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University of Lyon

Lyon, France
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News Article | April 25, 2017
Site: www.eurekalert.org

Patients who suffer a first broken bone due to underlying osteoporosis are at two- to threefold risk of subsequent fractures -- which can lead to a host of serious outcomes such as pain, disability, loss of quality of life and even premature death. Given this danger, medical guidelines consistently recommend that fracture patients aged 50 or over, receive intervention that includes assessment of bone status and evaluation of fracture risk. However, despite clear medical recommendations, studies have shown that only approximately 20% of fracture patients are offered adequate post-fracture assessment and care. Would it be more effective to empower the patients themselves to demand testing and care? This question was asked by investigators from Lyon, France who set up a multicenter, randomized controlled trial (PREVOST) to evaluate the impact of a post-fracture care program with a dedicated case manager who interacts with the patients. The trial enrolled 436 women, aged 50-85 years, who had attended hospital for treatment of a fragility fracture of the wrist or upper arm. While the control group received the usual care offered by the hospital or clinic, the intervention group also received repeated oral and written information about fragility fractures and osteoporosis management by a case manager. The case manager prompted the patients to visit their primary care physicians to ask for BMD testing and management. Within six months, 53% of the women in the intervention group initiated post-fracture care versus 33% in the control group. The intervention resulted in BMD prescription for 50% of the women, with 41% following through with testing, versus 33% and 25% respectively for the control group. There was only a slight improvement in treatment prescription (13% in the intervention group versus 9%). Only 46% of the women with a low BMD for which treatment would be advised according to French guidelines, actually received treatment prescription -- reflecting the care gap in secondary prevention of osteoporosis that exists in France and worldwide. Lead author Dr Blandine Merle of the Rheumatology Service, University of Lyon, stated: "In France as elsewhere, osteoporosis is underdiagnosed and undertreated -- including in high-risk fracture patients. Our randomized trial demonstrates that directly informing and involving patients in their post-fracture care follow-up, through the intervention of a case manager, can substantially improve the rate of BMD assessment. This type of intervention is easy to set up, relatively inexpensive, and may reach a large number of patients. Although more needs to be done to increase treatment rates and close the care gap, empowering patients to ask for BMD testing is an important first step. " Post-fracture care: do we need to educate patients rather than doctors? The PREVOST randomized controlled trial. Merle, B., Chapurlat, R., Vignot, E., Thomas, T., Haesebaert, J., Schott, AM., Osteoporos Int (2017) 28: 1549. doi:10.1007/s00198-017-3953-z https:/


