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Wozakowska-Kaplon B.,University of Humanities and Sciences in Kielce | Opolski G.,Medical University of Warsaw
PACE - Pacing and Clinical Electrophysiology | Year: 2010

Background: Measurement of natriuretic peptide's (NP) release in response to hemodynamic stress may be complementary to its baseline assessment in individuals. Atrial natriuretic peptide (ANP) and B-type natriuretic peptide (BNP) increase in patients with atrial fibrillation (AF) and decrease after successful cardioversion, suggesting that AF may stimulate secretion of NPs. However, there are conflicting data on the predictive value of NPs on the cardioversion outcome. Objectives: The purpose of this study was to investigate whether baseline and exercise-induced NP plasma levels can be useful in predicting successful cardioversion of persistent AF and maintenance of sinus rhythm during 6-month follow-up. Methods: A prospective study enrolled 77 consecutive subjects with persistent AF with normal left ventricular function, referred for elective cardioversion. Patients underwent a modified Bruce protocol treadmill exercise test 24 hours before cardioversion. Blood samples for ANP and BNP analyses were obtained at rest and 5 minutes after exercise peak. Results: The group of successful cardioversion and stable sinus rhythm presented higher exercise ANP (110.6 ± 41.2 pg/mL vs 43.8 ± 36.1; pg/mL, P < 0.0001) and lower BNP increase (5.2 ± 5.2 pg/mL vs 40.5 ± 34.2 pg/mL, P < 0.0001) than the group of unsuccessful cardioversion or AF recurrence. Using an optimized cutoff level of ≤12% of relative exercise-induced increase in BNP concentration, and of >50 pg/mL of ANP increase, successful cardioversion can be predicted with high accuracy. Conclusions: An increase in ANP and stability of BNP plasma concentration during exercise testing are independently associated with successful cardioversion and maintenance of sinus rhythm during 6-month follow-up. © 2010 Wiley Periodicals, Inc.

Stepien-Walek A.,University of Humanities and Sciences in Kielce
Cardiology Journal | Year: 2010

Intoxication caused by propafenone is very rare, and there are no known detailed epidemiological studies. We present the clinical manifestation of severe propafenone intoxication,successfully treated in a 17 year-old male. He was brought to the Intensive Care Unit after he had taken 3.0 g propafenone. The main clinical findings included: sudden cardiac arrest, coma, hypotension, left ventricular failure, bradycardia, sinoatrial block, atrioventricular junctional or/and ventricular tachycardia. During the treatment, transient heart pacing was performed and catecholamines were administered by means of continuous intravenous infusion of pressure doses as well as of infusion liquids. Cessation of toxic signs four hours after admission to hospital was observed. This relatively rare, fully symptomatic intoxication with propafenone deserved to be presented due to the drug's common usage in the treatment of dysrhythmia and life-threatening symptoms of overdosing. The course of the disease was dramatic and the patient survived only thanks to quick resuscitation, artificial ventilation, transient heart pacing, acidosis treatment and administration of pressure doses of catecholamines. © 2010 Via Medica.

Sadowski M.,Swietokrzyskie Centrum Kardiologii | Gasior M.,Silesian Center for Heart Diseases | Gierlotka M.,Silesian Center for Heart Diseases | Janion M.,Swietokrzyskie Centrum Kardiologii | And 2 more authors.
EuroIntervention | Year: 2011

