Chapel Hill, NC, United States

University of North Carolina at Chapel Hill

www.unc.edu
Chapel Hill, NC, United States

The University of North Carolina at Chapel Hill is a coeducational public research university located in Chapel Hill, North Carolina, United States. North Carolina has been consistently listed among the highest and best ranked universities in the United States and is one of the original eight Public Ivy schools that provide an Ivy League experience for a public schooling price. After being chartered in 1789, the university first began enrolling students in 1795, which allows it to be one of three schools to claim the title of the oldest public university in the United States.The first public institution of higher education in North Carolina, the school opened its doors to students on February 12, 1795. The university offers degrees in over 70 courses of study through fourteen colleges and the College of Arts and science. All undergraduates receive a liberal arts education and have the option to pursue a major within the professional schools of the university or within the College of Arts and science from the time they obtain junior status. Under the leadership of President Kemp Plummer Battle, in 1877 North Carolina became coeducational and began the process of desegregation in 1951 when African-American graduate students were admitted under Chancellor Robert Burton House. In 1952, North Carolina opened its own hospital, UNC Health Care, for research and treatment, and has since specialized in cancer care. The school's students, alumni, and sports teams are known as "Tar Heels".The campus of North Carolina is located in Chapel Hill, North Carolina, a university town. The campus covers a rather small 729 acres over Chapel Hill's downtown area, encompassing places like the Morehead Planetarium and the many stores and shops located on Franklin Street. Students can participate in over 550 officially recognized student organizations. The student-run newspaper The Daily Tar Heel has won national awards for collegiate media, while the student radio station WXYC provided the world's first internet radio broadcast. North Carolina is one of the charter members of the Atlantic Coast Conference, which was founded on June 14, 1953. Competing athletically as the Tar Heels, North Carolina has achieved great success in sports, most notably in men's basketball, women's soccer, and women's field hockey. Wikipedia.


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Patent
Entegrion and University of North Carolina at Chapel Hill | Date: 2017-02-22

The present invention is directed to a hemostatic textile, comprising: a material comprising a combination of glass fibers and one or more secondary fibers selected from the group consisting of silk fibers; ceramic fibers; raw or regenerated bamboo fibers; cotton fibers; rayon fibers; linen fibers; ramie fibers; jute fibers; sisal fibers; flax fibers; soybean fibers; corn fibers; hemp fibers; lyocel fibers; wool; lactide and/or glycolide polymers; lactide/glycolide copolymers; silicate fibers; polyamide fibers; feldspar fibers; zeolite fibers, zeolite-containing fibers, acetate fibers; and combinations thereof; the hemostatic textile capable of activating hemostatic systems in the body when applied to a wound. Additional cofactors such as thrombin and hemostatic agents such as RL platelets, RL blood cells; fibrin, fibrinogen, and combinations thereof may also be incorporated into the textile. The invention is also directed to methods of producing the textile, and methods of using the textile to stop bleeding. (Drawing Figure 1)


Patent
University of North Carolina at Chapel Hill | Date: 2017-02-24

Mass spectrometry systems or assemblies therefore include an ionizer that includes at least one planar conductor, a mass analyzer with a planar electrode assembly, and a detector comprising at least one planar conductor. The ionizer, the mass analyzer and the detector are attached together in a compact stack assembly. The stack assembly has a perimeter that bounds an area that is between about 0.01 mm^(2 )to about 25 cm^(2 )and the stack assembly has a thickness that is between about 0.1 mm to about 25 mm.


Patent
University of North Carolina at Chapel Hill | Date: 2017-02-24

The present invention relates to antibodies targeted to BDCA2 that deplete plasmacytoid dendritic cells (pDC) and methods of using the antibodies to treat disorders associated with pDC.


Patent
University of North Carolina at Chapel Hill | Date: 2017-03-01

Devices and methods generate an ordered restriction map of genomic DNA extracted from whole cells. The devices have a fluidic microchannel that merges into a reaction nanochannel that merges into a detection nanochannel at an interface where the nanochannel diameter decreases in size by between 50% to 99%. Intact molecules of DNA are transported to the reaction nanochannel and then fragmented in the reaction nanochannel using restriction endonuclease enzymes. The reaction nanochannel is sized and configured so that the fragments stay in an original order until they are injected into the detection nanochannel. Signal at one or more locations along the detection nanochannel is detected to map fragments in the order they occur along a long DNA molecule.