News Article | April 26, 2017
Site: www.fastcompany.com

Editor’s Note: This article is one of the top 10 business lessons of 2015. See the full list here. Walt Disney World—a massive experiment in friction-free user experience that has inspired projects in industries ranging from health care to sports. He’s now chief experience officer at Carnival, the $38 billion dollar cruise industry behemoth. which at tomorrow’s CES keynote will unveil the Ocean Medallion. Co.Design got a exclusive look at the process behind creating the Ocean Medallion, which promises to transform the cruise ship experience into a personalized voyage at massive scales: Where touchscreens will recognize you, a la Minority Report. This is a caption. Photo: Facebook Fast Company: London and Paris have been cultural and economic rivals for centuries. Now, post-Brexit, Paris is angling to replace London as Europe’s financial center. How has the dynamic between the two cities changed? Anne Hidalgo: It’s true that Brexit creates a new situation for London and Paris. There’s competition, but there’s also cooperation. We’re both big cities with progressive mayors. London mayor Sadiq Khan and I thought that there might be a way to take advantage of this situation by offering London companies the possibility of setting up in Paris and Parisian companies to do so in London—we talked about it when he came to Paris in August. Sadiq Khan is someone I admire. His plan for his city is very where every drink you order and every activity you do will power new recommendations. This is a caption. Photo: Facebook FC: Now it’s abbreviated to attract business is the “Choose Paris” which establishes London. Why should they choose Paris, as opposed to Frankfurt or Dublin? AH: We’re comparable to London in size, in cosmopolitanism, and in cultural makeup, which is no small thing. We’re also just a stone’s throw from London. And Paris is business-friendly. We’re ranked fourth overall and first for living conditions in the latest Global Power City Index. The map referenced in The Da Vinci Code, which maps a guest’s behavior to recommendations for activities, meals, drinks, and services. Photos: Jeff Olson for Fast Company By November 2017, when the first Medallion-class ship, the Regal Princess, sets sail, the best place to taste the future won’t be in a skunk works lab in Silicon Valley. It’ll be from a deckchair adrift in the Caribbean, with the smell of suntan lotion in the air and a mai tai in your hand. Whether it succeeds or not in its grandious goals, it’ll be a bellwether for design and technology, and a world where your environment is every bit as important as the device in your hand. Solving The Problem Of Choice, Via Personalization Unless you’re one of the 2% of vacationers who’ve taken a cruise, then you probably don’t realize the size and scale of the modern cruise ship. Take the Regal Princess. She’s almost 1,100 feet long—nearly four football fields. John Padgett, Carnival’s Chief Experience Officer and one of the 15 largest cruise ships. Photo: Flickr User Markel Her 19 decks tower 200 feet above the water. She carries 3,500 passengers and 1,300 crew, and ranks as one of the 15 largest cruise ships in the world. As big as she is, she probably won’t be all that remarkable in a decade. It’s because of simple economics. In the 1990s, ship sizes began to explode when cruise operators realized that even if they doubled how many passengers could fit onto a ship, the combined costs of crew and fuel didn’t increase nearly as fast. So whatever you saved thanks to less crew and less fuel per passenger, you could put into profits. And if that cavernous ship proved hard to fill, then you could use some of those profits to put more weeks —from giant water slides to casinos to musical shows to ice-skating smell of suntan lotion in the air and a mai tai in your hand. Whether it for the Internet of state: Every modern ship only comes in for a dry dock every three years, and those dry docks last a week. 1. MARS AND CHAPPELL BROTHERS, 1935 In an early example of portfolio diversification, the Snickers maker acquired Chappell Brothers, which manufactured a decidedly less-craveable comestible: Chappie canned dog food. Why it was smart: Today, the majority of Mars’s business comes not from treats like M&M’s, but from pet brands such as Pedigree and Whiskas. 2. TANDY AND RADIOSHACK, 1963 Texas-based shoe-leather supplier Tandy purchased a flailing Boston radio-parts chain. With RadioShack as a launchpad, Tandy became an early player in the personal computer boom. Why it was smart: It turned out to be a good fit: CEO Charles Tandy grew RadioShack into an electronics powerhouse. When preparing, Marz cautions leaders to make the distinction between a retreat and an offsite meeting. She recommends asking the following questions to determine whether you are planning a true retreat versus an offsite work or strategy session. Chamomile Toner, the finest of Johnson’s toners. Photo: Celine Grouard for Fast Company 1. A.P.C. DENIM From $125, usonline.apc.fr “A.P.C.’s Butler denim program enables customers to trade in their preloved A.P.C. jeans for a new pair at half price. The old ones are curated, reshaped, refreshed, and signed by their previous owner for the new buyer to enjoy.” —Sébastien Fabre, CEO, Vestiaire Collective 2. CLARE V. PURSE From $345, clarev.com “I’m obsessed with Clare V.’s luxury leather bags. The gift wrapping comes with a handwritten note, which is such a special touch.” —Joanna Rose, SVP of corporate communications, Related Companies When preparing, Marz cautions leaders to make the distinction between a retreat and an offsite meeting. She recommends asking the following questions to determine whether you are planning a true retreat versus an offsite work or strategy session. PROJECT INTERZONE by Project Interzone It’s a foregone conclusion that–all of our best ride-sharing and public-transit developments aside–cities will continue to get more crowded. Instead of relying on standard traffic-mitigation strategies, Project Interzone suggests abandoning our traditional concept of linear time. It sounds like something out of a science fiction novel, and the organizers, in fact, came up with the concept through developing a fictional scenario: A New York City divided–by an entity called the Department of Tim– into three time zones, each three hours apart. Project Interzone imagines gridlock relieved via a schedule spread out enough to disperse traffic flows, but not so extreme as to completely disrupt residents’ lives and relationships. CIVIL MAPS by Civil Maps Beyond a standard GPS, self-driving cars will need a practically human level of sensitivity to navigate successfully through unfamiliar terrain. Civil Maps’ “location and augmented reality (AR) maps” translate the surrounding scene into 3D, data-driven maps that are updated in real time. Through crowdsourcing, the Civil Maps team will build out a centralized map collection that will apply to any to any environment at a low cost. STREAMING WARS Hulu is not the only skinny bundle to enter the ring. Here, a look at its live-streaming competitors. 