Mannheim, Germany
Mannheim, Germany

The University of Mannheim , also known as UMA, is a public research university situated in Mannheim, Baden-Württemberg, Germany. Founded in 1967 the university has its origins in the 1763 established Theodoro Palatinae , which was founded by the later Duke of Bavaria Charles Theodor, as well as the Handelshochschule , founded by Mannheim's senior mayor Otto Beck and Heidelberg's professor for Economics Eberhard Gothein in 1907. The University offers a wide range of undergraduate and graduate programs as well as Ph.D degrees within business administration, economics, law, social science, humanities, mathematics, computer science and information systems – all with an interdisciplinary and international focus. The University of Mannheim's campus is located in the city center of Mannheim and mainly centers on its main campus – the Mannheim Palace . The university has around 11,880 full-time students, 800 scholars enrolled, 800 academic staff and a total income of more than €115 million in 2012. It is organized into 5 academic departments and 2 academic colleges.The UMA is considered to have the by far best and most prestigious business school in Germany and is consistently ranked #1 in national university rankings and among the top business schools worldwide for its business administration and economics programs. Moreover, the university's programs for social science, politics as well as business informatics rank nationwide within the Top 3 and its programs for law and computer science within the Top 10. The 2012/2013 QS World University Rankings ranked the UMA among the best one hundred universities within the disciplines of Social science & Management, Accounting and Economics & Econometrics, as well as among the Top 50 universities within the discipline of Political science. Furthermore, the University of Mannheim is placed 83rd with regard to global employer reputation.The University of Mannheim is a member of the German Universities Excellence Initiative, the International Association of Universities, the European Network for Training Economic Research, the German Research Foundation , and it is accredited by the European Quality Improvement System , the Association to Advance Collegiate Schools of Business as well as the Association of MBAs . Wikipedia.

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Agency: European Commission | Branch: FP7 | Program: CP-IP | Phase: SSH.2013.1.2-1 | Award Amount: 6.38M | Year: 2014

The multi-disciplinary CUPESSE project carries out a comparative analysis of both the demand and supply side of youth unemployment in ten Member States of the EU and Associated Countries (i.e. Austria, Czech Republic, Denmark, Germany, Hungary, Italy, Spain, Switzerland, Turkey, and the United Kingdom). These ten countries represent the main empirical scope of the project, but whenever possible, the analysis is extended to include all European countries. CUPESSE has five main objectives. The first objective is to obtain a more refined understanding of the supply side of young adults employment by concentrating on how the inter-generational accumulation of social capital and cultural capital in the context of family organisation influences the economic self-sufficiency and entrepreneurship of young people in Europe. The second objective is to examine how supply-side factors and demand-side factors affect the unemployment of young adults. In this context we are particularly interested in the degree to which the attitudes and skills of young adults match with employers demands. The third objective is to understand the implications of young adults unemployment in the longer term, including the effects on the unemployed individuals and on society as a whole. The fourth objective is to investigate the degree to which flexicurity policies, policies supporting business start-ups and self-employment, and policies promoting education and training platforms are embraced by the European states and to assess their impacts on young adults unemployment. The fifth objective of the CUPESSE project is to present ideas for new policy measures and formulate strategy for overcoming youth unemployment in Europe. To attain this goal, the project brings together theoretical perspectives and methodological approaches from four academic disciplines, namely economics, political science, psychology, and sociology.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: EURO-4-2014 | Award Amount: 2.50M | Year: 2015

The goal of the EUENGAGE Project is twofold: first, to inquire into the current tensions between supranational EU governance and popular mobilisation at the national level, critically questioning EU-driven policies and EU legitimacy; and second, to propose remedial actions based on sound empirical research on the relationship between public opinion, national and supranational political elites. The medium to long-term evolutionary trend of the EU system of supranational governance has already in the past given rise to a manifestation of problems. It has become clear that the pace of integration proposed from the top, and some side-effects of integrationausterity, transnational redistribution, economic insecurity, immigrationare difficult to accept for large parts of Europes citizens. This misalignment is obviously a crucial issue for any system of governance that aims - as the European Union has repeatedly affirmed - to be inspired by democratic principles. The EUENGAGE project takes seriously the present state of affairs and identifies in the conflicting messages emanating from the functioning of political representation a critical and urgent problem for the future of the EU. The EUENGAGE proposes to set up an interactive, dynamic, multilevel and replicable quasi-experimental research design. Using a variety of instruments and techniques, this design will allow us not only to study the process of representation in vivo, but also to test experimentally how innovative and efficient interactions between citizens and politicians can increase citizens awareness of the common problems of the Union, and the ability of the European leadership to respond innovatively to the discontent of public opinion.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: REFLECTIVE-3-2015 | Award Amount: 2.45M | Year: 2016

