Winston-Salem, NC, United States
Winston-Salem, NC, United States

The University of North Carolina School of the Arts is a public coeducational arts conservatory in Winston-Salem, North Carolina that grants high school, undergraduate and graduate degrees. It is one of the seventeen constituent campuses of the University of North Carolina. Founded in 1963 as the North Carolina School of the Arts by then-Governor Terry Sanford, it was the first public arts conservatory in the United States. The school owns and operates the Stevens Center in Downtown Winston-Salem and is accredited by the Southern Association of Colleges and Schools. Wikipedia.

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LaTuga M.S.,Yeshiva University | Stuebe A.,University of North Carolina School of the Arts | Seed P.C.,Duke University
Seminars in Reproductive Medicine | Year: 2014

Breast milk contains a rich microbiota composed of viable skin and non-skin bacteria. The extent of the breast milk microbiota diversity has been revealed through new culture-independent studies using microbial DNA signatures. However, the extent to which the breast milk microbiota are transferred from mother to infant and the function of these breast milk microbiota for the infant are only partially understood. Here, we appraise hypotheses regarding the formation of breast milk microbiota, including retrograde infant-to-mother transfer and enteromammary trafficking, and we review current knowledge of mechanisms determining the extent of breast milk microbiota transfer from mother to infant. We highlight known functions of constituents in the breast milk microbiota - to enhance immunity, liberate nutrients, synergize with breast milk oligosaccharides to enhance intestinal barrier function, and strengthen a functional gut-brain axis. We also consider the pathophysiology of maternal mastitis with respect to a dysbiosis or abnormal shift in the breast milk microbiota. In conclusion, through a complex, highly evolved process in the early stages of discovery, mothers transfer the breast milk microbiota to their infants to impact infant growth and development.© 2014 by Thieme Medical Publishers.

News Article | December 14, 2016

2016 marked a banner year for digital marketing and communications firm mStoner, Inc. with 25 awards from nine national award-granting organizations. Notably, The University of North Carolina School of the Arts was universally praised for its visual storytelling and immersive design. Receiving an award from all nine organizations, was granted the following distinctions: 2016 Webby-finalist, CASE Circle of Excellence Awards Silver, W3 Awards Best in Show, UCDA Design Competition Gold, and more. “People call our site ‘stunning’ and ‘beautiful,’ said Claire Machamer, chief technology officer at UNCSA. “Visual impact was one of our goals for the site and it was clearly accomplished. Social media referrals have skyrocketed because people are sharing the site; they’re proud of it.” Most importantly, mStoner’s digital strategy and creative work drove meaningful results for clients: broader brand awareness, increased admission inquiries and applications, revamped and impactful content strategies, and elevated institutional pride. “In the first week alone, our college admissions reps had too many prospects coming in for staff to get back to them. It’s a good problem to have,” said Mark Donahue, managing web editor at Rush University. With 2,000 new inquiry form submissions a month, the new is generating leads at 10 times the rate of the old site. Finding ways to help clients tell their stories with clarity, confidence, and conviction is what drives mStoner’s work. “These projects are the result of those collaborations,” says mStoner’s co-founder and CEO, Voltaire Santos Miran. “We’re honored for the recognition from so many different organizations. Helping our clients to reach their goals and solve their communications challenges is our real goal … but it’s also great to win an award or 25.” mStoner’s 2016 award-winning sites include: University of North Carolina School of the Arts Loyola Marymount University Tulane University Saint Louis University Tufts University (homepage) Tufts University Graduate School of Arts and Sciences and The School of Engineering Rush University University of Rochester School of Nursing Northwestern University in Qatar Johns Hopkins University Homewood Student Affairs See a complete list of 2016 accolades at

Hoenig M.P.,Beth Israel Deaconess Medical Center | Hoenig M.P.,Harvard University | Shapiro E.,American Society of Nephrology | Hladik G.A.,University of North Carolina School of the Arts | Hladik G.A.,University of North Carolina at Chapel Hill
Clinical Journal of the American Society of Nephrology | Year: 2013