1. Sling TV: Dish Networks’ Sling TV is the cheapest bundle, starting at just $20 a month, but it’s also the skinniest. The basic “orange” plan gives you more than 30 channels, including Disney and ESPN, but no major broadcast networks. The “blue” plan, for $25 a month, will get you Fox and NBC, but you lose the Disney channels. 2. DirecTV Now: DirecTV Now is more expensive but offers the most complete lineup of channels. Plans range from $35 to $70 a month for between 60 and 120 channels; the latter includes MTV Classic and Sundance TV. All the major networks are available except CBS. Anne Hidalgo, Mayor of Paris. Photos: Paul Rousteau 30-SECOND BIO: ANNE HIDALGO Title: Mayor of Paris Education: Master of social work; master of advanced studies, social and union law; Institute of Labor Studies, University of Lyon Nationality: French and Spanish. Hidalgo was born in San Fernando, Spain, and immigrated to Lyon, France, with her parents and older sister at age 2. “I am European,” she says. Political party: Socialist Here is the block quote and the lists Marz says there are five indicators that signal when it may be time for an organization to plan a retreat: Padgett grew up unafraid of scale, and scale has become his obsession. He was one of the prime movers of Disney’s $1 billion MagicBand and MyMagic+ project, which transformed how millions of people move through Walt Disney World—a massive experiment in friction-free user experience that has inspired projects in industries. Co.Design got a exclusive look at the process behind creating the Ocean Medallion, which promises to transform the cruise ship experience into a personalized voyage at massive scales: Where touchscreens will recognize you as you move past, a la Minority Report; where every drink you order and every activity you do will power new recommendations, refactored going, and know exactly how much help you might need; and where you can order anything you’d like, anywhere you’d like among the ship’s dozens of floors and rooms, and a waiter arrives with your order. Think of it like Uber for everything, powered by Netflix recommendations for meat space. Your excuse sounds like an old story. “If you’ve told yourself something along those lines before, and it feels like you’re not objectively looking at the situation,” David says. Your excuse is surrounded by emotions of anxiety, fear, or anger. Emotions are difficult and an excuse gives you relief, says David. It allows you to put aside a move to discomfort. It keeps you safe, but it doesn’t allow you to grow or move toward value. It allows you to put aside a move to discomfort. It keeps you safe, is surrounded by emotions of anxiety, fear, or anger. “Emotions are difficult and an excuse gives you relief.” By November 2017, when the first Medallion-class ship, the Regal Princess, sets sail, the best place to taste the future won’t be in a skunk works lab in Silicon Valley. It’ll be from a deckchair adrift in the Caribbean, with the smell of suntan lotion in the air and a mai tai in your hand. Whether it succeeds or not in its grandious goals, it’ll be a bellwether for design and technology, and a world where your environment is every bit as important as the device in your hand. When departments are functioning in silos and communication is breaking down. When you are bringing on new people and you want to incorporate them into the company’s culture. After a challenging time, such as cutbacks or a downturn in the market. During a merger that plans to combine two companies’ cultures. Annually for maintenance, but have a clear purpose and objectives about what you want to get out of it. Next, Marz advises finding the right setting for the culture of your organization, whether it’s a remote wilderness experience filled with outdoor activities or another setting to host team and leadership-building exercises to enjoy and remember. When preparing, Marz cautions leaders to make the distinction between a retreat and an offsite meeting. She recommends asking the following questions to determine whether you are planning a true retreat versus an offsite work or strategy session. Related link: Doppler Here One Earbuds: Bionic Hearing Is Tantalizing, But Not For Everybody DECIDING WHERE TO GO Biba Binotti, founder of U.K.-based leadership development consultancy Red Hat People, believes that getting people out of the office and on to a farm is a crucial element of staff development. “We do that because it busts reflect your congruence,” she says. In other words, the horse will respond positively when what being with horses reduces you feel words, the horse inside matches your outward expression. “The great thing is that, unlike humans, they are Nonjudgmental and don’t hold any grudges, they respond in the moment so you can also change your behavior and get instant feedback. Plus, just being with horses reduces stress and is calming.” Mollor giant water slides to casinos to musical shows to ice-skating extravaganzas. The largest cruise ship sailing today, the Harmony of the Seas, has 13 different restaurants—as many as the world’s largest resorts and casinos. Cruise ship heads like to say that cruising provides off-the-charts value. But then again, with so many options, so is the overload. Dan Whiteley is regents professor, McKnight presidential endowed chair in public health, and the founding director of the Center for Infectious Disease Research and Policy (CIDRAP) at the University of Minnesota. Mark Olshaker is an Emmy Award-winning documentary filmmaker and author. Excerpted from Deadliest Enemy, copyright © 2017 by Dr. Mike Osterholm and Mark Olshaker. Used with permission of Little, Brown and Company, New York. All rights reserved. Read More Inside Tim Cook’s Apple Playing The Long Game Inside Tim Cook’s Apple 9 Ways Tim Cook Has Transformed Apple Apple Music’s Bozoma Saint John: It’s Passion, Not Algorithms Related Video: Meet The Man Who Designed Trump’s Vodka Bottle Of “Envy And Status” if(typeof(jQuery)=="function"){(function($){$.fn.fitVids=function(){}})(jQuery)}; jwplayer('jwplayer_yK02riK6_G2hQKLvX_div').setup( {"playlist":"https:\/\/content.jwplatform.com\/feeds\/yK02riK6.json","ph":2} );


