Oradea, Romania
Oradea, Romania

The University of Oradea is a public University, located in Oradea, in North-Western Romania.With its 15 faculties, has a total of 123 fields of study for undergraduates and 151 post-graduate specialisation degrees. The University employs 1600 people, of which 1,080 are teaching personnel, and over 21,000 students . Wikipedia.


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Grant
Agency: European Commission | Branch: FP7 | Program: CP-FP | Phase: HEALTH.2010.2.4.5-2 | Award Amount: 7.31M | Year: 2010

The ALLFUN proposal aims at defining the cellular and molecular mechanisms by which ubiquitous airborne or commensal fungi contribute to immune homeostasis and its dysregulation leading to allergy and inflammatory diseases. Breakthroughs in understanding how mucosal homeostasis is established, maintained or disrupted in the presence of fungi should be sources of new therapeutic targets and drugs (i.e. anti-inflammatory, immunomodulatory and anti-infectious molecules). European scientists representing the leading edge of this field are brought together here in a unique synergistic and cross-cutting collaboration that addresses a major medical and economic problem of considerable importance to the health care sector. The study will be centered on yeasts and filamentous fungi known to be associated with a number of inflammatory, autoimmune and allergic diseases. Via a multidisciplinary systems biology study combining fungal genetics, clinical research and animal models in a systems biology approach, integrating traditional wet-lab methods with those of functional genomics, immunomics, allergomics and bioinformatics, the ALLFUN project meets the criteria of the call, the strategic objective of which is to elucidate mechanisms by which infections may lead to aberrant activation of inflammation, the lack of resolution of which is responsible for inflammatory diseases. The anticipated results are highly relevant to society in terms of reducing the burden of mortality and suffering in patients with fungus-related diseases, identifying more accurate biomarkers for immunological disorders, optimizing and possibly reducing the cost of antifungal therapy by association with anti-inflammatory strategies that targets pathogenicity rather than microbial growth, the host-pathogen interface rather than the pathogen. Understanding the spectrum of immunological responses to fungi is perhaps the single most important challenge in the field of medical mycology.


Grant
Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: SSH.2013.5.2-1 | Award Amount: 6.39M | Year: 2014

Using an innovative interdisciplinary approach, MIME will generate an organised body of policy-relevant propositions addressing the full range of questions raised in the call. Our aim is to identify the language policies and strategies that best combine mobility and inclusion. MIME emphasises complementarity between disciplines, and brings together researchers from sociolinguistics, political science, sociology, history, geography, economics, education, translation studies, psychology, and law, who all have longstanding experience in the application of their discipline to language issues. The diverse concepts and methods are combined in an analytical framework designed to ensure their practice-oriented integration. MIME identifies, assesses and recommends measures for the management of trade-offs between the potentially conflicting goals of mobility and inclusion in a multilingual Europe. Rather than taking existing trade-offs as a given, we think that they can be modified, both in symbolic and in material/financial terms, and we argue that this objective can best be achieved through carefully designed public policies and the intelligent use of dynamics in civil society. Several partners have been involved in successful FP6 research, and key advances achieved there will guide the MIME project: languages are viewed as fluid realities in a context of high mobility of people, goods, services, and knowledge, influencing the way in which skills and identities are used and constantly re-shaped. The project integrates these micro-level insights into a macro-level approach to multilingual Europe. MIME results will be made widely available through a creative approach to dissemination, including training modules and the MIME Stakeholder Forum, allowing for sustained dialogue between academics, professional associations and local/regional authorities. The project culminates in a consensus conference where recommendations based on the project findings are adopted.


Grant
Agency: European Commission | Branch: FP7 | Program: CP | Phase: ENERGY-2007-4.3-01 | Award Amount: 7.55M | Year: 2009

GROUND-MED project will demonstrate geothermal heat pump (GSHP) systems for heating and cooling of measured SPF>5,0 in 8 demonstration sites of South Europe. As the SPF is determined not only by the heat pump unit, but by its operating conditions imposed to the heat pump by the ground heat exchanger and the heating/cooling system of the building as well, integrated systems incorporating the following technological solutions will be demonstrated and evaluated: a) new water source heat pumps of improved seasonal efficiency; key technologies include use of the next generation of compressors, heat exchangers and automation; b) borehole heat exchangers and heating/cooling systems operating with minimum temperature difference between them, which also follows the corresponding heating/cooling demand from the building; design aspects, thermal storage and system controls are important; c) minimum power consumption to system components; key parts are the fan-coil and air-handling units. GROUND-MED has a duration of 5 years and a budget of around 7,3 million euros, comprising 25% research and 75% demonstration and other activities. The GROUND-MED consortium comprises 24 organizations mainly from South Europe, including a wide diversity of GSHP actors, such as research and educational institutes, heat pump manufacturers, national and European industrial associations, energy consultants and works contractors.


