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REDWOOD CITY, Calif. and RESEARCH TRIANGLE PARK, N.C., May 26, 2017 (GLOBE NEWSWIRE) -- Ocera Therapeutics, Inc. (NASDAQ:OCRX), a clinical stage biopharmaceutical company focused on acute and chronic liver diseases, today announced that it will host a Key Opinion Leader call on the topic of Hepatic Encephalopathy and Other Complications of Liver Disease, on Friday June 2, 2017 at 11:00 am Eastern Time. KOL Call:  Hepatic Encephalopathy and Other Complications of Liver Disease The call will feature a conversation with key opinion leader Robert S. Rahimi, MD, MSCR (Baylor Health Care System), who will discuss the unmet needs in hepatic encephalopathy (HE) and other complications of liver disease. Dr. Rahimi will be available to answer questions at the conclusion of the call. Ocera Therapeutics' management will discuss the Company’s ongoing clinical development of OCR-002 (ornithine phenylacetate). OCR-002 is in development in both an intravenous formulation which is well-suited for hospitalized population with overt HE, and an oral formulation for use as a step-down therapy and to provide a chronic use option to maintain remission of HE in patients with liver cirrhosis. Robert Rahimi, MD, MSCR is board certified in Transplant Hepatology, Gastroenterology, and Internal Medicine, and a practicing physician at Baylor Health Care System. He currently treats patients with a variety of liver diseases, including chronic liver disease, liver cancer, liver failure, metabolic and autoimmune diseases of the liver, viral hepatitis, complications of cirrhosis, and liver transplantation. Dr. Rahimi has authored several research articles on improving the outcomes of patients with advanced liver disease. His research includes studying new treatments in development for Hepatitis, Liver Cancer, Cirrhosis, Liver Transplant, Acute Liver Failure, Chronic Liver Diseases, Hepatic Encephalopathy, and Metabolic Liver Diseases.  Dr. Rahimi holds a Master of Science in Applied Physiology from Finch University of Health Sciences in North Chicago and medical degree from Chicago Medical School. Hepatic encephalopathy is a debilitating and progressive complication of liver cirrhosis or liver failure, marked by mental changes including confusion, impaired motor skills, disorientation, and in its more severe form, stupor, coma and even death. Ocera Therapeutics, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of OCR-002 (ornithine phenylacetate) in both intravenous and oral formulations. OCR-002 is an ammonia scavenger and has been granted orphan drug designation and Fast Track status by the U.S. Food and Drug Administration (FDA) for the treatment of hyperammonemia and resultant hepatic encephalopathy in patients with acute liver failure and acute-on-chronic liver disease. For additional information, please see www.ocerainc.com.


REDWOOD CITY, Calif. and RESEARCH TRIANGLE PARK, N.C., May 26, 2017 (GLOBE NEWSWIRE) -- Ocera Therapeutics, Inc. (NASDAQ:OCRX), a clinical stage biopharmaceutical company focused on acute and chronic liver diseases, today announced that it will host a Key Opinion Leader call on the topic of Hepatic Encephalopathy and Other Complications of Liver Disease, on Friday June 2, 2017 at 11:00 am Eastern Time. KOL Call:  Hepatic Encephalopathy and Other Complications of Liver Disease The call will feature a conversation with key opinion leader Robert S. Rahimi, MD, MSCR (Baylor Health Care System), who will discuss the unmet needs in hepatic encephalopathy (HE) and other complications of liver disease. Dr. Rahimi will be available to answer questions at the conclusion of the call. Ocera Therapeutics' management will discuss the Company’s ongoing clinical development of OCR-002 (ornithine phenylacetate). OCR-002 is in development in both an intravenous formulation which is well-suited for hospitalized population with overt HE, and an oral formulation for use as a step-down therapy and to provide a chronic use option to maintain remission of HE in patients with liver cirrhosis. Robert Rahimi, MD, MSCR is board certified in Transplant Hepatology, Gastroenterology, and Internal Medicine, and a practicing physician at Baylor Health Care System. He currently treats patients with a variety of liver diseases, including chronic liver disease, liver cancer, liver failure, metabolic and autoimmune diseases of the liver, viral hepatitis, complications of cirrhosis, and liver transplantation. Dr. Rahimi has authored several research articles on improving the outcomes of patients with advanced liver disease. His research includes studying new treatments in development for Hepatitis, Liver Cancer, Cirrhosis, Liver Transplant, Acute Liver Failure, Chronic Liver Diseases, Hepatic Encephalopathy, and Metabolic Liver Diseases.  Dr. Rahimi holds a Master of Science in Applied Physiology from Finch University of Health Sciences in North Chicago and medical degree from Chicago Medical School. Hepatic encephalopathy is a debilitating and progressive complication of liver cirrhosis or liver failure, marked by mental changes including confusion, impaired motor skills, disorientation, and in its more severe form, stupor, coma and even death. Ocera Therapeutics, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of OCR-002 (ornithine phenylacetate) in both intravenous and oral formulations. OCR-002 is an ammonia scavenger and has been granted orphan drug designation and Fast Track status by the U.S. Food and Drug Administration (FDA) for the treatment of hyperammonemia and resultant hepatic encephalopathy in patients with acute liver failure and acute-on-chronic liver disease. For additional information, please see www.ocerainc.com.


