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Mysore, India

The University of Mysore is a public state university located in Mysore, Karnataka, India. The university was founded during the reign of Krishnaraja Wodeyar IV, the Maharaja of Mysore. It opened on 27 July 1916, with the first chancellor being the Maharaja of Mysore and the first Vice Chancellor being H. V. Nanjundaiah. The university became the first outside the domain of the Britain administration in India, the sixth university in India as a whole, and the first ever university in Karnataka. It is a state university of the affiliating type, and became autonomous on 3 March 1956, when it gained recognition from the University Grants Commission.The university encompasses 122 affiliated colleges and five constituent colleges . In addition, the university has 37 postgraduate departments, eight specialised research and training centres and two postgraduate centres that together offer about 55 regular academic programmes to 3,500 students. It also runs a number of employment-oriented diploma courses and certificate programmes.The Mysore University Library comprises over 800,000 books, 2,400 journal titles and 100,000 volumes of journals. The main campus features an amphitheater, an auditorium, a swimming pool, and hostel accommodation for men and women. As of July 2013, the University of Mysore was accredited "Grade A" by National Assessment and Accreditation Council , while its academic staff was ranked amongst the top 5 across India. Wikipedia.

Harinarayana N.S.,University of Mysore | Raju N.V.,Government First Grade College
Electronic Library | Year: 2010

Purpose - The purpose of this paper is to explore recent trends in the application of Web 2.0 and Library 2.0 features as exemplified through university library web sites around the world. Design/methodology/approach - The top 100 universities from the ranked list of 200 provided on the Times Higher Education web site were considered for collection of data and from this list a selection was made of 57 of these universities. This selection was based on whether the site was in English and whether it had at least one Web 2.0 feature. For each of these universities their web sites were visited and data on their Web 2.0 features (such as Blogs, RSS, Instant Messaging, Wikis and the like) were collected and analyzed. Findings - Results reveal that 37 university libraries use RSS feeds for dissemination of library news, events and announcements and 15 university libraries provide blog space for users. Whereas wiki is the least applied Web 2.0 technology, with only one university using it, Instant Messaging is another most widely applied feature with 37 libraries already providing reference service through it. Podcast (used in three libraries) and Vidcast (used in six libraries) are yet to become popular facilities to be offered in university library web sites. Research limitations/implications - The study is based on the university ranking for 2007, as the World Top 200 Universities 2008 was not published until October 2008 when this article was being finalized. However, this does not affect the outcome of the Web 2.0 features being utilized by the universities. Originality/value - Most of the earlier studies on the subject deal with Web 2.0 tools and how they could be used in the library context. The present paper, however, provides concrete evidence of the application of Web 2.0 in university libraries. As such it should prove of interest to all types of libraries, even though its context is university libraries. © Emerald Group Publishing Limited 0264-0473. Source

Prakash J.,University of Mysore
Journal of the Science of Food and Agriculture | Year: 2014

Safe and adequate food is a human right, safety being a prime quality attribute without which food is unfit for consumption. Food safety regulations are framed to exercise control over all types of food produced, processed and sold so that the customer is assured that the food consumed will not cause any harm. From the Indian perspective, global harmonisation of food regulations is needed to improve food and nutrition security, the food trade and delivery of safe ready-to-eat (RTE) foods at all places and at all times. The Millennium Development Goals (MDGs) put forward to transform developing societies incorporate many food safety issues. The success of the MDGs, including that of poverty reduction, will in part depend on an effective reduction of food-borne diseases, particularly among the vulnerable group, which includes women and children. Food- and water-borne illnesses can be a serious health hazard, being responsible for high incidences of morbidity and mortality across all age groups of people. Global harmonisation of food regulations would assist in facilitating food trade within and outside India through better compliance, ensuring the safety of RTE catered foods, as well as addressing issues related to the environment. At the same time, regulations need to be optimum, as overregulation may have undue negative effects on the food trade. © 2013 Society of Chemical Industry. Source

Bai A.J.,University of Mysore | Rai V.R.,University of Mysore
Comprehensive Reviews in Food Science and Food Safety | Year: 2011

