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Chennai, India

The University of Madras is a public state university in Chennai, Tamil Nadu. Established in 1857, it is one of the oldest and premier universities in India. The university was incorporated by an act of the Legislative Council of India.It is a collegiate research university and has six campuses in the city viz., Chepauk, Marina, Guindy, Taramani, Maduravoyal and Chetpet. The university has 68 teaching and research departments grouped under 18 schools, covering languages, humanities, science, technology and medicine.The National Assessment and Accreditation Council has conferred 'five star' accreditation to the university and it has been given the status of 'University with Potential for Excellence' by the University Grants Commission. Wikipedia.


Kumar C.,University of Madras
Journal of Materials Science: Materials in Electronics | Year: 2011

The preparation of Calcium copper titanate (CCTO) nanopowder was carried out by a sol-gel self combustion method. The X-ray diffraction analysis indicated that the samples calcined at 800 °C were fully crystallized in the CCTO phase. The results of atomic force microscope showed the particles size of CCTO was in the range of 60-80 nm. The absorption bands corresponding to vibrations of Cu-O, Ti-O-Ti and νCa-O were observed at 512, 450 and 562 cm -1 using FTIR. The samples sintered at 950 °C showed the densities as high as 97% of theoretical density. The grain sizes of sintered pellets were determined by HRSEM. The dielectric properties of prepared samples were studied by LCR meter. © 2010 Springer Science+Business Media, LLC. Source


Ramanibai R.,University of Madras | Velayutham K.,University of Madras
Research in Veterinary Science | Year: 2015

Larvicidal activity of synthesized Ag nanoparticles using 2,7.bis[2-[diethylamino]-ethoxy]fluorence isolate from the Melia azedarach leaves against Aedes aegypti and Culex quinquefasciatus. Six fractions were collected and concentrated, fraction three showed a single spot on TLC which was found to be a pure compound. The structures were elucidated by analyses of UV, MS, and NMR spectral data. The maximum mortality was fluorence against A.aegypti and C.quinquefasciatus (LC50=7.94, LC90=23.82ppm and LC50=13.58 and LC90=40.03ppm). The synthesized nanoparticles were characterized and confirmed as Ag nanoparticles by using UV-visible spectroscopy, XRD and HRTEM analysis. The maximum activity was observed in synthesized AgNPs against A.aegypti and C.quinquefasciatus (LC50=4.27 and 3.43μg/mL; LC90=12.61 and 10.29μg/mL). Rephrase test was studied to analyze the toxicological effects of Mesocyclops pehpeiensis for 24h at synthesized AgNPs. This method is considered as an innovative alternative approach that can be used to control mosquitoes. © 2014 . Source


Ashokkumar V.,University of Madras | Rengasamy R.,University of Madras
Bioresource Technology | Year: 2012

Three different strains of colonial green alga Botryococcus bruanii Kutz. AP103, AP104 and AP105 were isolated from the freshwater lake Kolleru, Andhra Pradesh, India. The morphological features of these three isolates were studied under laboratory conditions. Molecular identification of the strains was carried out using 18S rRNA analysis and their systematic position was confirmed to species level as B. braunii. Among these isolates, B. braunii AP103 recorded highest biomass concentration of 1.7±0.12gL -1, 17% lipids, 17% proteins, 32% carbohydrates and 13% hydrocarbons under laboratory condition. Under open raceway pond AP103 produced a biomass concentration of 1.8±0.13gL -1, 19% lipids, 33% carbohydrates, 18% proteins and 11% hydrocarbons. The hydrocarbons profile showed the presence of heptadecane (34%) and hexadecane (12.5%). Oleic (25.7%), linolenic (34.26%) and palmitic (9.42%) acids were the major fatty acids present in the lipids extracted from AP103. © 2011 Elsevier Ltd. Source


Rajeshwaran G.G.,University of Madras | Mohanakrishnan A.K.,University of Madras
Organic Letters | Year: 2011

A synthesis of staurosporine aglycon and its analogs was achieved in a 28-36% overall yield starting from 2-methylindole. The prominent key steps for the synthesis of the indolocarbazole alkaloids involved electrocyclization and nitrene insertion reactions. © 2011 American Chemical Society. Source


Chronic exposure of pancreatic β-cells to supraphysiologic glucose causes adverse β-cell dysfunction. Thus, the present study was aimed to investigate the hypothesis that oral administration of resveratrol attenuates hyperglycemia, proinflammatory cytokines and antioxidant competence and protects β-cell ultrastructure in streptozotocin-nicotinamide-induced diabetic rats. Oral administration of resveratrol (5 mg/kg body weight) to diabetic rats for 30 days showed a significant decline in the levels of blood glucose, glycosylated hemoglobin (HbA1c), TNF-α, IL-1β, IL-6, NF-κB p65 unit and nitric oxide (NO) with concomitant elevation in plasma insulin. Further, resveratrol treated diabetic rats elicited a notable attenuation in the levels of lipid peroxides, hydroperoxides and protein carbonyls in both plasma and pancreatic tissues. The diminished activities of pancreatic superoxide dismutase (SOD), catalase, glutathione peroxidase (GPx) and glutathione-S- transferase (GST) as well as the decreased levels of plasma ceruloplasmin, vitamin C, vitamin E and reduced glutathione (GSH) in diabetic rats were reverted to near normalcy by resveratrol administration. Based on histological and ultrastructural observations, it is first-time reported that the oral administration of resveratrol may effectively rescue β-cells from oxidative damage without affecting their function and structural integrity. The results of the present investigation demonstrated that resveratrol exhibits significant antidiabetic potential by attenuating hyperglycemia, enhancing insulin secretion and antioxidant competence in pancreatic β-cells of diabetic rats. © 2010 Wiley-Liss, Inc. Source

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