The University of Missouri–Kansas City is a public research university located in Kansas City, Missouri, USA. It is a part of the University of Missouri System. Its main campus is in Kansas City's Rockhill neighborhood east of the Country Club Plaza. The university's enrollment is more than 15,700 in 2014. Wikipedia.
News Article | May 25, 2017
Currently a practitioner at Houston Methodist, Dr. Woods was formerly in solo private practice for 16 years. Prior to that she served as full-time faculty at Baylor College of Medicine and Director of Therapeutic Endoscopy at Ben Taub Hospital, both in the Houston area. During her 10 years as faculty, she trained many fellows in the art of endoscopy. She received the ASGE Endoscopic Research Award in 1991, and the ASGE Distinguished Service Award in 2015. She was selected to serve on the U.S. Food and Drug Administration Gastrointestinal and Urologic Devices Panel in 1993. Since then, she has served continuously in various capacities for the panel. Throughout her multiple practices as academician, private practitioner and employed physician, Dr. Woods has maintained a passion for national service, with a focus on bringing the voice of the practicing clinician to the Society. As ASGE President, she will host the 2017 EndoVators Summit on the topic of "Simulators and the Future of Endoscopic Training," to explore current training models and methods of assessing endoscopic competence, identify the inherent deficiencies in the current model and define skills that would benefit from simulation training for new trainees and practitioners wishing to learn a new skill. Additionally, she will focus on advocacy in areas of practice management and reimbursement that will benefit both patients and providers. Dr. Woods shares with her fellow GI endoscopists a love of the technology that allows them not only to identify disease but also to use the scope as a tool for treatment and healing. Above all, she is passionate about developing relationships with patients and teaching them about disease management. She received her medical degree from the University of Missouri-Kansas City in 1983. Her internship and residency were in Internal Medicine at Baylor College of Medicine, Houston, Texas. She was Chief Medical Resident at the Houston VA Medical Center and then went on to a Gastroenterology fellowship at University of Texas Southwestern in Dallas, Texas. She returned to Baylor College of Medicine in Houston for an Advanced Endoscopy Fellowship and then joined the Baylor faculty. Her primary clinical areas of interest are general gastroenterology with a focus on EMR (endoscopic mucosal resection) of esophageal and colonic lesions, advanced polypectomy and ablation of Barrett's esophagus. Dr. Woods has authored or co-authored numerous publications and has been an invited speaker at many local and national conferences. She has been consistently named as a Best Doctor in various national and local publications. About the American Society for Gastrointestinal Endoscopy Since its founding in 1941, the American Society for Gastrointestinal Endoscopy (ASGE) has been dedicated to advancing patient care and digestive health by promoting excellence and innovation in gastrointestinal endoscopy. ASGE, with more than 15,000 members worldwide, promotes the highest standards for endoscopic training and practice, fosters endoscopic research, recognizes distinguished contributions to endoscopy, and is the foremost resource for endoscopic education. Visit www.asge.org and www.screen4coloncancer.org for more information and to find a qualified doctor in your area. About Endoscopy Endoscopy is performed by specially-trained physicians called endoscopists using the most current technology to diagnose and treat diseases of the gastrointestinal tract. Using flexible, thin tubes called endoscopes, endoscopists can access the human digestive tract without incisions via natural orifices. Endoscopes are designed with high-intensity lighting and fitted with precision devices that allow viewing and treatment of the gastrointestinal system. To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/leading-gastrointestinal-society-names-karen-l-woods-md-to-president-300464130.html
News Article | May 24, 2017