Food spoilage and biofilm formation by food-related bacteria are significant problems in the food industry. Even with the application of modern-day food preservative techniques, excessive amounts of food are lost due to microbial spoilage. A number of studies have indicated that quorum sensing plays a major role in food spoilage, biofilm formation, and food-related pathogenesis. Understanding bacterial quorum-sensing signaling systems can help in controlling the growth of undesirable food-related bacteria. This review focusses on the various signaling molecules produced by Gram-negative and Gram-positive bacteria and the mechanism of their quorum-sensing systems, types of signaling molecules that have been detected in different food systems using biosensors, the role of signaling molecules in biofilm formation, and significance of biofilms in the food industry. As quorum-sensing signaling molecules are implicated in food spoilage, based on these molecules potential, quorum-sensing inhibitors/antagonists can be developed to be used as novel food preservatives for maintaining food integrity and enhancing food safety. Practical Application: Bacteria use signaling molecules for inter- and intracellular communication. This phenomenon of bacterial cell-to-cell communication is known as quorum sensing. Quorum-sensing signals are implicated in bacterial pathogenicity and food spoilage. Therefore, blocking the quorum-sensing signaling molecules in food-related bacteria may possibly prevent quorum-sensing-regulated phenotypes responsible for food spoilage. Quorum-sensing inhibitors/antagonists could be used as food preservatives to enhance the shelf life and also increase food safety. © 2011 Institute of Food Technologists ®. Source

Zarei M.,University of Mysore | Shivanandappa T.,University of Mysore
Food and Chemical Toxicology | Year: 2013

Hepatoprotective potential of the aqueous extract of the roots of Decalepis hamiltonii (DHA) against cyclophosphamide (CP)-induced oxidative stress has been investigated in mice. Administration of CP (25. mg/kg b.w., i.p) for 10. days induced hepatic damage as indicated by the serum marker enzymes aspartate and alanine transaminases (AST, ALT), alkaline phosphatase (ALP) and lactate dehydrogenase (LDH). Parallel to these changes CP induced oxidative stress in the liver as evident from the increased lipid peroxidation (LPO), reactive oxygen species (ROS), depletion of glutathione (GSH), and reduced activities of the antioxidant enzymes such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GR), and glutathione-S-transferase (GST). Treatment with DHA (50 and 100. mg/kg b.w., po) mitigated the CP-induced oxidative stress. Moreover, expression of genes for the antioxidant enzymes, were down-regulated by CP treatment which was reversed by DHA. Our study shows the DHA protected the liver from toxicity induced by CP and therefore, it could be serve as a safe medicinal supplement during cyclophosphamide chemotherapy. © 2013 Elsevier Ltd. Source

Belugali Nataraj N.,University of Mysore | Salimath B.P.,University of Mysore
Cellular Signalling | Year: 2013

We have identified and characterized a novel proangiogenic glycoprotein (NAP) with molecular weight of 67. kDa from synovial fluid of rheumatoid arthritis patients. Proteomic analysis of the protein revealed 29% sequence coverage with maximum identity for human retinoblastoma binding protein 2. N-terminal amino acid sequence showed no identity to recently discovered protein sequences. NAP was also identified in both normal and tumor cell lines by Western blotting. NAP is a permeability factor as verified by miles permeability assay. The proangiogenic potential of NAP was identified using shell less CAM, rat cornea and tumor on CAM assays. NAP induces expression of VEGF and Flt-1 gene as verified by promoter reporter gene analysis. Further NAP induces proliferation of endothelial cells and formation of tube like structures. NAP is also involved in migration and invasion of tumor cells. Clinical data revealed the presence of NAP in breast cancer biopsies. We have developed monoclonal antibody (mAb), and specific ELISA, which confirmed the presence of NAP in the cytosol of tumor cells. The mAb effect was evaluated with established angiogenic assays. Further, we investigated the detailed mechanism by which NAP induces angiogenesis. NAP is phosphorylated by VEGF induced activation of MAPK and JNK pathways through VEGFR2 phosphorylation. NAP involves JNK pathway predominantly with further activation of NFκB in downstream processing of VEGF activation. Together these findings establish that NAP displays angiogenic properties and promotes efficient neovascularization both in vitro and in vivo models. These observations suggest that anti-NAP-mAb can be targeted for antiangiogenic therapy of cancer. © 2012 Elsevier Inc. Source

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