Nephrology ranks next to last in career choices among US medical school graduates. The American Society of Nephrology established a Workforce Committee to help address this issue. Surveys of US medical students indicate that experiences during kidney pathophysiology courses in the preclerkship yearsmay impact their decision to consider a career in nephrology. InOctober of 2011, preclinical kidney physiology and pathophysiology course directors at US medical schools were surveyed about teaching methods, curricular content, resources, and institutional support for teaching to identify what worked well and what impairs their teaching efforts. A Listserv of these educators, the American Society of Nephrology Renal Educators Listserv, was used to electronically administer the survey. Course leaders from 62 of 114 (54.4%) surveyed medical schools responded. Most of these educators are nephrologists, but physiologists and other clinicians also lead courses; 60% of course directors noted that lectures are videotaped, resulting in decreased attendance. A range of resources is used: 68% use audience response systems, 16% use the simulation center, and none of the educators indicated use of social media (such as Twitter or Facebook); 50%of respondents receive no remuneration, and 68%receive no full-time equivalent for their efforts. Audience response systems, virtual microscopy, and flash animations were identified as valuable teaching tools. Course directors, during subsequent dialogue on the American Society of Nephrology Renal Educators Listserv, have cited incorporation of case scenarios and integration of clinical exposure during preclinical years asmethods that inspired interest. Hopefully, adoption of such approaches will ultimately serve to stimulate interest in nephrology. © 2013 by the American Society of Nephrology.

Lazaro-Munoz G.,University of North Carolina School of the Arts
Journal of Law, Medicine and Ethics | Year: 2014

This paper examines how the application of legal fiduciary principles (e.g., physicians' duty of loyalty and care, duty to inform, and duty act within the scope of authority), can serve as a framework to promote management of clinical genomic "incidental" or secondary target findings that is patient-centered and consistent with recognized patient autonomy rights. The application of fiduciary principles to the clinical genomic testing context gives rise to at least four physician fiduciary duties in conflict with recent recommendations by the American College of Medical Genetics and Genomics (ACMG). These recommendations have generated much debate among lawyers, clinicians, and bioethicists hence I believe this publication will be of value and interest to your readership. © 2014 American Society of Law, Medicine & Ethics, Inc.

Meltzer E.O.,Allergy and Asthma Medical Group and Research Center | Kuna P.,Medical University of Lódz | Nolte H.,Sharp Corporation | Nayak A.S.,Wheeze and Itch Associates LLC | LaForce C.,University of North Carolina School of the Arts
European Respiratory Journal | Year: 2012

This study evaluated the effect of mometasone furoate (MF)/formoterol (F) versus its monocomponents, each administered via metered-dose inhaler, on asthma deteriorations and lung function. This 26-week, multicentre, double-blind, placebo-controlled study included subjects aged ≥ 12 yrs with not well-controlled asthma on low-dose inhaled corticosteroids. After a 2-3-week open-label runin (MF 100 μg b.i.d.), 746 subjects were randomised to receive placebo, F 10 μg, MF 100 μg or MF/F 100/10 μg b.i.d. Co-primary end-points were time to first asthma deterioration (MF/F versus F to assess effect of MF) and change in forced expiratory volume in 1 s (FEV1) area under the curve of serial spirometry measurements over the 12-h period following the morning dose (AUC0-12h) (baseline to week 12; MF/F versus MF to assess effect of F). The therapeutic effect of MF in the combination was demonstrated by a reduction in asthma deterioration incidence with MF/F versus F and a delayed time to first asthma deterioration (p<0.001). Asthma deterioration incidence was also reduced with MF/F versus MF (p50.006). The therapeutic effect of F in the combination was demonstrated by MF/F versus MF in FEV1 AUC0-12h change (4.00 versus 2.53 L·h, respectively; p50.001). MF/F treatment also resulted in a marked improvement in health-related quality of life. MF/F 100/10 μg b.i.d. treatment showed greater clinical efficacy than its individual components or placebo; both components contributed to the efficacy of MF/F. Copyright©ERS 2012.

De Bellis M.D.,Duke University | Hooper S.R.,University of North Carolina School of the Arts | Hooper S.R.,Duke University | Woolley D.P.,Duke University | Shenk C.E.,University of Cincinnati
Journal of Pediatric Psychology | Year: 2010

ObjectiveTo examine the relationships of demographic, maltreatment, neurostructural and neuropsychological measures with total posttraumatic stress disorder (PTSD) symptoms.MethodsParticipants included 216 children with maltreatment histories (N = 49), maltreatment and PTSD (N = 49), or no maltreatment (N = 118). Participants received diagnostic interviews, brain imaging, and neuropsychological evaluations.ResultsWe examined a hierarchical regression model comprised of independent variables including demographics, trauma and maltreatment-related variables, and hippocampal volumes and neuropsychological measures to model PTSD symptoms. Important independent contributors to this model were SES, and General Maltreatment and Sexual Abuse Factors. Although hippocampal volumes were not significant, Visual Memory was a significant contributor to this model.ConclusionsSimilar to adult PTSD, pediatric PTSD symptoms are associated with lower Visual Memory performance. It is an important correlate of PTSD beyond established predictors of PTSD symptoms. These results support models of developmental traumatology and suggest that treatments which enhance visual memory may decrease symptoms of PTSD. © The Author 2009.