COHESIFY will assess the contribution of Cohesion policy to citizens identification with the EU and produce a new strategy to communicate EU Cohesion policy to citizens. It will assess how and to what extent EU Cohesion policy affects citizens perceptions of and identification with the European Union. The project will focus on three inter-related issues: (1)the identity(ies)of people in EU regions in EU, national, regional and local contexts; (2)the governance, communication and impacts of Cohesion policy, including citizens perceptions of the policy and identification with the EU, and (3)what is needed to make Cohesion policy more effective in terms of peoples perceptions of the policy and the EU more generally. A mixed-methods design will be adopted to study the relationship between Cohesion policy, policy performance and attitudes to the EU, distinguishing between different levels of governance and types of actors-from those involved in programme design and implementation to final beneficiaries and the wider public. The communication channels of Cohesion policy influence will be examined, distinguishing between public communication and political and social communication. COHESIFY will fill a key gap in knowledge for EU and national/regional policymakers and interested stakeholders. The outputs will inform Cohesion policy communication strategies at the EU, Member State and regional levels, enabling communication efforts to adapt to local and regional realities to maximise their impact - to increase the civic appreciation of Cohesion policy and to improve regional policy relevance and efficiency. The Consortium comprises academic institutions and SMEs across a range of EU Member States with complementary disciplinary backgrounds of understanding EU Cohesion policy, complemented by applied SME expertise in communication strategies and tools for engaging with citizens and the various political structures at EU, national, regional and local levels.

Agency: European Commission | Branch: H2020 | Program: RIA | Phase: GV-8-2015 | Award Amount: 6.15M | Year: 2016

ELECTRIFIC will revolutionise how electric vehicles are integrated into power grid and users life. The fundamental premise on which the project will work that significant improvements to electromoblity can be unlocked by increasing coordination of all the actors in the electromobility ecosystem. To this end, the project will deliver novel techniques and ICT tools for enabling such coordination at all levels of the ecosystem. At the grid level, the project will develop new smart charging stations capable of dynamically controlling charging rate, maximizing the use of renewables and making as grid-friendly as possible. At level of EV users, the project will develop advanced driver assistance services that help and motivate the users plan travel and charging in a way that is convenient and yet respects potential constraints on charging capacity. Finally, at the EV fleet level, the project will develop management tools that help to optimise fleet operations, maximising battery lifetime and minimising charging costs. ELECTRIFIC comprises a balanced consortium of experienced research partners, energy providers and innovative electromobility SMEs. The results of the project will disseminated in the scientific community and rolled out to commercial use from e-bikes to e-buses, from private owners to government services and including cross-border mobility.

Early assessment of response at 3 months of tyrosine kinase inhibitor treatment has become an important tool to predict favorable outcome. We sought to investigate the impact of relative changes of BCR-ABL transcript levels within the initial 3 months of therapy. In order to achieve accurate data for high BCR-ABL levels at diagnosis, beta glucuronidase (GUS) was used as a reference gene. Within the German CML-Study IV, samples of 408 imatinib-treated patients were available in a single laboratory for both times, diagnosis and 3 months on treatment. In total, 301 of these were treatment-naïve at sample collection. Results: (i) with regard to absolute transcript levels at diagnosis, no predictive cutoff could be identified; (ii) at 3 months, an individual reduction of BCR-ABL transcripts to the 0.35-fold of baseline level (0.46-log reduction, that is, roughly half-log) separated best (high risk: 16% of patients, 5-year overall survival (OS) 83% vs 98%, hazard ratio (HR) 6.3, P=0.001); (iii) at 3 months, a 6% BCR-ABLIS cutoff derived from BCR-ABL/GUS yielded a good and sensitive discrimination (high risk: 22% of patients, 5-year OS 85% vs 98%, HR 6.1, P=0.002). Patients at risk of disease progression can be identified precisely by the lack of a half-log reduction of BCR-ABL transcripts at 3 months.Leukemia advance online publication, 3 June 2014; doi:10.1038/leu.2014.153.

Henzler T.,University of Mannheim
AJR. American journal of roentgenology | Year: 2012

OBJECTIVE: Various applications for dual-energy CT (DECT) have been investigated and have shown substantial clinical benefits. However, only limited data are available regarding the radiation dose associated with DECT imaging. The purpose of this article is to review the available literature regarding the radiation dose associated with DECT imaging applications in comparison with conventional single-energy CT techniques. CONCLUSION: The rediscovery of DECT and the increasing availability of this technique on clinical CT systems have opened new dimensions for CT. The advanced spectral differentiation of materials within the human body as well as the selective visualization or subtraction of iodinated contrast material or xenon provides both advanced visualization of disease-specific molecular substrates as well as additional functional information within a single scan.

