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Kuala Lumpur, Malaysia

The University of Malaya is a public research university located in Kuala Lumpur, Malaysia. It is the oldest and most esteemed university in Malaysia. The university's name was abbreviated as Malaya during the pre-independence period.The university was founded in 1949 as a public-funded tertiary institution. Today, it has more than 2,500 faculty members. In 2012, UM was granted autonomy status by the Ministry of Higher Education.In 2014, the QS World University Rankings has ranked UM at the 151st place of the world. Wikipedia.

A bibliographic review of the crystallographic literature has been conducted on gold(I) compounds bearing functional groups capable of forming conventional hydrogen bonding interactions, namely, primary amide, secondary amide and carboxylic acid. The clear majority of structures featured hydrogen bonding interactions leading to well defined zero- or one-dimensional supramolecular architectures; rarely were two-dimensional architectures formed. Conversely, aurophilic, Au⋯Au, were the exception rather than the rule. This observation is correlated with steric hindrance: small atoms associated via directional hydrogen bonding compared with encumbered gold-atom environments (due to bulky ligands). Amide-{⋯HNCO}2 and carboxylic acid-{⋯HOCO}2 synthons featured in significantly more of the gold(I) structures compared with all-organic systems, particularly for non-ionic structures where charged-assisted hydrogen bonding precluded the formation of these cyclic synthons. This suggests a crystal engineering strategy of functionalising metal complexes with hydrogen bonding potential to improve opportunities of rational design of crystal structures. © 2014. Source

Saidur R.,University of Malaya
Energy Education Science and Technology Part A: Energy Science and Research | Year: 2010

Chillers consume a major share of total air conditioning energy use in commercial and industrial buildings for space conditioning to get thermal comfort for a country. In this paper, energy consumption by chillers has been estimated using data collected by walkthrough energy audit for Malaysian office buildings. It has been found that chillers use about 42,285MWh and 84,569MWh of electric energy for 50% and 100% loadings in an institutional buildings. As chillers are major energy users, energy savings measure such as use of energy efficient chillers and VSDs in chillers cooling load reductions have been applied to reduce their energy consumptions. It has been found that 90MWh-896MWh of energy can be saved for using energy efficient chillers for different percentage of loadings. Along with energy savings, US$57,314 as a bill savings can be achieved for high efficient chillers for 50% chillers loading. Study found that 35,975 MWh energy and US$2,302,431 bill can be saved for 60% of speed reductions using VSD. It was also found that payback periods for this energy saving option for chillers are economically viable. Along with energy savings, emission reductions and cost of avoided carbon associated with energy savings have been estimated and presented in this paper. © Sila Science. Source

Wong K.T.,University of Malaya
Acta Neuropathologica | Year: 2010

In the last few decades, there is an increasing emergence and re-emergence of viruses, such as West Nile virus, Enterovirus 71 and henipaviruses that cause epidemic viral encephalitis and other central nervous system (CNS) manifestations. The mortality and morbidity associated with these outbreaks are significant and frequently severe. While aspects of epidemiology, basic virology, etc., may be known, the pathology and pathogenesis are often less so, partly due to a lack of interest among pathologists or because many of these infections are considered "third world" diseases. In the study of epidemic viral encephalitis, the pathologist's role in unravelling the pathology and pathogenesis is critical. The novel henipavirus infection is a good example. The newly created genus Henipavirus within the family Paramyxoviridae consists of two viruses, viz., Hendra virus and Nipah virus. These two viruses emerged in Australia and Asia, respectively, to cause severe encephalitides in humans and animals. Studies show that the pathological features of the acute encephalitis caused by henipaviruses are similar and a unique dual pathogenetic mechanism of vasculitis-induced microinfarction and parenchymal cell infection in the CNS (mainly neurons) and other organs causes severe tissue damage. Both viruses can cause relapsing encephalitis months and years after the acute infection due to a true recurrent infection as evidenced by the presence of virus in infected cells. Future emerging viral encephalitides will no doubt continue to pose considerable challenges to the neuropathologist, and as the West Nile virus outbreak demonstrates, even economically advanced nations are not spared. © 2010 Springer-Verlag. Source

Tiekink E.R.T.,University of Malaya
Dalton Transactions | Year: 2012

Despite being disparaged for their malodorous and toxic demeanour, compounds of selenium, a bio-essential element, and tellurium, offer possibilities as therapeutic agents. Herein, their potential use as drugs, for example, as anti-viral, anti-microbial, anti-inflammatory agents, etc., will be surveyed along with a summary of the established biological functions of selenium. The natural biological functions of tellurium remain to be discovered. © 2012 The Royal Society of Chemistry. Source

Tiekink E.R.T.,University of Malaya
Chemical Communications | Year: 2014

In this Viewpoint, the impact of the paper published by Gautam R. Desiraju and Angelo Gavezzotti (J. Chem. Soc., Chem. Commun., 1989, 621) upon the development of Crystal Engineering, now recognised a key discipline in contemporary chemical/pharmaceutical/materials science, is discussed. © 2014 the Partner Organisations. Source

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