Hong Kong, China
Hong Kong, China

The University of Hong Kong is the oldest tertiary institution in Hong Kong. Its motto is "Sapientia et Virtus" in Latin, meaning "wisdom and virtue", and "明德格物" in Chinese. The medium of instruction in most classes is English. The school adopts the problem-based learning teaching strategy which aims to train students' problem solving skills. It has a great achievement in Humanities, Legal subjects, Political science, Biological science and Medicine. Wikipedia.


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Annexin A3 (ANAX3) is utilized as a biomarker for the diagnosis and prognosis of hepatocellular carcinoma (HCC) and the utilization of a monoclonal antibody against ANXA3 or antisense polynucleotide against ANXA3 mRNA for the suppression or treatment of HCC, alone or in combination with other HCC treatment. Monoclonal antibody against ANXA3 can be administered for the suppression of tumor growth, metastasis, and chemoresistance.


Patent
University of Hong Kong | Date: 2017-03-01

Methods of diagnosis and/or prognosis of malignant disease from pleural effusion samples are disclosed. The methods typically include determining the normalized intensity of one or more biomarkers, such as acetone and 3-hydroxybutyate, in pleural effusion samples using nuclear magnetic resonance (NMR), such as proton NMR (^(1)H-NMR) spectroscopy. Reference values for malignant disease diagnosis using the disclosed biomarkers are provided. Reference values for prognosis of median survival time based on the disclosed biomarkers are also provided.


High-quality non-stoichiometric NiO_(x )nanoparticles are synthesized by a facile chemical precipitation method. The NiO_(x )film can function as an effective p-type semiconductor or hole transport layer (HTL) without any post-treatments, while offering wide temperature applicability from room-temperature to 150 C. For demonstrating the potential applications, high efficiency is achieved in organic solar cells using NiO_(x )HTL. Better performance in NiO_(x )based organic light emitting diodes is obtained as compared to devices using PEDOT:PSS. The solution-processed NiO_(x )semiconductors at room temperature can favor a wide-range of applications of large-area and flexible optoelectronics.


Patent
University of Hong Kong | Date: 2016-11-18

Novel and advantageous insulator discs with embedded resonator coils are provided. By linking the insulator discs in a series using an appropriate mechanical mechanism, the insulator discs form an insulator or insulator string for a high power transmission line system. The resonator coils embedded inside the insulator discs therefore form a series of relay resonators that can be used for wireless power transfer through the principle of near-field magnetic coupling and resonance. The insulator string can provide the simultaneous functions of voltage insulation and wireless power transfer over the length of the string. Applications include, but not limited to, wireless power transfer in a high-voltage environment such as that encountered in high-voltage power transmission line systems.


The present invention provides a method for evaluation of risk and progression of autoimmune diabetes in mammalian subjects. The method includes measuring the enzymatic activities and/or protein concentrations of neutrophil elastase and proteinase 3 in a subject and comparing the measured levels of these proteases to respective reference levels.


Patent
University of Hong Kong | Date: 2016-11-29

The present disclosure relates to the design and generation of stapled helical peptides that perturb protein-protein interactions (PPIs). The methods disclosed herein for preparing stapled peptides involve providing a peptide having a first amino acid that is functionalized with a salicylaldehyde ester side group and a second amino acid functionalized with a 1,2-hydroxyl amine side group; reacting the first and second amino acids to generate an N,O-benzylidene acetal moiety; and performing acidolysis of the resultant N,O-benzylidene acetal moiety to generate the stapled peptide. In many forms, the stapled helical peptides described herein are not hydrophobic.


Patent
University of Hong Kong | Date: 2017-04-05

A correlated colour temperature control system (1) for a LED lighting system (2) having at least two LED sources (3, 4) with different correlated colour temperatures. The LED lighting system (2) has a combined correlated colour temperature resulting from the combination of the different correlated colour temperatures of the at least two LED sources (3, 4), and a combined luminous flux resulting from the combination of the luminous fluxes of the at least two LED sources (3, 4), with each LED source being supplied with a supply current. The correlated colour temperature control system (1) comprises a controller (5) to independently control one or both of the duty cycle and amplitude of each supply current, the duty cycle or amplitude of each supply current being varied by the controller in a non-linear relationship with the duty cycle or amplitude of at least one other of the supply currents, to generate a desired combined correlated colour temperature for the LED lighting system (2) at a desired combined luminous flux for the LED lighting system (3, 4). An associated method is also provided.


In one embodiment, provided are a new class of diarylethene-containing photochromic compounds with the incorporation of silicon-or phosphorus-containing heterocycles into the ethene part of the diarylethene backbone that has been shown to be capable of displaying tunable, robust and thermally stable photochromic properties. Also provided are methods for synthesizing these compounds, as well as uses of these compounds as these compounds may be used as the photochromic layer in an optical recording material and other optical functioning devices.


Methods of treating autophagy related diseases, e. g. cancer and malaria, using novel autophagy inhibiting agents are described.


Atmospheric pressure megavolt electrostatic field ionization desorption (APME-FID) method generates ions directly from the surface of sample (2) connected to a high electrical voltage generator (1) at megavolt conditions. Megavolt electrostatic potential is generated and gradually accumulated directly on the sample (2) surface by a Van de Graaff generator without causing damage to the sample (2). Therefore, when coupled with mass spectrometric system, the APME-FID-MS method enables direct detection of analytes on the surface of samples in different sizes and diverse types.

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