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Braga, Portugal

Mateus-Pinheiro A.,University of Minho
Translational psychiatry | Year: 2013

Impairment of hippocampal neurogenesis has been associated with the expression of depressive-like symptoms and some studies have suggested neurogenesis as a critical factor in the normalization of behavior by antidepressant (AD) drugs. This study provides robust evidence that ongoing neurogenesis is essential for the maintenance of behavioral homeostasis and that its pharmacological arrest precipitates symptoms commonly found in depressed patients. Further, the incorporation of newly born neurons and astrocytes into the preexisting hippocampal neurocircuitry is shown to be necessary for the spontaneous recovery from the adverse effects of stress and for long-term benefits of AD treatments. Source


Peres N.M.R.,University of Minho
Reviews of Modern Physics | Year: 2010

An introduction to the transport properties of graphene combining experimental results and theoretical analysis is presented. In the theoretical description simple intuitive models are used to illustrate important points on the transport properties of graphene. The concept of chirality, stemming from the massless Dirac nature of the low-energy physics of the material, is shown to be instrumental in understanding its transport properties: the conductivity minimum, the electronic mobility, the effect of strain, the weak (anti)localization, and the optical conductivity. © 2010 The American Physical Society. Source


Pacheco-Torgal F.,University of Minho
Construction and Building Materials | Year: 2014

With an overall budget of around 70,000 million € for the next seven years (2014-2020) the EU Framework Programme for research and Innovation-Horizon 2020 constitutes the most important financial instrument for research and innovation in the world. Sustainable development is of paramount significance for Horizon 2020 through climate action and resource efficiency, which will represent at least 60% of the overall budget. This sustainability focus could have a strong impact on the future of the European construction industry and also being an opportunity for the development and commercialization of eco-efficient construction and building materials. This article addresses the case of materials for energy efficiency and materials capable of reusing a high waste content. Nanotech energy efficiency related building materials has the potential to become a hot research area being promoted and funded as a Key Enabling Technology-KET. © 2013 Elsevier Ltd. All rights reserved. Source


Patent
University of Minho and Catholic University of Leuven | Date: 2011-11-03

The present invention relates to a polypeptide with endolysin activity comprising an amino acid sequence according to SEQ ID No. 1 and fragments or derivatives thereof, or fusion proteins derived thereof. Moreover, the present invention relates to nucleic acid molecules encoding said polypeptide or fusion protein, vectors comprising said nucleic acid molecules and host cells comprising either said nucleic acid molecules or said vectors. In addition, the present invention relates to said polypeptide, fragment, derivative or fusion protein for use as a medicament, in particular for the treatment or prevention of Gram-negative bacterial infections, as diagnostic means, as cosmetic substance or as sanitizing agent. The present invention also relates to the use of said polypeptide, fragment, derivative or fusion protein for the treatment or prevention of Gram-negative bacterial contamination of foodstuff, of food processing equipment, of food processing plants, of surfaces coming into contact with foodstuff, of medical devices, of surfaces in hospitals and surgeries. Furthermore, the present invention relates to a pharmaceutical composition comprising said polypeptide, fragment, derivative or fusion protein.


The present invention refers to the development of a Peptide Nucleic acid (PNA) probe for the detection of the

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