competitiveness and (2) its determinants. In the first part a comprehensive definition of competitiveness will be developed by integrating the finding from selected theoretical micro and macro approaches. In this respect the conventional conception will be extended by moving from the industry to the value chain perspective and considering commodities as well as intermediary and final products. This framework constitutes the basis for the empirical analysis, where the EU position on world markets will be discussed in relation to that of major competitors. The second part deals with selected determinants of competitiveness. These include policy intervention and business environment, productivity in agriculture and food processing, the functioning of domestic and international markets, the choice of governance structures as well as innovative activities in food processing. The investigation of each determinant will be innovative and extends the state of the art by deepening the theoretical backgrounds, extending the methodological approaches or applying empirical methods for the first time. The analysis of the determinants will contribute significantly to be better and deeper understanding of competitiveness and the deduction of policy recommendations. Research will be conducted by a team that was constituted according to the needs of the research project. Each partner is a designated expert in his/her area of research. Past co-operations among partners assure that all tasks will be arranged target-oriented in due time.