REDWOOD CITY, Calif. and RESEARCH TRIANGLE PARK, N.C., May 26, 2017 (GLOBE NEWSWIRE) -- Ocera Therapeutics, Inc. (NASDAQ:OCRX), a clinical stage biopharmaceutical company focused on acute and chronic liver diseases, today announced that it will host a Key Opinion Leader call on the topic of Hepatic Encephalopathy and Other Complications of Liver Disease, on Friday June 2, 2017 at 11:00 am Eastern Time. KOL Call:  Hepatic Encephalopathy and Other Complications of Liver Disease The call will feature a conversation with key opinion leader Robert S. Rahimi, MD, MSCR (Baylor Health Care System), who will discuss the unmet needs in hepatic encephalopathy (HE) and other complications of liver disease. Dr. Rahimi will be available to answer questions at the conclusion of the call. Ocera Therapeutics' management will discuss the Company’s ongoing clinical development of OCR-002 (ornithine phenylacetate). OCR-002 is in development in both an intravenous formulation which is well-suited for hospitalized population with overt HE, and an oral formulation for use as a step-down therapy and to provide a chronic use option to maintain remission of HE in patients with liver cirrhosis. Robert Rahimi, MD, MSCR is board certified in Transplant Hepatology, Gastroenterology, and Internal Medicine, and a practicing physician at Baylor Health Care System. He currently treats patients with a variety of liver diseases, including chronic liver disease, liver cancer, liver failure, metabolic and autoimmune diseases of the liver, viral hepatitis, complications of cirrhosis, and liver transplantation. Dr. Rahimi has authored several research articles on improving the outcomes of patients with advanced liver disease. His research includes studying new treatments in development for Hepatitis, Liver Cancer, Cirrhosis, Liver Transplant, Acute Liver Failure, Chronic Liver Diseases, Hepatic Encephalopathy, and Metabolic Liver Diseases.  Dr. Rahimi holds a Master of Science in Applied Physiology from Finch University of Health Sciences in North Chicago and medical degree from Chicago Medical School. Hepatic encephalopathy is a debilitating and progressive complication of liver cirrhosis or liver failure, marked by mental changes including confusion, impaired motor skills, disorientation, and in its more severe form, stupor, coma and even death. Ocera Therapeutics, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of OCR-002 (ornithine phenylacetate) in both intravenous and oral formulations. OCR-002 is an ammonia scavenger and has been granted orphan drug designation and Fast Track status by the U.S. Food and Drug Administration (FDA) for the treatment of hyperammonemia and resultant hepatic encephalopathy in patients with acute liver failure and acute-on-chronic liver disease. For additional information, please see www.ocerainc.com.