Setzer S.,University of Mannheim
International Journal of Computer Vision | Year: 2011

We examine the underlying structure of popular algorithms for variational methods used in image processing. We focus here on operator splittings and Bregmanmethods based on a unified approach via fixed point iterations and averaged operators. In particular, the recently proposed alternating split Bregman method can be interpreted from different points of view-as a Bregman, as an augmented Lagrangian and as a Douglas-Rachford splitting algorithm which is a classical operator splitting method.We also study similarities between this method and the forward-backward splitting method when applied to two frequently used models for image denoising which employ a Besov-norm and a total variation regularization term, respectively. In the first setting, we show that for a discretization based on Parseval frames the gradient descent reprojection and the alternating split Bregman algorithm are equivalent and turn out to be a frame shrinkage method. For the total variation regularizer, we also present a numerical comparison with multistep methods. © Springer Science+Business Media, LLC 2010.

Rost K.,University of Mannheim
Research Policy | Year: 2011

There is an ongoing debate in innovation research as to which type of social capital is more conducive to innovation: structural holes as proposed by Burt or network closure as proposed by Coleman. Although Coleman focused on the quality of relationships, Burt argued that the structural configuration of relationships was more important. I argue that, instead of being alternative substitutes, Burt's social capital theory complements Coleman's theory. More precisely, I demonstrate that, in the presence of strong ties, weak network architectures (structural holes or a peripheral network position) leverage the strength of strong ties in the creation of innovation. This implies that weak network architectures have no value without strong ties, whereas strong ties have some value without weak network architectures but are leveraged by this type of structure. The findings indicate that innovation research tends to overestimate the impact of weak network architectures in the creation of innovation. By pointing to the necessity of strong ties, the results may be of particular interest for research on open innovation. They suggest that open innovation will not work if closed innovation principles are pushed back. © 2010 Elsevier B.V. All rights reserved.

Kaehler G.,University of Mannheim
The British journal of surgery | Year: 2013

Experimental studies and small anecdotal reports have documented the potential and feasibility of transgastric appendicectomy. This paper reports the results of the new technique in a selected group of patients. From April 2010 transgastric appendicectomy was offered to all patients with acute appendicitis, but without generalized peritonitis or local contraindications. Of 111 eligible patients 15 agreed to undergo the transgastric operation. After conversion of the first case to laparoscopy because of severe inflammation and adhesions, the following 14 consecutive transgastric procedures were completed. Two patients with initial peritonitis required laparoscopic lavage 4 days after transgastric appendicectomy, but no leaks were detected at the appendiceal stump or stomach. These preliminary results have shown the feasibility of this innovative procedure. Additional studies, however, are required to demonstrate the specific advantages and disadvantages of this approach, and define its role in clinical surgery. © 2013 British Journal of Surgery Society Ltd. Published by John Wiley & Sons Ltd.

Agency: European Commission | Branch: FP7 | Program: ERC-SG | Phase: ERC-SG-SH2 | Award Amount: 1.49M | Year: 2014

The objective of this project is to uncover and explain the escalation and non-escalation of repression and intra-state armed conflict by analyzing how characteristics of the government and its formal and informal security apparatus shape the dynamics of such violence, paying particular attention to the role of monitoring and accountability. RATE analyzes when and under what conditions what types of human rights violations lead to the escalation or deterrence of further repression and armed conflict. Although there has been substantial increase in research on civil war, we know surprisingly little about the dynamics that escalate armed conflict within country-borders and those that prevent an escalation and what role human rights violations and informal armed actors play in those dynamics. While civil wars are a relatively rare occurrence, repression and human rights violations are not. What can this tell us about the link between human rights violations and repression? What leads to the escalation of political violence, increasing the severity and breadth of repression? What hampers the escalation of repression into civil war? Does the avoidance of civil war come at the cost of increased repression? The proposed project produces new data on personal integrity rights and civil liberties, disaggregated by type, intensity, perpetrator, as well as time and space, and on pro-government militias to investigate the conditions under which repression escalates and how monitoring and accountability of formal and particularly informal armed actors affect these escalation processes. It analyzes whether particular human rights violations prevent the escalation of violence by compromising the personal security of the people living in that country. An exploratory case study and agent-based models will be used to refine the theoretical argument, which will then be tested on the new data with cross-national quantitative analyses and three qualitative comparative case studies.

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