Jos, Nigeria
Jos, Nigeria

The University of Jos , abbreviated as Unijos, is a federal university in Jos, Plateau State, central Nigeria. The school offers courses in law, medicine, pharmacy, natural science, social science, the built environment as well as arts and humanities.What became University of Jos was first established in November 1971 as a satellite campus of the University of Ibadan. The first students were admitted in January 1972 as pre-degree students with the first Bachelor of Arts degree program begun in October 1973. In October 1975, then military government under General Murtala Mohammed, established the Unijos as a separate institution. The first Vice-Chancellor of the Unijos was Professor Gilbert Onuaguluchi. Classes began at the newly reorganized University of Jos in October 1976 with 575 students spread over the existing four faculties of Arts and Social science, Education, Natural science and Medical science. Post-graduate programs were added in 1977. By 1978 Faculties of Law and Environmental science were established and the Faculties of Arts and Social science were separated.In 2003, the Carnegie Corporation of New York gave Unijos a US $2 million grant to form its own fundraising department. Wikipedia.

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Agency: European Commission | Branch: FP7 | Program: CP-FP-SICA | Phase: HEALTH.2010.2.4.1-4 | Award Amount: 4.78M | Year: 2011

Chronic hepatitis B virus (HBV) infection affects 350 million people worldwide and 25-30% of these individuals will die as a result of their infection mainly as a results of hepatocellular carcinoma HCC. Liver cirrhosis, high viral load and dietary exposure to aflatoxin are recognised as risk factors for hepatocellular carcinoma amongst HBV carriers. However, these variables do not account for all cases of HCC and decompensated cirrhosis is rarely ever seen in West Africa suggesting that advanced liver fibrosis may not be an important risk factor in this population. A large case control study on HCC will be used to evaluate the importance of liver fibrosis and other established risk factors in West Africa and to explore other potential oncogenic determinants. The case-control study will generate serum, urine and DNA samples for proteomic, metabonomic and genomic analysis to identify biomarkers and aetiological agents for HCC. Effective treatment for HBV infection is now available in the developed world but treatment programmes have not been developed for resource poor settings even though some of the effective medication is now available at low cost for HIV management. A trial of HBV treatment in a group of carefully selected high risk patients will be conducted to demonstrate that the incidence of HCC can be reduced in this population as has been observed in Asian patients. The treatment trial will also be used to evaluate the efficacy of screening by ultrasound for early tumours which can be treated with percutaneous alcohol injection. This comprehensive programme therefore aims to reveal novel aetiological factors for HCC, identify and evaluate biomarkers and demonstrate the efficacy of selective antiviral therapy to prevent HCC

Anzaku A.S.,Bingham University | Musa J.,University of Jos
Archives of Gynecology and Obstetrics | Year: 2013

Objective: The study aimed at determining the prevalence and associated risk factors for gestational diabetes mellitus (GDM) among antenatal women attending the Jos University Teaching Hospital (JUTH), Jos, Nigeria. Methods: A cross-sectional study was done between February and April 2009 among 265 pregnant women enrolled from the antenatal clinic of JUTH. Screening was done between 24 and 28 weeks' gestation with a 50 g, 1-h glucose challenge test (GCT). Those with plasma glucose concentration >7.8 mmol/l were then given 75 g oral glucose tolerance test (OGTT) to confirm the diagnosis of GDM. Plasma glucose measurements were performed with glucose oxidase method. GDM was diagnosed according to the WHO criteria. All relevant data including demographic information, obstetric history, and risk factors for GDM, GCT and OGTT results were collected and analyzed using Epi Info version 3.5.1, CDC, Atlanta, USA. Results: Of the 265 pregnant women enrolled, 253 subjects were eligible for screening out of which, 28 (11.1 %) had positive GCT >7.8 mmol/l. The prevalence of GDM was 8.3 % (21/253); 95 % CI 5.2-12.4. The pattern of glucose tolerance in the study population indicated that 232 (91.7 %) had normal glucose tolerance, 6.7 % had impaired glucose tolerance (IGT) while 1.6 % had overt diabetes. Previous history of fetal macrosomia was independently associated with GDM (adjusted OR 11.1; 95 % CI 2.93-42.12, P = 0.0004). Conclusion: The prevalence of GDM was relatively high among our antenatal population. Women with previous history of fetal macrosomia have a higher likelihood of having GDM and should be screened. © 2012 Springer-Verlag Berlin Heidelberg.