In “Christ's 40 Commandments” (published by WestBow Press), author Renee Valverde Wagenblatt identifies 40 commandments given by Christ. Each is followed by the associated verses in the Gospels. The author is embarking on a marketing campaign to expand the book’s reach. “In this busy world, this text enables the reader to gain a full body of knowledge about a command in just a few pages,” Wagenblatt explains. “To my knowledge there is not another book like this one. The novelty of the book is the format which is similar to a PowerPoint presentation with a command followed by verses as bullets.” With over 950 verses, it is more inclusive than a word search because it includes associated key words and Jesus’ exemplary actions. The New International Version is quoted but the book is designed to be compatible and beneficial with other translations. God’s 10 commandments, Christ’s parables and miracles are included. Wagenblatt adds, “This book is useful for novice, church member of scripture scholar. Whether you are curious about a command, preparing a sermon, or advising a church member, this text is a valuable tool.” “Christ's 40 Commandments” By Renee Valverde Wagenblatt Hardcover | 5.5 x 8.5 in | 286 pages | ISBN 9781490881539 Softcover | 5.5 x 8.5 in | 286 pages | ISBN 9781490881515 E-Book | 286 pages | ISBN 9781490881522 Available at Amazon and Barnes & Noble About the Author Renee Valverde Wagenblatt is a native of Kansas City, Missouri. When she was a young student, she helped classmates prepare for tests. She has taught various ages from preschool to seniors, including teaching elementary a couple of years. She has a master’s in adult education from the University of Missouri-Kansas City. Within the program she designed at UMKC, titled Training for Entrance and Standardized Tests, she taught college, graduate and professional school candidates for 21 years. She is presently employed at the University of Oklahoma-Tulsa. WestBow Press is a strategic supported self-publishing alliance between HarperCollins Christian Publishing and Author Solutions, LLC — the world leader in supported self-publishing. Titles published through WestBow Press are evaluated for sales potential and considered for publication through Thomas Nelson and Zondervan. For more information, visit westbowpress.com or call (866)-928-1240. For WestBow Press news, click “Like” at facebook.com/WestBowPress and follow @westbowpress on Twitter.
Youan B.-B.C.,University of Missouri - Kansas City
Advanced Drug Delivery Reviews | Year: 2010
The current advances in chronobiology and the knowledge gained from chronotherapy of selected diseases strongly suggest that "the one size fits all at all times" approach to drug delivery is no longer substantiated, at least for selected bioactive agents and disease therapy or prevention. Thus, there is a critical and urgent need for chronopharmaceutical research (e.g., design and evaluation of robust, spatially and temporally controlled drug delivery systems that would be clinically intended for chronotherapy by different routes of administration). This review provides a brief overview of current drug delivery system intended for chronotherapy. In theory, such an ideal "magic pill" preferably with affordable cost, would improve the safety, efficacy and patient compliance of old and new drugs. However, currently, there are three major hurdles for the successful transition of such system from laboratory to patient bedside. These include the challenges to identify adequate (i) rhythmic biomaterials and systems, (ii) rhythm engineering and modeling, perhaps using system biology and (iii) regulatory guidance. © 2010 Elsevier B.V.
Vadlapatla R.K.,University of Missouri - Kansas City
Current pharmaceutical design | Year: 2013
Cancer remains one of the major leading causes of death worldwide. Acquisition of multidrug resistance (MDR) remains a major impediment to successful chemotherapy. As the name implies, MDR is not limited only to one drug but often associated to structurally and functionally unrelated chemotherapeutics. Extensive research and investigations have identified several mechanisms underlying the development of MDR. This process of drug resistance is considered to be multifactorial including decreased drug accumulation, increased efflux, increased biotransformation, drug compartmentalization, modification of drug targets and defects in cellular pathways. In the first part of the review, these pharmacokinetic and pharmacodynamic mechanisms have been described in brief. Although the pathways can act independently, they are more often intertwined. Of the various mechanisms involved, up-regulation of efflux transporters and metabolizing enzymes constitute a major resistance phenotype. This review also provides a general biological overview of important efflux transporters and metabolizing enzymes involved in MDR. Further, synergistic action between efflux transporters and metabolizing enzymes leading to MDR could possibly arise due to two different factors; overlapping substrate specificity and coordinated regulation of their expression. The expression of efflux transporters and metabolizing enzymes is governed by nuclear receptors, mainly pregnane X receptor (PXR). The pharmacological role of PXR and advances in the development of PXR antagonists to overcome MDR are outlined.
Holman C.M.,University of Missouri - Kansas City
Nature Biotechnology | Year: 2012
The fear that human gene patents pose a threat to whole-genome sequencing is based largely on widely held misconceptions. © 2012 Nature America, Inc. All rights reserved.