REDWOOD CITY, Calif. and RESEARCH TRIANGLE PARK, N.C., May 26, 2017 (GLOBE NEWSWIRE) -- Ocera Therapeutics, Inc. (NASDAQ:OCRX), a clinical stage biopharmaceutical company focused on acute and chronic liver diseases, today announced that it will host a Key Opinion Leader call on the topic of Hepatic Encephalopathy and Other Complications of Liver Disease, on Friday June 2, 2017 at 11:00 am Eastern Time. KOL Call:  Hepatic Encephalopathy and Other Complications of Liver Disease The call will feature a conversation with key opinion leader Robert S. Rahimi, MD, MSCR (Baylor Health Care System), who will discuss the unmet needs in hepatic encephalopathy (HE) and other complications of liver disease. Dr. Rahimi will be available to answer questions at the conclusion of the call. Ocera Therapeutics' management will discuss the Company’s ongoing clinical development of OCR-002 (ornithine phenylacetate). OCR-002 is in development in both an intravenous formulation which is well-suited for hospitalized population with overt HE, and an oral formulation for use as a step-down therapy and to provide a chronic use option to maintain remission of HE in patients with liver cirrhosis. Robert Rahimi, MD, MSCR is board certified in Transplant Hepatology, Gastroenterology, and Internal Medicine, and a practicing physician at Baylor Health Care System. He currently treats patients with a variety of liver diseases, including chronic liver disease, liver cancer, liver failure, metabolic and autoimmune diseases of the liver, viral hepatitis, complications of cirrhosis, and liver transplantation. Dr. Rahimi has authored several research articles on improving the outcomes of patients with advanced liver disease. His research includes studying new treatments in development for Hepatitis, Liver Cancer, Cirrhosis, Liver Transplant, Acute Liver Failure, Chronic Liver Diseases, Hepatic Encephalopathy, and Metabolic Liver Diseases.  Dr. Rahimi holds a Master of Science in Applied Physiology from Finch University of Health Sciences in North Chicago and medical degree from Chicago Medical School. Hepatic encephalopathy is a debilitating and progressive complication of liver cirrhosis or liver failure, marked by mental changes including confusion, impaired motor skills, disorientation, and in its more severe form, stupor, coma and even death. Ocera Therapeutics, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of OCR-002 (ornithine phenylacetate) in both intravenous and oral formulations. OCR-002 is an ammonia scavenger and has been granted orphan drug designation and Fast Track status by the U.S. Food and Drug Administration (FDA) for the treatment of hyperammonemia and resultant hepatic encephalopathy in patients with acute liver failure and acute-on-chronic liver disease. For additional information, please see www.ocerainc.com.


REDWOOD CITY, Calif. and RESEARCH TRIANGLE PARK, N.C., May 26, 2017 (GLOBE NEWSWIRE) -- Ocera Therapeutics, Inc. (NASDAQ:OCRX), a clinical stage biopharmaceutical company focused on acute and chronic liver diseases, today announced that it will host a Key Opinion Leader call on the topic of Hepatic Encephalopathy and Other Complications of Liver Disease, on Friday June 2, 2017 at 11:00 am Eastern Time. KOL Call:  Hepatic Encephalopathy and Other Complications of Liver Disease The call will feature a conversation with key opinion leader Robert S. Rahimi, MD, MSCR (Baylor Health Care System), who will discuss the unmet needs in hepatic encephalopathy (HE) and other complications of liver disease. Dr. Rahimi will be available to answer questions at the conclusion of the call. Ocera Therapeutics' management will discuss the Company’s ongoing clinical development of OCR-002 (ornithine phenylacetate). OCR-002 is in development in both an intravenous formulation which is well-suited for hospitalized population with overt HE, and an oral formulation for use as a step-down therapy and to provide a chronic use option to maintain remission of HE in patients with liver cirrhosis. Robert Rahimi, MD, MSCR is board certified in Transplant Hepatology, Gastroenterology, and Internal Medicine, and a practicing physician at Baylor Health Care System. He currently treats patients with a variety of liver diseases, including chronic liver disease, liver cancer, liver failure, metabolic and autoimmune diseases of the liver, viral hepatitis, complications of cirrhosis, and liver transplantation. Dr. Rahimi has authored several research articles on improving the outcomes of patients with advanced liver disease. His research includes studying new treatments in development for Hepatitis, Liver Cancer, Cirrhosis, Liver Transplant, Acute Liver Failure, Chronic Liver Diseases, Hepatic Encephalopathy, and Metabolic Liver Diseases.  Dr. Rahimi holds a Master of Science in Applied Physiology from Finch University of Health Sciences in North Chicago and medical degree from Chicago Medical School. Hepatic encephalopathy is a debilitating and progressive complication of liver cirrhosis or liver failure, marked by mental changes including confusion, impaired motor skills, disorientation, and in its more severe form, stupor, coma and even death. Ocera Therapeutics, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of OCR-002 (ornithine phenylacetate) in both intravenous and oral formulations. OCR-002 is an ammonia scavenger and has been granted orphan drug designation and Fast Track status by the U.S. Food and Drug Administration (FDA) for the treatment of hyperammonemia and resultant hepatic encephalopathy in patients with acute liver failure and acute-on-chronic liver disease. For additional information, please see www.ocerainc.com.