Aims: Clinical outcomes in the treatment of acute ST-segment elevation myocardial infarction (STEMI) differ between men and women. The aim of the study was to compare results of STEMI management in a large multicentre national registry. Methods and results: A total of 456 hospitals (including 58 interventional centres) participated in the registry during one year. The study group consisted of 8,989 (34.5%) females and 17,046 (65.5%) males. Women were older (69.7±11 vs. 62±12 years; p<0.0001) and had more risk factors. Percutaneous coronary intervention was performed significantly less in women (47.8% vs. 57.4%; p<0.0001). There was a longer time delay in women at each stage of treatment. The incidence of in-hospital complications was higher in women. In-hospital (11.9% vs. 6.9%; p<0.0001) and 12-months (22% vs. 14.1%; p<0.0001) mortality was significantly higher in women. In multivariate analysis pulmonary oedema, cardiogenic shock, cardiac arrest, age, diabetes and anterior infarction significantly increased both in-hospital and long-term mortality. The in-hospital mortality was higher in the female group. Conclusions: Despite poor clinical characteristics, less than satisfactory management and a worse prognosis of STEMI in women, being a women itself is not a risk factor for increased long-term mortality, however, other well known risk factors affecting the prognosis relate frequently to the female gender. © Europa Edition 2011. All rights reserved.

Kotela A.,Central Research Hospital of Ministry of Interior | Kotela A.,Medical University of Warsaw | Kotela A.,University of Humanities and Sciences in Kielce | Kotela I.,Central Research Hospital of Ministry of Interior | Kotela I.,University of Humanities and Sciences in Kielce
International Orthopaedics | Year: 2014

Purpose: The aim of this study was to compare radiological results of total knee arthroplasties (TKAs) performed with patient-specific computed tomography (CT)-based instrumentation and conventional technique. The main study hypothesis was that CT-based patient-specific instrumentation (PSI) increases the accuracy of TKA.Methods: A prospective, randomized controlled trial was carried out between January and December 2011. A group of 112 patients who met the inclusion and exclusion criteria were enrolled in this study and randomly assigned to an experimental or control group. The experimental group comprised 52 patients operated on with the aid of the Signature™ CT-based implant positioning system. The control group consisted of 60 patients operated on using conventional instrumentation. The radiographic evaluation of implant positioning and overall coronal alignment was performed 12 months after the surgery by using standing anteroposterior radiographs of the entire lower limb and standard lateral radiographs.Results: Of the 112 patients initially enrolled for the study, 95 were included in the subsequent analyses. There were no statistically significant differences between groups in respect to coronal and sagittal component positioning and overall coronal alignment, except for frontal tibial component positioning. For this parameter, better results were obtained in the control group, with borderline statistical significance.Conclusions: Our study did not reveal superiority of the CT-based PSI system over conventional instrumentation. Further high-quality investigations of patient-specific systems are absolutely indispensable to assess their utility for TKA. In our opinion, the surgeon applying PSI technology is required to have advanced knowledge and considerable experience with the conventional method. © 2014, The Author(s).

Namiesnik J.,Technical University of Gdansk | Rabajczyk A.,University of Humanities and Sciences in Kielce
Critical Reviews in Analytical Chemistry | Year: 2010

There are many sources of heavy metals in the environment. They can get there from the atmosphere as a result of intensive rain or snowfall, or they can be eroded out of the bedrock or soil. Larger amounts, often exceeding permitted concentrations, are most frequently due to emissions/discharges from industrial areas. The great variety of sources and physico-chemical conditionsmeans that an element can occur inmany different forms. That is why any assessment of the degree of contamination of the environment should be carried out not only from the point of view of the total amount of a metal found in environmental samples; it is also very important to know the contents of stable species of metals, constituting a potential reserve in the biocirculation. Moreover, the forms of occurrence of aluminum determine its toxicity or the synergistic relationships it enters into with other substances, which in turn determine its uptake and absorption by living organisms. © Taylor and Francis Group, LLC.