Bonewald L.F.,University of Missouri - Kansas City
Journal of Bone and Mineral Research | Year: 2011
The last decade has provided a virtual explosion of data on the molecular biology and function of osteocytes. Far from being the "passive placeholder in bone," this cell has been found to have numerous functions, such as acting as an orchestrator of bone remodeling through regulation of both osteoclast and osteoblast activity and also functioning as an endocrine cell. The osteocyte is a source of soluble factors not only to target cells on the bone surface but also to target distant organs, such as kidney, muscle, and other tissues. This cell plays a role in both phosphate metabolism and calcium availability and can remodel its perilacunar matrix. Osteocytes compose 90% to 95% of all bone cells in adult bone and are the longest lived bone cell, up to decades within their mineralized environment. As we age, these cells die, leaving behind empty lacunae that frequently micropetrose. In aged bone such as osteonecrotic bone, empty lacunae are associated with reduced remodeling. Inflammatory factors such as tumor necrosis factor and glucocorticoids used to treat inflammatory disease induce osteocyte cell death, but by different mechanisms with potentially different outcomes. Therefore, healthy, viable osteocytes are necessary for proper functionality of bone and other organs. © 2011 American Society for Bone and Mineral Research.
Agency: NSF | Branch: Standard Grant | Program: | Phase: NSF INCLUDES | Award Amount: 240.75K | Year: 2016
This award supports a conference entitled Accelerating Data-Driven Collaboration for Large-Scale Progress which will support the progress of INCLUDES (Inclusion across the Nation of Communities of Learners that have been Underrepresented for Diversity in Engineering and Science) Launch Pilots toward their broadening participation goals. The issues and challenges affecting the persistence of students of color, students from low-income households, females, and students with disabilities in STEM learning surpass the scope of programs designed to promote awareness of STEM career options. The Launch Pilots will need technical assistance to leverage their strategic plans, become poised for the next level of becoming an Alliance, and ultimately show impact that results in large-scale progress.
The conference will support the Launch Pilots in their broadening participation goals by providing opportunities to (1) develop innovative new ways to gather data and make evidence-based decisions, (2) connect with best practices on the frontiers of data-driven collaboration, and (3) apply new knowledge and innovations to their projects that address societal needs. The overarching design of Data-Driven Collaboration is to facilitate the sharing of ideas, struggles, and promising practices in a collaborative and participatory manner. This will occur by fostering a network improvement community (within and across Launch Pilots), engaging participants in systems thinking and problem-solving through collaborative modeling, and a 2.5-day Public Support and Engagement Lab conference. Launch Pilots who engage support from Data-Driven Collaboration will have a variety of technical assistance services available between November 2016 and April 2017.
Agency: NSF | Branch: Standard Grant | Program: | Phase: COMPUTING RES INFRASTRUCTURE | Award Amount: 772.06K | Year: 2016
The aim of this NSF CRI-II-NEW project is to develop a testbed for computer aided design (CAD) simulations, experimental metrology, and software and hardware calibrations to support cross-layer evaluation of novel nanoscale 3D heterogeneous integration of CMOS and post-CMOS technologies. Proposed tools and equipment acquisitions and sustainment will allow bottom-up evaluations from materials, fundamental physics, and experimental metrology to device and circuits to large-scale systems. The proposed infrastructure is unique and will enable thorough evaluation of new 3D heterogeneous integration concepts with accuracy only parallel to full-scale experimental prototyping. It will directly impact the nano-electromagnetics, nano-device, circuits, 3D IC and manufacturing research directions, and will also have significant impact on the big data analytics, renewable energy, smart-city, RF and electromagnetics research initiatives in Computer Science and Electrical Engineering (CSEE) department at University of Missouri-Kansas City (UMKC). The testbed will not only facilitate transformative research, but will also allow broad ranging educational and outreach activities such as new undergraduate and graduate curriculum development with lab modules, training and mentoring of research students, research dissemination thorough forums and seminars, development of online repositories and online labs, and nanotechnology awareness for K-12 students through summer workshops. The boarder impact of this project is that the proposed infrastructure will provide unique opportunities for research, education and community outreach in the fields of nanomaterials, nanodevice, nanocircuit, biosensing, heterogonous integration, and nanomanufacturing.
