Leeds, United Kingdom

University of Leeds

www.leeds.ac.uk
Leeds, United Kingdom

The University of Leeds is a British Redbrick university located in the city of Leeds, West Yorkshire, England. Wikipedia.

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Patent
University of Leeds | Date: 2017-02-22

There is described variegin for use as a medicament in the treatment of disease or condition characterised in that the variegin is administered in an amount of at least about 0.1 mg/kg (mass of drug compared to mass of patient).


Patent
University of Leeds | Date: 2017-03-29

A method of controlling a datacentre (1), for example a cloud datacentre,and a computer management system (3) for managing a datacentre comprising a plurality of servers (2) configured to execute a plurality of jobs is provided. The method comprises receiving a request to execute a job from a user (4), determining an allocated server (2) on which to execute the job, and executing the job on the allocated server (2). The determining the allocated server (2) on which to execute the job comprises: classifying the job according to its resource requirement, selecting a subset of the servers (2) that fulfil the resource requirements of the job, determining the allocated server (2) that can execute the job with a favourable energy efficiency, wherein a total resource estimate for all jobs running on the server (2) from time to time exceeds the resources of at least one of the servers (2). Accordingly, the datacentre (1) may over allocate the capacity of the physical servers (2), to overcome the overestimation of required resources by users (4).


Patent
University of Leeds and University of St. Andrews | Date: 2017-08-02

The present invention relates to a hydrogel formulation in which the solid phase is composed of a continuous network of siloxane bonds and one or more calcium phosphate phases doped with one or more metal dopants.


Patent
University of Leeds | Date: 2017-07-12

This present invention provides an orthopaedic medical device, in particular an arthroscopic aid, for stimulating the release of cells and/or encouraging migration of cells to a surgical siteor an injury site. The invention includes, methods of increasing a cell population at a surgical siteor injury, a method of improving surgical outcome of synovial joint procedures and methods of delivering intra-operative minimally manipulated cells to a synovial joint.


Patent
University of Leeds | Date: 2017-07-26

Tomography apparatus comprises: a plurality of electrodes arranged around a perimeter of a cross section of a sample volume for containing a liquid or mixed-phase sample, each electrode being arranged to be in electrical contact with a sample contained in the sample volume; measurement means adapted to perform a set of measurements, each measurement comprising driving a current between a first respective adjacent pair of said electrodes and measuring a voltage developed across a second respective adjacent pair of said electrodes; and processing means adapted to generate a tomogram indicative of sample conductivity over said cross section from said set of measurements. The processing means is arranged to calculate sample conductivity values of a portion of said cross section from said set of measurements and generate said tomogram from said calculated sample conductivity values of said portion using an assumption of symmetry.


A flow monitoring system is described for monitoring flow of a mixed-phase sample comprising at least a first phase and a second phase having different electrical conductivities, the second phase being a liquid or a gas and substantially electrically non- conductive and the first phase being a liquid and having a conductivity higher than the second phase. The system comprises: a conduit through which the mixed-phase sample can be arranged to flow; tomography apparatus arranged to generate tomography data indicative of at least a first conductivity profile of at least a portion of a first cross section of the mixed phase sample when flowing through the conduit; a flow meter arranged to detect flow of the first phase though the conduit and provide a flow signal indicative of a flow velocity of the first phase; and processing means adapted to calculate, from said data, a fraction of said first cross section occupied by the first phase, and calculate, from said fraction and said flow signal, a volumetric flow rate of the first phase through the conduit.


Patent
University of Leeds | Date: 2017-01-04

The present invention is concerned with a dye system for application to a substrate, the dye system comprising: (a) at least one dye precursor; (b) an oxidising agent; and (c) a catalyst, wherein the catalyst is a homogenous catalyst or a heterogeneous catalyst. Preferably, the catalyst comprises at least one metal-containing compound. The invention also envisages a method for the coloration of a substrate, the method comprising treating the substrate with the dye system of the invention. In preferred embodiments of the invention, the substrate comprises human hair, natural or synthetic polymers, or textile fibres. In further preferred embodiments, the at least one dye precursor is an organic precursor, the at least one metal derivative for use as a catalyst comprises at least one inorganic metal compound or at least one metal complex comprising at least one organic ligand, and the oxidising agent is hydrogen peroxide.


Patent
Mayo Foundation For Medical Education And Research and University of Leeds | Date: 2017-01-25

This document provides methods and materials for treating cancer. For example, methods and materials for treating cancer using combinations of antigens are provided. For example, VSV vectors designed to express a GNAQ antigen, a TYRP1 antigen, and an N-RAS antigen can be used to reduce the number of cancer cells (e.g., uveal melanoma cells) within a mammal (e.g., a human). In some cases, VSV vectors designed to express a BRAF antigen, a TOPO-lla antigen, and a YB-I antigen can be used to reduce the number of cancer cells (e.g., skin melanoma cells) within a mammal (e.g., a human). The composition can comprise less than 50 separate nucleic acid molecules.


Patent
University of Leeds and Xiros Ltd | Date: 2017-05-03

There is disclosed a method of forming a tissue engineered construct, a bioreactor for forming a tissue engineered construct, and a tissue engineered construct itself. A disclosed method of forming an implantable tissue engineered construct comprises the steps of: seeding a scaffold with cells to form a tissue construct; locating the tissue construct in a space defined by a tissue construct support element; locating the tissue construct support element within a bioreactor; and operating a load applicator of the bioreactor to apply a cyclical compressive mechanical load to the tissue construct, to stimulate the deposition of tissue matrix in the tissue construct; in which the tissue construct, the tissue construct support element and the load applicator are arranged so that the load applicator can at least initially contact both the tissue construct and the tissue construct support element, so that at least part of a total load generated by the load applicator is borne by the tissue construct support element.


Patent
Mayo Foundation For Medical Education And Research and University of Leeds | Date: 2017-01-25

This document provides methods and materials for treating cancer. For example, methods and materials for identifying antigens and combinations of antigens that can be used to treat cancer as well as combinations of antigens having the ability to reduce established tumors (e.g., gliomas) within a mammal (e.g., a human) are provided. In general, one aspect of this document features a composition comprising, or consisting essentially of, nucleic acid encoding HIF-2a, SOX-10, C-MYC, and TYRP-1, wherein the composition comprises less than 100 separate nucleic acid molecules.

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