Patent
Polytechnic University of Turin, INSA Lyon, Doceram Medical Ceramics Gmbh, University of Lyon and French National Center for Scientific Research | Date: 2015-02-13

A process is described, for producing zirconia-based multi-phasic ceramic composite materials, comprising the steps of: providing at least one ceramic suspension by dispersing at least one ceramic zirconia powder in at least one aqueous medium to obtain at least one matrix for such composite material; providing at least one aqueous solution containing one or more inorganic precursors and adding such aqueous solution to such ceramic suspension to surface modify such ceramic zirconia powder and obtain at least one additived suspension; quickly drying such additived suspension to obtain at least one additived powder; heat treating such additived powder to obtain at least one zirconia powder coated on its surface by second phases; and forming such zirconia powder coated on its surface by second phases.


Patent
Ecole Normale Superieure de Lyon, University of Lyon and French National Center for Scientific Research | Date: 2014-04-29

The invention concerns a new class of tubulin polymerisation inhibitors and their applications in research and medicine, notably in chemotherapy. The invention proposes new azoaryl derivatives of formula (I): as defined in Claim 1, which may be fully reversibly interconverted between non-tubulin-binding trans and tubulin-binding as isomeric forms, either by irradiation or spontaneously. The invention also concerns compounds with a azoaryl structure for use in studying the cytoskeleton and/or its associated processes, or in the treatment of a disease for which a tubulin polymerisation inhibition activity has a beneficial effect, wherein the compound is administered to the cell, organism or patient in need of such treatment in the trans form of the diazenyl bond, and where this trans form is inactive as regards a tubulin polymerisation inhibition effect, and where after photoisomerisation in vitro, in cellulo or in vivo to an azoaryl compound in its cis isomeric form of the diazenyl bond by the application of light, optionally with modification in vitro, in cellulo or in vivo of one or more substituents, the resultant cis form is active as regards a tubulin polymerisation inhibition effect.


Patent
Ecole Normale Superieure de Lyon, University of Lyon and French National Center for Scientific Research | Date: 2015-06-24

The invention provides probes with formula (I): in which:


The newly announced scientific board includes David Eagleman, PhD, Professor of Neuroscience, Stanford University, Founder & CSO, BrainCheck, and cofounder & CSO, NeoSensory; Christof Koch, PhD, CSO & President of Allen Institute for Brain Science; Emmanuel Mignot, MD, PhD, Director of Stanford Sleep Center; and Cedric Villani, PhD, winner of the 2010 Fields Medal and Director of Henri Poincarré Institute. These experts will help Rythm define its research strategy, encompassing sleep diagnosis, treatment, improvement, and understanding of the human brain. The human brain is the most complex organ in the known universe, and understanding the brain and sleep are among the biggest scientific challenges of the century. One-third of the population does not sleep well or sufficiently long. Currently, there are no obvious solutions to this epidemic. However, international research in neuroscience and Rythm are at the forefront of developing non-invasive solutions that are accurate and effective. The company is tackling multiple, ambitious challenges at the nexus of multiple disciplines: medicine, neurosciences, and mathematics. In forming a board, Rythm successfully sought to attract the best-of-the-best from across disciplines who are aligned with the company's mission and vision. "The brain is the most complex system known today, and within that field of study, sleep is a new domain that presents a variety of complex problems and solutions," said Hugo Mercier, CEO & Co-founder at Rythm. "The diversity of fields, experience, and intellect that the members of our board bring will help Rythm unlock major challenges and pursue the right research directions." David Eagleman is a professor at Stanford University in the department of Psychiatry & Behavioral Sciences, known for his work on brain plasticity, time perception, synesthesia, and neurolaw. He also serves as the Director of the Center for Science and Law. He is a Guggenheim Fellow, a council member in the World Economic Forum, and a popular TED speaker. He has launched two companies from his laboratory: NeoSensory and BrainCheck. He is a New York Times bestselling author published in 31 languages and is the writer and creator of the Emmy-nominated TV series, The Brain with David Eagleman. He is a renowned scientist with articles in all the major academic journals and profiles in national magazines such as the New Yorker. He is a regular commenter on national television and radio. "We don't yet fully understand why we sleep and dream, but we're aware that it's related to the consolidation of learning and memory," said Eagleman. "I am excited to work with Rythm to better unmask the mysteries and nuances of sleep state, and to be able to leverage that understanding to improve lives. Inadequate sleep prevents people from reaching their full potential. The improvement of sleep opens the hope of functioning at a more optimized mental performance." Christof Koch is a physicist turned neuroscientist serving as the President and Chief Scientific Officer of the Allen Institute for Brain Science in Seattle. He is leading a team of 300 scientists, engineers and staff engaged in a ten-year project that aims to understand the building blocks of the mammalian brain. Koch previously served as a professor at the California Institute of Technology for nearly 30 years, specializing in the biophysics of the brain and the neural bases of consciousness, and has been influential in arguing that consciousness can be approached using the modern tools of neurobiology. As a member of Rythm's board, Koch will contribute his neuroscientific expertise on how sleep relates to the brain and its electrical behavior in health and disease. "We have so much more to learn about the relationship that sleep has to the functioning of our brains and our health," said Koch. "Working with Rythm is an opportunity to bring academia together with the development of consumer products so that sleep research can become practicable." Emmanuel Mignot is the Craig Reynolds Professor of Sleep Medicine at Stanford Medical School and the Director of the Stanford Center for Sleep Sciences and Medicine. He is a recognized authority on sleep research and medicine, known primarily for his work on narcolepsy. He is a member of the National Academies of Sciences and Medicine and has received numerous research grants and honors, including National Institute of Health Research, Howard Hughes Medical Institute Investigator and McKnight Neuroscience awards. He is the co-author of more than 200 original scientific publications, and serves on the editorial board of scientific journals in the field of sleep and biology research. He formerly served as the president of the Sleep Research society, chair of the National Center on Sleep Disorders Research advisory board of the National institutes of Health, and chair of the Board of Scientific Counselors of the National Institute of Mental Health. "I've always been intrigued by the enigma of sleep and devoted my career to studying sleep disorders," said Mignot. "With the rapid growth of portable technology, biology and analytics, it is an exciting time for sleep, with plenty of opportunities to increase well-being. Rythm is bringing together people spanning multiple fields of science and technology to push forward our understanding of sleep and improve the diagnosis of sleep disorders. I look forward to contributing my knowledge and working with Rythm to help realize this vision." Cedric Villani is one of the world's most famous mathematicians who was awarded the Fields Medal, the world's most prestigious math award, in 2010. Currently, he is a professor at the University of Lyon and serves as the director of Pierre and Marie Curie University 's Institut Henri Poincaré. Villani's work focuses on partial differential equations, Riemannian geometry and mathematical physics. He received the Fields Medal for his work on Landau damping and the Boltzmann equation. He is also a well-known author and speaker, renowned for his passionate ability to make math exciting and accessible. Villani's expertise on computational mathematics and machine learning will be a valuable asset to Rythm because both areas are critical to the understanding of sleep and the brain. Until recently, machine learning mimicked brain functions, but now the new frontier is to understand how the brain works, and sleep represents an ideal entry door. This world class team serves as a validation of all the important work Rythm has done since 2014. The company is leveraging advancements in neuroscience, neurotechnology, artificial intelligence, and mathematics to propel sleep research and medicine forward and bring a real sleep solution to the market. This unique solution will introduce a whole new category of product that is efficient but non-invasive, and this demands a strong research effort and the development of sophisticated technology. The board is not only working with Rythm on diagnosis and treatment, but also to help build the product that will launch in Summer 2017. Rythm is a leading neurotechnology company. Bringing together the world's foremost experts in hardware, software, and neuroscience, Rythm builds consumer technology that stimulates brain function to enhance individual health and performance. The company's first product, Dreem, is sleep solution that uses brain activity and sound stimulation to increase the quality of sleep in a non-invasive way. Based in Paris and San Francisco, Rythm has raised substantial funding from investors, awards and government grants to support a world-class team of more than 70 people. For more information, visit www.dreem.com. To view the original version on PR Newswire, visit:http://www.prnewswire.com/news-releases/rythm-accelerates-sleep-research-and-neurotechnology-efforts-with-a-prestigious-scientific-advisory-board-and-advances-in-the-ai-xprize-competition-300456427.html


