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Louisville, KY, United States

The University of Louisville is a public university in Louisville, Kentucky, a member of the Kentucky state university system. When founded in 1798, it was the first city-owned public university in the United States and one of the first universities chartered west of the Allegheny Mountains. The university is mandated by the Kentucky General Assembly to be a "Preeminent Metropolitan Research University". U of L enrolls students from 118 of 120 Kentucky counties, all 50 U.S. states, and 116 countries around the world.Researchers from the University of Louisville Health science Center participated in the development of a highly effective vaccine against cervical cancer in 2006, the first fully self-contained artificial heart transplant surgery, the first successful hand transplantation, and the development of the Pap smear test. The University Hospital is also credited with the first civilian ambulance, the nation's first accident services, now known as an emergency room , and one of the first blood banks in the US.Between 1999 and 2006 U of L was one of the fastest growing medical research institutions according to National Institutes of Health rankings. As of 2006, the melanoma clinic ranked third in among public universities in NIH funding, the neurology research program fourth, and the spinal cord research program 10th.U of L is also known for its athletics programs, several of which are among the most successful in the country. Since 2005 the Cardinals have made appearances in the men's basketball Final Four in 2005, 2012, and 2013 , football Bowl Championship Series Orange Bowl in 2007 and Sugar Bowl in 2013 , the College Baseball World Series 2007, 2013, and 2014, the women's basketball Final Four in 2009 and 2013 , and the men's soccer national championship game in 2010. U of L's women's volleyball program has three-peated as champions of the Big East Tournament , and its women's track and field program has won Outdoor Big East titles in 2008, 2009 and 2010 and an Indoor Big East title in 2011. Wikipedia.

A composition is provided that includes a microvesicle derived from an edible plant and a therapeutic agent conjugated to the microvesicle. The therapeutic agent can be chemically-linked to a plasma membrane of the microvesicle with a cross-linking agent and the edible plant can be a fruit or a vegetable. Methods for treating an inflammatory disorder or a cancer are further provided and include administering to a subject in need thereof an effective amount of a composition including a microvesicle derived from an edible plant and having a therapeutic agent conjugated to the microvesicle.

University of Louisville | Date: 2015-05-27

Present embodiments provide an energy-efficient separator having at least two chambers fluidically isolated by a gas permeable membrane for the removal of dissolved gases from a sample which, in some aspects, enables cost-effective monitoring of liquid samples to be performed remotely and automatically, and in other aspects is suited for various other applications where removal and/or regulation of gases in a sample are desirable.

University of Louisville | Date: 2015-11-19

A composition is provided that includes an anti-CD19 single chain variable fragment (scFv) conjugated to a tumor-associated antigen. The antigen can comprise a Her-2/neu protein, such as a Her-2/neu extracellular domain. Methods of eliciting an immune response are also provided along with methods of treating, or limiting the occurrence of, cancer in a subject.

A catalytic process is provided which produces in a single reaction branched, cyclic and aromatic hydrocarbons, or cracked straight-chain hydrocarbons, from fatty acids in which the fatty acids are reacted over a multifunctional catalyst and undergo both decarboxylation and further conversion(isomerization, cyclization, aromatization, or cracking) to form reaction products useful as fuels and for other applications that require a source of energy, or as feedstock for hydrocarbon-based commercial products such as surfactants, solvents and lubricants.

University of Louisville | Date: 2015-11-13

Embodiments disclosed herein relate to a method for synthesizing self-assembling nanoparticles with defined plasmon resonances. More particularly, certain embodiments disclosed herein relate to an improved method for synthesizing self-assembling gold nanoparticles by dialyzing samples during the self-assembly process or in presence of a surface to reduce certain subpopulations.

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