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Santander de Quilichao, Colombia

The University of Pamplona , is a public, departmental, coeducational research university based primarily in the city of Pamplona, Norte de Santander, Colombia. The university also has two satellite campuses in the department, in the cities of Cúcuta and Villa del Rosario. Wikipedia.

Arana M.,University of Pamplona
Journal of the Acoustical Society of America | Year: 2010

The majority of acoustic impact studies developed over the last 50 years have used a similar acoustic parameter (Leq, Ldn) but the noise mapping methodology has been very uneven. The selection of the measurement points, the measurement periods, or the evaluation indices have not followed a unique criterion. Therefore, it is not possible to compare the sound pollution levels between different cities from those studies, at least in a rigorous sense. Even more, different studies carried out in the same city by different researchers during different years and using different methodologies are not conclusive whether the acoustic pollution increases or decreases. The present paper shows results, with statistical significance, about the evolution of the acoustic pollution obtained for two Spanish cities, Pamplona and Madrid. In both cases, it can be concluded that noise pollution decreases over time (P<0.01). © 2010 Acoustical Society of America.

Herranz G.,University of Pamplona
Zygote | Year: 2014

In the dominant model, monozygotic (MZ) twinning is universally accepted as a post-fertilization event resulting from splitting of the embryo along its first 2 weeks of development. The stage at which splitting occurs determines chorionicity and amnionicity. A short history on how the model was built is presented, stressing the role played by some embryologists, in particular George Corner, in its completion and final success. Strikingly, for more than 60 years no deep criticisms have been raised against the model, which, in virtue of its rational and plausible character, enjoys the status of undisputed truth. At close examination, the embryological support of the model shows some important weak points, particularly when dealing with late splitting. In the author's view, the model not only has contributed to 'suspend' our knowledge on the timing of MZ twinning, but seems indefensible and claims to be substituted. That factor could imply relevant consequences for embryology and bioethics. As an alternative to the model, a new theory to explain the timing of MZ twinning is proposed. It is based on two premises. First, MZ twinning would be a fertilization event. In that case, due to an alteration of the zygote-blastomere transition, the first zygotic division, instead of producing two blastomeres, generates twin zygotes. Second, monochorionicity and monoamnionicity would not depend on embryo splitting, but on fusion of membranes. Some support for this theory can be found in recent embryological advances and also in some explanations of old. © 2013 Cambridge University Press.

Bueno Alastuey M.C.,University of Pamplona
Computer Assisted Language Learning | Year: 2011

This study explored the benefits and drawbacks of synchronous voice-based computer-mediated communication (CMC) in a blended course of English for specific purposes. Quantitative and qualitative data from two groups following the same syllabus, except for the oral component, were compared. Oral tasks were carried out face-to-face with same L1 partners in the control group and through synchronous voice-based CMC with different L1 partners in the experimental group. The analysis included data from general proficiency pre- and post-test scores, oral Power Point presentation grades, students' questionnaires and students' and teachers' diaries. The results showed that achievements were significantly better in the experimental group and that there was also an increase of other positive factors which may effectively contribute both to second language acquisition (SLA) and to solving many of the problems which make speaking skills the weakest skill in foreign language contexts. © 2011 Copyright Taylor and Francis Group, LLC.

Romano A.,Allergy Unit | Torres M.J.,Allergy Service | Castells M.,Harvard University | Sanz M.L.,University of Pamplona | Blanca M.,Allergy Service
Journal of Allergy and Clinical Immunology | Year: 2011

The present article addresses the advances in the diagnosis and management of drug hypersensitivity reactions that were discussed in the 4th Drug Hypersensitivity Meeting held in Rome in April 2010. Such reactions can be classified as immediate or nonimmediate according to the time interval between the last drug administration and onset. Immediate reactions occur within 1 hour, and nonimmediate reactions occur after more than 1 hour. Clinical and immunologic studies suggest that type-I (IgE-mediated) and type-IV (T cell-mediated) pathogenic mechanisms are involved in most immediate and nonimmediate reactions, respectively. In diagnosis prick, patch, and intradermal tests are the most readily available tools. Determination of specific IgE levels is still the most common in vitro method for diagnosing immediate reactions. New diagnostic tools, such as the basophil activation test, the lymphocyte activation test, and enzyme-linked immunospot assays for analysis of the frequency of antigen-specific, cytokine-producing cells, have been developed for evaluating either immediate or nonimmediate reactions. The sensitivity of allergologic tests is not 100%; therefore in selected cases provocation tests are necessary. In the diagnosis of nonallergic hypersensitivity reactions to nonsteroidal anti-inflammatory drugs, the provocation test with the suspected drug still represents the "gold standard." However, there was no consensus regarding the use of this test in subjects with histories of hypersensitivity reactions to 1 (single reactors) or more (multiple reactors) nonsteroidal anti-inflammatory drugs. With regard to management, desensitization allows patients to be treated with irreplaceable chemotherapy agents, such as taxanes, platinum salts, and mAbs, to which they have presented hypersensitivity reactions. Desensitization also permits the use of aspirin in aspirin-sensitive patients undergoing revascularization and in subjects with aspirin-exacerbated respiratory disease. © 2011 American Academy of Allergy, Asthma & Immunology.

Puertas I.,University of Pamplona | Luis C.J.,University of Pamplona
International Journal of Advanced Manufacturing Technology | Year: 2012

Technical or advanced ceramics have achieved a great deal of importance nowadays as a consequence of their outstanding properties, which make them suitable for application to high-resistance dies and tools for drilling, metal forming and structural components, among others. Nevertheless, manufacturing of these materials is difficult and expensive because they are hard-to-machine materials. In this present study, the application of Electrical Discharge Machining (EDM) is explored for the processing of two conductive ceramics: hot-pressed boron carbide (B 4C) and cobalt-bonded tungsten carbide (WC-Co). The main aim of this present study is to analyse the influence of intensity (I), pulse duration (t i), duty cycle (η), open-circuit voltage (U) and dielectric flushing pressure (P) on the quality of these manufactured products. The response variables studied are: surface roughness (Ra), volumetric electrode wear (EW) and material removal rate (MRR). This study has great industrial interest as there seems to be a lack of knowledge of die-sinking EDM of conductive ceramics in comparison with metallic materials. © Springer-Verlag London Limited 2011.

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