Leeds, United Kingdom
Leeds, United Kingdom

The University of Leeds is a British Redbrick university located in the city of Leeds, West Yorkshire, England. Wikipedia.


Time filter

Source Type

Patent
Mayo Foundation For Medical Education And Research and University of Leeds | Date: 2015-03-19

This document provides methods and materials for treating cancer. For example, methods and materials for treating cancer using combinations of antigens are provided. For example, VSV vectors designed to express a GNAQ antigen, a TYRP1 antigen, and an N-RAS antigen can be used to reduce the number of cancer cells (e.g., uveal melanoma cells) within a mammal (e.g., a human). In some cases, VSV vectors designed to express a BRAF antigen, a TOPO-lla antigen, and a YB-I antigen can be used to reduce the number of cancer cells (e.g., skin melanoma cells) within a mammal (e.g., a human). The composition can comprise less than 50 separate nucleic acid molecules.


Patent
University of Leeds | Date: 2017-01-04

The present invention is concerned with a dye system for application to a substrate, the dye system comprising: (a) at least one dye precursor; (b) an oxidising agent; and (c) a catalyst, wherein the catalyst is a homogenous catalyst or a heterogeneous catalyst. Preferably, the catalyst comprises at least one metal-containing compound. The invention also envisages a method for the coloration of a substrate, the method comprising treating the substrate with the dye system of the invention. In preferred embodiments of the invention, the substrate comprises human hair, natural or synthetic polymers, or textile fibres. In further preferred embodiments, the at least one dye precursor is an organic precursor, the at least one metal derivative for use as a catalyst comprises at least one inorganic metal compound or at least one metal complex comprising at least one organic ligand, and the oxidising agent is hydrogen peroxide.


Patent
Mayo Foundation For Medical Education And Research and University of Leeds | Date: 2017-01-25

This document provides methods and materials for treating cancer. For example, methods and materials for identifying antigens and combinations of antigens that can be used to treat cancer as well as combinations of antigens having the ability to reduce established tumors (e.g., gliomas) within a mammal (e.g., a human) are provided. In general, one aspect of this document features a composition comprising, or consisting essentially of, nucleic acid encoding HIF-2a, SOX-10, C-MYC, and TYRP-1, wherein the composition comprises less than 100 separate nucleic acid molecules.


Patent
University of Leeds | Date: 2015-05-19

A method of controlling a datacentre (1), for example a cloud datacentre, and a computer management system (3) for managing a datacentre comprising a plurality of servers (2) configured to execute a plurality of jobs is provided. The method comprises receiving a request to execute a job from a user (4), determining an allocated server (2) on which to execute the job, and executing the job on the allocated server (2). The determining the allocated server (2) on which to execute the job comprises: classifying the job according to its resource requirement, selecting a subset of the servers (2) that fulfil the resource requirements of the job, determining the allocated server (2) that can execute the job with a favourable energy efficiency, wherein a total resource estimate for all jobs running on the server (2) from time to time exceeds the resources of at least one of the servers (2). Accordingly, the datacentre (1) may over allocate the capacity of the physical servers (2), to overcome the overestimation of required resources by users (4).


Patent
University of Leeds | Date: 2017-03-29

A method of controlling a datacentre (1), for example a cloud datacentre,and a computer management system (3) for managing a datacentre comprising a plurality of servers (2) configured to execute a plurality of jobs is provided. The method comprises receiving a request to execute a job from a user (4), determining an allocated server (2) on which to execute the job, and executing the job on the allocated server (2). The determining the allocated server (2) on which to execute the job comprises: classifying the job according to its resource requirement, selecting a subset of the servers (2) that fulfil the resource requirements of the job, determining the allocated server (2) that can execute the job with a favourable energy efficiency, wherein a total resource estimate for all jobs running on the server (2) from time to time exceeds the resources of at least one of the servers (2). Accordingly, the datacentre (1) may over allocate the capacity of the physical servers (2), to overcome the overestimation of required resources by users (4).


Patent
University of Leeds | Date: 2017-03-15

A dental model scanner comprising a plurality of cameras set apart from one another, a model holder and a light source. The light source projects a sine wave pattern directed onto the surface of the dental model and the relative phase of at least one pixel can be recorded by the plurality of cameras. A method of scanning and creating an occlusion view from upper and lower models with help of makers on the upper and lower jaw.


Patent
Mayo Foundation For Medical Education And Research and University of Leeds | Date: 2016-11-22

This document provides methods and materials for treating cancer. For example, methods and materials for identifying antigens and combinations of antigens that can be used to treat cancer as well as combinations of antigens having the ability to reduce established tumors within a mammal (e.g., a human) are provided.


Patent
University of Leeds | Date: 2017-02-22

There is described variegin for use as a medicament in the treatment of disease or condition characterised in that the variegin is administered in an amount of at least about 0.1 mg/kg (mass of drug compared to mass of patient).


This tutorial review discusses the structural and electronic consequences of the Jahn-Teller effect in transition metal complexes, focussing on copper(ii) compounds which tend to be the most studied. The nature of a Jahn-Teller distortion in molecular complexes and extended lattices can be manipulated by application of pressure or temperature, by doping a molecule into a host lattice, or simply by molecular design. Many of these results have been achieved using compounds with a trans-[CuX4Y2] coordination sphere, which seems to afford copper centres that are particularly sensitive to their environment. Jahn-Teller distortions lead to some unusual phenomena in molecular magnetism, and are important to the functionality of important classes of conducting and superconducting ceramics. © 2013 The Royal Society of Chemistry.


Halcrow M.A.,University of Leeds
Chemical Society Reviews | Year: 2011

Spin-crossover compounds are becoming increasingly popular for device and sensor applications, and in soft materials, that make use of their switchable colour, paramagnetism and conductivity. The de novo design of new solid spin-crossover compounds with pre-defined switching properties is desirable for application purposes. This challenging problem of crystal engineering requires an understanding of how the temperature and cooperativity of a spin-transition are influenced by the structure of the bulk material. Towards that end, this critical review presents a survey of molecular spin-crossover compounds with good availability of crystallographic data. A picture is emerging that changes in molecular shape between the high- and low-spin states, and the ability of a lattice to accommodate such changes, can play an important role in determining the existence and the cooperativity of a thermal spin-transition in the solid state (198 references). © 2011 The Royal Society of Chemistry.

Loading University of Leeds collaborators
Loading University of Leeds collaborators