Micle O.,University of Oradea
Journal of medicine and life | Year: 2012

Oxidative stress in utero-placental tissues plays an important role in the development of placental-related diseases. Maternal hiperhomocysteinemia is associated with placental mediated diseases, such as preeclampsia, spontaneous abortion and placental abruption. The aim of our study is to appreciate the clinical usefulness of the dosage serum homocysteine and malondialdehyde, as an oxidative stress marker, in the pregnancies complicated with risk of abortion or preterm birth. The study was performed at the Obstetric Gynecology Clinical Hospital Oradea from December 2009 until April 2010. It included 18 patients with risk of abortion (group 1), 22 with preterm birth (group 2). The results were compared with a control group composed by 14 healthy pregnant women. Serum homocysteine level was measured by an enzymatic method, on the instrument Hitachi 912, Roche, reagent: Axis-Shield Enzymatic. For proving the oxidative stress we established the level of malondialdehyde using a method with thiobarbituric acid TBA (Kei Satoh 1978) and the level of ceruloplasmin with the Ravin method .Also AST, ALT,CRP, iron, uric acid, urea were assessed.High level of homocysteine in both groups of study in comparison with the control group was found. The concentration of MDA was significantly higher in pregnancies complicated with risk of abortion and preterm birth compared to the control group (p=0.040, p=0.031). Considerable differences of ceruloplasmin concentration between group 1 and group 2 (p=0.045), and between group 2 and control group (p=0.034), was noticed but not any important differences between group 1 and control group (p=0.683). In women with risk of abortion or with preterm birth an oxidative stress and a hyperhomocysteinemia are present.


Secui D.C.,University of Oradea
Energy Conversion and Management | Year: 2014

In this paper a new modified artificial bee colony algorithm (MABC) is proposed to solve the economic dispatch problem by taking into account the valve-point effects, the emission pollutions and various operating constraints of the generating units. The MABC algorithm introduces a new relation to update the solutions within the search space, in order to increase the algorithm ability to avoid premature convergence and to find stable and high quality solutions. Moreover, to strengthen the MABC algorithm performance, it is endowed with a chaotic sequence generated by both a cat map and a logistic map. The MABC algorithm behavior is investigated for several combinations resulting from three generating modalities of the chaotic sequences and two selection schemes of the solutions. The performance of the MABC variants is tested on four systems having six units, thirteen units, forty units and fifty-two thermal generating units. The comparison of the results shows that the MABC variants have a better performance than the classical ABC algorithm and other optimization techniques. © 2014 Elsevier Ltd.


A recent paper was dedicated to find the nearest fuzzy triangular approximations of a fuzzy number by using α-weighted valuations. We prove, by simple examples, that the results of approximations are not always triangular fuzzy numbers and that in fact they are not fuzzy sets. We give a correct solution of the problem of approximation in a more general case, and we study the properties of identity, additivity, translation invariance, scale invariance, and monotonicity of the new approximation operator. © 2010 Springer-Verlag.


Coroianu L.,University of Oradea
Fuzzy Sets and Systems | Year: 2011

In this paper, we prove new distance properties between a fuzzy number and its trapezoidal approximation preserving the expected interval. Then, we find the best Lipschitz constant of the trapezoidal approximation operator preserving the expected interval. Finally, we use this result in finding within a reasonable error the trapezoidal approximation of a fuzzy number preserving the expected interval in the case when the direct formula leads to complex calculations. © 2010 Elsevier B.V. All rights reserved.


Alb Lupa A.,University of Oradea
Computers and Mathematics with Applications | Year: 2011

In the present paper we establish several differential superordinations regarding the new operator RDλ,αn defined by using the generalized Slgean operator Dλnf(z) and Ruscheweyh derivative Rnf(z), RDλ,αn:A→A, RDλ,αnf(z)=(1-α) Rnf(z)+αDλnf(z),z∈U, where n∈N, λ,α<0 and f∈A,A=f∈H(U):f(z)=z+∑ j=2∞ajzj,z∈U. A number of interesting consequences of some of these superordination results are discussed. Relevant connections of some of the new results obtained in this paper with those in earlier works are also provided. © 2010 Elsevier Ltd. All rights reserved.


Dudrik J.,Technical University of Košice | Trip N.-D.,University of Oradea
IEEE Transactions on Industrial Electronics | Year: 2010

An improved soft-switching full-bridge phase-shifted pulsewidth modulation converter using insulated-gate bipolar transistors with a special auxiliary transformer is presented in this paper. Zero-voltage switching for leading leg and zero-current switching for lagging leg switches in the converter are achieved for full-load range from no load to short circuit by adding an active energy recovery clamp and auxiliary circuits. The new significant feature of the converter consists in suppression of circulating current also in short-circuit conditions. The proposed converter is very attractive for applications where short circuit and no load are the normal states of the converter operation, e.g., arc welding. The principle of operation is explained and analyzed, and experimental results are presented on a 3-kW 50-kHz laboratory converter model. © 2006 IEEE.


Bica A.M.,University of Oradea
Fuzzy Sets and Systems | Year: 2013

In this paper we present the algebraic and topological structure of one-sided fuzzy numbers and introduce the notion of side preserving fuzzy-number-valued function. We define the dual decomposition of a commutative monoid and prove that the sets of left-sided fuzzy numbers and right-sided fuzzy numbers realize a dual decomposition of the additive monoid of all fuzzy numbers. We prove the usefulness of right-sided fuzzy numbers in epidemiology presenting an application of these fuzzy numbers to a mathematical model for the spread of infectious diseases with a rate of contact that varies seasonally. © 2012 Elsevier B.V.

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