The International Association of HealthCare Professionals is pleased to welcome Kenneth R. Brooks, MD, FAAOS, Orthopedic Surgeon, to their prestigious organization with his upcoming publication in The Leading Physicians of the World. Dr. Brooks is a highly-trained and qualified orthopedic surgeon with a vast expertise in all facets of his work, especially sports medicine, adult reconstructive orthopedic surgery, as well as hip, knee, wrist and hand osteoarthritis. Dr. Brooks has been in practice for more than six years and is currently serving as an Assistant Professor at the University of Texas Medical Branch at Galveston. Furthermore, Dr. Brooks is affiliated with Memorial Hermann Southeast Hospital, John Sealy Hospital, Christus St. John Hospital, and UTMB Specialty Care Center at Victory Lakes. Dr. Brooks’ career in medicine began in 2000 when he graduated with his Medical Degree from The Chicago Medical School, Finch University of Health Sciences. Following his graduation, Dr. Brooks completed his internship and then residency at the University of Medicine and Dentistry of New Jersey. He then went on to undertake his fellowship training at Wayne State University, followed by an additional fellowship at completed at the University of Texas Health Science Center. Dr Brooks is board certified in Orthopedic Surgery, and has earned the coveted title of Fellow of the American Academy of Orthopaedic Surgeons. To keep up to date with the latest advances and developments in his field, Dr. Brooks maintains professional memberships with the American Orthopaedic Society for Sports Medicine, the American Academy of Orthopaedic Surgeons, and the Texas Orthopaedic Association. For his excellence, Dr. Brooks has been recognized with a Patient’s Choice Award in 2013, a Compassionate Doctor Recognition in 2013, and a Rose Award for Outstanding Service Excellence by Oregon Health Sciences University in 2000 and 2001. Dr. Brooks believes effective communication is the foundation for a successful physician-patient partnership. He attributes his great success to his hard work, staying focused, his love for the field and seeing his patients get healthier, and the support from his family. When he is not working, Dr. Brooks enjoys coaching youth soccer, golfing, body surfing, and spending time with his family. Learn more about Dr. Brooks by reading his upcoming publication in The Leading Physicians of the World. FindaTopDoc.com is a hub for all things medicine, featuring detailed descriptions of medical professionals across all areas of expertise, and information on thousands of healthcare topics.  Each month, millions of patients use FindaTopDoc to find a doctor nearby and instantly book an appointment online or create a review.  FindaTopDoc.com features each doctor’s full professional biography highlighting their achievements, experience, patient reviews and areas of expertise.  A leading provider of valuable health information that helps empower patient and doctor alike, FindaTopDoc enables readers to live a happier and healthier life.  For more information about FindaTopDoc, visit:http://www.findatopdoc.com


In 1995, 2005 and 2011, cross-sectional studies of 611 parturients at the Centre Hospitalier de Libreville in Gabon assessed the prevalence of maternal malaria and anaemia; two indicators of poor pregnancy outcomes. The prevalence of Plasmodium falciparum infection in maternal peripheral blood decreased from 25% in 2005 to 6% in 2011. Parasite density was significantly lower in 2005 (31 p/μL) than in 1995 (1,240 p/μL) or 2011 (35,055 p/μL). Anaemia prevalence was high (>50%) in 1995 and in 2005, but fell by more than 50% (24%) in 2011. After implementation of new malaria prevention strategies during pregnancy, the prevalence of both maternal peripheral P. falciparum infection and anaemia fell. Studies are necessary to assess the efficacy of these strategies and to seek other causes of anaemia.


The rising number of dental implants placed in the treatment of partial or full edentulism confronts the clinician with more implant-related pathology. The presence of a transmucosal component resembles the natural tooth and makes it likewise prone to oral plaque adhesion and plaque-related diseases. However, non-plaque-related diseases can also occur around implants. This clinical case describes the historical background, the diagnosis, treatment and follow-up of a 33-year-old female patient presenting with a peripheral giant cell granuloma surrounding a maxillary implant. Diagnosis was established by histopathologic analysis. The treatment consisted of complete excision and bone curettage, strict plaque-control and intensive aftercare. Eight months later, no recurrence had been observed. Nevertheless, the soft tissues did not return exactly to their original situation. Early diagnosis by means of a biopsy is crucial when an epulis is detected. This results in both a less invasive excision and a more favorable aesthetic outcome.

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