Jonas D.E.,University of North Carolina School of the Arts
North Carolina medical journal | Year: 2013

Pharmacogenomics offers the hope of greater individualization of treatment. Therapies that exemplify the promise of pharmacogenomics include anticoagulation with warfarin and the use of antiplatelet medications (eg, clopidogrel) for secondary prevention after acute coronary syndrome. Good evidence of clinical utility must be obtained before pharmacogenomic testing is widely implemented.

Olbert C.M.,Fordham University | Gala G.J.,University of North Carolina School of the Arts | Tupler L.A.,Duke University
Journal of Abnormal Psychology | Year: 2014

Heterogeneity within psychiatric disorders is both theoretically and practically problematic: For many disorders, it is possible for 2 individuals to share very few or even no symptoms in common yet share the same diagnosis. Polythetic diagnostic criteria have long been recognized to contribute to this heterogeneity, yet no unified theoretical understanding of the coherence of symptom criteria sets currently exists. A general framework for analyzing the logical and mathematical structure, coherence, and diversity of Diagnostic and Statistical Manual diagnostic categories (DSM-5 and DSM-IV-TR) is proposed, drawing from combinatorial mathematics, set theory, and information theory. Theoretical application of this framework to 18 diagnostic categories indicates that in most categories, 2 individuals with the same diagnosis may share no symptoms in common, and that any 2 theoretically possible symptom combinations will share on average less than half their symptoms. Application of this framework to 2 large empirical datasets indicates that patients who meet symptom criteria for major depressive disorder and posttraumatic stress disorder tend to share approximately three-fifths of symptoms in common. For both disorders in each of the datasets, pairs of individuals who shared no common symptoms were observed. Any 2 individuals with either diagnosis were unlikely to exhibit identical symptomatology. The theoretical and empirical results stemming from this approach have substantive implications for etiological research into, and measurement of, psychiatric disorders. © 2014 American Psychological Association.

Farahi N.,University of North Carolina at Chapel Hill | Zolotor A.,University of North Carolina at Chapel Hill | Zolotor A.,University of North Carolina School of the Arts
American Family Physician | Year: 2013

Given that nearly one-half of pregnancies are unintended, preconception care should be considered an integral part of primary care for women of reproductive age. Common issues in preconception care include family planning, achieving a healthy body weight, screening and treatment for infectious diseases, updating appropriate immunizations, and reviewing medications for teratogenic effects. Women who want to become pregnant should take folic acid supplements to reduce the risk of neural tube defects. Control of chronic diseases is essential for optimizing pregnancy outcomes. Family physicians should work with patients to control conditions such as diabetes mellitus, hypertension, and seizure disorders while simultaneously offering family planning services to avoid unintended pregnancies. Bariatric surgery is increasingly common and may improve fertility in many women with previous insulin resistance. Family physicians should counsel women undergoing bariatric surgery to prevent pregnancy during rapid weight loss and provide assistance with contraception. In addition, patients have special nutritional requirements after bariatric surgery. © 2013 American Academy of Family Physicians.

Saver R.S.,University of North Carolina School of the Arts
Journal of Law, Medicine and Ethics | Year: 2012

Concern about financial conflicts crowds out sufficient consideration of other interests that may bias research conduct. Regulations, institutional policies, and guidance from professional bodies and medical journals all primarily focus on financial ties. But why? Economic gain is not the only powerful influence. This article argues that we under-prioritize non-financial interests in the regulation of medical research. It critiques the usual reasons given for regulating financial and non-financial interests differently - that the interests contrast in terms of tangibility, that financial interests are optional, and that financial interests can be efficiently carved out as a discrete area of focus. Moreover, disparate regulatory treatment seems inattentive to the very similar social and psychological forces that animate the bias effect of both financial and non-financial interests and fails to account for how financial and non-financial interests synergistically interact. Under-prioritization of non-financial interests threatens to erode public trust and creates negative spillover effects that weaken financial conflicts regulation. Optimal regulation requires a more integrated, balanced, and proportionate response to secondary interests in medical research. © 2012 American Society of Law, Medicine & Ethics, Inc.

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