Carmo D.J.,University of Itauna |
Dias J.F.,University of Itauna |
Santos D.B.,Federal University of Minas Gerais
Materials Science and Technology (United Kingdom) | Year: 2012
The present work shows a steel structure with bainitic ferrite dispersed on a matrix of carbon enriched retained austenite. The steel was produced using an air melting technique, and it was austempered at 200°C for 240 h. The steel presents tensile strength of ∼2 GPa. The authors report the new results of resistance to high cycle rotating fatigue in high strength bending life limit 10 7 cycles. A fatigue strength of 593 MPa was obtained, a result that is higher than that presented by important engineering materials such as forged steel and austempered ductile iron, even with the presence of fracture type 'fish eye', which nucleates mainly on shrinkage defects. © 2012 Institute of Materials, Minerals and Mining.
Bueno A.C.,Federal University of Minas Gerais |
Ferreira R.C.,Federal University of Minas Gerais |
Barbosa F.I.,University of Itauna |
Jham B.C.,Midwestern University |
And 2 more authors.
Supportive Care in Cancer | Year: 2013
Purpose: The aim of this study was to evaluate periodontal changes after periodontal treatment and control in patients with malignant tumors of the upper aerodigestive tract who were submitted to radiotherapy with or without chemotherapy. Methods: We included all patients attending the Oncology Clinic of the Federal University of Minas Gerais, School of Dentistry. Clinical periodontal parameters obtained by a single calibrated examiner were evaluated at baseline, 10 days after radiotherapy, and 180 days after radiotherapy. Patients were grouped into healthy or periodontally diseased individuals. All patients received oral hygiene instructions, and the diseased patients received periodontal therapy at baseline. Comparisons between the groups were performed via the McNemar and Wilcoxon tests using SPSS v. 17.0. Results: A total of 28 patients were examined at baseline, of which 27 were examined 10 days after radiotherapy and 25 were examined 180 days after radiotherapy. The prevalence of periodontal disease at baseline was 67.9 % and did not decrease over time (p∈=∈1.0). There was a significant reduction in probing depth (PD), plaque index (PI), and bleeding on probing between baseline and follow-up, which was not observed in the attachment level (AL). Conclusions: Periodontal therapy was effective in reducing PI and improving periodontal status, as evidenced by the decreases in PD and the maintenance of AL. © 2012 Springer-Verlag Berlin Heidelberg.
Pernambuco A.P.,Federal University of Minas Gerais |
Pernambuco A.P.,University of Itauna |
Schetino L.P.L.,Health Science University |
Alvim C.C.,University of Alfenas |
And 4 more authors.
Clinical and Experimental Rheumatology | Year: 2013
Objectives. The aim of this study was to evaluate the plasma levels of IL-17A in fibromyalgia patients, and to look for any correlations between this data and the concentrations of some pro- and anti-inflammatory cytokines. Methods. We performed a study including 58 fibromyalgia patients and 39 healthy women matched for age and body mass index. The plasma levels of IL-17A and other pro- and anti-inflammatory cytokines were measured by using the technique of cytometric bead array (CBA). The analysis of differences between groups was performed using Mann-Whitney test and the analysis of the correlations by Spearman's correlation test. Results. The analyses showed that fibromyalgia patients present increased levels of IL-17A. They also revealed that plasma concentrations of IL17A positively correlate with levels of IL-2, IL-4 and IL-10, TNF and IFNγ. Conclusion. As far as we are aware, this is the first study to demonstrate increased levels of IL17A in fibromyalgia patients. The positive correlation between the levels of IL-17A and of other cytokines strengthens the hypothesis of the involvement of inflammatory mechanisms in the development of this syndrome. © Clinical and Experimental Rheumatology 2013.
Casali C.C.C.,University of Itauna |
Pereira A.P.M.,University of Sao Paulo |
Martinez J.A.B.,University of Sao Paulo |
De Souza H.C.D.,University of Sao Paulo |
Gastaldi A.C.,University of Sao Paulo
Obesity Surgery | Year: 2011
Background: This study seeks to assess the effect of inspiratory muscle training (IMT) on pulmonary function, respiratory muscle strength, and endurance in morbidly obese patients submitted to bariatric surgery. Methods: Thirty patients were randomly assigned to sham muscular training, or to IMT with a threshold device (40% of maximum inspiratory pressure, MIP), for 30 min/day, from the 2nd until 30th postoperative (PO) day. All of them were submitted to a standard respiratory kinesiotherapy and early deambulation protocol. Data on spirometry, maximum static respiratory pressures, and respiratory muscle endurance were collected on the PO days 2, 7, 14, and 30 in a blinded matter. Results: IMT enabled increases in PO MIP and endurance, and an earlier recovery of the spirometry parameters FEV 1, PEF, and FEF 25-75%. Comparing to preoperative values, MIP was increased by 13% at the 30th PO day in the trained group, whereas control group had a reduction of 8%, with higher values for the IMT group (30th PO, IMT-130.6∈±∈22.9 cmH 2O; controls-112.9∈±∈25.1 cmH 2O; p∈<∈0.05). Muscular endurance at the 30th PO day was increased in the trained group comparing to preoperative value (61.5∈±∈39.6 s vs 114.9∈±∈55.2 s; p∈<∈0.05), a finding not observed in the control group (81.7∈±∈44.3 vs 95.2∈±∈42.0 s). Conclusions: IMT improves inspiratory muscle strength and endurance and accounts for an earlier recovery of pulmonary airflows in morbidly obese patients submitted to bariatric surgery. © 2011 Springer Science + Business Media, LLC.
Cruz R.C.,Federal University of Minas Gerais |
Werneck S.M.C.,Federal University of Minas Gerais |
Oliveira C.S.,Federal University of Minas Gerais |
Santos P.C.,Federal University of Minas Gerais |
And 3 more authors.
Journal of Clinical Microbiology | Year: 2013
MIC assays with Paracoccidioides brasiliensis, the etiological agent of paracoccidioidomycosis, had been conducted with variable protocols, employing both macrodilution and microdilution tests and including differences in inoculum preparation, media used, incubation periods, and temperatures. Twenty-one clinical and environmental isolates of Paracoccidioides were tested using amphotericin B, itraconazole, ketoconazole, fluconazole, sulfamethoxazole, sulfamethoxazole-trimethoprim, and terbinafine, according to the National Committee for Clinical Laboratory Standards (National Committee for Clinical Laboratory Standards, document M27-A2, 2002), with modifications such as three medium formulations (RPMI 1640 medium, McVeigh and Morton [MVM] medium, and modified Mueller-Hinton [MMH] medium), two incubation temperatures (room temperature [25 to 28°C] and 37°C), and three incubation periods (7, 10, and 15 days). The antifungal activities were also classified as fungicidal or fungistatic. The best results were obtained after 15 days of incubation, which was chosen as the standard incubation time. The MICs for most individual isolates grown for the same length of time at the same temperature varied with the different media used (P<0.05). Of the isolates, 81% showed transition from the yeast to the mycelial form in RPMI 1640 medium at 37°C, independent of the presence of antifungals.MMHmedium appears to be a suitable medium for susceptibility testing of antifungal drugs with P. brasiliensis, except for sulfamethoxazole and the combination of sulfamethoxazole-trimethoprim, for which theMVMmedium yielded better results. The incubation temperature influenced the MICs, with, in general, higher MICs at 25°C (mycelial form) than at 37°C (P<0.05). Based on our results, we tentatively propose a microdilution assay protocol for susceptibility testing of antifungal drugs against Paracoccidioides. Copyright © 2013, American Society for Microbiology.