Patent
GeneCentric Diagnostics and University of North Carolina at Chapel Hill | Date: 2017-04-05

Methods and compositions are provided for the molecular subtyping of lung cancer samples. Specifically, a method of assessing whether a patients lung cancer subtype is adenocarcinoma, squamous cell carcinoma, or a neuroendocrine (encompassing both small cell carcinoma and carcinoid) is provided herein. A method for assessing whether a patients lung cancer subtype is adenocarcinoma, squamous cell carcinoma, small cell carcinoma or carcinoid lung cancer is also provided. The methods provided herein entail probing the levels of the classifier biomarkers of Table 1-Table 6 or a subset thereof at the nucleic acid level, in a lung cancer sample obtained from the patient. Based in part on the levels of the classifier biomarkers, the lung cancer sample is classified as a particular lung cancer subtype.


Patent
University of North Carolina at Chapel Hill and New York University | Date: 2017-01-23

Methods, systems, and computer readable media for preventing code reuse attacks are disclosed. According to one method, the method includes executing, on a processor, code in a memory page related to an application, wherein the memory page is protected. The method also includes detecting a read request associated with the code. The method further includes after detecting the read request, modifying, without using a hypervisor, at least one memory permission associated with the memory page such that the code is no longer executable after the code is read.


Patent
University of North Carolina at Chapel Hill and Spyryx Biosciences | Date: 2017-04-21

The present invention relates to the ability of specialized non-naturally occurring peptides to bind to sodium channels and inhibit activation of the sodium channels. The invention further relates to methods for regulating of sodium absorption and fluid volume and treating disorders responsive to modulating sodium absorption by modulating the binding of specialized non-naturally occurring peptides to sodium channels.


Patent
Duke University, MacroGenics and University of North Carolina at Chapel Hill | Date: 2017-08-09

The invention is directed to bispecific molecules comprising an HIV-1 envelope targeting arm and an arm targeting an effector cell, compositions comprising these bispecific molecules and methods of use. In certain aspects, the bispecific molecules of the present invention can bind to two different targets or epitopes on two different cells wherein the first epitope is expressed on a different cell type than the second epitope, such that the bispecific molecules can bring the two cells together. In certain aspects, the bispecific molecules of the present invention can bind to two different cells, wherein the bispecific molecules comprises an arm with the binding specificity of A32, 7B2, CH27, CH28 or CH44.


Patent
University of North Carolina at Chapel Hill | Date: 2017-02-01

Optical geometry calibration devices, systems, and related methods for x-ray imaging are disclosed. An optical-based geometry calibration device is configured to interface with a two-dimensional (2D) imaging device to perform three-dimensional (3D) imaging. The optical-based geometry calibration device includes one or more optical cameras fixed to either an x-ray source or an x-ray detector, one or more markers fixed to the x-ray detector or the x-ray source, with each of the one or more optical cameras being configured to capture at least one photographic image of one or more corresponding optical markers when each x-ray image of the object is captured, and an image processing system configured to compute positions of the x-ray source relative to the x-ray detector for each 2D projection image based on the at least one photographic image of the one or more markers


Patent
Fontem Holdings 1 B.V., Wensley, University of North Carolina at Chapel Hill and Jülich Research Center | Date: 2017-07-19

A device for generating a condensation aerosol includes (a) vaporization chamber having an upstream first inlet and a downstream outlet; (b) a heater element in the vaporization chamber between the upstream first inlet and the downstream outlet; (c) an airflow path in fluid communication with the vaporization chamber, wherein the airflow path comprises a second inlet configured to permit a substantially laminar flow of air into the airflow path, wherein the second inlet is downstream of the heater element; and (d) the device having components or apparatus on or in the device for changing air flow in the vaporization chamber. Changing the air flow in the vaporization chamber may be used to change the particle size of a condensation aerosol produced in the vaporization chamber, and/or to change the amount of visible vapor emitted from the device.

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