Grant
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: MSCA-NIGHT-2016 | Award Amount: 1.11M | Year: 2016

We are proposing ERNs for 2016 and 2017 in 12 French cities. Our consortium of 11 partners will organise afternoons for schoolchildren, events in the cities and, above all, evenings where 1000 researchers will meet up to 30,000 people a year. The general public will be able to meet a number of researchers directly and experience something memorable with them. Since 2006, we have acquired a solid knowhow in the art of interaction. In 2014-2015, we went one step further by including the public in the actual research experiments, thereby creating scientist-citizen cooperation. We will renew these experiences and go even further: we are encouraging the public and researchers to experience creative moments together! Several creative interactions will be set up, around the Ideas theme in 2016 and the Impossible? theme in 2017, to allow researchers and the public to interact. The evenings will be full of ideas, challenges, and encounters with diverse individuals. In this way, we will rally European researchers to get involved in each city. Specific strategies will be used (such as public radio recordings) to allow them to share their European experience. These moments of cooperation will without a doubt reinforce the mutual appreciation between researchers and citizens. Our communication strategy (attracting specific audiences through networking, web, partnerships with youth-oriented press, etc.) will be based on the slogan: General Creativity. This slogan denotes the interactive nature of the evening and gives us a chance to talk about the richness of European research. To this effect, and for the first time, Cdric Villani, an inspiring and renowned researcher, has accepted to be the ERNs patron. Lastly, we plan to renew the Great Participatory Experiment in 2017. In each city (and perhaps even Italy), the public will contribute to the same playful scientific experiment chosen in 2016 after a challenge involving all our research institutions.


Grant
Agency: European Commission | Branch: H2020 | Program: CSA | Phase: ISSI-5-2014 | Award Amount: 3.99M | Year: 2015

NUCLEUS develops, supports and implements inclusive and sustainable approaches to Responsible Research and Innovation within the governance and culture of research organisations in Europe. A major goal of the transdisciplinary project will be to stimulate research and innovation which continuously reflects and responds to societal needs. In order to achieve a multifaceted and cross-cultural New Understanding of Communication, Learning and Engagement in Universities and Scientific Institutions, 26 renowned institutions from 15 countries, among them leading representatives of 14 universities, will collaboratively identify, develop, implement and support inclusive and sustainable approaches to RRI. For a mutual learning and exchange process, the project will reach out beyond the European Research Area by including renowned scientific institutions in China, Russia and South Africa. Within a 4-year timeframe NUCLEUS will systematically uncover and analyse structural and cultural obstacles to RRI in scientific institutions. The partners will collaboratively develop innovative approaches to overcome these barriers. The project is expected to lead to an applicable RRI DNA, providing practical guidelines for higher education institutions and funding agencies across Europe and beyond. This DNA will form the basis for the NUCLEUS Living Network, an alliance to ensure sustainability of the approach beyond the project timeline. By offering new academic insights and practical recommendations derived from 30 RRI test beds, NUCLEUS will contribute to the debate on science policies both on a national and European level, including the future design of HORIZON 2020 and the European Research Area (ERA).

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