Liverpool, United Kingdom

University of Liverpool

www.liverpool.ac.uk
Liverpool, United Kingdom

The University of Liverpool is a public university based in the city of Liverpool, England. Founded in 1881 as a university college, it is also one of the six original "red brick" civic universities. It comprises three faculties organised into 35 departments and schools.It is a founding member of the Russell Group of research-intensive universities, the N8 Group for research collaboration and the University Management school is AACSB accredited.The university has produced nine Nobel Prize winners and offers more than 230 first degree courses across 103 subjects. It was the world's first university to establish departments in Oceanography, civic design, architecture, and biochemistry at the Johnston Laboratories.In 2006 the university became the first in the UK to establish an independent university in China making it the world's first Sino-British university.It has an annual turnover of £410 million, including £150 million for research.Graduates of the University are styled with the post-nominal letters Lpool, to indicate the institution. Wikipedia.

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Patent
University of Washington and University of Liverpool | Date: 2016-10-21

Compounds are disclosed that inhibit the methylerythritol cytidyltransferase (IspD) enzyme in the non-mevalonate pathway (MEP pathway), which is present in many organisms including the P. falciparum parasite. Inhibitors of the IspD enzyme in the non-mevalonate pathway of the P. falciparum parasite are useful for treating malaria.


Patent
University of Liverpool | Date: 2017-05-31

Particles comprising a branched polymer and either a block copolymer or a linear dendritic hybrid represent a category of useful materials. They may be used in for example drug delivery applications. They may be prepared by a method comprising the steps of: dissolving the branched polymer and block copolymer or linear dendritic hybrid, and optionally other component(s),in a solvent to form a solution; adding said solution to a different liquid; and removing said solvent to form a dispersion of co-precipitated particles.


Patent
University of Liverpool | Date: 2015-07-17

Particles comprising a branched polymer and either a block copolymer or a linear dendritic hybrid represent a category of useful materials. They may be used in for example drug delivery applications. They may be prepared by a method comprising the steps of: dissolving the branched polymer and block copolymer or linear dendritic hybrid, and optionally other component(s), in a solvent to form a solution; adding said solution to a different liquid; and removing said solvent to form a dispersion of co-precipitated particles.


Patent
University of Liverpool | Date: 2017-01-18

A device (310) for applying a compressive force to the uterus, the device comprising a contact portion (312) for contacting the uterus and providing a compressive force thereto, and at least two elongate handles (314a, 314b) each extending from the contact portion along a respective longitudinal axis (100a, 100b). The at least two elongate handles are configured to facilitate insertion of the device into the body and handling of the device from outside the body when inserted. At least a part of the contact portion is configured to be radially moveable relative to the longitudinal axes between a first radial position and a second radial position where the second radial position is radially outward of the first radial position.


Patent
University of Liverpool | Date: 2017-02-01

The present invention relates to a process for preparing substituted piperidine compounds and especially chiral substituted piperidine compounds. The process involves reacting a substituted pyridinium ion with an amine as defined herein, in the presence of a hydrogen donor, a catalysts and a suitable solvent.


Patent
University of Liverpool | Date: 2015-04-15

Provided are fusion proteins, polynucleotides and expression vectors with therapeutic utility in the prevention and/or treatment of cancer, as well as medical uses of these agents, and methods of treatment in which they are used. A fusion protein of the invention comprises an amino acid sequence that provides the apoptosis-inducing activity of TRAIL, and a membrane-anchoring amino acid sequence. The amino acid sequence that provides the apoptosis-inducing activity of TRAIL comprises the extracellular domain of TRAIL, or a fragment or variant thereof. A fusion protein comprising an amino acid sequence from TRAIL that is able to induce apoptosis, and a second sequence that anchors the first sequence to the cell membrane, is markedly more effective at reducing viability of TRAIL receptor positive cells than the naturally occurring (wild type) TRAIL protein itself.


Patent
University of Liverpool | Date: 2015-03-12

A device for applying a compressive force to the uterus, the device comprising a contact portion for contacting the uterus and providing a compressive force thereto, and at least two elongate handles each extending from the contact portion along a respective longitudinal axis. The at least two elongate handles are configured to facilitate insertion of the device into the body and handling of the device from outside the body when inserted. At least a part of the contact portion is configured to be radially moveable relative to the longitudinal axes between a first radial position and a second radial position where the second radial position is radially outward of the first radial position.


Patent
University of Liverpool | Date: 2015-06-26

A host material may be used for the separation of elements or compounds, wherein the host material is an organic molecular solid with suitable cavities for accommodating a guest material to be separated, and with interconnections between the cavities to allow the guest material to diffuse through the host material, and wherein said interconnections are closed for a proportion of the time or have a static pore limiting diameter which is smaller than the static dimension of the guest material. Applications include separations of rare gases, chiral molecules, and alkanes. One class of suitable host materials may be made by imine condensation.


Patent
University of Liverpool | Date: 2015-03-24

The present invention relates to a process for preparing substituted piperidine compounds and especially chiral substituted piperidine compounds. The process involves reacting a substituted pyridinium ion with an amine as defined herein, in the presence of a hydrogen donor, a catalysts and a suitable solvent.


De Magalhaes J.P.,University of Liverpool
Nature Reviews Cancer | Year: 2013

The ageing of populations worldwide is leading to an unprecedented increase in cancer cases and fatalities. Understanding the links between cancer and ageing is therefore more important than ever. How the interplay of ageing-associated changes affects cancer initiation and progression is complex, however, and some ageing processes probably foster cancer development whereas others hinder it, possibly in a tissue-specific manner. In the emerging age of cancer, how can our growing understanding of the biology of ageing inform cancer biology? © 2013 Macmillan Publishers Limited. All rights reserved.

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