The University of Neuchâtel is a French-speaking university in Neuchâtel, Switzerland. The university has five faculties and more than a dozen institutes, including arts and human science, natural science, law, economics and theology. The Faculty of Arts and Human science is the largest school of those that comprise the University of Neuchâtel with 1,500 students.The university has an annual budget of CHF 120 million and an annual research fund of CHF 40 million. Approximately 4,000 students, including 500 PhD students attend the university, and more than 600 diplomas, licences, doctorates and certificates are awarded each year. The university has more than 1100 employees. Wikipedia.
Piguet E.,University of Neuchatel
Annals of the Association of American Geographers | Year: 2013
Beginning with Friedrich Ratzel, the founders of migration studies all mentioned the natural environment as an important determinant of human mobility. As migration theories grew in coherence and complexity over the course of the twentieth century, however, environmental considerations generally disappeared from explanations of displacement. They would reappear in a largely unconnected discourse stressing the threat of future waves of "environmental migrants" in the end-of-the-century context of climate change anxiety. This alarmist stance was heavily criticized by several migration scholars during the same period of time as a corpus of empirical studies emerged that reconsidered the possible impact of the environment on migration. The purpose of this article is to analyze the intellectual history of this swing of the pendulum. The first part examines the rationale for the temporary disappearance of the environment from migration studies, as this major shift has not yet been fully or systematically studied. The second part considers the renewal of interest in environmental migration. Finally, the last part argues that although a solid body of new research documents the contemporary migration-environment nexus, additional work is needed to reembed the environment more firmly within migration theories, taking into account the increased focus on the nature-society nexus, which has recently expanded in geography. © 2013 Copyright Taylor and Francis Group, LLC.
Furrer J.,University of Neuchatel
Chemical Communications | Year: 2010
A robust, versatile and easy to optimize HMBC experiment for complex organic structure elucidation which has been experimentally tested on cholesteryl acetate, cyclosporine and isopropylidene glycerol is described. The proposed experiment, IMPACT-HMBC (improved and accelerated constant-time heteronuclear multiple-bond correlation), combines sensitivity, easy experimental setup and can be recorded with short recovery times. © 2010 The Royal Society of Chemistry.
Suss-Fink G.,University of Neuchatel
Journal of Organometallic Chemistry | Year: 2014
Shortly after the discovery of benzene ruthenium dichloride and some controversy about its polymeric or dimeric nature in the 1960s, the hydrolysis of this material in water to give a mixture of benzene ruthenium aqua complexes was discovered. However, it took a long time until this reaction and the hydrolysis of other arene analogs were used as an entry to the synthesis of water-soluble arene ruthenium complexes. These complexes are able to activate molecular hydrogen in aqueous solution and allow the design of arene ruthenium bioconjugates. They can serve as catalysts or catalyst precursors for hydrogenation and transfer hydrogenation reactions in water and they are at present one of the most promising classes of metal complexes to replace cisplatin in future cancer therapy, due to their inherent cytotoxicity and their good cellular uptake, conditioned by well balanced lipophilic and hydrophilic properties. © 2013 Elsevier B.V. All rights reserved.
Therrien B.,University of Neuchatel
CrystEngComm | Year: 2015
Arene ruthenium complexes have been known for 50 years and the number of publications involving arene ruthenium complexes has been in constant progression ever since their discovery. Following the synthesis and characterisation of the first arene ruthenium complexes, they have been initially tested as catalysts. Then later on, with the emergence of bio-inorganic chemistry, the biological activity of arene ruthenium complexes was explored. Lately, arene ruthenium complexes have become popular building blocks for the preparation of metalla-assemblies. In this highlight article, we present our contributions in the field of water soluble metalla-assemblies with an emphasis on their biological potentials, revealing that arene ruthenium complexes have found a new playground. This journal is © The Royal Society of Chemistry.
Suss-Fink G.,University of Neuchatel
Dalton Transactions | Year: 2010
Neutral or cationic arene ruthenium complexes providing both hydrophilic as well as hydrophobic properties due to the robustness of the ruthenium-arene unit hold a high potential for the development of metal-based anticancer drugs. Mononuclear arene ruthenium complexes containing P- or N-donor ligands or N,N-, N,O- or O,O-chelating ligands, dinuclear arene ruthenium systems with adjustable organic linkers, trinuclear arene ruthenium clusters containing an oxo cap, tetranuclear arene ruthenium porphyrin derivatives that are photoactive, as well as hexanuclear ruthenium cages that are either empty or filled with other molecules have been shown to be active against a variety of cancer cells. © The Royal Society of Chemistry 2010.