Namiesnik J.,Technical University of Gdansk | Rabajczyk A.,University of Humanities and Sciences in Kielce
Chemical Speciation and Bioavailability | Year: 2010

Surface waters can be contaminated in many ways, e.g., by solutions and suspended matter. Moreover, insoluble substances in colloidal form, in suspension or adsorbed on solid bodies can dissolve in response to changing physical and chemical conditions and become a secondary source of surface water pollution, thereby endangering wildlife. In addition, if we take into account varying rates of flow, contaminants can be transported over considerable distances. Hydrological processes, which determine factors, such as the rate of sedimentation, also influence the quality of surface waters; bottom sediments can contain large quantities of accumulated organic and inorganic compounds, including heavy metals. The physical and chemical properties of aquatic ecosystems are characterized by a number of interdependent parameters. Hence, factors such as temperature, oxygen content and pH of a water body can alter the solubility of the salts present in it, the forms of occurrence of particular species, as well as their bioavailability and toxicity. Thus it is necessary to determine the various species of metals present in the different compartments of the aquatic ecosystem.

Choma J.,University of Humanities and Sciences in Kielce
Ochrona Srodowiska | Year: 2011

Adsorption processes involving new generation adsorbents can noticeably facilitate the removal of such toxic substances as heavy metal ions, complex anions and various organic pollutants. These new adsorbents include siliceous and carbonaceous mesoporous materials. Their unique adsorption properties are attributable to a high surface area, uniform and accessible pores of desired sizes, a large pore volume and an interconnected structure of pores. The well-developed and active surface of these materials can be easily modified, thus enabling the preparation of adsorbents with desired adsorption properties. It has been demonstrated that the incorporation/embedding of metal, metal oxide and inorganic salt nanoparticles into the siliceous or carbonaceous matrix of these materials may also allow for tailoring their adsorption properties. In this work presented are the available methods for the synthesis of ordered mesoporous siliceous and carbonaceous materials. Special emphasis is placed on the modification methods that allow for the use of mesoporous materials in water treatment. Examples of methods for the synthesis of carbon-based composites with metal, metal oxide and inorganic salt nanoparticles are described, considering the beneficial effect of those materials on the adsorption-based water treatment process. It can be expected that in near future the role of ordered mesoporous carbon and silica materials in water treatment will gain in importance.

The aim of this paper is to present a distribution of new localities of Doronicum austriacum Jacq. which have been noticed in the upper section of Kamienna river valley (Wyżyna Małopolska Upland), to describe number of individuals of populations and to characterize habitats of this species in study area. In the Kamienna river valley five new localities of D. austriacum have been found. On most of the sites the species grows in brushwood of marshy meadow. All the new localities are placed in one ATPOL square (10 × 10 km) - EE 45 and delimit the north range of the species in Poland.

Janowska G.,Technical University of Lodz | Kucharska-Jastrzabek A.,Technical University of Lodz | Rybinski P.,University of Humanities and Sciences in Kielce
Journal of Thermal Analysis and Calorimetry | Year: 2011

This article presents the effect of the method of NBR cross linking on the thermal properties, flammability and fire hazard of its nanocomposites containing modified montmorillonite (NanoBent or Nanofil), using test results obtained by means of a derivatograph, oxygen index and cone calorimetry. It has been found that the thermal stability and flammability of the nanocomposites investigated depend on both the rubber network structure and the type of montmorillonite. The nanoadditives used reduce the flammability of cross-linked nitrile rubber and considerably limit its fire hazard. © 2011 The Author(s).

Rybinski P.,University of Humanities and Sciences in Kielce | Janowska G.,Technical University of Lodz | Jozwiak M.,University of Humanities and Sciences in Kielce | Pajak A.,Technical University of Lodz
Journal of Thermal Analysis and Calorimetry | Year: 2012

This article presents a procedure of the activation of halloysite and a method of the synthesis of nucleus-sheath type filler. The effects of the nanoadditives obtained on the thermal properties, flammabilities and fire hazards of peroxide and sulfur vulcanizates of NBR and SBR rubbers, are discussed. Based on the test results obtained by derivatography, oxygen index, FAA microcalorimeter and cone calorimeter, the thermal stability, flammability, and fire hazard of the nanocomposites investigated were determined. The results obtained were interpreted from the point of view of the chemical structure of the diene elastomers investigated, their spatial network structure, and the method of halloysite modification. © The Author(s) 2011.

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