Apetrei C.,University of Jos | Rodriguez-Mendez M.L.,University of Valladolid | De Saja J.A.,University of Valladolid
Electrochimica Acta | Year: 2011

An amperometric biosensor was constructed by immobilization of enzyme, tyrosinase, in an electrochemically synthesized phosphate ion-doped polypyrrole film on a Pt disk electrode. The tyrosinase maintains its bioactivity well within the polypyrrole thin film. A clearly defined reduction current proportional to the phenolic compounds concentration was observed in cyclic voltammetry, which attributed to the reduction of enzymatically produced quinone at the electrode surface. Phenolic compounds were quantitatively estimated in aqueous medium by the direct electrochemical reduction of enzymatically liberated quinone species at -0.05 V by chronoamperometry. For the all six phenolic compounds analyzed, the kinetics of the enzymatic reaction fitted into a Michaelis-Menten type kinetics, as demonstrated by the h parameter close to 1 obtained from the Hill's plot. The sensitivity followed the decreasing order catechol > phenol > 2-bromophenol > 2-chlorophenol > 2-iodophenol > 2-fluorophenol. The greater value of Imax and the lowest KMapp was found for catechol. The detection limits were in the range of 0.84-8.54 μM. The lowest detection limits were found for catechol and the highest for 2-fluorophenol. © 2011 Elsevier Ltd.

Damulak O.D.,University of Jos
Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria | Year: 2013

Syphilis is one of the mandatory transfusion transmissible infections to be tested for in any unit of blood for homologous transfusion. The paucity of voluntary blood donors in Nigeria has compelled health care providers to rely on paid and family replacement donors for blood. This study was carried out to determine the prevalence of syphilis among blood donors at a centralized Transfusion Service in North Central Nigeria. Records of blood donors at the North Central Zonal Centre of the National Blood Transfusion Service in Jos, from April 2007 to March 2010 were analyzed for sero-positivity to Treponema pallidum and co-infections with other transfusion transmissible infections. 9,500 blood donors where received at the Transfusion Service Centre in Jos within the study period. The overall prevalence of syphilis among blood donors was 0.9%. New voluntary non remunerated donors constituted 69.9% with a syphilis sero-positivity of 0.9% and 0.2% co-infection. Retained voluntary non remunerated donors accounted for 19.5% with syphilis sero-positivity of 0.2%. Family replacement donors made up 10.6% of total blood units screened with a 2.0% anti-syphilis positive reaction and 1.0% co-infection. The prevalence of syphilis among blood donors in a centralized transfusion service may be low.

Orisaremi T.C.,University of Jos
African journal of reproductive health | Year: 2012

The study investigated how unequal gender relations inhibit the attainment of women's reproductive rights. It examined whether women can choose if and when to marry, who to marry/have sex with, ability to negotiate sex with spouse, and their access to family planning. Based on theoretical orientation from gender-sexuality framework, this paper employed the qualitative research design. The main respondents were female and male of various sociodemographic groups who were engaged through in-depth interviews and focus group discussion sessions. Findings show wide scale abuses of Tarok women's reproductive rights. Most of these abuses may be traced to traditional male-centred socio-cultural structures and patriarchy that help guarantee the immunity of male violators. It is concluded that in the context of unequal gender relations and dominance of patriarchy, the attainment of women's reproductive rights is a major challenge which has profound implications for life and death.

