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Fredericton, Canada

The University of New Brunswick is a public university with campuses located in Fredericton and Saint John, New Brunswick. It is the oldest English language university in Canada. It is one of four schools that claim the title of oldest public university in North America . UNB was founded by a group of seven Loyalists who left the United States after the American Revolution.UNB has two main campuses: the original campus, founded in 1785 in Fredericton, and a smaller campus which opened in Saint John in 1964. In addition, there are two small satellite health science campuses located in Moncton and Bathurst, New Brunswick, and two offices in the Caribbean and in Beijing. UNB offers over 75 degrees in fourteen faculties at the undergraduate and graduate levels with a total student enrollment of approximately 11,400 between the two principal campuses. In the fall of 2010, UNB partnered with Dalhousie University and the government of New Brunswick to open the first English-language medical school in the province at the Saint John campus. Wikipedia.

McCloskey R.M.,University of New Brunswick
Journal of the American Geriatrics Society | Year: 2011

Nursing home (NH) residents who have exacerbations of chronic health conditions or new illnesses must generally go the emergency department (ED) for health care, later returning to the nursing home when it is felt that they are no longer require acute care. Transfers between settings of care are referred to as transitions, and research has shown that residents are at risk of experiencing negative health outcomes during these periods. This article reports on a qualitative study of resident transfers between one NH and one ED in Canada. Data were collected using interviews, participant observation, and examination of institutional policies and standard practices. Three themes emerged from the data: (1) work of executing transfers; (2) creating and exchanging resident information; and (3) feelings of guilt but not being responsible about how residents' transfers occurred. Although completion of organization-specific forms consumed a considerable amount of practitioners' time, they contributed little to resident transfers or to the sharing of information. There is a need for integrated models of care that transcend settings and promote an understanding of the roles and responsibilities of practitioners working along the entire continuum of care. © 2011, The American Geriatrics Society. Source

Thomas M.,University of New Brunswick
Cement and Concrete Research | Year: 2011

This paper reviews studies on the effect of supplementary cementing materials (SCM) on alkali-silica reaction (ASR). SCMs control expansion due to ASR by binding alkalis and limiting their availability for reaction with alkali-silica reactive aggregate. The efficacy of the SCM is dependent on the composition of the SCM. Increased amounts of SCM are required to control ASR as its calcium and alkali content increase, as its silica content decreases, as the alkali contributed by the Portland cement increases and as the reactivity of the aggregate increases. There is evidence that the alumina content of the SCM also affects its alkali-binding capacity, however, the precise role and contribution of the alumina is not clear. © 2010 Elsevier Ltd. All rights reserved. Source

Spray J.G.,University of New Brunswick
Annual Review of Earth and Planetary Sciences | Year: 2010

Frictional melting is the result of the conversion of mechanical deformation to heat under adiabatic conditions of slip. Within planetary materials, which are mainly natural ceramics, frictional melting occurs at high strain rates (typically >10-2 s-1) and at slip velocities greater than 0.1 m s-1. The pathway to friction melting is controlled by the mechanical properties of a rock's constituent minerals, especially fracture toughness. Minerals with the lowest fracture toughnesses and breakdown temperatures are preferentially comminuted and fused to form the melt. The product is a polyphase suspension comprising mineral and rock fragments enclosed in a liquid matrix. This cools to form the rock type known as pseudotachylyte, and at even higher strain rates, it forms shock veins in meteorites and in impact craters, which may contain high-pressure mineral polymorphs. The generation of melt on sliding surfaces can lubricate earthquake faults, facilitate the post-shock modification of impact craters, and make landslides more hazardous. Copyright © 2010 by Annual Reviews. All rights reserved. Source

Feng Z.,University of New Brunswick
Cold Spring Harbor perspectives in biology | Year: 2010

In response to various stress signals, which introduce infidelity into the processes of cell growth and division, p53 initiates cell-cycle arrest, apoptosis, or senescence to maintain fidelity throughout the cell cycle. Although these functions are traditionally thought of as the major functions of the p53 protein for tumor suppression, recent studies have revealed some additional novel functions of the p53 pathway. These include the down-regulation of two central cell-growth pathways, the IGF/AKT-1 and mTOR pathways, and the up-regulation of the activities of the endosomal compartment. The IGF-1/AKT and mTOR pathways are two evolutionarily conserved pathways that play critical roles in regulation of cell proliferation, survival, and energy metabolism. In response to stress, p53 transcribes a group of critical negative regulators in these two pathways, including IGF-BP3, PTEN, TSC2, AMPK beta1, and Sestrin1/2, which leads to the reduction in the activities of these two pathways. Furthermore, p53 transcribes several critical genes regulating the endosomal compartment, including TSAP6, Chmp4C, Caveolin-1, and DRAM, and increases exosome secretion, the rate of endosomal removal of growth factor receptors (e.g., EGFR) from cell surface, and enhances autophagy. These activities all function to slow down cell growth and division, conserve and recycle cellular resources, communicate with adjacent cells and dendritic cells of the immune system, and inform other tissues of the stress signals. This coordinated regulation of IGF-1/AKT/mTOR pathways and the endosomal compartment by the p53 pathway integrates the molecular, cellular, and systemic levels of activities and prevents the accumulations of errors in response to stress and restores cellular homeostasis after stress. Source

For women, any one type of abuse rarely occurs in isolation of other types, and a single abusive experience is often the exception rather than the norm. The importance of this concept of the cumulative nature of abuse and its negative impact on health has been well recognized within the empirical literature, however there has been little consensus on what to call this phenomenon or how to study it. For the most part researchers have operated on the premise that it is the sheer number of different types of cumulating abuse experiences that is primarily responsible for worse health outcomes among women. And although this simplistic 'more is worse' approach to conceptualizing and operationalizing cumulative abuse has proven to be a powerful predictor of poorer health, it contradicts growing empirical evidence that suggests not all victimizations are created equal and that some victimizations may have a more deleterious effect on health than others. Embedded in abuse histories are individual and abuse characteristics as well as other life adversities that need to be considered in order to fully understand the spectrum and magnitude of cumulative abuse and its impact on women's health. Furthermore, given the long-term and persistent effects of abuse on health it becomes imperative to not only evaluate recent abusive experiences, but rather all abuse experiences occurring across the lifespan. This review highlights and evaluates the conceptual, operational, and methodological challenges posed by our current methods of studying and understanding the phenomenon of cumulative abuse and suggests that this phenomenon and its relationship to health is much more complex than research is currently portraying. This paper calls for the urgent need for interdisciplinary collaboration in order to more effectively and innovatively study the phenomenon of cumulative abuse. © The Author(s) 2011. Source

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