Hong Kong, China

University of Hong Kong

hku.hk/
Hong Kong, China

The University of Hong Kong is the oldest tertiary institution in Hong Kong. Its motto is "Sapientia et Virtus" in Latin, meaning "wisdom and virtue", and "明德格物" in Chinese. The medium of instruction in most classes is English. The school adopts the problem-based learning teaching strategy which aims to train students' problem solving skills. It has a great achievement in Humanities, Legal subjects, Political science, Biological science and Medicine. Wikipedia.


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Patent
University of Hong Kong | Date: 2017-03-01

Methods of diagnosis and/or prognosis of malignant disease from pleural effusion samples are disclosed. The methods typically include determining the normalized intensity of one or more biomarkers, such as acetone and 3-hydroxybutyate, in pleural effusion samples using nuclear magnetic resonance (NMR), such as proton NMR (^(1)H-NMR) spectroscopy. Reference values for malignant disease diagnosis using the disclosed biomarkers are provided. Reference values for prognosis of median survival time based on the disclosed biomarkers are also provided.


Patent
University of Hong Kong | Date: 2016-11-18

Novel and advantageous insulator discs with embedded resonator coils are provided. By linking the insulator discs in a series using an appropriate mechanical mechanism, the insulator discs form an insulator or insulator string for a high power transmission line system. The resonator coils embedded inside the insulator discs therefore form a series of relay resonators that can be used for wireless power transfer through the principle of near-field magnetic coupling and resonance. The insulator string can provide the simultaneous functions of voltage insulation and wireless power transfer over the length of the string. Applications include, but not limited to, wireless power transfer in a high-voltage environment such as that encountered in high-voltage power transmission line systems.


The present invention provides a method for evaluation of risk and progression of autoimmune diabetes in mammalian subjects. The method includes measuring the enzymatic activities and/or protein concentrations of neutrophil elastase and proteinase 3 in a subject and comparing the measured levels of these proteases to respective reference levels.


Patent
University of Hong Kong | Date: 2016-12-02

Disclosed are conjugates, compositions, and methods that include or use one or more gold(III) porphyrin complexes. Preferred conjugates are gold(III) porphyrin-poly(ethylene glycol) (PEG) conjugates. Preferred compositions and methods include or use such gold(III) porphyrin-PEG conjugates. Disclosed is a method for treatment of cancer comprising administering to a human in need of such treatment a composition containing a therapeutically effective amount of gold(III) porphyrin-poly(ethylene glycol) (PEG) conjugates. The gold(III) porphyrin-PEG conjugates can be in the form of nanostructures formed by self-assembly of the gold(III) porphyrin-PEG conjugates; or nanocomposites formed by encapsulation of other therapeutic agents by the nanostructures of gold(III) porphyrin-PEG conjugates.


Patent
University of Hong Kong | Date: 2016-12-06

Self-propelling, programmable nanoscopic motors capable of harvesting energy from absorbed photons and undergoing subsequent photoeletrochemical (PEC) reactions are provided. A nanomotor can have a three-dimensional Janus configuration and can sense the direction of a light source. By controlling the zeta potential of different parts of the nanomotor with chemical modifications, the nanomotor can be programmed to show either positive phototaxis or negative phototaxis.


Methods for the fabrication of transparent conductive metal nanowire networks are provided, as well as metal nanowire networks fabricated by such methods. A metal nanowire network can be immersed in a solution and illuminated for a duration of time. Selective nucleation and growth of metal nanoparticles can be induced at the junctions between metal nanowires.


Patent
University of Hong Kong | Date: 2016-11-29

The present disclosure relates to the design and generation of stapled helical peptides that perturb protein-protein interactions (PPIs). The methods disclosed herein for preparing stapled peptides involve providing a peptide having a first amino acid that is functionalized with a salicylaldehyde ester side group and a second amino acid functionalized with a 1,2-hydroxyl amine side group; reacting the first and second amino acids to generate an N,O-benzylidene acetal moiety; and performing acidolysis of the resultant N,O-benzylidene acetal moiety to generate the stapled peptide. In many forms, the stapled helical peptides described herein are not hydrophobic.


Patent
University of Hong Kong | Date: 2017-01-12

Described herein are compounds that are platinum emitters and, more particularly compounds that are platinum emitters of blue light and their applications in blue emitting organic light-emitting diodes (OLED). Also disclosed herein are devices that comprise the platinum emitters and methods of making and using the platinum emitters.


A highly rigid tetradentate ligand is combined with a gold(III) ion as a thermally stable tetradentate gold(III) complex. The tetradentate gold(III) complex is a tetradentate gold(III) compound that can be used as a light-emitting material which can be used for fabricated of light-emitting devices such as an organic light-emitting diode (OLED). The tetradentate gold(III) compound can be deposited as a layer or a component of a layer using a solution-process or a vacuum deposition process. The luminescent tetradentate gold(III) compounds are robust and can provide electroluminescence (EL) with a high efficiency and brightness.


A fast algorithm is used to study the transient behavior due to the step-like pulse. This algorithm consists of two parts: The algorithm I reduces the computational complexity to T^(0)N^(3 )for large systems as long as T

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