Ogbe A.E.,University of Jos
Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria | Year: 2012

Prevention of unintended pregnancies among HIV positive women is a key strategy in preventing the spread of the disease. Contraception is crucial to achieving this and consistent use of condom provides the dual advantage of prevention of pregnancy and reinfection with HIV and other sexually transmitted infections. The purpose of the study is to determine the contraceptive awareness among these women, the types of contraception being used as well as the prevalence and compliance with barrier contraception. A cross-sectional survey using an interviewer-administered proforma among HIV positive women within the reproductive age group receiving prevention of mother to child transmission (PMTCT) in Jos University Teaching Hospital. A total of 140 questionnaires were administered and retrieved. One hundred and thirty nine women (99.3%) had contraceptive awareness. Ninety eight of them (70%) were using contraception, among which 95(96.9% of contraceptive use) were using condom. The condom prevalence rate in the whole population was 67.8% The pattern of contraception showed that 46 (46.9%) used condom alone, 49 (50%) used condom with other methods; among which condom and injectables constitutedthe largest group (41 women, 41.8%). Out of those using condom, 43 (43.2%) were using it consistently. The prevalence of contraception, the use of barrier contraceptive and the rate of the combined use of condom with other contraceptive method, underscores the contraceptive awareness of these women as a means of preventing unplanned pregnancies and prevention of re-infection with HIV and other sexually transmitted infections.

Mandong B.M.,University of Jos
Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria | Year: 2013

In areas of parasitic endemicity, the occurrence of cancer that is not frequent may be linked with parasitic infection. Epidemiological correlates between some parasitic infections and cancer is strong, suggesting a strong aetiological association. The common parasites associated with human cancers are schistosomiasis, malaria, liver flukes (Clonorchis sinenses, Opistorchis viverrini). To review the pathology, literature and methods of diagnosis. Literature review from peer reviewed Journals cited in PubMed and local journals. Parasites may serve as promoters of cancer in endemic areas of infection.

Puscasu G.,University of Jos | Codres B.,University of Jos
International Journal of Neural Systems | Year: 2011

A new approach for nonlinear system identification and control based on modular neural networks (MNN) is proposed in this paper. The computational complexity of neural identification can be greatly reduced if the whole system is decomposed into several subsystems. This is obtained using a partitioning algorithm. Each local nonlinear model is associated with a nonlinear controller. These are also implemented by neural networks. The switching between the neural controllers is done by a dynamical switcher, also implemented by neural networks, that tracks the different operating points. The proposed multiple modelling and control strategy has been successfully tested on simulated laboratory scale liquid-level system. © 2011 World Scientific Publishing Company.

Auta A.,University of Jos
North American Journal of Medical Sciences | Year: 2012

Background: Malaria constitutes a major health problem, with children and pregnant women being the most vulnerable to its morbidity and mortality. Aim: To determine the demographic factors associated with the use of insecticide-treated nets among children and pregnant women in Nigeria. Materials and Methods: The study was based on data drawn from the Nigeria Demographic and Health Survey 2008 on the use of insecticide-treated nets among women and children. The survey was conducted in 34070 households and a total of 10,724 women aged 15-49 years participated in the survey. Data were entered into Minitab version 15 and the chi-square test for independence was performed to show association between variables. Results: The results revealed that 49.8% of children and 44% of pregnant women present in households that owe insecticide-treated nets slept under them on the night before the survey. Sleeping under an insecticide-treated nets among children was associated with (P<0.05) the age of a child, geopolitical zone, and wealth quintile while the use of insecticide-treated nets among pregnant women was associated with the education level and wealth quintile of households. Conclusion: The study demonstrated that some demographic factors are associated with the use of ITNs among children and pregnant women in Nigeria.

Ngwuluka N.C.,University of Jos
Preventive Medicine | Year: 2012

Human longevity and healthy ageing though controversial require extended investigations. Some studies have shown that ageing can be managed by reducing the amounts of free radicals the cells are exposed to. Oxidative stress has been shown to be combated by antioxidants and plant sources are known to generate antioxidants that are efficacious and low in toxicity. This review aims to enlighten on antioxidants from Bombax buonopozense and Bombax malabaricum for prevention, reversal or delay of age-related diseases. Furthermore, it advocates for more studies to enable the shift from research to commercial applications of the antioxidants as nutraceuticals in age management. © 2011 Elsevier Inc..

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