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Manchester, United Kingdom

The University of Manchester is a large research university situated in the city of Manchester, England. Manchester University, as it is commonly known, is a public university formed in 2004 by the merger of the University of Manchester Institute of Science and Technology and the Victoria University of Manchester . Manchester is a member of the worldwide Universities Research Association group, the Russell Group of British research universities and the N8 Group. The University of Manchester is regarded as a "red brick university", and was a product of the civic university movement of the late 19th century. It formed a constituent part of the federal Victoria University between 1880, when it received its royal charter, and 1903-1904, when it was dissolved.The main campus is south of Manchester city centre on Oxford Road. In 2012, the university had around 39,000 students and 10,400 staff, making it the largest single-site university in the United Kingdom. The University of Manchester had an income of £827 million in 2012–13, of which £200 million was from research grants and contracts.In the 2008 Research Assessment Exercise, Manchester came third in terms of research power and eighth for grade point average quality when including specialist institutions. More students try to gain entry to the University of Manchester than to any other university in the country, with more than 60,000 applications for undergraduate courses. According to the 2012 Highfliers Report, Manchester is the most targeted university by the Top 100 Graduate Employers.The University of Manchester is ranked 30th in the world by QS World University Rankings. In the 2014 Academic Ranking of World Universities, Manchester is ranked 38th in the world and 5th in the UK. It is ranked 52nd in the world and 12th in Europe in the 2014 Times Higher Education World University Rankings.The university owns and operates major cultural assets such as the Manchester Museum, Whitworth Art Gallery, John Rylands Library and Jodrell Bank Observatory which includes the Grade I listed Lovell Telescope.The University of Manchester has 25 Nobel laureates among its past and present students and staff, the fourth-highest number of any single university in the United Kingdom. Four Nobel laureates are currently among its staff – more than any other British university. Wikipedia.

Novoselov K.S.,University of Manchester
Reviews of Modern Physics | Year: 2011

Much like the world described in Abbott's Flatland, graphene is a two-dimensional object. And, as "Flatland" is "a romance of many dimensions," graphene is much more than just a flat crystal. It possesses a number of unusual properties which are often unique or superior to those in other materials. In this brief lecture I would like to explain the reason for my (and many other people's) fascination with this material, and invite the reader to share some of the excitement I've experienced while researching it. © 2011 American Physical Society. Source

Pilaftsis A.,University of Manchester
Physical Review D - Particles, Fields, Gravitation and Cosmology | Year: 2016

Recently, the LHC collaborations, ATLAS and CMS, have announced an excess in the diphoton channel with local significance of about 3σ around an invariant mass distribution of ∼750 GeV, after analyzing new data collected at center-of-mass energies of s=13 TeV. We present a possible physical interpretation of such a signature, within the framework of a minimal UV-complete model with a massive singlet pseudoscalar state a that couples to a new TeV-scale colored vectorlike fermion F, whose hypercharge quantum number is a non-zero integer. The pseudo-scalar state a might be a heavy pseudo-Goldstone boson, such as a heavy axion, which decays into two photons and whose mass lies around the excess region. The mass of the CP-odd state a and its coupling to F may be due to nonperturbative effects, which can break the original Goldstone shift symmetry dynamically. The possible role that the heavy axion a can play in the radiative generation of a seesaw Majorana scale and in the solution to the so-called strong CP problem is briefly discussed. © 2016 American Physical Society. Source

Grencis R.K.,University of Manchester
Annual Review of Immunology | Year: 2015

Helminth parasites are a highly successful group of pathogens that challenge the immune system in a manner distinct from rapidly replicating infectious agents. Of this group, roundworms (nematodes) that dwell in the intestines of humans and other animals are prevalent worldwide. Currently, more than one billion people are infected by at least one species, often for extended periods of time. Thus, host-protective immunity is rarely complete. The reasons for this are complex, but laboratory investigation of tractable model systems in which protective immunity is effective has provided a mechanistic understanding of resistance that is characterized almost universally by a type 2/T helper 2 response. Greater understanding of the mechanisms of susceptibility has also provided the basis for defining host immunoregulation and parasite-evasion strategies, helping place in context the changing patterns of immunological disease observed worldwide. © 2015 by Annual Reviews. All rights reserved. Source

Klingenberg C.P.,University of Manchester
Nature Reviews Genetics | Year: 2010

Morphological traits have long been a focus of evolutionary developmental biology ('evo-devo'), but new methods for quantifying shape variation are opening unprecedented possibilities for investigating the developmental basis of evolutionary change. Morphometric analyses are revealing that development mediates complex interactions between genetic and environmental factors affecting shape. Evolution results from changes in those interactions, as natural selection favours shapes that more effectively perform some fitness-related functions. Quantitative studies of shape can characterize developmental and genetic effects and discover their relative importance. They integrate evo-devo and related disciplines into a coherent understanding of evolutionary processes from populations to large-scale evolutionary radiations. © 2010 Macmillan Publishers Limited. All rights reserved. Source

Wolstencroft K.,University of Manchester
Nucleic acids research | Year: 2013

The Taverna workflow tool suite (http://www.taverna.org.uk) is designed to combine distributed Web Services and/or local tools into complex analysis pipelines. These pipelines can be executed on local desktop machines or through larger infrastructure (such as supercomputers, Grids or cloud environments), using the Taverna Server. In bioinformatics, Taverna workflows are typically used in the areas of high-throughput omics analyses (for example, proteomics or transcriptomics), or for evidence gathering methods involving text mining or data mining. Through Taverna, scientists have access to several thousand different tools and resources that are freely available from a large range of life science institutions. Once constructed, the workflows are reusable, executable bioinformatics protocols that can be shared, reused and repurposed. A repository of public workflows is available at http://www.myexperiment.org. This article provides an update to the Taverna tool suite, highlighting new features and developments in the workbench and the Taverna Server. Source

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