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Nantes, France

The University of Nantes is a French university, located in the city of Nantes. In addition to the several campuses scattered in the city of Nantes, there are two satellite campuses located respectively in Saint-Nazaire and La Roche-sur-Yon. Currently, the University is attended by approximately 34,500 students. More than 10% of them are international students coming from 110 countries.The University of Nantes was ranked between 600-650th in the QS World University Rankings of 2013. On a national scale and regarding the professional insertion after graduation, the University of Nantes oscillates between the ranks 3rd and 40th out of 69 universities depending on the field of studies. On overall, the university is ranked 45th out of 76 universities in France. Among its noticeable alumni are the former French Prime Minister Jean-Marc Ayrault as well as one of the French Ministers of Agriculture. Wikipedia.

Denes F.,University of Nantes | Pichowicz M.,University of Bern | Povie G.,University of Bern | Renaud P.,University of Bern
Chemical Reviews | Year: 2014

The review covers the uses of thiyl radicals in organic synthesis and provides mechanistic information to understand these processes and to design new synthetic applications. It describes the main elementary reactions involving thiyl radicals and discusses the factors directing the rates and selectivity of these processes. The reaction of sulfur-containing molecules with another radical is a preeminent source of thiyl radicals. Thiols can rapidly transfer a hydrogen atom to most types of radical X having a corresponding higher X-H BDE. All the commonly used initiators such as azo-compounds or peroxides that generate alkyl or alkoxyl radicals are efficient to initiate thiol-mediated radical transformations.

Gouin S.G.,University of Nantes
Chemistry - A European Journal | Year: 2014

During the last decades, tremendous chemical efforts have been dedicated to design monovalent inhibitors of carbohydrate-processing enzymes, with comparatively few rewards in terms of marketed drugs. Recently, an alternative to the traditional "lock and key" approach has emerged. Multivalency, a widely used strategy for lectin inhibition, has been successfully applied to specific glycosidases and glycosyltransferases. © 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Werner K.,University of Nantes
Physical Review Letters | Year: 2012

We introduced recently a new theoretical scheme which accounts for hydrodynamically expanding bulk matter, jets, and the interaction between the two. Important for the particle production at intermediate values of transverse momentum (p t) are jet hadrons produced inside the fluid. They pick up quarks and antiquarks (or diquarks) from the thermal matter rather than creating them via the Schwinger mechanism-the usual mechanism of hadron production from string fragmentation. These hadrons carry plasma properties (flavor, flow) but also the large momentum of the transversely moving string segment connecting quark and antiquark (or diquark). They therefore show up at quite large values of p t, not polluted by soft particle production. We will show that this mechanism leads to a pronounced peak in the Lambda-to-kaon ratio at intermediate p t. The effect increases substantially with centrality, which reflects the increasing transverse size with centrality. © 2012 American Physical Society.

This account summarizes ten years of projects in the Felpin group involving Pd/C as a catalyst for cross-coupling reactions. From early studies to recent developments, the story tells of the successes and the failures, and it shows the progress gained in understanding of factors governing the catalytic activity and efficiency of Pd/C catalysts. This account could serve as a textbook for synthetic chemists interested in practical methodologies involving C-C bond formation. 1 Introduction 2 Pd/C: Basic Knowledge 3 Early Studies 4 Homemade Pd/C Catalysts 5 Future Prospects 6 Summary and Outlook © Georg Thieme Verlag Stuttgart New York.

Hug F.,University of Nantes
Journal of Electromyography and Kinesiology | Year: 2011

Despite the many reviews and research papers on the limitations of surface electromyography (EMG), there are relatively few that address this issue by considering dynamic contractions and specifically from the point of view of muscle coordination. Nevertheless, whether muscle coordination can be precisely studied using surface EMG signals is still a matter of discussion in the scientific community. In other words, it is uncertain whether neural control strategies of movement can be inferred from EMG. This review article discusses the appropriateness of using EMG recordings for studying muscle coordination. First, the main uses of surface EMG for studying muscle coordination are depicted. Then, the main intrinsic drawbacks of the EMG technique (i.e., amplitude cancellation, crosstalk and spatial variability of muscle activity) and of EMG processing (i.e., smoothing of the linear envelope, normalization of the time scale and the amplitude and timing of muscle activation) are described and discussed. Finally, three other factors (i.e., variability, electromechanical delay and neuromuscular fatigue), which can affect the interpretation of EMG and have received little attention in the literature, are presented and discussed. All of this information is crucial to the proper interpretation of muscle coordination from EMG signals. © 2010 Elsevier Ltd.

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