The research focus of this collaborative project will be to develop nanoscale heterogeneous 3D integration and testing framework for bio-sensing and computing applications leveraging novel materials, devices, circuits and integration schemes. 3D integration provides opportunities to realize systems with heterogeneous layers, such as bio-analytical device and mixed-signal information processing layers that can be vertically stacked and electrically connected through dense vias. However, such implementation with CMOS is challenging due to CMOS?s scaling limits, noise coupling between dissimilar analog and digital circuit components and limitations of die-die or layer-layer stacking. We propose a new 3-D heterogeneous integration approach that overcomes challenges by utilizing new materials such as Carbon Nanotube, MoS2, and nanoscale geometry to realize highly sensitive bio-sensors for bio-molecule detections, scalable 2-D material based ultra-low power devices that exhibit FET like switching and Negative Differential Resistance (NDR) for seamless integration of signal processing and logic components, and monolithic 3-D integration techniques with dense vias. Initial projections reveal significant benefits for such heterogeneous integration over conventional 2-D CMOS based multi-chip based approaches. If realized, this can be game-changing for mixed-signal ASICs, and as well for bio-medical applications such as point-of-care and lab-on-a-chips.
Agency: NSF | Branch: Standard Grant | Program: | Phase: ELECTRONIC/PHOTONIC MATERIALS | Award Amount: 308.17K | Year: 2016
Nontechnical description: This project is focused on the effect of hydrogenation on the microwave absorption properties of titanium dioxide nanoparticles. These nanoparticles have the potential to advance the field of microwave absorption, leading to a number of practical applications in areas such as telecommunication, spacecraft communication, wireless communication, radar detection, satellite navigation, etc. The research team aims to understand the underlying mechanisms of how hydrogenation affects the microwave absorption of inorganic nanoparticles with various phase compositions and surface morphologies. The principal investigator provides training opportunities for graduate and undergraduate students and popularizes his research efforts and results via various outreach activities, reaching to the local community and underrepresented groups. He develops online courses focused on electronic and photonic properties of these materials, which are available to the public.
Technical description: This project tackles newly observed phenomena by the PIs group of significantly increased microwave absorption in hydrogenated titanium dioxide nanoparticles that cannot be explained with traditional mechanisms. The project goal is to reveal the underlying mechanisms and to elucidate the effects of hydrogenation by comprehensive approach, studying structural, chemical, optical, electronic, dielectric and microwave absorption properties by employing various characterization methods such as X-ray diffraction, high-resolution transmission electron microscopy, Raman spectroscopy, ultraviolet-visible absorption spectroscopy, Fourier transform infrared spectroscopy, (valence band) X-ray photoelectron spectroscopy, and a transmission line technique with a network analyzer. The project integrates the research activities with educational opportunities for graduate, undergraduate and high-school students.
Agency: NSF | Branch: Standard Grant | Program: | Phase: SOFTWARE & HARDWARE FOUNDATION | Award Amount: 461.11K | Year: 2016
Over the last sixty years silicon based integrated circuit technologies have been successfully meeting the demands of higher performance and lower energy consumption through the miniaturization of the transistor and circuit dimensions. As the conventional devices and materials are now approaching their fundamental physical limits, new devices and circuits and materials need to be investigated for the next generation logic, memory, sensor and energy harvesting applications. Within this framework, the proposed research on a new nanoscale ultra-low-power electronic device makes use of convergence of technologies in advanced computing, electronic engineering, mathematics, physics, chemistry and information-theory. This EPSCoR initiative would directly or indirectly impact a large number of students of the PIs institution, and an even larger number of local high school and pre-collegiate students through the Kansas City STEM Alliance, for which the PI plans to develop a summer bridge program to promote nanotechnology education.
From a technical standpoint the project plans to develop a new field effect transistor (FET) technology to achieve an effective negative capacitance (NC) inside the transistor structure by utilizing ferroelectric materials. It has recently been reported that ferroelectric materials can provide a negative capacitance that can be the solutions to many of the challenges of nanoelectronics. While many contemporary researchers are investigating ways to exploit this NC effect to break the performance and energy efficiency barriers of the existing silicon based transistors, the proposed effort combines the concept of the emerging negative capacitance based field effect transistor (NCFET) and the conventional silicon-on-insulator (SOI) technologies.